{"id":"https://openalex.org/W37022538","doi":null,"title":"Uptake and effects of nanoparticles in fish","display_name":"Uptake and effects of nanoparticles in fish","publication_year":2009,"publication_date":"2009-09-25","ids":{"openalex":"https://openalex.org/W37022538","mag":"37022538"},"language":"en","primary_location":{"id":"pmh:oai:ore.exeter.ac.uk:10036/93696","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10036/93696","pdf_url":"http://hdl.handle.net/10036/93696","source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10036/93696","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071626186","display_name":"Tessa M. Scown","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Tessa M. Scown","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5071626186"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.8848000168800354,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.8848000168800354,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.11289999634027481,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10753","display_name":"Microplastics and Plastic Pollution","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/engineered-nanomaterials","display_name":"engineered nanomaterials","score":0.9070000052452087},{"id":"https://openalex.org/keywords/fish","display_name":"fish","score":0.5090000033378601},{"id":"https://openalex.org/keywords/rainbow-trout","display_name":"rainbow trout","score":0.9810000061988831},{"id":"https://openalex.org/keywords/titanium-dioxide-nanoparticles","display_name":"titanium dioxide nanoparticles","score":0.9589999914169312},{"id":"https://openalex.org/keywords/silver-nanoparticles","display_name":"silver nanoparticles","score":0.9890000224113464},{"id":"https://openalex.org/keywords/metal-oxide-nanoparticles","display_name":"metal oxide nanoparticles","score":0.734000027179718},{"id":"https://openalex.org/keywords/nanoparticle-uptake","display_name":"nanoparticle uptake","score":0.7670000195503235},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.9229999780654907},{"id":"https://openalex.org/keywords/gill-uptake","display_name":"gill uptake","score":0.578000009059906},{"id":"https://openalex.org/keywords/dietary-exposure","display_name":"dietary exposure","score":0.5820000171661377},{"id":"https://openalex.org/keywords/intravenous-injection","display_name":"intravenous injection","score":0.9039999842643738},{"id":"https://openalex.org/keywords/kidney-retention","display_name":"kidney retention","score":0.6100000143051147},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6110000014305115},{"id":"https://openalex.org/keywords/metallothionein","display_name":"metallothionein","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.6618669629096985},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.5495839715003967},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.389516144990921},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33704647421836853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32866621017456055},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32606226205825806},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.321402370929718},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.21417191624641418}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:ore.exeter.ac.uk:10036/93696","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10036/93696","pdf_url":"http://hdl.handle.net/10036/93696","source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or dissertation"},{"id":"pmh:hdl:10068/989759","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/989759","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"pmh:oai:figshare.com:article/29693069","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Uptake_and_Effects_of_Nanoparticles_in_Fish/29693069","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:uilis.unsyiah.ac.id:11508","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10036/93696","pdf_url":null,"source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis