{"id":"https://openalex.org/W37016645","doi":"https://doi.org/10.2450/2013.018s","title":"Plasma and plasma-derived medicinal product self-sufficiency: the Italian case.","display_name":"Plasma and plasma-derived medicinal product self-sufficiency: the Italian case.","publication_year":2013,"publication_date":"2013-09-01","ids":{"openalex":"https://openalex.org/W37016645","doi":"https://doi.org/10.2450/2013.018s","mag":"37016645","pmid":"https://pubmed.ncbi.nlm.nih.gov/24333304","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2843576","doi":"https://doi.org/10.2450/2013.018s","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108110025","display_name":"Gabriele Calizzani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gabriele Calizzani","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053132960","display_name":"Samantha Profili","orcid":"https://orcid.org/0000-0002-5159-1248","observed_orcids":["https://orcid.org/0000-0002-5159-1248"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Samantha Profili","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011299007","display_name":"Fabio Candura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Candura","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068724047","display_name":"Monica Lanzoni","orcid":"https://orcid.org/0000-0003-4058-6280","observed_orcids":["https://orcid.org/0000-0003-4058-6280"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Monica Lanzoni","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy IRCCS Ca' Granda Foundation Maggiore Policlinico Hospital, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy IRCCS Ca' Granda Foundation Maggiore Policlinico Hospital, Milan, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I2803066834","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065998483","display_name":"Stefania Vaglio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefania Vaglio","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy Faculty of Medicine and Psychology, \"Sapienza\" University of Rome, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy Faculty of Medicine and Psychology, \"Sapienza\" University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958","https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014917775","display_name":"Livia Cannata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Livia Cannata","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045636723","display_name":"Liviana Catalano","orcid":"https://orcid.org/0000-0003-4144-9974","observed_orcids":["https://orcid.org/0000-0003-4144-9974"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Liviana Catalano","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081711395","display_name":"Rosa Chianese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109922","display_name":"Ospedale Civile Di Ivrea","ror":"https://ror.org/01nsxt963","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210109922"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosa Chianese","raw_affiliation_strings":["Piedmont Regional Blood Centre at Transfusion Medicine and Haematology Unit, Ivrea Hospital, Ivrea, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Piedmont Regional Blood Centre at Transfusion Medicine and Haematology Unit, Ivrea Hospital, Ivrea, Italy","institution_ids":["https://openalex.org/I4210109922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109519031","display_name":"Giancarlo Maria Liumbruno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108212","display_name":"Fatebenefratelli Hospital","ror":"https://ror.org/01x9zv505","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210108212","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giancarlo M Liumbruno","raw_affiliation_strings":["Immunohaematology, Medicine and Clinical Pathology Units, \"San Giovanni Calibita\" Fatebenefratelli Hospital, AFAR, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunohaematology, Medicine and Clinical Pathology Units, \"San Giovanni Calibita\" Fatebenefratelli Hospital, AFAR, Rome, Italy","institution_ids":["https://openalex.org/I4210108212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006430006","display_name":"Giuliano Grazzini","orcid":"https://orcid.org/0000-0002-9865-6969","observed_orcids":["https://orcid.org/0000-0002-9865-6969"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I4405268958","display_name":"Centro Nazionale Sangue","ror":"https://ror.org/02kxn5h20","country_code":"IT","type":"government","lineage":["https://openalex.org/I4405268958"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuliano Grazzini","raw_affiliation_strings":["Italian National Blood Centre, National Institute of Health, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian National Blood Centre, National