{"id":"https://openalex.org/W374344771","doi":null,"title":"Chromatin remodeling in the UV-induced DNA damage response","display_name":"Chromatin remodeling in the UV-induced DNA damage response","publication_year":2014,"publication_date":"2014-10-29","ids":{"openalex":"https://openalex.org/W374344771","mag":"374344771"},"language":"en","primary_location":{"id":"pmh:eur:oai:repub.eur.nl:77037","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/77037","pdf_url":"http://hdl.handle.net/1765/77037","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1765/77037","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082484551","display_name":"\u00d6zge Zelal Ayd\u0131n","orcid":"https://orcid.org/0000-0002-6181-8231","observed_orcids":["https://orcid.org/0000-0002-6181-8231"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"\u00d6zge Z. Aydin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6181-8231","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5082484551"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromatin-remodeling","display_name":"chromatin remodeling","score":0.9940000176429749},{"id":"https://openalex.org/keywords/dna-damage-response","display_name":"DNA damage response","score":0.9789999723434448},{"id":"https://openalex.org/keywords/uv-induced-dna-damage","display_name":"UV-induced DNA damage","score":0.8379999995231628},{"id":"https://openalex.org/keywords/nucleotide-excision-repair","display_name":"nucleotide excision repair","score":0.9879999756813049},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.8309999704360962},{"id":"https://openalex.org/keywords/chromatin-accessibility","display_name":"chromatin accessibility","score":0.6489999890327454},{"id":"https://openalex.org/keywords/dna-repair-signaling","display_name":"DNA repair signaling","score":0.6740000247955322},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.8266214728355408},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.7307085394859314},{"id":"https://openalex.org/C104451858","wikidata":"https://www.wikidata.org/wiki/Q2714458","display_name":"Nucleotide excision repair","level":4,"score":0.6678131818771362},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.6430984139442444},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6426388025283813},{"id":"https://openalex.org/C167227067","wikidata":"https://www.wikidata.org/wiki/Q5113739","display_name":"Chromatin remodeling","level":4,"score":0.6386149525642395},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5802935361862183},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.472968727350235},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37415361404418945}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:eur:oai:repub.eur.nl:77037","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/77037","pdf_url":"http://hdl.handle.net/1765/77037","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:oai:repub.eur.nl:77037","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/77037","pdf_url":"http://repub.eur.nl/pub/77037","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:eur:oai:pure.eur.nl:publications/528c9c85-d6d0-4786-9a5b-59313267beec","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/528c9c85-d6d0-4786-9a5b-59313267beec","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:374344771","doi":null,"is_oa":false,"landing_page_url":"https://repub.eur.nl/pub/77037/141029_Aydin-Ozge-Zelal-BEWERKT.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:eur:oai:repub.eur.nl:77037","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/77037","pdf_url":"http://hdl.handle.net/1765/77037","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2301641199","display_name":null,"funder_award_id":"912.12.132","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G6143296615","display_name":"Excision Repair and chromatin interaction dynamics","funder_award_id":"340988","funder_id":"https://openalex.org/F4320338352","funder_display_name":"FP7 Ideas: European Research Council"},{"id":"https://openalex.org/G774254162","display_name":null,"funder_award_id":"854.11.002","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"}],"funders":[{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"},{"id":"https://openalex.org/F4320338352","display_name":"FP7 Ideas: European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W374344771.pdf","grobid_xml":"https://content.openalex.org/works/W374344771.grobid-xml"},"referenced_works_count":255,"referenced_works":["https://openalex.org/W1591356060","https://openalex.org/W1660332899","https://openalex.org/W1717645955","https://openalex.org/W1752089945","https://openalex.org/W1760824447","https://openalex.org/W1944127002","https://openalex.org/W1956982520","https://openalex.org/W1963650107","https://openalex.org/W1964318436","https://openalex.org/W1964370576","https://openalex.org/W1965531809","https://openalex.org/W1966805664","https://openalex.org/W1966809971","https://openalex.org/W1968073368","https://openalex.org/W1969150779","https://openalex.org/W1969175894","https://openalex.org/W1970989361","https://openalex.org/W1973030224","https://openalex.