{"id":"https://openalex.org/W40619696","doi":"https://doi.org/10.1007/978-3-7643-7520-1_8","title":"Nanotechnology: Towards the detection and treatment of inflammatory diseases","display_name":"Nanotechnology: Towards the detection and treatment of inflammatory diseases","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W40619696","doi":"https://doi.org/10.1007/978-3-7643-7520-1_8","mag":"40619696"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-7643-7520-1_8","doi":"https://doi.org/10.1007/978-3-7643-7520-1_8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-7643-7520-1_8","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-7643-7520-1_8.pdf","source":{"id":"https://openalex.org/S4306462920","display_name":"Birkh\u00e4user Basel eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Vivo Models of Inflammation","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4241123069","display_name":"In Vivo Models of Inflammation"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/978-3-7643-7520-1_8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111494549","display_name":"Sreekant Murthy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sreekant Murthy","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Drexel University College of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Drexel University College of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109563584","display_name":"Elisabeth S. Papazoglou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elisabeth Papazoglou","raw_affiliation_strings":["School of Biomedical Engineering, Drexel University, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Drexel University, Philadelphia, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023826581","display_name":"Nandhakumar Kanagarajan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nandhakumar Kanagarajan","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Drexel University College of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Drexel University College of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109530916","display_name":"Narasim S. Murthy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160893","display_name":"Associated Radiologists","ror":"https://ror.org/05tt6ka81","country_code":"US","type":"other","lineage":["https://openalex.org/I4210160893"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Narasim S. Murthy","raw_affiliation_strings":["Associated Radiologists, PA, 322 E. Antietam Street, Suite 106, Hagerstown, MD, 21740, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associated Radiologists, PA, 322 E. Antietam Street, Suite 106, Hagerstown, MD, 21740, USA","institution_ids":["https://openalex.org/I4210160893"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.01484399,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"155","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14089","display_name":"Nanotechnology research and applications","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14089","display_name":"Nanotechnology research and applications","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.9440000057220459},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"nanotechnology","score":0.7570000290870667},{"id":"https://openalex.org/keywords/inflammatory-diseases","display_name":"inflammatory diseases","score":0.9869999885559082},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.9340000152587891},{"id":"https://openalex.org/keywords/tissue-engineering-scaffolds","display_name":"tissue engineering scaffolds","score":0.8460000157356262},{"id":"https://openalex.org/keywords/biomedical-implants","display_name":"biomedical implants","score":0.8529999852180481},{"id":"https://openalex.org/keywords/nanorobotics","display_name":"nanorobotics","score":0.968999981880188},{"id":"https://openalex.org/keywords/drug-screening","display_name":"drug screening","score":0.9409999847412109},{"id":"https://openalex.org/keywords/diagnostic-imaging","display_name":"diagnostic imaging","score":0.8040000200271606},{"id":"https://openalex.org/keywords/regulatory-challenges","display_name":"regulatory challenges","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.7294070720672607},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.639549195766449},{"id":"https://openalex.org/C187911381","wikidata":"https://www.wikidata.org/wiki/Q587024","display_name":"Nanorobotics","level":2,"score":0.6227595806121826},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.500070333480835},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4846949875354767},{"id":"https://openalex.org/C59411770","wikidata":"https://www.wikidata.org/wiki/Q8242560","display_name":"Biological warfare","level":2,"score":0.41154199838638306},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.4046386480331421},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35640424489974976},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.15615388751029968},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.12295886874198914},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-7643-7520-1_8","doi":"https://doi.org/10.1007/978-3-7643-7520-1_8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-7643-7520-1_8","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-7643-7520-1_8.pdf","source":{"id":"https://openalex.org/S4306462920","display_name":"Birkh\u00e4user Basel eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Vivo Models of Inflammation","raw_type":"book-chapter"},{"id":"pmh:oai:pubmedcentral.nih.gov:7147450","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7147450","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Vivo Models of Inflammation","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/978-3-7643-7520-1_8","doi":"https://doi.org/10.1007/978-3-7643-7520-1_8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-7643-7520-1_8","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-7643-7520-1_8.pdf","source":{"id":"https://openalex.org/S4306462920","display_name":"Birkh\u00e4user Basel eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Vivo Models of Inflammation","raw_type":"book-chapter"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W40619696.pdf","grobid_xml":"https://content.openalex.org/works/W40619696.