{"id":"https://openalex.org/W41210520","doi":"https://doi.org/10.1007/978-1-4612-2092-3_6","title":"Frequency of BRCA2 Mutations in Women with Early Onset Breast Cancer Drawn from a Population-Based Study","display_name":"Frequency of BRCA2 Mutations in Women with Early Onset Breast Cancer Drawn from a Population-Based Study","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W41210520","doi":"https://doi.org/10.1007/978-1-4612-2092-3_6","mag":"41210520"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4612-2092-3_6","doi":"https://doi.org/10.1007/978-1-4612-2092-3_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-2092-3_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hormonal Carcinogenesis III","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4242635321","display_name":"Hormonal Carcinogenesis III"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074840024","display_name":"Kathleen E. Malone","orcid":"https://orcid.org/0000-0002-5643-6714","observed_orcids":["https://orcid.org/0000-0002-5643-6714"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathleen E. Malone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111802584","display_name":"Janet R. Daling","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Janet R. Daling","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031151217","display_name":"Nicola M. Suter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicola M. Suter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023546258","display_name":"Kara L. Cushing\u2010Haugen","orcid":"https://orcid.org/0000-0003-2993-0191","observed_orcids":["https://orcid.org/0000-0003-2993-0191"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kara Cushing","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086265965","display_name":"Thora J. J\u00f3nasd\u00f3ttir","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thora Jonnasdottir","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045178497","display_name":"Elaine A. Ostrander","orcid":"https://orcid.org/0000-0001-6075-9738","observed_orcids":["https://orcid.org/0000-0001-6075-9738"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elaine A. Ostrander","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01548387,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"70","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brca2-mutation","display_name":"BRCA2 mutation","score":0.9549999833106995},{"id":"https://openalex.org/keywords/brca1-mutation","display_name":"BRCA1 mutation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/early-onset-breast-cancer","display_name":"early-onset breast cancer","score":0.9079999923706055},{"id":"https://openalex.org/keywords/hereditary-breast-cancer","display_name":"hereditary breast cancer","score":0.7139999866485596},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.5440000295639038},{"id":"https://openalex.org/keywords/mutation-frequency","display_name":"mutation frequency","score":0.7570000290870667},{"id":"https://openalex.org/keywords/general-population","display_name":"general population","score":0.6269999742507935},{"id":"https://openalex.org/keywords/autosomal-dominant-gene","display_name":"autosomal dominant gene","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.7538765072822571},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7131394147872925},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5798351764678955},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5231289267539978},{"id":"https://openalex.org/C2991661194","wikidata":"https://www.wikidata.org/wiki/Q217690","display_name":"Lifetime risk","level":3,"score":0.5199638605117798},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4985530376434326},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.446357786655426},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.41700878739356995},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4109799861907959},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37414801120758057},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3728347420692444},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34260159730911255},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18143054842948914},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.11900043487548828},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4612-2092-3_6","doi":"https://doi.org/10.1007/978-1-4612-2092-3_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-2092-3_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hormonal Carcinogenesis III","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W177339463","https://openalex.org/W1483922935","https://openalex.org/W1496591359","https://openalex.org/W1509664278","https://openalex.org/W1546134956","https://openalex.org/W1558788767","https://openalex.org/W1565505982","https://openalex.org/W1580828362","https://openalex.org/W1942745898","https://openalex.org/W1980106871","https://openalex.org/W1980223679","https://openalex.org/W2009759387","https://openalex.org/W2019738273","https://openalex.org/W2024986660","https://openalex.org/W2029058389","https://openalex.org/W2035765556","https://openalex.org/W2044438803","https://openalex.org/W2051369987","https://openalex.org/W2054605948","https://openalex.org/W2072964995","https://openalex.org/W2073315776","https://openalex.org/W2083625623","https://openalex.org/W2096337778","https://openalex.org/W2101299511","https://openalex.org/W2103970959","https://openalex.org/W2111885428","https://openalex.org/W2117762359","https://openalex.org/W2125537106","https://openalex.org/W2152605904","https://openalex.org/W2153579158","https://openalex.org/W2164459004","https://openalex.org/W2323655901","https://openalex.org/W2328105863","https://openalex.org/W2331585102"],"related_works":["https://openalex.org/W1992946317","https://openalex.org/W2044438803","https://openalex.org/W2029058389","https://openalex.org/W2097026108","https://openalex.org/W2302420556","https://openalex.org/W1971136490","https://openalex.org/W7099769151","https://openalex.org/W2000363271","https://openalex.org/W2095345972","https://openalex.org/W7099602782"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}