org/W1974625077","https://openalex.org/W1974667981","https://openalex.org/W1974755980","https://openalex.org/W1974795717","https://openalex.org/W1975141727","https://openalex.org/W1976242374","https://openalex.org/W1978780879","https://openalex.org/W1979417055","https://openalex.org/W1979540894","https://openalex.org/W1980745500","https://openalex.org/W1980887180","https://openalex.org/W1981565987","https://openalex.org/W1982602899","https://openalex.org/W1982657419","https://openalex.org/W1983084308","https://openalex.org/W1983728990","https://openalex.org/W1985157244","https://openalex.org/W1985444222","https://openalex.org/W1985775217","https://openalex.org/W1987128123","https://openalex.org/W1987849582","https://openalex.org/W1988313137","https://openalex.org/W1989208996","https://openalex.org/W1989325752","https://openalex.org/W1989340932","https://openalex.org/W1989540020","https://openalex.org/W1989968124","https://openalex.org/W1990586926","https://openalex.org/W1992273348","https://openalex.org/W1992290890","https://openalex.org/W1995569417","https://openalex.org/W1995842607","https://openalex.org/W1995987769","https://openalex.org/W1996516839","https://openalex.org/W1997303368","https://openalex.org/W1998499862","https://openalex.org/W1999940145","https://openalex.org/W2001761725","https://openalex.org/W2002167083","https://openalex.org/W2002421203","https://openalex.org/W2002934916","https://openalex.org/W2005262749","https://openalex.org/W2005560276","https://openalex.org/W2007839434","https://openalex.org/W2008185037","https://openalex.org/W2011958170","https://openalex.org/W2012064508","https://openalex.org/W2012671266","https://openalex.org/W2013427348","https://openalex.org/W2013826273","https://openalex.org/W2013970469","https://openalex.org/W2016625616","https://openalex.org/W2016861729","https://openalex.org/W2016991737","https://openalex.org/W2019292967","https://openalex.org/W2021026930","https://openalex.org/W2021044341","https://openalex.org/W2021292600","https://openalex.org/W2021606478","https://openalex.org/W2021816070","https://openalex.org/W2022093187","https://openalex.org/W2022439334","https://openalex.org/W2024946505","https://openalex.org/W2025209634","https://openalex.org/W2025882515","https://openalex.org/W2027111177","https://openalex.org/W2027631710","https://openalex.org/W2028604413","https://openalex.org/W2029052089","https://openalex.org/W2030073462","https://openalex.org/W2030105789","https://openalex.org/W2030475136","https://openalex.org/W2030748126","https://openalex.org/W2030851477","https://openalex.org/W2031468663","https://openalex.org/W2031884770","https://openalex.org/W2032206017","https://openalex.org/W2032471242","https://openalex.org/W2032739040","https://openalex.org/W2033666481","https://openalex.org/W2034195501","https://openalex.org/W2034340491","https://openalex.org/W2034844603","https://openalex.org/W2036239925","https://openalex.org/W2036907121","https://openalex.org/W2037936898","https://openalex.org/W2037951413","https://openalex.org/W2039107445","https://openalex.org/W2039597909","https://openalex.org/W2040730809","https://openalex.org/W2041613483","https://openalex.org/W2043148368","https://openalex.org/W2043776245","https://openalex.org/W2043895957","https://openalex.org/W2044385397","https://openalex.org/W2044876560","https://openalex.org/W2045775784","https://openalex.org/W2046082575","https://openalex.org/W2046147149","https://openalex.org/W2047664934","https://openalex.org/W2050570838","https://openalex.org/W2051029106","https://openalex.org/W2051514283","https://openalex.org/W2051801459","https://openalex.org/W2052777526","https://openalex.org/W2052816402","https://openalex.org/W2052978365","https://openalex.org/W2053437887","https://openalex.org/W2054782539","https://openalex.org/W2055097137","https://openalex.org/W2055373932","https://openalex.org/W2055501242","https://openalex.org/W2056768631","https://openalex.org/W2057545775","https://openalex.org/W2058101616","https://openalex.org/W2059344501","https://openalex.org/W2060289784","https://openalex.org/W2061304668","https://openalex.org/W2065125915","https://openalex.org/W2068533511","https://openalex.org/W2068973408","https://openalex.org/W2069067882","https://openalex.org/W2069328568","https://openalex.org/W2070821144","https://openalex.org/W2072007776","https://openalex.org/W2072607093","https://openalex.org/W2074536099","https://openalex.org/W2076316122","https://openalex.org/W2077630337","https://openalex.org/W2078544177","https://openalex.org/W2079647703","https://openalex.org/W2079743290","https://openalex.org/W2080148998","https://openalex.org/W2080199752","https://openalex.org/W2080747531","https://openalex.org/W2081032844","https://openalex.org/W2082139407","https://openalex.org/W2082701826","https://openalex.org/W2083022228","https://openalex.org/W2083555350","https://openalex.org/W2084369408","https://openalex.org/W2084908485","https://openalex.org/W2084969545","https://openalex.org/W2086369200","https://openalex.org/W2086445866","https://openalex.org/W2087366808","https://openalex.org/W2089263351","https://openalex.org/W2089814