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W46925008","https://openalex.org/W1481296411","https://openalex.org/W1510613202","https://openalex.org/W1548443253","https://openalex.org/W1549038188","https://openalex.org/W1561712812","https://openalex.org/W1592496574","https://openalex.org/W1853499144","https://openalex.org/W1867238542","https://openalex.org/W1964116607","https://openalex.org/W1964357188","https://openalex.org/W1976632699","https://openalex.org/W1977793874","https://openalex.org/W1980695842","https://openalex.org/W1982436786","https://openalex.org/W1985900564","https://openalex.org/W1992803165","https://openalex.org/W1995337879","https://openalex.org/W2001018320","https://openalex.org/W2005272031","https://openalex.org/W2007310248","https://openalex.org/W2015744890","https://openalex.org/W2018470991","https://openalex.org/W2027688466","https://openalex.org/W2027691472","https://openalex.org/W2031358898","https://openalex.org/W2041008239","https://openalex.org/W2043009832","https://openalex.org/W2044504861","https://openalex.org/W2053192345","https://openalex.org/W2059875487","https://openalex.org/W2061510929","https://openalex.org/W2066986283","https://openalex.org/W2069111085","https://openalex.org/W2069601286","https://openalex.org/W2070088962","https://openalex.org/W2070897329","https://openalex.org/W2072589359","https://openalex.org/W2074954932","https://openalex.org/W2084196088","https://openalex.org/W2089117567","https://openalex.org/W2089951589","https://openalex.org/W2095248480","https://openalex.org/W2095833985","https://openalex.org/W2096593771","https://openalex.org/W2100553609","https://openalex.org/W2105091837","https://openalex.org/W2106955414","https://openalex.org/W2110111661","https://openalex.org/W2111115146","https://openalex.org/W2111357501","https://openalex.org/W2111970355","https://openalex.org/W2112101570","https://openalex.org/W2115625402","https://openalex.org/W2115907801","https://openalex.org/W2116810900","https://openalex.org/W2117215118","https://openalex.org/W2117673080","https://openalex.org/W2120197576","https://openalex.org/W2121945369","https://openalex.org/W2126036130","https://openalex.org/W2129445703","https://openalex.org/W2130871581","https://openalex.org/W2131145865","https://openalex.org/W2132976817","https://openalex.org/W2135881279","https://openalex.org/W2136132417","https://openalex.org/W2140611255","https://openalex.org/W2142639973","https://openalex.org/W2143978130","https://openalex.org/W2147585883","https://openalex.org/W2148726864","https://openalex.org/W2148924929","https://openalex.org/W2153314924","https://openalex.org/W2154010412","https://openalex.org/W2154321074","https://openalex.org/W2154451349","https://openalex.org/W2158563837","https://openalex.org/W2160564412","https://openalex.org/W2171271556","https://openalex.org/W2171338310","https://openalex.org/W2172005133","https://openalex.org/W2316730265","https://openalex.org/W2317257687","https://openalex.org/W2400850597","https://openalex.org/W2422756294","https://openalex.org/W2822822418","https://openalex.org/W3020859884","https://openalex.org/W4241794178"],"related_works":["https://openalex.org/W2938881252","https://openalex.org/W4394730021","https://openalex.org/W3081080378","https://openalex.org/W4293172785","https://openalex.org/W6949492701","https://openalex.org/W1996514798","https://openalex.org/W2167135384","https://openalex.org/W7155205777","https://openalex.org/W3140453494","https://openalex.org/W2621307476"],"abstract_inverted_index":{"Biological":[0],"systems":[1,17],"operate":[2],"at":[3,32],"the":[4,8,33,39,56,68,126,133,137,162,179,186],"nanoscale.":[5],"Nanomedicine":[6],"is":[7,23,169],"application":[9],"of":[10,29,60,70,164,181,185,188],"nanotechnology":[11],"to":[12,67,83,87,128,135,142,147,174],"monitor":[13],"and":[14,20,35,58,76,104,112,122,145,158,172,183],"treat":[15],"biological":[16,75],"in":[18,47,51,54,161],"health":[19],"disease.":[21],"This":[22],"accomplished":[24],"by":[25,120],"real":[26],"time":[27],"monitoring":[28],"molecular":[30],"signaling":[31],"cellular":[34],"tissue":[36,97],"level.":[37],"During":[38],"past":[40],"decade,":[41],"there":[42,152,168],"has":[43,80],"been":[44,81],"an":[45],"explosion":[46],"this":[48],"field,":[49],"resulting":[50],"revolutionary":[52],"advances":[53],"determining":[55],"microstructure":[57],"function":[59],"living":[61],"systems.":[62],"These":[63],"discoveries":[64],"have":[65],"led":[66],"development":[69],"powerful":[71],"tools":[72,141],"for":[73,96,178],"fundamental":[74],"medical":[77,113],"research.":[78],"Nanotechnology":[79],"applied":[82],"targeted":[84],"drug":[85,110],"delivery":[86],"minimize":[88],"side":[89],"effects,":[90],"creating":[91,99],"implantable":[92,100],"materials":[93],"as":[94,106,108],"scaffolds":[95],"engineering,":[98],"devices,":[101],"surgical":[102],"aids":[103],"nanorobotics,":[105],"well":[107],"throughput":[109],"screening":[111],"diagnostic":[114],"imaging.":[115],"The":[116],"nanoinitiatives":[117],"are":[118],"funded":[119],"governments":[121],"private":[123],"sources":[124],"throughout":[125],"world":[127],"develop":[129],"or":[130],"further":[131],"refine":[132],"technology":[134],"provide":[136],"beyond-imaginable,":[138],"most":[139],"sophisticated":[140],"a":[143],"physician":[144],"scientists":[146],"inflammatory":[148],"diseases.":[149],"No":[150],"doubt,":[151],"will":[153],"be":[154],"many":[155],"technical,":[156],"regulatory":[157],"legal":[159],"challenges":[160,177],"deployment":[163],"these":[165,176],"technologies.":[166],"Unquestionably,":[167],"enough":[170],"desire":[171],"commitment":[173],"meet":[175],"good":[180],"society":[182],"betterment":[184],"quality":[187],"life.":[189]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}