or dissertation"},{"id":"mag:37022538","doi":null,"is_oa":false,"landing_page_url":"https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547129","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ore.exeter.ac.uk:10036/93696","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10036/93696","pdf_url":"http://hdl.handle.net/10036/93696","source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or dissertation"},"sustainable_development_goals":[{"score":0.7778000235557556,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W37022538.pdf","grobid_xml":"https://content.openalex.org/works/W37022538.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W2056008081","https://openalex.org/W2114882618","https://openalex.org/W2336828812","https://openalex.org/W2911163036","https://openalex.org/W4282548904","https://openalex.org/W4316362867","https://openalex.org/W6804626565"],"related_works":["https://openalex.org/W791148093","https://openalex.org/W7098622300","https://openalex.org/W2153832339","https://openalex.org/W2029072568","https://openalex.org/W3201953477","https://openalex.org/W2073100513","https://openalex.org/W2062260299","https://openalex.org/W4309748734","https://openalex.org/W2041597451","https://openalex.org/W1964123007"],"abstract_inverted_index":{"Nanotechnology":[0],"is":[1,64,74,298],"a":[2,112,123,130,273,364,451,459,479,544,583],"rapidly":[3],"growing":[4,295],"industry":[5],"of":[6,17,39,68,111,114,133,138,192,198,214,223,225,275,305,308,343,350,357,381,400,404,442,458,461,472,482,532,553,557,561,589,606,617,619],"global":[7],"economic":[8],"importance,":[9],"with":[10,360,369,373],"new":[11],"technologies":[12],"exploiting":[13],"the":[14,21,28,59,109,134,160,174,196,215,218,229,249,302,306,338,353,385,417,440,494,525,530,537,549,562,565,600,604,615],"novel":[15],"characteristics":[16],"materials":[18],"manufactured":[19],"at":[20,66,341],"nanoscale":[22],"being":[23],"developed":[24],"for":[25,251,289,367,438,454,469,517,547,586],"use":[26,271,307],"within":[27],"biomedical,":[29],"electronic,":[30],"energy":[31],"production":[32,490],"and":[33,116,136,152,164,168,177,182,202,245,286,331,345,355,468,514,520,626,631],"environmental":[34,303],"sectors.":[35],"The":[36,61,98,476,498,593],"unusual":[37],"properties":[38],"engineered":[40],"nanomaterials":[41],"(ENMs)":[42],"that":[43,100,576],"make":[44],"them":[45],"useful":[46,584],"in":[47,81,140,248,269,272,311,352,377,384,389,394,409,416,422,434,455,464,491,536,555,578,596,608,621,628,632],"such":[48,278],"applications":[49],"have":[50],"led":[51],"to":[52,70,86,107,128,148,169,207,217,253,316,326,411,428,466,493,507,529],"concerns":[53],"regarding":[54,603],"their":[55,79,84,94,290,623],"potential":[56,95,319,452,550],"impact":[57],"on":[58,260,505],"environment.":[60],"aquatic":[62,82,91,609,629],"environment":[63],"particularly":[65],"risk":[67],"exposure":[69,204,506],"ENPs,":[71],"yet,":[72],"there":[73,297],"currently":[75],"little":[76,299],"known":[77,300],"about":[78,301],"behaviour":[80],"systems,":[83],"capacity":[85],"be":[87,208],"taken":[88],"up":[89,252],"by":[90,488,570],"organisms":[92],"or":[93,397],"toxic":[96,551],"effects.":[97],"studies":[99,594],"were":[101,146,233,323,392,527],"conducted":[102,595],"during":[103],"this":[104,577,597],"work":[105],"sought":[106],"investigate":[108,317],"ecotoxicology":[110],"range":[113,460],"metal":[115,117],"oxide":[118,513],"nanoparticles":[119,172,216,266,362,467,473,516,563],"using":[120,235],"fish":[121],"as":[122,279,450,486,611,613],"vertebrate":[124],"model.":[125],"In":[126,314,425],"order":[127,315],"gain":[129],"better":[131],"understanding":[132,622],"uptake":[135,224,378,471,588,625],"effects":[137