{"id":"https://openalex.org/W39105223","doi":"https://doi.org/10.1007/s00103-006-0007-7","title":"Glykotoxine und Zellaktivierung","display_name":"Glykotoxine und Zellaktivierung","publication_year":2006,"publication_date":"2006-08-01","ids":{"openalex":"https://openalex.org/W39105223","doi":"https://doi.org/10.1007/s00103-006-0007-7","mag":"39105223","pmid":"https://pubmed.ncbi.nlm.nih.gov/16897151"},"language":"de","primary_location":{"id":"doi:10.1007/s00103-006-0007-7","doi":"https://doi.org/10.1007/s00103-006-0007-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00103-006-0007-7","pdf_url":null,"source":{"id":"https://openalex.org/S62458012","display_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","issn_l":"0007-5914","issn":["0007-5914","1436-9990","1437-1588"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020497141","display_name":"Andreas Michalsen","orcid":"https://orcid.org/0000-0002-9145-7246","observed_orcids":["https://orcid.org/0000-0002-9145-7246"]},"institutions":[{"id":"https://openalex.org/I4210146447","display_name":"Kliniken Essen-Mitte","ror":"https://ror.org/03v958f45","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210146447"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"A. Michalsen","raw_affiliation_strings":["Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen, BRD. andreas.michalsen@uni-essen.de","Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Essen, BRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen, BRD. andreas.michalsen@uni-essen.de","institution_ids":["https://openalex.org/I4210146447"]},{"raw_affiliation_string":"Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Essen, BRD","institution_ids":["https://openalex.org/I4210146447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065997689","display_name":"Angelika Bierhaus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Bierhaus","raw_affiliation_strings":["Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD","institution_ids":["https://openalex.org/I2802164966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067599146","display_name":"Peter P. Nawroth","orcid":"https://orcid.org/0000-0002-6134-7804","observed_orcids":["https://orcid.org/0000-0002-6134-7804"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. P. Nawroth","raw_affiliation_strings":["Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD","institution_ids":["https://openalex.org/I2802164966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111717790","display_name":"G. J. Dobos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. J. Dobos","raw_affiliation_strings":["Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e4tsklinik Heidelberg, Heidelberg, BRD","institution_ids":["https://openalex.org/I2802164966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020497141"],"corresponding_institution_ids":["https://openalex.org/I4210146447"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":null,"fwci":0.3854,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.5538695,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"49","issue":"8","first_page":"773","last_page":"779"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11745","display_name":"Potato Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-glycation-end-products","display_name":"advanced glycation end products","score":0.9890000224113464},{"id":"https://openalex.org/keywords/rage-receptor","display_name":"RAGE receptor","score":0.6650000214576721},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4440000057220459},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9909999966621399},{"id":"https://openalex.org/keywords/psychosocial-stress","display_name":"psychosocial stress","score":0.7760000228881836},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mediterranean-diet","display_name":"Mediterranean diet","score":0.8169999718666077},{"id":"https://openalex.org/keywords/vegetarian-diet","display_name":"vegetarian diet","score":0.8489999771118164},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.9929999709129333},{"id":"https://openalex.org/keywords/intermittent-fasting","display_name":"intermittent fasting","score":0.9890000224113464},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.6859999895095825},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9700000286102295},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.9599999785423279}],"concepts":[{"id":"https://openalex.org/C147990577","wikidata":"https://www.wikidata.org/wiki/Q25790","display_name":"Glycation","level":3,"score":0.827454686164856},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7188677191734314},{"id":"https://openalex.org/C2778857457","wikidata":"https://www.wikidata.org/wiki/Q153641","display_name":"Rage (emotion)","level":2,"score":0.7091224193572998},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6724875569343567},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5811289548873901},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5448740124702454},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5408511757850647},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5077260732650757},{"id":"https://openalex.org/C2778962194","wikidata":"https://www.wikidata.org/wiki/Q47564","display_name":"Mediterranean diet","level":2,"score":0.4516505300998688},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3771066665649414},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.34970754384994507},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25736093521118164},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000067759","descriptor_name":"Receptor for Advanced Glycation End Products","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002468","descriptor_name":"Cell Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009747","descriptor_name":"Nutritional Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011322","descriptor_name":"Primary Prevention","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D040242","descriptor_name":"Risk Reduction Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00103-006-0007-7","doi":"https://doi.org/10.1007/s00103-006-0007-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00103-006-0007-7","pdf_url":null,"source":{"id":"https://openalex.org/S62458012","display_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","issn_l":"0007-5914","issn":["0007-5914","1436-9990","1437-1588"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","raw_type":"journal-article"},{"id":"pmid:16897151","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16897151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","raw_type":"Journal Article"},{"id":"mag:2978832731","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16897151/","pdf_url":null,"source":{"id":"https://openalex.org/S62458012","display_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","issn_l":"0007-5914","issn":["0007-5914","1436-9990","1437-1588"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","raw_type":null},{"id":"mag:3183306614","doi":null,"is_oa":false,"landing_page_url":"https://link.springer.com/content/pdf/10.1007/s00103-006-0007-7.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S62458012","display_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","issn_l":"0007-5914","issn":["0007-5914","1436-9990","1437-1588"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W84557252","https://openalex.org/W1672581883","https://openalex.org/W1862536371","https://openalex.org/W1915022071","https://openalex.org/W1965591294","https://openalex.org/W1971209988","https://openalex.org/W1986059252","https://openalex.org/W1995801352","https://openalex.org/W1996685677","https://openalex.org/W1999338471","https://openalex.org/W2013730613","https://openalex.org/W2018658316","https://openalex.org/W2021001924","https://openalex.org/W2056508024","https://openalex.org/W2057961754","https://openalex.org/W2058699849","https://openalex.org/W2062273929","https://openalex.org/W2062389480","https://openalex.org/W2064532629","https://openalex.org/W2066963386","https://openalex.org/W2067366553","https://openalex.org/W2068139734","https://openalex.org/W2071675524","https://openalex.org/W2072265321","https://openalex.org/W2076163944","https://openalex.org/W2084536221","https://openalex.org/W2094981066","https://openalex.org/W2096255617","https://openalex.org/W2106867120","https://openalex.org/W2108355568","https://openalex.org/W2109334664","https://openalex.org/W2110150101","https://openalex.org/W2113991276","https://openalex.org/W2122091192","https://openalex.org/W2130633974","https://openalex.org/W2130892097","https://openalex.org/W2144575916","https://openalex.org/W2150249152","https://openalex.org/W2150844478","https://openalex.org/W2151454086","https://openalex.org/W2155141923","https://openalex.org/W2164424425","https://openalex.org/W2166950021","https://openalex.org/W2274476794","https://openalex.org/W2320280184","https://openalex.org/W2396817849","https://openalex.org/W2916990049","https://openalex.org/W4285719527","https://openalex.org/W4389384585"],"related_works":["https://openalex.org/W1965011485","https://openalex.org/W4399915526","https://openalex.org/W2077881807","https://openalex.org/W2192953218","https://openalex.org/W1909944278","https://openalex.org/W7145824483","https://openalex.org/W2585705777","https://openalex.org/W3195073364","https://openalex.org/W1999723121","https://openalex.org/W2002616153"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}