{"id":"https://openalex.org/W377526862","doi":"https://doi.org/10.3233/thc-1994-2207","title":"Cardiovascular responses to intrathoracic pressure variations in coronary disease patients: a computer simulation","display_name":"Cardiovascular responses to intrathoracic pressure variations in coronary disease patients: a computer simulation","publication_year":1994,"publication_date":"1994-07-01","ids":{"openalex":"https://openalex.org/W377526862","doi":"https://doi.org/10.3233/thc-1994-2207","mag":"377526862","pmid":"https://pubmed.ncbi.nlm.nih.gov/25273908"},"language":"en","primary_location":{"id":"doi:10.3233/thc-1994-2207","doi":"https://doi.org/10.3233/thc-1994-2207","is_oa":false,"landing_page_url":"https://doi.org/10.3233/thc-1994-2207","pdf_url":null,"source":{"id":"https://openalex.org/S2501230301","display_name":"Technology and Health Care","issn_l":"0928-7329","issn":["0928-7329","1878-7401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and Health Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072852317","display_name":"Montserrat Vallverd\u00fa","orcid":"https://orcid.org/0000-0002-2031-3261","observed_orcids":["https://orcid.org/0000-0002-2031-3261"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Montserrat Vallverd\u00fa","raw_affiliation_strings":["Institut de Cibern\u00e8tica, Universitat Polit\u00e8cnica de Catalunya \u2013 CSIC, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de Cibern\u00e8tica, Universitat Polit\u00e8cnica de Catalunya \u2013 CSIC, Barcelona, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I9617848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110207018","display_name":"Carles Crexells","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119948","display_name":"Hospital General de Catalunya","ror":"https://ror.org/02k4qm934","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210119948"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carles Crexells","raw_affiliation_strings":["Hospital General de Catalunya, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General de Catalunya, Barcelona, Spain","institution_ids":["https://openalex.org/I4210119948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065446322","display_name":"P. Caminal","orcid":"https://orcid.org/0000-0002-2301-8153","observed_orcids":["https://orcid.org/0000-0002-2301-8153"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pere Caminal","raw_affiliation_strings":["Institut de Cibern\u00e8tica, Universitat Polit\u00e8cnica de Catalunya \u2013 CSIC, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de Cibern\u00e8tica, Universitat Polit\u00e8cnica de Catalunya \u2013 CSIC, Barcelona, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I9617848"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5072852317"],"corresponding_institution_ids":["https://openalex.org/I134820265","https://openalex.org/I9617848"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.03753322,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2","issue":"2","first_page":"119","last_page":"140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.5015000104904175,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.5015000104904175,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.08839999884366989,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.05079999938607216,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/valsalva-maneuver","display_name":"Valsalva maneuver","score":0.9990000128746033},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.8769999742507935},{"id":"https://openalex.org/keywords/angina","display_name":"angina pectoris","score":0.8130000233650208},{"id":"https://openalex.org/keywords/intrathoracic-pressure","display_name":"intrathoracic pressure","score":0.871999979019165},{"id":"https://openalex.org/keywords/coronary-blood-flow","display_name":"coronary blood flow","score":0.7910000085830688},{"id":"https://openalex.org/keywords/cardiovascular-model","display_name":"cardiovascular system model","score":0.5199999809265137},{"id":"https://openalex.org/keywords/model-reduction","display_name":"model reduction","score":0.5659999847412109},{"id":"https://openalex.org/keywords/intra-abdominal-pressure","display_name":"intra-abdominal pressure","score":0.7879999876022339},{"id":"https://openalex.org/keywords/lethal-arrhythmia","display_name":"fatal arrhythmia","score":0.781000018119812}],"concepts":[{"id":"https://openalex.org/C2777517520","wikidata":"https://www.wikidata.org/wiki/Q1427231","display_name":"Valsalva maneuver","level":3,"score":0.7198472023010254},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7190833687782288},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6656750440597534},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.6008931994438171},{"id":"https://openalex.org/C2777385415","wikidata":"https://www.wikidata.org/wiki/Q1615191","display_name":"Cardiac