,304,552,627],"ENMs":[139,554],"fish,":[141,219],"rainbow":[142,321,444],"trout":[143,199,322,358,445],"(Oncorhynchus":[144],"mykiss)":[145],"exposed":[147,325],"nanoparticulate":[149,309],"(34":[150],"nm)":[151,155],"bulk":[153,332],"(>100":[154],"titanium":[156,170,193,226,242,508],"dioxide":[157,171,194,227,243],"particles":[158,336,380,415],"via":[159,173,183,337],"water":[161,339],"column":[162,340],"(500":[163],"5000":[165],"\u00b5g":[166,347],"L-1),":[167],"diet":[175],"(0.1":[176],"1":[178],"mg":[179,187],"g-1":[180],"food)":[181],"intravenous":[184],"injection":[185],"(1.3":[186],"kg-1":[188],"body":[189],"weight).":[190],"Uptake":[191,349,560],"into":[195,474,564,591],"tissues":[197],"after":[200,484],"waterborne":[201],"dietary":[203],"was":[205,246,263,406,448,568],"found":[206],"very":[209],"low,":[210],"suggesting":[211,419,540],"limited":[212,503],"bioavailability":[213,605],"although":[220],"small":[221],"amounts":[222],"across":[228],"gill":[230,370],"epithelial":[231],"membrane":[232],"observed":[234],"coherent":[236,571],"anti-stokes":[237,572],"Raman":[238,573],"scattering.":[239],"Intravenously":[240],"injected":[241],"accumulated":[244],"retained":[247,478],"kidneys":[250],"21":[254],"days,":[255],"but":[256,372],"no":[257,374],"adverse":[258],"effect":[259],"kidney":[261],"function":[262],"detected.":[264],"Silver":[265],"are":[267,542],"already":[268],"widespread":[270],"variety":[274],"consumer":[276],"products":[277],"wound":[280],"dressings,":[281],"food":[282],"containers,":[283],"sock":[284],"fabrics":[285],"paints,":[287],"principally":[288],"antimicrobial":[291],"activity.":[292],"Despite":[293],"its":[294],"commercialisation,":[296],"silver":[310,335,351,414,515],"these":[312,318,533,558],"products.":[313],"effects,":[320],"also":[324],"10":[327,344,412],"nm,":[328],"35":[329],"nm":[330,413],"(0.6-1.6":[333],"\u00b5m)":[334],"concentration":[342],"100":[346],"L-1.":[348],"gills":[354],"liver":[356,396],"occurred,":[359],"smaller":[361],"showing":[363],"greater":[365],"propensity":[366],"association":[368],"tissue,":[371],"significant":[375],"differences":[376],"between":[379],"different":[382],"sizes":[383],"liver.":[386],"No":[387],"increases":[388],"lipid":[390,518],"peroxidation":[391,519],"detected":[393],"gills,":[395],"blood":[398],"plasma":[399],"trout,":[401],"however,":[402,501,567],"expression":[403],"cyp1a2":[405],"significantly":[407],"up-regulated":[408],"exposures":[410],"gill,":[418],"an":[420,426,430],"increase":[421],"oxidative":[423],"metabolism.":[424],"attempt":[427],"develop":[429],"effective":[431],"high":[432],"through-put":[433],"vitro":[435,456,579],"screening":[436,457],"assay":[437,580],"ENMs,":[439],"suitability":[441],"isolated":[443],"primary":[446],"hepatocytes":[447,477,526],"examined":[449],"model":[453,546,585],"toxicological":[462],"endpoints":[463],"response":[465,492],"studying":[470,587],"cells.":[475,592],"good":[480,545],"level":[481],"functionality":[483],"culturing":[485],"evidenced":[487],"vitellogenin":[489],"synthetic":[495],"oestrogen,":[496],"17\u03b2-oestradiol.":[497],"cultured":[499],"hepatocytes,":[500],"showed":[502],"responses":[504,535],"dioxide,":[509],"zinc":[510],"oxide,":[511],"cerium":[512],"glutathione-s-transferase":[521],"activity":[522],"assays.":[523],"Furthermore,":[524],"unresponsive":[528],"induction":[531],"biological":[534],"positive":[538],"controls,":[539],"they":[541],"not":[543],"investigating":[548],"terms":[556],"endpoints.":[559],"cells,":[566],"demonstrated":[569],"spectroscopy,":[574],"indicating":[575],"may":[581],"provide":[582],"ENPs":[590,607,620],"thesis":[598],"contribute":[599],"science":[601],"base":[602],"media":[610],"well":[612],"highlighting":[614],"importance":[616],"characterisation":[618],"behaviour,":[624],"systems":[630],"fish.":[633]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}
