{"id":"https://openalex.org/W38359003","doi":"https://doi.org/10.1007/978-1-4613-1599-5_4","title":"The ras family of oncogenes","display_name":"The ras family of oncogenes","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W38359003","doi":"https://doi.org/10.1007/978-1-4613-1599-5_4","mag":"38359003","pmid":"https://pubmed.ncbi.nlm.nih.gov/2577006"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4613-1599-5_4","doi":"https://doi.org/10.1007/978-1-4613-1599-5_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-1599-5_4","pdf_url":null,"source":{"id":"https://openalex.org/S2755761368","display_name":"Cancer treatment and research","issn_l":"0927-3042","issn":["0927-3042","2509-8497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Treatment and Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4254355184","display_name":"Oncogenes"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064063895","display_name":"Channing J. Der","orcid":"https://orcid.org/0000-0002-7751-2747","observed_orcids":["https://orcid.org/0000-0002-7751-2747"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Channing J. Der","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064063895"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0385,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.86080802,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"47","issue":null,"first_page":"73","last_page":"119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ras-genes","display_name":"ras gene","score":0.7250000238418579},{"id":"https://openalex.org/keywords/oncogenes","display_name":"oncogenes","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cellular-oncogenes","display_name":"cellular oncogenes","score":0.7639999985694885},{"id":"https://openalex.org/keywords/human-carcinogenesis","display_name":"human carcinogenesis","score":0.7390000224113464},{"id":"https://openalex.org/keywords/v-h-ras","display_name":"v-H-ras","score":0.7160000205039978},{"id":"https://openalex.org/keywords/rna-tumor-viruses","display_name":"RNA tumor viruses","score":0.8100000023841858},{"id":"https://openalex.org/keywords/molecular-mechanisms-of-cancer","display_name":"molecular mechanisms of cancer","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.8580406904220581},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7401798963546753},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7153798937797546},{"id":"https://openalex.org/C2911062167","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Proto-Oncogenes","level":5,"score":0.4850844442844391},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.45561110973358154},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.42966142296791077},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3612663745880127},{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.21198007464408875},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.15363842248916626}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011905","descriptor_name":"Genes, ras","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016283","descriptor_name":"Proto-Oncogene Proteins p21(ras)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4613-1599-5_4","doi":"https://doi.org/10.1007/978-1-4613-1599-5_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-1599-5_4","pdf_url":null,"source":{"id":"https://openalex.org/S2755761368","display_name":"Cancer treatment and research","issn_l":"0927-3042","issn":["0927-3042","2509-8497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Treatment and Research","raw_type":"book-chapter"},{"id":"pmid:2577006","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2577006","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer treatment and research","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1992624342","display_name":null,"funder_award_id":"CA42978","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":279,"referenced_works":["https://openalex.org/W35071699","https://openalex.org/W44861040","https://openalex.org/W95173797","https://openalex.org/W196481606","https://openalex.org/W196495617","https://openalex.org/W228407023","https://openalex.org/W962563956","https://openalex.org/W1480125182","https://openalex.org/W1490645937","https://openalex.org/W1500314244","https://openalex.org/W1508018835","https://openalex.org/W1511561312","https://openalex.org/W1513108917","https://openalex.org/W1532943864","https://openalex.org/W1533781057","https://openalex.org/W1552158310","https://openalex.org/W1556438409","https://openalex.org/W1558802435","https://openalex.org/W1583035638","https://openalex.org/W1600627109","https://openalex.org/W1605851497","https://openalex.org/W1632248130