{"id":"https://openalex.org/W392363451","doi":null,"title":"Biological properties evaluation and chemical profiles of phenolic compounds in muscadine grapes (Vitis rotundifolia)","display_name":"Biological properties evaluation and chemical profiles of phenolic compounds in muscadine grapes (Vitis rotundifolia)","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W392363451","mag":"392363451"},"language":"en","primary_location":{"id":"pmh:oai:open.clemson.edu:all_dissertations-1902","doi":null,"is_oa":false,"landing_page_url":"https://open.clemson.edu/all_dissertations/902","pdf_url":null,"source":{"id":"https://openalex.org/S4377196397","display_name":"TigerPrints (Clemson University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I8078737","host_organization_name":"Clemson University","host_organization_lineage":["https://openalex.org/I8078737"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"All Dissertations","raw_type":"text"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103776318","display_name":"Qi You","orcid":"https://orcid.org/0009-0009-3449-3134","observed_orcids":["https://orcid.org/0009-0009-3449-3134"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Qi You","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-3449-3134","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5103776318"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11796","display_name":"Horticultural and Viticultural Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/muscadine-grape","display_name":"muscadine grape","score":0.8889999985694885},{"id":"https://openalex.org/keywords/vitis-rotundifolia","display_name":"Vitis rotundifolia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.9490000009536743},{"id":"https://openalex.org/keywords/anthocyanins","display_name":"anthocyanins","score":1.0},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.875},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/alpha-glucosidase-inhibition","display_name":"\u03b1-glucosidase inhibition","score":0.9649999737739563},{"id":"https://openalex.org/keywords/alpha-amylase-inhibition","display_name":"\u03b1-amylase inhibition","score":0.9760000109672546},{"id":"https://openalex.org/keywords/pancreatic-lipase-inhibition","display_name":"pancreatic lipase inhibition","score":0.9660000205039978},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8889999985694885},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7879999876022339},{"id":"https://openalex.org/keywords/hplc-elsd","display_name":"HPLC-ELSD","score":0.7879999876022339},{"id":"https://openalex.org/keywords/hplc-uv-ms","display_name":"HPLC-UV-MS","score":0.8700000047683716},{"id":"https://openalex.org/keywords/phenolic-acids","display_name":"phenolic acids","score":0.5580000281333923},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9819999933242798}],"concepts":[{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.46431681513786316},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41435396671295166},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3871593773365021},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.32967618107795715},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.32636621594429016}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:open.clemson.edu:all_dissertations-1902","doi":null,"is_oa":false,"landing_page_url":"https://open.clemson.edu/all_dissertations/902","pdf_url":null,"source":{"id":"https://openalex.org/S4377196397","display_name":"TigerPrints (Clemson University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I8078737","host_organization_name":"Clemson University","host_organization_lineage":["https://openalex.org/I8078737"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"All