{"id":"https://openalex.org/W4106570","doi":null,"title":"Neurosyphilis masquerading as hemiparesis and Jacksonian epilepsy in an HIV positive patient: a case report.","display_name":"Neurosyphilis masquerading as hemiparesis and Jacksonian epilepsy in an HIV positive patient: a case report.","publication_year":2010,"publication_date":"2010-06-01","ids":{"openalex":"https://openalex.org/W4106570","mag":"4106570","pmid":"https://pubmed.ncbi.nlm.nih.gov/21326980","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2956285"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2956285","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2956285","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2956285","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038317735","display_name":"Peterson S Kyebambe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799916555","display_name":"Kabale Hospital","ror":"https://ror.org/03a470v04","country_code":"UG","type":"healthcare","lineage":["https://openalex.org/I2799916555"]}],"countries":["UG"],"is_corresponding":true,"raw_author_name":"P S Kyebambe","raw_affiliation_strings":["Department of Internal Medicine, Kabale Regional Referral Hospital, Uganda. kyebsteve@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Kabale Regional Referral Hospital, Uganda. kyebsteve@yahoo.com","institution_ids":["https://openalex.org/I2799916555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5038317735"],"corresponding_institution_ids":["https://openalex.org/I2799916555"],"apc_list":null,"apc_paid":null,"fwci":0.4183,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.63654983,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"10","issue":"2","first_page":"211","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12854","display_name":"Neurology and Historical Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurosyphilis","display_name":"neurosyphilis","score":1.0},{"id":"https://openalex.org/keywords/hiv-coinfection","display_name":"HIV coinfection","score":0.9010000228881836},{"id":"https://openalex.org/keywords/hemiparesis","display_name":"hemiparesis","score":0.9629999995231628},{"id":"https://openalex.org/keywords/jacksonian-epilepsy","display_name":"Jacksonian epilepsy","score":0.9909999966621399},{"id":"https://openalex.org/keywords/delirium","display_name":"delirium","score":0.7120000123977661},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-analysis","display_name":"cerebrospinal fluid analysis","score":0.7099999785423279},{"id":"https://openalex.org/keywords/vdrl-test","display_name":"VDRL test","score":0.7960000038146973},{"id":"https://openalex.org/keywords/treponema-pallidum","display_name":"Treponema pallidum","score":0.8109999895095825},{"id":"https://openalex.org/keywords/penicillin-g-therapy","display_name":"penicillin G therapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.38100001215934753}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9285997152328491},{"id":"https://openalex.org/C2781319584","wikidata":"https://www.wikidata.org/wiki/Q7888578","display_name":"Neurosyphilis","level":4,"score":0.9104369878768921},{"id":"https://openalex.org/C2776687281","wikidata":"https://www.wikidata.org/wiki/Q7294218","display_name":"Rapid plasma reagin","level":5,"score":0.6764320731163025},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.5895984172821045},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.527969479560852},{"id":"https://openalex.org/C174802600","wikidata":"https://www.wikidata.org/wiki/Q12190","display_name":"Penicillin","level":3,"score":0.491224467754364},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.45658060908317566},{"id":"https://openalex.org/C2778879792","wikidata":"https://www.wikidata.org/wiki/Q1126769","display_name":"Paresis","level":2,"score":0.42901769280433655},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33170658349990845},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.30270057916641235},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26391664147377014},{"id":"https://openalex.org/C2780187896","wikidata":"https://www.wikidata.org/wiki/Q134745","display_name":"Treponema","level":4,"score":0.23699772357940674},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.19394659996032715},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.14016202092170715},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.1387169361114502},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004318","descriptor_name":"Doxycycline","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009494","descriptor_name":"Neurosyphilis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010291","descriptor_name":"Paresis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010291","descriptor_name":"Paresis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010400","descriptor_name":"Penicillin G","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D013588","descriptor_name":"Syphilis Serodiagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2956285","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2956285","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},{"id":"pmid:21326980","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21326980","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"African