","https://openalex.org/W1663526709","https://openalex.org/W1666400257","https://openalex.org/W1676701054","https://openalex.org/W1752162927","https://openalex.org/W1755131724","https://openalex.org/W1756625003","https://openalex.org/W1783564364","https://openalex.org/W1794163232","https://openalex.org/W1806128296","https://openalex.org/W1819297632","https://openalex.org/W1829921871","https://openalex.org/W1833267103","https://openalex.org/W1835109348","https://openalex.org/W1838818735","https://openalex.org/W1842672419","https://openalex.org/W1858393860","https://openalex.org/W1861041353","https://openalex.org/W1868145563","https://openalex.org/W1869481189","https://openalex.org/W1878138973","https://openalex.org/W1887642177","https://openalex.org/W1892956974","https://openalex.org/W1906271222","https://openalex.org/W1908005614","https://openalex.org/W1918461347","https://openalex.org/W1947022122","https://openalex.org/W1964201498","https://openalex.org/W1964839077","https://openalex.org/W1965058394","https://openalex.org/W1967452306","https://openalex.org/W1967905567","https://openalex.org/W1969006090","https://openalex.org/W1969560454","https://openalex.org/W1969814518","https://openalex.org/W1970218184","https://openalex.org/W1970587959","https://openalex.org/W1971972605","https://openalex.org/W1972013545","https://openalex.org/W1973568385","https://openalex.org/W1973677994","https://openalex.org/W1973800266","https://openalex.org/W1977670183","https://openalex.org/W1977876290","https://openalex.org/W1978274173","https://openalex.org/W1979447769","https://openalex.org/W1979527189","https://openalex.org/W1979646488","https://openalex.org/W1980234539","https://openalex.org/W1982259691","https://openalex.org/W1984240546","https://openalex.org/W1984789478","https://openalex.org/W1985417906","https://openalex.org/W1986383101","https://openalex.org/W1986398796","https://openalex.org/W1986409528","https://openalex.org/W1987325795","https://openalex.org/W1987482586","https://openalex.org/W1988181486","https://openalex.org/W1988797187","https://openalex.org/W1988970153","https://openalex.org/W1989009382","https://openalex.org/W1990513983","https://openalex.org/W1992409084","https://openalex.org/W1993378834","https://openalex.org/W1994331967","https://openalex.org/W1994775044","https://openalex.org/W1995095999","https://openalex.org/W1995561930","https://openalex.org/W1995723368","https://openalex.org/W1996224662","https://openalex.org/W1996729627","https://openalex.org/W1996830465","https://openalex.org/W1996942263","https://openalex.org/W1997385847","https://openalex.org/W1997940906","https://openalex.org/W1998023125","https://openalex.org/W1998132110","https://openalex.org/W1998250646","https://openalex.org/W1999175930","https://openalex.org/W1999275756","https://openalex.org/W1999838666","https://openalex.org/W2001923549","https://openalex.org/W2002680426","https://openalex.org/W2003197672","https://openalex.org/W2003267467","https://openalex.org/W2003914909","https://openalex.org/W2004512194","https://openalex.org/W2005090417","https://openalex.org/W2005513340","https://openalex.org/W2007648159","https://openalex.org/W2007675615","https://openalex.org/W2008095094","https://openalex.org/W2008296946","https://openalex.org/W2011857798","https://openalex.org/W2012156489","https://openalex.org/W2012657439","https://openalex.org/W2012806962","https://openalex.org/W2013026243","https://openalex.org/W2013646631","https://openalex.org/W2013782668","https://openalex.org/W2013973825","https://openalex.org/W2014656185","https://openalex.org/W2014798701","https://openalex.org/W2015391676","https://openalex.org/W2015936619","https://openalex.org/W2016620103","https://openalex.org/W2018228515","https://openalex.org/W2020358132","https://openalex.org/W2021181413","https://openalex.org/W2022213176","https://openalex.org/W2022870173","https://openalex.org/W2023023900","https://openalex.org/W2023335056","https://openalex.org/W2024006334","https://openalex.org/W2024084862","https://openalex.org/W2026070941","https://openalex.org/W2026461778","https://openalex.org/W2027104051","https://openalex.org/W2027163118","https://openalex.org/W2028383523","https://openalex.org/W2028519621","https://openalex.org/W2030981141","https://openalex.org/W2031332665","https://openalex.org/W2032923234","https://openalex.org/W2034741274","https://openalex.org/W2035009681","https://openalex.org/W2035049668","https://openalex.org/W2035208645","https://openalex.org/W2035363409","https://openalex.org/W2035869432","https://openalex.org/W2036744157","https://openalex.org/W2039742554","https://openalex.org/W2040976289","https://openalex.org/W2042371773","https://openalex.org/W2043592489","https://openalex.org/W2045067239","https://openalex.org/W2045322395","https://openalex.org/W2045652806","https://openalex.org/W2045878775","https://openalex.org/W2046955948","https://openalex.org/W2046961979","https://openalex.org/W2047101291","https://openalex.org/W2048784760","https://openalex.org/W2049463632","https://openalex.org/W2049596148","https://openalex.org/W2050041621","https://openalex.org/W2052830851","https://openalex.org/W2053098386","https://openalex.org/W2053501297","https://openalex.org/W2053813431","https://openalex.org/W2054017818","https://openalex.org/W2054904912","https://openalex.org/W2056454654","https://openalex.org/W2056519542","https://openalex.org/W2056786827","https://openalex.org/W2057159445","https://openalex.org/W2057163724","https://openalex.org/W2057385958","https://openalex.org/W2058333572","https://openalex.org/W2058491704","https://openalex.org/W2058511768","https://openalex.org/W2058649415","https://openalex.org/W2058980559","https://openalex.org/W2059548932","https://openalex.org/W2059760774","https://openalex.org/W2060032114","https://openalex.org/W2060242664","https://openalex.org/W2061129160","https://openalex.org/W2061628918","https://openalex.org/W2061950562","https://openalex.org/W2062039330","https://openalex.org/W2063228215","https://openalex.org/W2063361805","https://openalex.org/W2063837791","https://openalex.org/W2064075925","https://openalex.org/W2064916160","https://openalex.org/W2065011248","https://openalex.org/W2065951262","https://openalex.org/W2067900929","https://openalex.org/W2068877244","https://openalex.org/W2070776635","https://openalex.org/W2071697240","https://openalex.org/W2073683003","https://openalex.org/W2074951828","https://openalex.org/W2075612889","https://openalex.org/W2077102469","https://openalex.org/W2077788859","https://openalex.org/W2078425071","https://openalex.org/W2078792023","https://openalex.org/W2079730923","https://openalex.org/W2080875376","https://openalex.org/W2080910520","https://openalex.org/W2081335151","https://openalex.org/W2082777785","https://openalex.org/W2083690533","https://openalex.org/W2084832908","https://openalex.org/W2087134510","https://openalex.org/W2087411905","https://openalex.org/W2087437369","https://openalex.org/W2087884848","https://openalex.org/W2088130891","https://openalex.org/W2088252707","https://openalex.org/W2088989337","https://openalex.org/W2089396478","https://openalex.org/W2089741493","https://openalex.org/W2091432500","https://openalex.org/W2091936831","https://openalex.org/W2091942447","https://openalex.org/W2092061547","https://openalex.org/W2092727362","https://openalex.org/W2093660936","https://openalex.org/W2093775509","https://openalex.org/W2094816576","https://openalex.org/W2097429159","https://openalex.org/W2097694896","https://openalex.org/W2100256775","https://openalex.org/W2108462977","https://openalex.org/W2113210366","https://openalex.org/W2117079180","https://openalex.org/W2119863891","https://openalex.org/W2120256795","https://openalex.org/W2120829092","https://openalex.org/W2122184612","https://openalex.org/W2126901946","https://openalex.org/W2136757745","https://openalex.org/W2139996811","https://openalex.org/W2143907613","https://openalex.org/W2146529796","https://openalex.org/W2149077527","https://openalex.org/W2150224257","https://openalex.org/W2156872475","https://openalex.org/W2158608327","https://openalex.org/W2160809286","https://openalex.org/W2163141239","https://openalex.org/W2164034599","https://openalex.org/W2165446716","https://openalex.org/W2165540701","https://openalex.org/W2165867884","https://openalex.org/W2167105480","https://openalex.org/W2167875305","https://openalex.org/W2168324949","https://openalex.org/W2180245338","https://openalex.org/W2180795626","https://openalex.org/W2181274840","https://openalex.org/W2259360768","https://openalex.org/W2261371674","https://openalex.org/W2264315731","https://openalex.org/W2308783294","https://openalex.org/W2321031632","https://openalex.org/W2397292236","https://openalex.org/W2410128087","https://openalex.org/W2413517520","https://openalex.org/W2418357216","https://openalex.org/W2419034964","https://openalex.org/W4232777855","https://openalex.org/W4285719527","https://openalex.org/W4300875943"],"related_works":["https://openalex.org/W26132462","https://openalex.org/W2341228894","https://openalex.org/W2026892501","https://openalex.org/W2027615413","https://openalex.org/W2101494379","https://openalex.org/W2013646631","https://openalex.org/W227516826","https://openalex.org/W2226579370","https://openalex.org/W7098621596","https://openalex.org/W1995561930"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
