{"id":"https://openalex.org/W40918988","doi":"https://doi.org/10.1007/128_2014_551","title":"Biomolecular Halogen Bonds","display_name":"Biomolecular Halogen Bonds","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W40918988","doi":"https://doi.org/10.1007/128_2014_551","mag":"40918988","pmid":"https://pubmed.ncbi.nlm.nih.gov/25326832"},"language":"en","primary_location":{"id":"doi:10.1007/128_2014_551","doi":"https://doi.org/10.1007/128_2014_551","is_oa":false,"landing_page_url":"https://doi.org/10.1007/128_2014_551","pdf_url":null,"source":{"id":"https://openalex.org/S4210194882","display_name":"Topics in current chemistry","issn_l":"0340-1022","issn":["0340-1022","1436-5049"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Topics in Current Chemistry","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2484397388","display_name":"Halogen Bonding I"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069937373","display_name":"Pui Shing Ho","orcid":"https://orcid.org/0000-0002-8082-4311","observed_orcids":["https://orcid.org/0000-0002-8082-4311"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"P. Shing Ho","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523-1870, USA, shing.ho@colostate.edu","Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523-1870, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523-1870, USA, shing.ho@colostate.edu","institution_ids":["https://openalex.org/I92446798"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523-1870, USA","institution_ids":["https://openalex.org/I92446798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5069937373"],"corresponding_institution_ids":["https://openalex.org/I92446798"],"apc_list":null,"apc_paid":null,"fwci":13.9453,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.98035363,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"358","issue":null,"first_page":"241","last_page":"276"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/halogen-bonding","display_name":"halogen bonding","score":0.8190000057220459},{"id":"https://openalex.org/keywords/structure-energy-relationship","display_name":"structure-energy relationship","score":0.6930000185966492},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.5839999914169312},{"id":"https://openalex.org/keywords/protein-ligand-interactions","display_name":"protein-ligand interactions","score":0.8059999942779541},{"id":"https://openalex.org/keywords/nucleic-acid-binding","display_name":"nucleic acid binding","score":0.6449999809265137},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.7760000228881836},{"id":"https://openalex.org/keywords/inhibitor-design","display_name":"inhibitor design","score":0.6660000085830688},{"id":"https://openalex.org/keywords/rational-drug-design","display_name":"rational drug design","score":0.9179999828338623},{"id":"https://openalex.org/keywords/biological-materials","display_name":"biological materials","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8440619707107544},{"id":"https://openalex.org/C23029723","wikidata":"https://www.wikidata.org/wiki/Q1193318","display_name":"Halogen bond","level":4,"score":0.7470213174819946},{"id":"https://openalex.org/C46062151","wikidata":"https://www.wikidata.org/wiki/Q19605","display_name":"Halogen","level":3,"score":0.7086372971534729},{"id":"https://openalex.org/C53105671","wikidata":"https://www.wikidata.org/wiki/Q14777816","display_name":"Rational design","level":2,"score":0.5968572497367859},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.5584229230880737},{"id":"https://openalex.org/C161624437","wikidata":"https://www.wikidata.org/wiki/Q1988322","display_name":"Small molecule","level":2,"score":0.47023719549179077},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.46358203887939453},{"id":"https://openalex.org/C192071366","wikidata":"https://www.wikidata.org/wiki/Q2991682","display_name":"Drug design","level":2,"score":0.4535920321941376},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.445894718170166},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.42010629177093506},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.3962878882884979},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3828611373901367},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.3393844664096832},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.15592166781425476},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1429460048675537},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002616","descriptor_name":"Chemical Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002616","descriptor_name":"Chemical Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002616","descriptor_name":"Chemical Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006219","descriptor_name":"Halogens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/128_2014_551","doi":"https://doi.org/10.1007/128_2014_551","is_oa":false,"landing_page_url":"https://doi.org/10.1007/128_2014_551","pdf_url":null,"source":{"id":"https://openalex.org/S4210194882","display_name":"Topics in current chemistry","issn_l":"0340-1022","issn":["0340-1022","1436-5049"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Topics in Current Chemistry","raw_type":"book-chapter"},{"id":"pmid:25326832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25326832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Topics in current chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.5699999928474426,"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309627","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17"},{"id":"https://openalex.org/F4320312210","display_name":"Fulbright Association","ror":"https://ror.org/00300j256"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":132,"referenced_works":["https://openalex.org/W1509343435","https://openalex.org/W1513508587","https://openalex.org/W1548914255","https://openalex.org/W1637465330","https://openalex.org/W1921843724","https://openalex.org/W1964004579","https://openalex.org/W1965146789","https://openalex.org/W1968255354","https://openalex.org/W1970197743","https://openalex.org/W1971892655","https://openalex.org/W1974783209","https://openalex.org/W1976161355","https://openalex.org/W1976254260","https://openalex.org/W1977021635","https://openalex.org/W1978809115","https://openalex.org/W1985274607","https://openalex.org/W1990779594","https://openalex.org/W1991964259","https://openalex.org/W1992525635","https://openalex.org/W1993496775","https://openalex.org/W1998948060","https://openalex.org/W1999798503","https://openalex.org/W2000753651","https://openalex.org/W2001299609","https://openalex.org/W2003858378","https://openalex.org/W2007764378","https://openalex.org/W2015377543","https://openalex.org/W2018107830","https://openalex.org/W2018398804","https://openalex.org/W2020734518","https://openalex.org/W2023578884","https://openalex.org/W2023629397","https://openalex.org/W2023801833","https://openalex.org/W2026106662","https://openalex.org/W2026598007","https://openalex.org/W2027392184","https://openalex.org/W2028257320","https://openalex.org/W2031227040","https://openalex.org/W2031962477","https://openalex.org/W2032456809","https://openalex.org/W2033127028","https://openalex.org/W2034903056","https://openalex.org/W2039316467","https://openalex.org/W2040569586","https://openalex.org/W2041302869","https://openalex.org/W2045373355","https://openalex.org/W2046604326","https://openalex.org/W2050088996","https://openalex.org/W2051828492","https://openalex.org/W2053499564","https://openalex.org/W2053855512","https://openalex.org/W2054975178","https://openalex.org/W2056426681","https://openalex.org/W2059107251","https://openalex.org/W2062236268","https://openalex.org/W2062323422","https://openalex.org/W2063092901","https://openalex.org/W2063200470","https://openalex.org/W2063779505","https://openalex.org/W2063788842","https://openalex.org/W2065485112","https://openalex.org/W2067455153","https://openalex.org/W2069931511","https://openalex.org/W2070519837","https://openalex.org/W2070914359","https://openalex.org/W2071180837","https://openalex.org/W2071836755","https://openalex.org/W2074947906","https://openalex.org/W2079200042","https://openalex.org/W2082640268","https://openalex.org/W2083752746","https://openalex.org/W2084611277","https://openalex.org/W2089168489","https://openalex.org/W2089483927","https://openalex.org/W2092522316","https://openalex.org/W2094294679","https://openalex.org/W2094742663","https://openalex.org/W2098305412","https://openalex.org/W2098587560","https://openalex.org/W2098589989","https://openalex.org/W2104457651","https://openalex.org/W2105058945","https://openalex.org/W2106466007","https://openalex.org/W2108750191","https://openalex.org/W2110310588","https://openalex.org/W2115121744","https://openalex.org/W2115561143","https://openalex.org/W2118233996","https://openalex.org/W2121372252","https://openalex.org/W2121996197","https://openalex.org/W2123126934","https://openalex.org/W2126961173","https://openalex.org/W2129486793","https://openalex.org/W2130479394","https://openalex.org/W2131214655","https://openalex.org/W2131239401","https://openalex.org/W2131754023","https://openalex.org/W2134880599","https://openalex.org/W2136639243","https://openalex.org/W2140074237","https://openalex.org/W2148363990","https://openalex.org/W2148602202","https://openalex.org/W2149129664","https://openalex.org/W2149658883","https://openalex.org/W2152503709","https://openalex.org/W2153524217","https://openalex.org/W2157680389","https://openalex.org/W2159356452","https://openalex.org/W2160842779","https://openalex.org/W2165371679","https://openalex.org/W2166344128","https://openalex.org/W2166845515","https://openalex.org/W2166976731","https://openalex.org/W2170170098","https://openalex.org/W2170891294","https://openalex.org/W2315836975","https://openalex.org/W2317057295","https://openalex.org/W2319057313","https://openalex.org/W2322081414","https://openalex.org/W2323190074","https://openalex.org/W2323201107","https://openalex.org/W2323510144","https://openalex.org/W2324777999","https://openalex.org/W2329413911","https://openalex.org/W2333083696","https://openalex.org/W2397460362","https://openalex.org/W2420197552","https://openalex.org/W2528469474","https://openalex.org/W2886747822","https://openalex.org/W2912890680","https://openalex.org/W2951191884","https://openalex.org/W4240703037"],"related_works":["https://openalex.org/W2059107251","https://openalex.org/W2603653402","https://openalex.org/W2332719959","https://openalex.org/W2278977157","https://openalex.org/W2739631729","https://openalex.org/W2166845515","https://openalex.org/W2895685440","https://openalex.org/W2598562732","https://openalex.org/W2041302869","https://openalex.org/W3156042852"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}