Institute of Health, Rome, Italy","institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4405268958"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.893,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.9125778,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"11 Suppl 4","issue":null,"first_page":"s118","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.4625999927520752,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.4625999927520752,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.14249999821186066,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T14293","display_name":"Biotechnology and Related Fields","score":0.04500000178813934,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasma-derived-products","display_name":"plasma-derived products","score":0.9419999718666077},{"id":"https://openalex.org/keywords/plasma-supply","display_name":"plasma supply","score":0.5759999752044678},{"id":"https://openalex.org/keywords/plasma-collection","display_name":"plasma collection","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C2778958867","wikidata":"https://www.wikidata.org/wiki/Q2571972","display_name":"Decree","level":2,"score":0.5868909955024719},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.5661473870277405},{"id":"https://openalex.org/C83009810","wikidata":"https://www.wikidata.org/wiki/Q11204","display_name":"Legislature","level":2,"score":0.5603771805763245},{"id":"https://openalex.org/C98147612","wikidata":"https://www.wikidata.org/wiki/Q215599","display_name":"Promotion (chess)","level":3,"score":0.5463999509811401},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.5279131531715393},{"id":"https://openalex.org/C2780378061","wikidata":"https://www.wikidata.org/wiki/Q25351891","display_name":"Service (business)","level":2,"score":0.5082809329032898},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.43624791502952576},{"id":"https://openalex.org/C2775933685","wikidata":"https://www.wikidata.org/wiki/Q1124860","display_name":"Donation","level":2,"score":0.42980867624282837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38591468334198},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.3304089605808258},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.24467217922210693},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.2354680597782135},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.1714680790901184},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.11384090781211853},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.08833593130111694},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.08391451835632324},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000600","qualifier_name":"supply & distribution","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010949","descriptor_name":"Plasma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:2843576","doi":"https://doi.org/10.2450/2013.018s","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3853989","doi":"https://doi.org/10.2450/2013.018s","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Transfus","raw_type":"Text"},{"id":"pmid:24333304","doi":"https://doi.org/10.2450/2013.018s","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24333304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood transfusion = Trasfusione del sangue","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/673233","doi":"https://doi.org/10.2450/2013.018s","is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/673233","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:37016645","doi":"https://doi.org/10.2450/2013.018s","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24333304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2843576","doi":"https://doi.org/10.2450/2013.018s","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3853989","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/17","score":0.5600000023841858,"display_name":"Partnerships for the goals"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W41274749","https://openalex.org/W65994323","https://openalex.org/W81601922","https://openalex.org/W89057783","https://openalex.org/W108792333","https://openalex.org/W141440949","https://openalex.org/W167101917","https://openalex.org/W174346752","https://openalex.org/W264886780","https://openalex.org/W273677280","https://openalex.org/W301694005","https://openalex.org/W1425259512","https://openalex.org/W1556812677","https://openalex.org/W1577702032","https://openalex.org/W1584790781","https://openalex.org/W1858663466","https://openalex.org/W1965747253","https://openalex.org/W1966569531","https://openalex.org/W2004189392","https://openalex.org/W2024630021","https://openalex.org/W2048099106","https://openalex.org/W2058184168","https://openalex.org/W2063592917","https://