{"id":"https://openalex.org/W3893579","doi":null,"title":"Nutritional and toxicological effects of short-term ingestion of aluminum by the rat.","display_name":"Nutritional and toxicological effects of short-term ingestion of aluminum by the rat.","publication_year":1987,"publication_date":"1987-06-01","ids":{"openalex":"https://openalex.org/W3893579","mag":"3893579","pmid":"https://pubmed.ncbi.nlm.nih.gov/3628968"},"language":"en","primary_location":{"id":"pmid:3628968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3628968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research communications in chemical pathology and pharmacology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034574596","display_name":"Jos\u00e9 L. Domingo","orcid":"https://orcid.org/0000-0001-6647-9470","observed_orcids":["https://orcid.org/0000-0001-6647-9470"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J L Domingo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113679893","display_name":"J.M. Llobet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J M Llobet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064260772","display_name":"Mercedes G\u00f3mez","orcid":"https://orcid.org/0000-0003-1892-5557","observed_orcids":["https://orcid.org/0000-0003-1892-5557"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M G\u00f3mez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017199049","display_name":"Josep Maria Tom\u00e0s","orcid":"https://orcid.org/0000-0002-0406-0006","observed_orcids":["https://orcid.org/0000-0002-0406-0006"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J M Tom\u00e1s","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113756178","display_name":"J. Corbella","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Corbella","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0692,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.74332895,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"56","issue":"3","first_page":"409","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aluminum-toxicity","display_name":"aluminum toxicity","score":0.878000020980835},{"id":"https://openalex.org/keywords/aluminum-nitrate","display_name":"aluminum nitrate","score":0.9449999928474426},{"id":"https://openalex.org/keywords/oral-ingestion","display_name":"oral ingestion","score":0.7850000262260437},{"id":"https://openalex.org/keywords/growth-retardation","display_name":"growth retardation","score":0.6940000057220459},{"id":"https://openalex.org/keywords/nutrient-effects","display_name":"nutrient effects","score":0.6159999966621399},{"id":"https://openalex.org/keywords/hematology","display_name":"hematology","score":0.5640000104904175},{"id":"https://openalex.org/keywords/plasma-chemistry","display_name":"plasma chemistry","score":0.9710000157356262},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.9129999876022339},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.904794454574585},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.5022685527801514},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.49323171377182007},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4658530354499817},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.4614715576171875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45616963505744934},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4163650870323181},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.41551274061203003},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.4079620838165283},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4058338701725006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3550962805747986},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2738291919231415}],"mesh":[{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004231","descriptor_name":"Diuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3628968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3628968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research communications in chemical pathology and pharmacology","raw_type":"Journal Article"},{"id":"mag:3893579","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3628968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2419172722","https://openalex.org/W1989313786","https://openalex.org/W2183187540","https://openalex.org/W2468855865","https://openalex.org/W1958980517","https://openalex.org/W2079298579","https://openalex.org/W2109823668","https://openalex.org/W2137984040","https://openalex.org/W2074376304","https://openalex.org/W2046382766"],"abstract_inverted_index":{"Aluminum":[0,71],"nitrate":[1,49],"was":[2],"given":[3],"orally":[4],"to":[5],"four":[6],"groups":[7],"of":[8,15,20,47,95],"female":[9],"Sprague-Dawley":[10],"rats":[11],"over":[12],"a":[13,54],"period":[14],"one-hundred":[16],"days":[17],"at":[18],"doses":[19],"0,":[21],"360,":[22],"720":[23],"and":[24,38,79],"3600":[25],"mg/kg/day.":[26],"Rats":[27],"were":[28,63],"monitored":[29],"for":[30,67],"weight":[31,86],"gain,":[32],"food":[33],"intake,":[34],"drinking":[35],"water,":[36],"hematology":[37],"plasma":[39],"chemistry.":[40],"The":[41,60,93],"results":[42],"show":[43,90],"that":[44],"the":[45,51,68,77,100],"ingestion":[46],"aluminum":[48,97],"by":[50],"rat":[52],"caused":[53],"significant":[55,91],"decrease":[56],"in":[57,76,99],"its":[58],"growth.":[59],"nutritional":[61],"parameters":[62],"always":[64],"significantly":[65],"lower":[66],"treated":[69],"animals.":[70],"did":[72,88],"not":[73,89],"accumulate":[74],"dose-dependently":[75],"organs":[78],"tissues":[80],"analysed.":[81],"Histopathological":[82],"studies,":[83],"including":[84],"organ":[85],"determinations,":[87],"changes.":[92],"possibility":[94],"oral":[96],"intoxication":[98],"human":[101],"would":[102],"be":[103],"very":[104],"low.":[105]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}