{"id":"https://openalex.org/W40539014","doi":null,"title":"Analgesia, sedation and neuromuscular blockade in mechanically ventilated cardiac intensive care unit patients. Part III--Neuromuscular blockade.","display_name":"Analgesia, sedation and neuromuscular blockade in mechanically ventilated cardiac intensive care unit patients. Part III--Neuromuscular blockade.","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W40539014","mag":"40539014","pmid":"https://pubmed.ncbi.nlm.nih.gov/16789407"},"language":"en","primary_location":{"id":"pmid:16789407","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16789407","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109252099","display_name":"H. Vilela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099144","display_name":"Hospital Prof. Dr. Fernando Fonseca","ror":"https://ror.org/010bsbc18","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210099144"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Hugo Vilela","raw_affiliation_strings":["Servi\u00e7o de Cardiologia, Hospital Fernando Fonseca, Amadora, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servi\u00e7o de Cardiologia, Hospital Fernando Fonseca, Amadora, Portugal","institution_ids":["https://openalex.org/I4210099144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078184497","display_name":"Daniel Ferreira","orcid":"https://orcid.org/0000-0002-4683-0179","observed_orcids":["https://orcid.org/0000-0002-4683-0179"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Ferreira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0062028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"3","first_page":"341","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.10459999740123749,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromuscular-blockade","display_name":"neuromuscular blockade","score":0.9919999837875366},{"id":"https://openalex.org/keywords/sedation","display_name":"sedation","score":0.7300000190734863},{"id":"https://openalex.org/keywords/pain-relief","display_name":"analgesia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"mechanical ventilation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cardiac-intensive-care","display_name":"cardiac intensive care","score":0.8820000290870667},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.6660000085830688},{"id":"https://openalex.org/keywords/pain","display_name":"pain","score":0.46799999475479126},{"id":"https://openalex.org/keywords/agitation","display_name":"agitation","score":0.8610000014305115},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.949999988079071},{"id":"https://openalex.org/keywords/delirium","display_name":"delirium","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neuromuscular-blocking-agents","display_name":"neuromuscular blocking agents","score":0.878000020980835},{"id":"https://openalex.org/keywords/sedation-monitoring","display_name":"sedation monitoring","score":0.6909999847412109},{"id":"https://openalex.org/keywords/sedation-regimens","display_name":"sedation protocols","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C2776814716","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Sedation","level":2,"score":0.8997542858123779},{"id":"https://openalex.org/C2909465803","wikidata":"https://www.wikidata.org/wiki/Q3286619","display_name":"Neuromuscular Blockade","level":2,"score":0.8409334421157837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7999550104141235},{"id":"https://openalex.org/C2779753318","wikidata":"https://www.wikidata.org/wiki/Q160796","display_name":"Delirium","level":2,"score":0.7786767482757568},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.6466535329818726},{"id":"https://openalex.org/C2910841738","wikidata":"https://www.wikidata.org/wiki/Q3286619","display_name":"Neuromuscular Blocking Agents","level":2,"score":0.6134973168373108},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5895825028419495},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.4658459424972534},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.40987667441368103},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07220432162284851},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000698","descriptor_name":"Analgesia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002309","descriptor_name":"Cardiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009466","descriptor_name":"Neuromuscular Blocking Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012121","descriptor_name":"Respiration, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016292","descriptor_name":"Procedural Sedation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019148","descriptor_name":"Neuromuscular Blockade","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:16789407","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16789407","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2154002618","https://openalex.org/W2017261343","https://openalex.org/W6989213339","https://openalex.org/W7054816260","https://openalex.org/W2073118250","https://openalex.org/W2192762463","https://openalex.org/W4248882157","https://openalex.org/W2043385537","https://openalex.org/W2409071777","https://openalex.org/W2325057847"],"abstract_inverted_index":{"This":[0],"article":[1],"reviews":[2],"relevant":[3],"clinical":[4,62],"issues":[5],"regarding":[6],"sedation,":[7,44,110],"analgesia":[8,45,111],"and":[9,21,32,46,69,112],"neuromuscular":[10,47,113],"blockade":[11],"in":[12,34,50,61,89],"the":[13,35,67,90,107],"cardiac":[14],"intensive":[15],"care":[16,52],"unit,":[17],"including":[18],"monitoring":[19,102],"tools":[20],"available":[22],"therapeutic":[23,79],"options.":[24],"The":[25,64],"pathophysiologic":[26],"implications":[27],"of":[28,66,82,92,109],"pain,":[29],"agitation,":[30],"anxiety":[31],"delirium":[33],"ventilated":[36],"patient":[37],"are":[38,104],"also":[39],"discussed.":[40],"Although":[41],"guidelines":[42],"for":[43,106],"blocking":[48],"drugs":[49],"critical":[51],"have":[53],"recently":[54],"been":[55],"published,":[56],"there":[57],"is":[58,85],"great":[59],"variability":[60],"practice.":[63],"complexity":[65],"environment":[68],"associated":[70],"pathologies":[71],"makes":[72],"it":[73],"difficult":[74],"to":[75,96],"implement":[76],"universally":[77],"applicable":[78],"regimens.":[80],"Knowledge":[81],"pharmacologic":[83],"mechanisms":[84],"an":[86],"important":[87],"tool":[88],"development":[91],"dynamic":[93],"protocols":[94],"adapted":[95],"each":[97],"unit.":[98],"Strategies":[99],"that":[100],"include":[101],"resources":[103],"essential":[105],"optimization":[108],"blockade.":[114]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}