375","https://openalex.org/W2091389464","https://openalex.org/W2092104135","https://openalex.org/W2093012141","https://openalex.org/W2096083625","https://openalex.org/W2096540333","https://openalex.org/W2096596194","https://openalex.org/W2096731080","https://openalex.org/W2097124161","https://openalex.org/W2097451573","https://openalex.org/W2098387013","https://openalex.org/W2100871132","https://openalex.org/W2101923550","https://openalex.org/W2102273403","https://openalex.org/W2104123741","https://openalex.org/W2104629556","https://openalex.org/W2104864650","https://openalex.org/W2104911291","https://openalex.org/W2104968595","https://openalex.org/W2106220910","https://openalex.org/W2106778040","https://openalex.org/W2107043033","https://openalex.org/W2107747328","https://openalex.org/W2107981920","https://openalex.org/W2108192712","https://openalex.org/W2112090753","https://openalex.org/W2112331024","https://openalex.org/W2112348939","https://openalex.org/W2113613985","https://openalex.org/W2114776482","https://openalex.org/W2115123726","https://openalex.org/W2115852070","https://openalex.org/W2121909403","https://openalex.org/W2123678649","https://openalex.org/W2124837740","https://openalex.org/W2124938253","https://openalex.org/W2125321557","https://openalex.org/W2126779104","https://openalex.org/W2127956308","https://openalex.org/W2128569634","https://openalex.org/W2129361946","https://openalex.org/W2129378146","https://openalex.org/W2130027970","https://openalex.org/W2131415510","https://openalex.org/W2131497564","https://openalex.org/W2131827278","https://openalex.org/W2132057054","https://openalex.org/W2133406008","https://openalex.org/W2134071049","https://openalex.org/W2134767256","https://openalex.org/W2135715308","https://openalex.org/W2136582666","https://openalex.org/W2136785472","https://openalex.org/W2137568452","https://openalex.org/W2139777089","https://openalex.org/W2139873559","https://openalex.org/W2140549234","https://openalex.org/W2140946052","https://openalex.org/W2141451936","https://openalex.org/W2141991853","https://openalex.org/W2144484738","https://openalex.org/W2144793849","https://openalex.org/W2145200068","https://openalex.org/W2145809931","https://openalex.org/W2145863517","https://openalex.org/W2148120557","https://openalex.org/W2150100825","https://openalex.org/W2150322921","https://openalex.org/W2152645308","https://openalex.org/W2153759298","https://openalex.org/W2154457034","https://openalex.org/W2155420844","https://openalex.org/W2156970346","https://openalex.org/W2157963865","https://openalex.org/W2158217645","https://openalex.org/W2162365619","https://openalex.org/W2162951729","https://openalex.org/W2164995160","https://openalex.org/W2165125584","https://openalex.org/W2165912346","https://openalex.org/W2167284666","https://openalex.org/W2167844024","https://openalex.org/W2168268248","https://openalex.org/W2168303063","https://openalex.org/W2169509924","https://openalex.org/W2169741450","https://openalex.org/W2171630274","https://openalex.org/W2198199336","https://openalex.org/W2320477999","https://openalex.org/W2329719572"],"related_works":["https://openalex.org/W2137479265","https://openalex.org/W2743728950","https://openalex.org/W2774065859","https://openalex.org/W7217113939","https://openalex.org/W2000218210","https://openalex.org/W2060095336","https://openalex.org/W1531628318","https://openalex.org/W4379930708","https://openalex.org/W1964922169","https://openalex.org/W2114088347"],"abstract_inverted_index":{"__Abstract__":[0],"DNA":[1,26,33,42,55,78,99],"damage":[2,43],"interferes":[3],"with":[4],"transcription":[5],"and":[6,19,35,57,79,111],"replication,":[7],"causing":[8],"cell":[9],"death,":[10],"chromosomal":[11],"aberrations":[12],"or":[13],"mutations,":[14],"eventually":[15],"leading":[16],"to":[17,71,77,82,85],"aging":[18],"tumorigenesis":[20],"(Hoeijmakers,":[21],"2009).":[22,49],"The":[23,115],"integrity":[24],"of":[25,32,74,128],"is":[27,69,123],"protected":[28],"by":[29,101],"a":[30,52,61],"network":[31],"repair":[34,56,75,100],"associated":[36],"signalling":[37,103],"pathways,":[38],"collectively":[39],"called":[40],"the":[41,126,134],"response":[44],"(DDR)":[45],"(Jackson":[46],"&":[47],"Bartek,":[48],"Chromatin":[50,68,90],"poses":[51],"barrier":[53],"for":[54,98,108],"as":[58,93],"such":[59],"plays":[60],"critical":[62],"role":[63,127],"in":[64,120,131],"controlling":[65,112],"DDR":[66],"efficiency.":[67],"modified":[70],"regulate":[72],"access":[73],"proteins":[76,110],"needs":[80],"also":[81,91],"be":[83],"restored":[84],"its":[86],"original":[87],"configuration":[88],"afterwards.":[89],"serves":[92],"an":[94],"optimal":[95],"regulation":[96],"platform":[97],"mediating":[102],"events,":[104],"providing":[105],"docking":[106],"sites":[107],"signaling":[109],"their":[113],"activity.":[114],"work":[116],"that":[117],"we":[118],"describe":[119],"this":[121],"thesis":[122],"focused":[124],"on":[125],"chromatin":[129],"remodelling":[130],"DDR,":[132],"specifically":[133],"Nucleotide":[135],"Excision":[136],"Repair":[137],"(NER)":[138],"pathway.":[139]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}