{"id":"https://openalex.org/W40161448","doi":null,"title":"Fetal compensatory responses to reduced oxygen delivery.","display_name":"Fetal compensatory responses to reduced oxygen delivery.","publication_year":1984,"publication_date":"1984-07-01","ids":{"openalex":"https://openalex.org/W40161448","mag":"40161448","pmid":"https://pubmed.ncbi.nlm.nih.gov/6740334"},"language":"en","primary_location":{"id":"pmid:6740334","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6740334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in perinatology","raw_type":"Journal Article"},"parent_works":[],"lineage":["https://openalex.org/W40161448"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048837572","display_name":"Daniel I. Edelstone","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"D I Edelstone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5048837572"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.525,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.77393484,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"8","issue":"3","first_page":"184","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.5770999789237976,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.5770999789237976,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.35030001401901245,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.029899999499320984,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fetal-oxygen-delivery","display_name":"fetal oxygen delivery","score":0.8679999709129333},{"id":"https://openalex.org/keywords/fetal-hypoxemia","display_name":"fetal hypoxemia","score":0.8370000123977661},{"id":"https://openalex.org/keywords/compensatory-mechanisms","display_name":"compensatory mechanisms","score":0.5889999866485596},{"id":"https://openalex.org/keywords/tissue-hypoxia","display_name":"tissue hypoxia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/lactic-acidosis","display_name":"lactic acidosis","score":0.9750000238418579},{"id":"https://openalex.org/keywords/fetal-oxygenation","display_name":"fetal oxygenation","score":0.6949999928474426},{"id":"https://openalex.org/keywords/fetal-metabolism","display_name":"fetal metabolism","score":0.39500001072883606}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.8578858375549316},{"id":"https://openalex.org/C2776779939","wikidata":"https://www.wikidata.org/wiki/Q1479485","display_name":"Hypoxemia","level":2,"score":0.7333136796951294},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6972662210464478},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6002263426780701},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5689963698387146},{"id":"https://openalex.org/C70289976","wikidata":"https://www.wikidata.org/wiki/Q17143603","display_name":"Oxygenation","level":2,"score":0.43452784419059753},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36243772506713867},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3487185835838318},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.29820168018341064},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1891878843307495},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.12532609701156616},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005311","descriptor_name":"Fetal Hypoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005318","descriptor_name":"Fetal Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007022","descriptor_name":"Hypotension","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011249","descriptor_name":"Pregnancy Complications, Cardiovascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014470","descriptor_name":"Umbilical Cord","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014472","descriptor_name":"Umbilicus","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:6740334","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6740334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in perinatology","raw_type":"Journal Article"},{"id":"mag:40161448","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6740334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W117355859","https://openalex.org/W165167765","https://openalex.org/W180468576","https://openalex.org/W1503566707","https://openalex.org/W1511510283","https://openalex.org/W1574956616","https://openalex.org/W1591484147","https://openalex.org/W1621252571","https://openalex.org/W1835478391","https://openalex.org/W1943296211","https://openalex.org/W1966609305","https://openalex.org/W1974713257","https://openalex.org/W2002845071","https://openalex.org/W2063986174","https://openalex.org/W2070308061","https://openalex.org/W2111474757","https://openalex.org/W2111681776","https://openalex.org/W2177425329","https://openalex.org/W2193177257","https://openalex.org/W2220874392","https://openalex.org/W2345524566","https://openalex.org/W2395400019","https://openalex.org/W2402117508","https://openalex.org/W2404073958","https://openalex.org/W2409935144","https://openalex.org/W2411065284","https://openalex.org/W2411955202","https://openalex.org/W2416808804","https://openalex.org/W2420393484","https://openalex.org/W2421726884","https://openalex.org/W2426244986","https://openalex.org/W2431285535","https://openalex.org/W2433490251","https://openalex.org/W2472401467","https://openalex.org/W2473900382"],"related_works":["https://openalex.org/W2279373206","https://openalex.org/W2263876433","https://openalex.org/W1998038248","https://openalex.org/W2443472280","https://openalex.org/W2248871291","https://openalex.org/W2019314243","https://openalex.org/W2414749041","https://openalex.org/W2035950918","https://openalex.org/W2085651222","https://openalex.org/W1891867004"],"abstract_inverted_index":{"I":[0],"have":[1],"described":[2],"how":[3],"various":[4],"maternal":[5],"and":[6,87,125],"fetal":[7,11,25,34,42,48,56,68,190],"conditions":[8],"can":[9,28,115,126],"affect":[10],"oxygen":[12,43,105,113,123,141],"delivery.":[13],"It":[14],"is":[15,58,93,98,182],"clear":[16],"from":[17],"much":[18],"of":[19,37,79,101,104,133,150,164,186,189],"the":[20,76,102,147,168,172,183,187],"recent":[21],"experimental":[22],"evidence":[23],"that":[24,175],"oxidative":[26,128],"metabolism":[27,129],"be":[29,71,82,177],"sustained":[30],"despite":[31],"reductions":[32],"in":[33,65,121,160],"O2":[35,61,151,165,180],"delivery":[36],"40-50%.":[38],"As":[39,60],"long":[40],"as":[41],"reserves":[44,62,142],"are":[45,63],"not":[46,97,144],"depleted,":[47],"metabolic":[49],"functions":[50],"will":[51,70,81,143],"continue":[52],"aerobically,":[53],"even":[54,146,158],"though":[55],"hypoxemia":[57,69],"present.":[59],"exhausted":[64],"some":[66],"tissues,":[67],"associated":[72],"with":[73,110,139],"tissue":[74,88,155],"hypoxia,":[75],"net":[77],"result":[78],"which":[80],"anaerobic":[83],"metabolism,":[84],"lactic":[85],"acidosis,":[86],"death.":[89],"Whether":[90],"a":[91,99,111,131,137],"fetus":[92,109,138],"adequately":[94],"oxygenated":[95],"or":[96,157],"function":[100],"quantity":[103,163],"reserve":[106,114],"available.":[107],"A":[108],"substantial":[112],"compensate":[116],"fully":[117],"for":[118],"most":[119],"interferences":[120],"its":[122],"supply":[124],"maintain":[127],"under":[130],"variety":[132],"conditions.":[134],"In":[135],"contrast,":[136],"minimal":[140],"tolerate":[145],"mildest":[148],"degree":[149],"deficiency":[152],"without":[153],"developing":[154],"hypoxia":[156],"death":[159],"utero.":[161],"The":[162],"delivered":[166],"to":[167],"fetus,":[169],"rather":[170],"than":[171],"specific":[173],"condition":[174],"may":[176],"adversely":[178],"affecting":[179],"delivery,":[181],"important":[184],"determinant":[185],"adequacy":[188],"oxygenation.":[191]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}