health sciences","raw_type":"Case Reports"},{"id":"pmh:cria:bioline:hs:hs10041","doi":null,"is_oa":true,"landing_page_url":"http://www.bioline.org.br/abstract?id=hs10041","pdf_url":"http://www.bioline.org.br/abstract?id=hs10041","source":{"id":"https://openalex.org/S4306402188","display_name":"Bioline International (Bioline International)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"African Health Sciences (ISSN: 1680-6905) Vol 10 Num 2","raw_type":"CR"},{"id":"pmh:oai:utoronto.scholaris.ca:1807/50874","doi":null,"is_oa":true,"landing_page_url":"http://www.bioline.org.br/abstract?id=hs10041","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b22ecd7e-aed2-446a-9ff2-e35a08ce474c/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"mag:4106570","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21326980","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2956285","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2956285","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4106570.pdf","grobid_xml":"https://content.openalex.org/works/W4106570.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W4442096","https://openalex.org/W1975959601","https://openalex.org/W1985917775","https://openalex.org/W1990165995","https://openalex.org/W1998951476","https://openalex.org/W2029573477","https://openalex.org/W2030761577","https://openalex.org/W2048452399","https://openalex.org/W2057981208","https://openalex.org/W2069132905","https://openalex.org/W2069646201","https://openalex.org/W2075930231","https://openalex.org/W2081841128","https://openalex.org/W2084213492","https://openalex.org/W2092450746","https://openalex.org/W2095280747","https://openalex.org/W2101485588","https://openalex.org/W2109168052","https://openalex.org/W2120399421","https://openalex.org/W2142496702","https://openalex.org/W2143007139","https://openalex.org/W2151526426","https://openalex.org/W2414794478","https://openalex.org/W2417403750","https://openalex.org/W2418920666","https://openalex.org/W2436749587","https://openalex.org/W2595489081"],"related_works":["https://openalex.org/W6992941796","https://openalex.org/W2744719745","https://openalex.org/W2591039510","https://openalex.org/W4233986611","https://openalex.org/W3183975444","https://openalex.org/W2079728017","https://openalex.org/W2132523206","https://openalex.org/W2029573477","https://openalex.org/W2002310731","https://openalex.org/W2323588299"],"abstract_inverted_index":{"BACKGROUND:":[0],"Neurosyphilis":[1,189],"is":[2,21],"a":[3,82,111,184],"common":[4],"but":[5],"often":[6,22,36],"missed":[7,23],"disease":[8],"worldwide,":[9],"mainly":[10],"because":[11],"it":[12],"has":[13],"many":[14],"manifestations":[15],"making":[16],"its":[17,38],"diagnosis":[18,65],"difficult.":[19],"It":[20,194],"among":[24],"HIV":[25,76],"patients":[26,200],"as":[27,34],"the":[28,54,69,157],"search":[29],"for":[30,180],"other":[31],"co-infections":[32],"such":[33],"toxoplasmosis":[35],"overshadows":[37],"consideration.":[39],"OBJECTIVES:":[40],"To":[41],"describe":[42],"one":[43],"of":[44,47,56,68,86],"our":[45,62],"cases":[46,209],"neurosyphilis":[48,57],"in":[49,58,64,192,198],"HIV,":[50],"raise":[51],"awareness":[52],"about":[53],"reality":[55],"Africa":[59],"and":[60,66,90,97,103,114],"share":[61],"experiences":[63],"management":[67],"disease.":[70],"METHODS:":[71],"A":[72],"40":[73],"year":[74],"old,":[75],"positive":[77],"female":[78],"was":[79,121,128,159,165,170],"admitted":[80],"with":[81,172,183,201,206],"2":[83],"month":[84],"history":[85],"left":[87,115],"sided":[88,116],"facial":[89],"limb":[91],"weakness":[92],"followed":[93],"by":[94],"delirium,":[95],"aphasia":[96],"Jacksonian":[98],"epilepsy.":[99],"She":[100,169],"underwent":[101],"clinical":[102],"laboratory":[104],"evaluation.":[105],"RESULTS:":[106],"On":[107],"examination":[108],"she":[109],"had":[110],"maculo-papular":[112],"rash":[113],"paresis.":[117],"Rapid":[118],"Plasma":[119],"Reagin(RPR)":[120],"reactive(titre":[122],"1:16).":[123],"Treponema":[124],"Pallidum":[125],"Haemoaggluttination":[126],"Assay(TPHA)":[127],"also":[129],"reactive.":[130],"Cerebrospinal":[131],"fluid":[132],"(CSF)":[133],"analysis":[134],"revealed:":[135],"protein":[136],"56":[137],"mg":[138,143],"per":[139,144,148,167],"dl,":[140,145],"glucose":[141],"71":[142],"cells":[146],"14":[147,181],"high":[149],"power":[150],"field":[151],"(predominantly":[152],"lymphocytes).":[153],"The":[154,161],"VDRL":[155],"on":[156],"CSF":[158],"positive.":[160],"CD4":[162],"cell":[163],"count":[164],"320":[166],"ml.":[168],"treated":[171],"intravenous":[173,213],"penicillin":[174,214],"G,":[175],"4":[176],"mega-units":[177],"6":[178],"hourly":[179],"days,":[182],"very":[185],"good":[186],"response.":[187],"CONCLUSION:":[188],"still":[190],"occurs":[191],"Uganda.":[193],"should":[195],"be":[196],"considered":[197],"all":[199],"neurological/ophthalmic":[202],"illness,":[203],"including":[204],"those":[205],"HIV.":[207],"Most":[208],"respond":[210],"well":[211],"to":[212],"G.":[215]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}