{"id":"https://openalex.org/W38184667","doi":null,"title":"Wnt\u548c\u6838\u56e0\u5b50-\u03baB\u4fe1\u53f7\u901a\u8def\u5728\u80bf\u7624\u53d1\u751f\u4e2d\u7684\u201c\u5bf9\u8bdd\u201d","display_name":"Wnt\u548c\u6838\u56e0\u5b50-\u03baB\u4fe1\u53f7\u901a\u8def\u5728\u80bf\u7624\u53d1\u751f\u4e2d\u7684\u201c\u5bf9\u8bdd\u201d","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W38184667","mag":"38184667"},"language":"zh-cn","primary_location":{"id":"mag:38184667","doi":null,"is_oa":false,"landing_page_url":"http://www.cqvip.com/qk/95342X/200511/20571877.html","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011027487","display_name":"\u9648\u5eb7\u6770","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u9648\u5eb7\u6770","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5086117603","display_name":"\u9ec4\u5efa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u9ec4\u5efa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00263185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"11","first_page":"817","last_page":"819"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.8817999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.11249999701976776,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12620","display_name":"Signaling Pathways in Disease","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.9940000176429749},{"id":"https://openalex.org/keywords/signaling-crosstalk","display_name":"signaling crosstalk","score":0.7549999952316284},{"id":"https://openalex.org/keywords/tumor-initiation","display_name":"tumor initiation","score":0.6729999780654907},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.5640000104904175},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/downstream-target-genes","display_name":"downstream target genes","score":0.9240000247955322}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.433808833360672}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:38184667","doi":null,"is_oa":false,"landing_page_url":"http://www.cqvip.com/qk/95342X/200511/20571877.html","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2578248066","display_name":null,"funder_award_id":"2146567","funder_id":"https://openalex.org/F4320332172","funder_display_name":"Directorate for Mathematical and Physical Sciences"},{"id":"https://openalex.org/G2751812902","display_name":null,"funder_award_id":"20230014DR","funder_id":"https://openalex.org/F4320337547","funder_display_name":"Laboratory Directed Research and Development"},{"id":"https://openalex.org/G9306211","display_name":null,"funder_award_id":"2011967","funder_id":"https://openalex.org/F4320332172","funder_display_name":"Directorate for Mathematical and Physical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332172","display_name":"Directorate for Mathematical and Physical Sciences","ror":"https://ror.org/029b7h395"},{"id":"https://openalex.org/F4320337547","display_name":"Laboratory Directed Research and Development","ror":"https://ror.org/01e41cf67"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1549226898","https://openalex.org/W1970188810","https://openalex.org/W2027600417","https://openalex.org/W2043175787","https://openalex.org/W2067291168","https://openalex.org/W2132283351","https://openalex.org/W2200974461","https://openalex.org/W2269231467","https://openalex.org/W2300218866","https://openalex.org/W2519005322","https://openalex.org/W2595688496","https://openalex.org/W2620817137","https://openalex.org/W2876380218","https://openalex.org/W2888997748","https://openalex.org/W2905760783","https://openalex.org/W2968302714","https://openalex.org/W3086360679","https://openalex.org/W3092822629","https://openalex.org/W3104526584","https://openalex.org/W3112294022","https://openalex.org/W3177684403","https://openalex.org/W3209659145","https://openalex.org/W3213506831","https://openalex.org/W4205938924","https://openalex.org/W6636698607","https://openalex.org/W6747938797"],"related_works":["https://openalex.org/W909270606","https://openalex.org/W2788402164","https://openalex.org/W2607951321","https://openalex.org/W1010277113","https://openalex.org/W3030532554","https://openalex.org/W2331818131","https://openalex.org/W1036923752","https://openalex.org/W4255909552","https://openalex.org/W2607845982","https://openalex.org/W975416911"],"abstract_inverted_index":{"Wnt\u548c\u6838\u56e0\u5b50-\u03baB(NF-\u03baB)\u4fe1\u53f7\u901a\u8def\u5206\u522b\u8c03\u63a7\u591a\u79cd\u529f\u80fd\u57fa\u56e0\u7684\u8f6c\u5f55,\u53c2\u4e0e\u8bb8\u591a\u91cd\u8981\u7684\u751f\u7406\u548c\u75c5\u7406\u8fc7\u7a0b,\u5728\u80bf\u7624\u53d1\u751f\u53d1\u5c55\u8fc7\u7a0b\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u89d2\u8272.\u8fd1\u6765\u53d1\u73b0Wnt\u548cNF-\u03baB\u4fe1\u53f7\u901a\u8def\u95f4\u8fd8\u5b58\u5728\u7740\u76f8\u4e92\u4f5c\u7528\u5373crosstalk,\u65e2\u8c03\u63a7\u5404\u4fe1\u53f7\u901a\u8def\u7ec4\u5206\u7684\u6d3b\u6027,\u53c8\u8c03\u63a7\u5171\u540c\u4e0b\u6e38\u9776\u57fa\u56e0\u53ca\u8868\u8fbe\u4ea7\u7269,\u7531\u6b64\u4fc3\u8fdb\u6216\u6291\u5236\u80bf\u7624\u7684\u53d1\u751f\u53d1\u5c55.":[0]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}