{"id":"https://openalex.org/W3895122","doi":null,"title":"Heterophile antibodies in pathologic human sera resembling antibodies stimulated by foreign species sera.","display_name":"Heterophile antibodies in pathologic human sera resembling antibodies stimulated by foreign species sera.","publication_year":1976,"publication_date":"1976-07-01","ids":{"openalex":"https://openalex.org/W3895122","mag":"3895122","pmid":"https://pubmed.ncbi.nlm.nih.gov/825336","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1541393"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1541393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1541393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1541393","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109293478","display_name":"Reiji Kasukawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Kasukawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073997692","display_name":"Kyoichi Kano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Kano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065120484","display_name":"MARVIN L. BLOOM","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M L Bloom","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5036426575","display_name":"Felix Milgrom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Milgrom","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2471,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.74831914,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"25","issue":"1","first_page":"122","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.7681000232696533,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.7681000232696533,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.10890000313520432,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.07329999655485153,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heterophile-antibodies","display_name":"heterophile antibodies","score":0.984000027179718},{"id":"https://openalex.org/keywords/bovine-erythrocytes","display_name":"bovine erythrocytes","score":0.8970000147819519},{"id":"https://openalex.org/keywords/guinea-pig-kidney","display_name":"guinea pig kidney","score":0.6010000109672546},{"id":"https://openalex.org/keywords/antibody-antigen-interaction","display_name":"antigen-antibody reaction","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2777774473","wikidata":"https://www.wikidata.org/wiki/Q5747444","display_name":"Heterophile","level":3,"score":0.882453441619873},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.8477082252502441},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6934630274772644},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4910616874694824},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4094986617565155},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.34645578265190125},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34257885813713074}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000910","descriptor_name":"Antibodies, Heterophile","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005779","descriptor_name":"Immunodiffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006460","descriptor_name":"Hemolysin Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:1541393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1541393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmid:825336","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/825336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"},{"id":"mag:3895122","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/825336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1541393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1541393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W181494312","https://openalex.org/W1487202078","https://openalex.org/W1544849449","https://openalex.org/W1893548152","https://openalex.org/W1972464253","https://openalex.org/W1975068581","https://openalex.org/W1981711406","https://openalex.org/W2009548989","https://openalex.org/W2018377262","https://openalex.org/W2155661060","https://openalex.org/W2165229582","https://openalex.org/W2409856526","https://openalex.org/W4313375078"],"related_works":["https://openalex.org/W92183741","https://openalex.org/W2311298877","https://openalex.org/W66782984","https://openalex.org/W1580439463","https://openalex.org/W2394846895","https://openalex.org/W1565201657","https://openalex.org/W2031920600","https://openalex.org/W1990205735","https://openalex.org/W2428284877","https://openalex.org/W1539460764"],"abstract_inverted_index":{"Studies":[0],"were":[1,153,177],"performed":[2],"on":[3],"heterphile":[4],"antibodies":[5,23,38,47,58,152,176,181],"originally":[6],"described":[7],"by":[8,39,48,183],"Hanganutziu":[9],"and":[10,12,44,88,94,101,105],"Deicher":[11],"referred":[13],"to":[14],"as":[15,25],"H-D":[16,57,136,143,151,180],"antibodies.":[17],"It":[18],"was":[19,54],"confirmed":[20],"that":[21,56,164],"these":[22],"appear":[24],"a":[26],"result":[27],"of":[28,30,70,77,81,90,99,103,116,171,185],"injections":[29,170,184],"foreign":[31,172,186],"species":[32,173],"sera.":[33,150,174,187],"They":[34],"differ":[35],"from":[36,45,179],"Forssman":[37],"combining":[40],"with":[41,50,121,142,148],"bovine":[42,71,86],"erythrocytes":[43,139],"Paul-Bunnell":[46,82],"reacting":[49],"guinea-pig":[51],"kidney.":[52],"it":[53],"demonstrated":[55],"react":[59],"in":[60,156],"double":[61],"diffusion":[62],"gel":[63],"precipitation":[64,131],"tests":[65],"with:":[66],"(1)":[67],"crude":[68],"extract":[69,79],"erythrocyte":[72],"stromata;":[73],"(2)":[74],"purified":[75],"fraction":[76],"this":[78],"devoid":[80],"antigen;":[83],"(3)":[84],"whole":[85],"serum":[87,100],"sera":[89,160],"several":[91,106,125],"other":[92,107],"species;":[93],"(4)":[95],"thermostable":[96],"ethanol-insoluble":[97],"freactions":[98],"organs":[102],"oxen":[104],"species.":[108],"These":[109],"various":[110],"antigenic":[111],"preparations":[112],"gave":[113],"usually":[114],"reactions":[115],"complete":[117],"or":[118,128],"partial":[119],"identity":[120],"each":[122],"other.":[123],"In":[124],"instances,":[126],"two":[127],"even":[129],"three":[130],"lines":[132],"could":[133],"be":[134],"detected.":[135],"negative":[137],"human":[138,159],"became":[140],"coated":[141],"antigen":[144],"upon":[145],"simple":[146],"incubation":[147],"H-D-positive":[149],"also":[154],"detected":[155],"some":[157],"pathological":[158],"without":[161],"any":[162],"indication":[163],"the":[165],"patients":[166],"had":[167],"ever":[168],"received":[169],"Such":[175],"undistinguishable":[178],"engendered":[182]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}