Dissertations","raw_type":"text"},{"id":"mag:392363451","doi":null,"is_oa":false,"landing_page_url":"https://tigerprints.clemson.edu/all_dissertations/902/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":235,"referenced_works":["https://openalex.org/W218479827","https://openalex.org/W237976089","https://openalex.org/W266934124","https://openalex.org/W1412300403","https://openalex.org/W1523055845","https://openalex.org/W1536589127","https://openalex.org/W1546403019","https://openalex.org/W1559903407","https://openalex.org/W1559948142","https://openalex.org/W1826739332","https://openalex.org/W1826929253","https://openalex.org/W1853037896","https://openalex.org/W1905710229","https://openalex.org/W1914622032","https://openalex.org/W1948827876","https://openalex.org/W1964024317","https://openalex.org/W1964250029","https://openalex.org/W1965109985","https://openalex.org/W1965751301","https://openalex.org/W1966734218","https://openalex.org/W1968852938","https://openalex.org/W1968985568","https://openalex.org/W1969610395","https://openalex.org/W1970671052","https://openalex.org/W1971393450","https://openalex.org/W1971422523","https://openalex.org/W1971666316","https://openalex.org/W1971757965","https://openalex.org/W1971826881","https://openalex.org/W1971860231","https://openalex.org/W1971925060","https://openalex.org/W1972060131","https://openalex.org/W1974087457","https://openalex.org/W1974694396","https://openalex.org/W1974853989","https://openalex.org/W1976175757","https://openalex.org/W1976603138","https://openalex.org/W1979189704","https://openalex.org/W1979737844","https://openalex.org/W1980423337","https://openalex.org/W1981184057","https://openalex.org/W1981207398","https://openalex.org/W1981390981","https://openalex.org/W1981626955","https://openalex.org/W1982573923","https://openalex.org/W1982699019","https://openalex.org/W1986502110","https://openalex.org/W1987829448","https://openalex.org/W1987851402","https://openalex.org/W1988369809","https://openalex.org/W1989398255","https://openalex.org/W1991918289","https://openalex.org/W1992912400","https://openalex.org/W1994448619","https://openalex.org/W1998936301","https://openalex.org/W1999142965","https://openalex.org/W1999382343","https://openalex.org/W2000061441","https://openalex.org/W2001672152","https://openalex.org/W2001848436","https://openalex.org/W2001948670","https://openalex.org/W2002864777","https://openalex.org/W2004352246","https://openalex.org/W2004974336","https://openalex.org/W2005397161","https://openalex.org/W2005570632","https://openalex.org/W2006097114","https://openalex.org/W2006670683","https://openalex.org/W2006697833","https://openalex.org/W2008498323","https://openalex.org/W2008549617","https://openalex.org/W2008570185","https://openalex.org/W2009401150","https://openalex.org/W2009803502","https://openalex.org/W2010009166","https://openalex.org/W2010028369","https://openalex.org/W2010653732","https://openalex.org/W2011286401","https://openalex.org/W2011611583","https://openalex.org/W2012991711","https://openalex.org/W2013424862","https://openalex.org/W2013560821","https://openalex.org/W2013877811","https://openalex.org/W2014418136","https://openalex.org/W2014611703","https://openalex.org/W2015560109","https://openalex.org/W2016364242","https://openalex.org/W2016379859","https://openalex.org/W2016469284","https://openalex.org/W2017519822","https://openalex.org/W2018967387","https://openalex.org/W2019049058","https://openalex.org/W2019964351","https://openalex.org/W2020105952","https://openalex.org/W2020267609","https://openalex.org/W2020411326","https://openalex.org/W2021229050","https://openalex.org/W2021635663","https://openalex.org/W2022503973","https://openalex.org/W2022778645","https://openalex.org/W2022987546","https://openalex.org/W2023611955","https://openalex.org/W2023669416","https://openalex.org/W2024165279","https://openalex.org/W2024606012","https://openalex.org/W2024997255","https://openalex.org/W2028102269","https://openalex.org/W2029557673","https://openalex.org/W2029929965","https://openalex.org/W2029997569","https://openalex.org/W2030071610","https://openalex.org/W2030529015","https://openalex.org/W2030594278","https://openalex.org/W2031819880","https://openalex.org/W2032041876","https://openalex.org/W2036232758","https://openalex.org/W2037188360","https://openalex.org/W2037342598","https://openalex.org/W2037441342","https://openalex.org/W2038618362","https://openalex.org/W2039847447","https://openalex.org/W2041192165","https://openalex.org/W2043688717","https://openalex.org/W2043710292