catheterization","level":2,"score":0.5807254910469055},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5678991675376892},{"id":"https://openalex.org/C2778425758","wikidata":"https://www.wikidata.org/wiki/Q180762","display_name":"Angina","level":3,"score":0.5464694499969482},{"id":"https://openalex.org/C2777785093","wikidata":"https://www.wikidata.org/wiki/Q2032041","display_name":"Unstable angina","level":3,"score":0.43682968616485596},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3552677035331726},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.16169282793998718},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.11686855554580688}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3233/thc-1994-2207","doi":"https://doi.org/10.3233/thc-1994-2207","is_oa":false,"landing_page_url":"https://doi.org/10.3233/thc-1994-2207","pdf_url":null,"source":{"id":"https://openalex.org/S2501230301","display_name":"Technology and Health Care","issn_l":"0928-7329","issn":["0928-7329","1878-7401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and Health Care","raw_type":"journal-article"},{"id":"pmid:25273908","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25273908","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and health care : official journal of the European Society for Engineering and Medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W35866771","https://openalex.org/W1966919826","https://openalex.org/W1968277169","https://openalex.org/W1991485319","https://openalex.org/W1996842876","https://openalex.org/W1998186269","https://openalex.org/W2000780748","https://openalex.org/W2005197044","https://openalex.org/W2017340093","https://openalex.org/W2020778202","https://openalex.org/W2028954985","https://openalex.org/W2051920216","https://openalex.org/W2055103382","https://openalex.org/W2069501748","https://openalex.org/W2070352394","https://openalex.org/W2078132347","https://openalex.org/W2090704779","https://openalex.org/W2093830504","https://openalex.org/W2095802265","https://openalex.org/W2114342108","https://openalex.org/W2119229486","https://openalex.org/W2123428667","https://openalex.org/W2124136490","https://openalex.org/W2526790873","https://openalex.org/W3146777092"],"related_works":["https://openalex.org/W2060689785","https://openalex.org/W2061929022","https://openalex.org/W1991485319","https://openalex.org/W2146088310","https://openalex.org/W1599468550","https://openalex.org/W1971077596","https://openalex.org/W2543896113","https://openalex.org/W2011322472","https://openalex.org/W2051762479","https://openalex.org/W1995011047"],"abstract_inverted_index":{"Several":[0],"studies":[1,31],"have":[2,32,201],"suggested":[3,33],"that":[4,34,203],"the":[5,27,35,52,55,64,70,86,95,100,110,117,124,148,154,162,173,176,180,187,192,196,198,204,211,242],"Valsalva":[6,36,219],"maneuver":[7,21,37],"may":[8],"predispose":[9],"potential":[10],"lethal":[11],"arrhythmias":[12],"in":[13,106,129],"patients":[14,135,160],"with":[15,128,136],"coronary":[16,24,167,193],"artery":[17],"disease,":[18],"since":[19],"this":[20],"induces":[22],"diminished":[23],"flow.":[25],"On":[26],"other":[28],"hand":[29],"some":[30],"abruptly":[38],"reduces":[39],"determinants":[40],"of":[41,54,63,69,88,91,102,116,123,147,156,159,164,175,179,195,213],"cardiac":[42,143,149,239],"oxygen":[43,57,206],"demand,":[44],"relieving":[45],"angina":[46,139],"pectoris.":[47],"In":[48],"order":[49,107],"to":[50,81,94,108],"study":[51],"variations":[53,185],"myocardial":[56,205],"supply-demand":[58,207],"relation,":[59,208],"during":[60,142,210],"different":[61,166],"applications":[62],"maneuver,":[65],"a":[66,89,103],"mathematical":[67,96],"model":[68,77,97,105,125],"human":[71],"cardiovascular":[72,188],"system":[73],"is":[74],"presented.":[75],"The":[76,119,145],"has":[78,152,171],"been":[79],"submitted":[80],"an":[82],"evaluation":[83,146],"process":[84],"allowing":[85],"inclusion":[87],"number":[90],"additional":[92],"refinements":[93],"structures,":[98],"and":[99,113,182],"obtaining":[101],"reduced":[104],"improve":[109],"computer":[111],"time":[112],"parameter":[114],"estimation":[115],"simulation.":[118],"simulated":[120],"output":[121],"variables":[122],"correlate":[126],"well":[127],"vivo":[130],"data":[131,151],"obtained":[132],"from":[133],"ten":[134],"typical":[137],"exertional":[138],"pectoris":[140],"studied":[141],"catheterization.":[144],"catheterization":[150],"allowed":[153],"differentiation":[155],"two":[157,165,222],"subsets":[158],"by":[161],"identification":[163],"controllers.":[168],"Computer":[169],"simulation":[170,199,212],"permitted":[172],"analysis":[174],"relative":[177],"influences":[178],"intrathoracic":[181,215],"intraabdominal":[183],"pressure":[184],"on":[186,191,241],"variables.":[189],"Depending":[190],"control":[194],"patients,":[197],"results":[200,233],"shown":[202],"calculated":[209],"high":[214],"pressures,":[216],"long":[217],"duration":[218],"maneuvers,":[220,224],"or":[221,228,237],"consecutive":[223],"gets":[225],"values":[226],"higher":[227],"lower":[229],"than":[230],"unity.":[231],"These":[232],"suggest,":[234],"respectively,":[235],"beneficial":[236],"detrimental":[238],"effects":[240],"patients.":[243]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}