","https://openalex.org/W2043969520","https://openalex.org/W2044168994","https://openalex.org/W2044531160","https://openalex.org/W2044940018","https://openalex.org/W2048309867","https://openalex.org/W2048555796","https://openalex.org/W2048969281","https://openalex.org/W2050385572","https://openalex.org/W2051146664","https://openalex.org/W2052504315","https://openalex.org/W2053622056","https://openalex.org/W2053785759","https://openalex.org/W2055811595","https://openalex.org/W2056022473","https://openalex.org/W2056594432","https://openalex.org/W2057985642","https://openalex.org/W2060066334","https://openalex.org/W2060150997","https://openalex.org/W2060411004","https://openalex.org/W2062113472","https://openalex.org/W2062815826","https://openalex.org/W2063091963","https://openalex.org/W2065205296","https://openalex.org/W2068954221","https://openalex.org/W2069901183","https://openalex.org/W2070275396","https://openalex.org/W2070279020","https://openalex.org/W2070859489","https://openalex.org/W2071225599","https://openalex.org/W2072088763","https://openalex.org/W2072230362","https://openalex.org/W2072348601","https://openalex.org/W2072860264","https://openalex.org/W2073070652","https://openalex.org/W2074581135","https://openalex.org/W2075604321","https://openalex.org/W2076358165","https://openalex.org/W2077492410","https://openalex.org/W2078415627","https://openalex.org/W2078424158","https://openalex.org/W2078477332","https://openalex.org/W2079341791","https://openalex.org/W2081811802","https://openalex.org/W2081981621","https://openalex.org/W2082657178","https://openalex.org/W2082797093","https://openalex.org/W2084602576","https://openalex.org/W2086795949","https://openalex.org/W2087403807","https://openalex.org/W2087480377","https://openalex.org/W2088134976","https://openalex.org/W2091548691","https://openalex.org/W2091749730","https://openalex.org/W2091770324","https://openalex.org/W2092920884","https://openalex.org/W2092945382","https://openalex.org/W2094061697","https://openalex.org/W2095438561","https://openalex.org/W2096661451","https://openalex.org/W2097493104","https://openalex.org/W2102617803","https://openalex.org/W2103116706","https://openalex.org/W2104478003","https://openalex.org/W2107966909","https://openalex.org/W2108739912","https://openalex.org/W2109119392","https://openalex.org/W2111320164","https://openalex.org/W2112756227","https://openalex.org/W2113174175","https://openalex.org/W2115154144","https://openalex.org/W2116060738","https://openalex.org/W2117751967","https://openalex.org/W2119355515","https://openalex.org/W2119912258","https://openalex.org/W2121868928","https://openalex.org/W2125299541","https://openalex.org/W2128627308","https://openalex.org/W2129133439","https://openalex.org/W2129365218","https://openalex.org/W2136134183","https://openalex.org/W2138218345","https://openalex.org/W2144692401","https://openalex.org/W2144868623","https://openalex.org/W2146531742","https://openalex.org/W2146990413","https://openalex.org/W2148032599","https://openalex.org/W2150148407","https://openalex.org/W2157079028","https://openalex.org/W2158240118","https://openalex.org/W2158944838","https://openalex.org/W2161229173","https://openalex.org/W2163627907","https://openalex.org/W2164298199","https://openalex.org/W2164824970","https://openalex.org/W2165132471","https://openalex.org/W2166949767","https://openalex.org/W2168065883","https://openalex.org/W2170836456","https://openalex.org/W2171613935","https://openalex.org/W2184578490","https://openalex.org/W2193804668","https://openalex.org/W2261537439","https://openalex.org/W2318515345","https://openalex.org/W2324810756","https://openalex.org/W2331165043","https://openalex.org/W2377191039","https://openalex.org/W2384697622","https://openalex.org/W2527389183","https://openalex.org/W3095742653","https://openalex.org/W3134747502","https://openalex.org/W4232135728"],"related_works":["https://openalex.org/W3164704124","https://openalex.org/W7004925065","https://openalex.org/W2605329766","https://openalex.org/W2055811595","https://openalex.org/W2316752349","https://openalex.org/W2102468842","https://openalex.org/W2599068253","https://openalex.org/W2737963065","https://openalex.org/W2788221519","https://openalex.org/W2594712754"],"abstract_inverted_index":{"Phenolic":[0],"compounds,":[1],"including":[2,314],"anthocyanins":[3,79,192,302,337],"in":[4,21,107,211,303,334,342],"muscadines":[5,237],"have":[6],"attracted":[7],"much":[8],"attention":[9],"due":[10],"to":[11,83,112,187,288],"their":[12,97,113],"diverse":[13],"biological":[14],"activities.":[15,70],"With":[16],"bioassays":[17],"of":[18,23,60,91,121,199,208,236,297],"antioxidant":[19,52,69,98,114],"activities":[20,99,120,178,242],"terms":[22],"total":[24,28,32,36],"phenolic":[25,105,141,298],"content":[26,30,34,38],"(TPC),":[27],"flavonoid":[29],"(TFC)":[31],"anthocyanin":[33],"(TAC),":[35],"procyanidin":[37],"(TPA),":[39],"oxygen":[40],"radical":[41,46],"absorbance":[42],"capacity":[43,59],"(ORAC),":[44],"ABTS":[45],"scavenging":[47],"Activity":[48],"(ABTS),":[49],"ferric":[50],"reducing":[51],"power":[53],"(FRAP),":[54],"and":[55,80,94,118,131,142,145,156,182,193,221,233,254,263,301,327,345],"oil":[56],"peroxidation":[57],"inhibitory":[58],"all":[61],"muscadine":[62,65,108,123,171,200,248,304,344],"samples,":[63],"the":[64,78,122,140,146,159,163,170,175,180,188,205,231,239,261,294,319,331,339],"grapes":[66],"showed":[67,168],"strong":[68,176,240],"The":[71,165,196,226],"liquid-liquid":[72],"organic":[73],"solvent":[74],"extraction":[75],"successfully":[76,271],"separated":[77],"other":[81,194,213,245],"phenolics":[82,333],"different":[84],"fractions.":[85,246],"Strong":[86],"linear":[87],"relationship":[88],"between":[89],"responses":[90],"TPC,":[92],"TAC":[93],"TPA":[95],"versus":[96],"was":[100,202],"assessed,":[101],"which":[102,282],"suggested":[103,322],"that":[104,139,169,173,323],"compounds":[106],"extracts":[109,124,144,172,201],"contributed":[110],"significantly":[111],"potential.":[115],"Inhibitory":[116],"mode":[117,161],"anti-diabetic":[119],"on":[125,179],"three":[126],"enzymes,":[127],"i.e.":[128],"alpha-glucosidase,":[129],"alpha-amylase":[130],"pancreatic":[132],"lipase,":[133],"were":[134,330,338],"investigated.":[135],"This":[136,268],"study":[137,269],"demonstrated":[138],"anthocyanin-rich":[143],"selected":[147],"representative":[148],"phytochemicals":[149],"(i.e.,":[150],"catechin,":[151],"quencertin,":[152],"ellagic":[153,328],"acid,":[154,325],"cyanidin":[155],"cyanidin-3,5-diglucoside)":[157],"obeyed":[158],"competitive":[160],"against":[162,260],"enzymes.":[164],"results":[166,227],"also":[167,270],"possessed":[174],"anti-diabetes":[177],"alpha-glucosidase":[181],"lipase":[183],"might":[184],"be":[185],"ascribed":[186],"major":[189],"contributions":[190],"from":[191,318],"phenolics.":[195],"anti-cancer":[197],"activity":[198],"confirmed":[203],"by":[204,309],"dose-dependent":[206],"inhibition":[207],"cell":[209,215,266],"proliferation":[210],"two":[212],"cancer":[214,218,223,265],"lines,":[216],"colon":[217,262],"cells":[219,224],"HT29":[220],"breast":[222,264],"MCF-7.":[225],"indicated":[228],"that,":[229],"generally,":[230],"phenolics-rich":[232],"anthocyanins-rich":[234],"fractions":[235],"exhibit":[238],"anti-proliferative":[241],"rather":[243],"than":[244],"Therefore,":[247],"fruits,":[249],"as":[250,252],"well":[251],"seed":[253],"skin":[255,346],"portions":[256],"had":[257],"health-promoting":[258],"properties":[259],"growth.":[267],"established":[272],"a":[273,284],"high-performance":[274],"liquid-chromatography":[275],"Evaporative":[276],"light":[277],"scattering":[278],"detector":[279,286],"(HPLC-ELSD)":[280],"method,":[281],"is":[283],"universal":[285],"able":[287],"detect":[289],"almost":[290],"any":[291],"compound,":[292],"for":[293],"simultaneous":[295],"determination":[296],"acids,":[299],"flavonoids":[300],"grape.":[305],"Further":[306],"chromatographic":[307],"analysis":[308],"HPLC-UV-MS":[310],"identified":[311],"24":[312],"phenolics,":[313],"5":[315],"anthocyanins.":[316],"Results":[317],"HPLC-MS":[320],"quantification":[321],"gallic":[324],"proanthocyanidins,":[326],"acid":[329],"main":[332,340],"muscadines,":[335],"while":[336],"ones":[341],"Noble":[343],"portion.":[347]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