openalex.org/W2085027388","https://openalex.org/W2186844863","https://openalex.org/W2295028658","https://openalex.org/W2408470109"],"related_works":["https://openalex.org/W1425259512","https://openalex.org/W6959970308","https://openalex.org/W2138831212","https://openalex.org/W2966487709","https://openalex.org/W314338340","https://openalex.org/W2137189715","https://openalex.org/W7014392217","https://openalex.org/W1555643057","https://openalex.org/W2914651951","https://openalex.org/W6991756107"],"abstract_inverted_index":{"According":[0],"to":[1,55,117,149,159,201,262,277,305,378,434],"the":[2,22,36,39,84,102,124,141,150,153,164,213,216,231,270,288,291,303,309,344,357,367,374,380,390,396,408,413,430,436],"World":[3],"Health":[4,41,143,167],"Organization,":[5],"\u201cself-sufficiency":[6],"in":[7,46,221,267,426,441,443],"safe":[8,28],"blood":[9,11,17,29,31,59,96,103,222,225,274,376],"and":[10,30,58,61,71,112,196,224,236,252,256,336,355,373,402,419],"products":[12,64,91,387],"based":[13],"on":[14,366],"voluntary":[15],"non-remunerated":[16,253],"donation":[18],"(VNRBD)":[19],"means":[20],"that":[21,50,62],"national":[23,174,244,375,393],"needs":[24,384],"of":[25,38,69,74,86,88,101,110,114,134,140,152,166,218,233,239,343,352,356,369,382,392,417,420,429,438],"patients":[26,51],"for":[27,170,176,211,215,347],"products,":[32,60],"as":[33,78,93,95,120,131,228,230,263,349,351],"assessed":[34],"within":[35,395],"framework":[37],"National":[40,142],"Service":[42],"(NHS),":[43],"are":[44,65],"met":[45],"a":[47,99,132,205,296,423],"timely":[48],"manner,":[49],"have":[52],"equitable":[53],"access":[54],"transfusion":[56,115],"services":[57,223],"these":[63],"obtained":[66,388],"from":[67,79,247,407],"VNRBD":[68],"national,":[70],"where":[72],"needed,":[73],"regional":[75,154,370],"origin,":[76],"such":[77],"neighbouring":[80],"countries\u201d1.":[81],"In":[82,157],"Italy,":[83],"achievement":[85,146],"self-sufficiency":[87,177,363,440],"plasma-derived":[89,240,322,327],"medicinal":[90,241],"(PMPs),":[92],"well":[94,229,350],"components,":[97],"is":[98,129,147,168,290,433],"goal":[100],"system":[104,190,377],"\u201caimed":[105],"at":[106,179,287,307],"guaranteeing":[107],"equal":[108],"conditions":[109],"quality":[111],"safety":[113],"therapy":[116],"all":[118,386],"citizens\u201d,":[119],"set":[121],"out":[122],"by":[123,273,389],"main":[125],"regulatory":[126],"reference2.":[127],"Self-sufficiency":[128],"recognised":[130],"role":[133,425],"\u201cnational,":[135],"supra-regional,":[136],"supra-local":[137],"indivisible":[138],"interest":[139],"Service\u201d":[144],"whose":[145],"entrusted":[148],"contributions":[151],"health":[155,371],"authorities.":[156],"order":[158],"attain":[160],"this":[161],"strategic":[162],"goal,":[163],"Ministry":[165],"responsible":[169],"defining":[171,212],"an":[172,234],"annual":[173],"programme":[175],"aimed":[178],"identifying":[180],"historical":[181],"usages,":[182],"real":[183],"demand,":[184],"necessary":[185],"production":[186],"levels,":[187],"resources,":[188],"funding":[189],"criteria,":[191],"interregional":[192],"PMP":[193],"exchanges,":[194],"import":[195],"export":[197],"levels3\u20135.":[198],"Moreover,":[199],"according":[200],"current":[202],"legislative":[203],"provisions6,7,":[204],"special":[206],"decree":[207],"must":[208],"be":[209],"adopted":[210],"\u201cprogram":[214],"development":[217],"plasma":[219,245,271,345,394],"collection":[220,226],"units,":[227],"promotion":[232],"appropriate":[235,414],"rational":[237],"use":[238,416],"products\u201d.\r\n\r\nIn":[242],"addition,":[243],"derives":[246],"voluntary,":[248],"periodic,":[249],"responsible,":[250],"anonymous":[251],"donations2.":[254],"Regions":[255,340,401],"Autonomous":[257],"Provinces":[258],"(APs)":[259],"(henceforth":[260],"referred":[261],"\u201cRegions\u201d),":[264],"individually":[265],"or":[266],"association,":[268],"send":[269],"collected":[272],"establishments":[275],"(BE)":[276],"Kedrion":[278],"Biopharma":[279],"(Kedrion":[280],"SpA,":[281],"Castelvecchio":[282],"Pascoli,":[283],"Lucca,":[284],"Italy),":[285],"which,":[286],"moment,":[289],"only":[292],"manufacturer":[293],"authorised":[294],"under":[295],"toll":[297,397],"fractionation":[298,398],"agreement.":[299],"The":[300],"latter":[301],"has":[302],"capacity":[304,368],"produce":[306],"least":[308],"following":[310],"PMPs:":[311],"human":[312],"albumin":[313],"solution":[314],"(albumin),":[315],"polyvalent":[316],"immunoglobulin":[317],"(for":[318],"intravascular":[319],"administration,":[320],"IVIG),":[321],"factor":[323,328],"VIII":[324],"concentrates":[325,330,334],"(pdFVIII),":[326],"IX":[329],"(pdFIX),":[331],"prothrombin":[332],"complex":[333],"(PCCs),":[335],"antithrombin":[337],"(AT).":[338],"However,":[339,411],"remain":[341],"owners":[342],"sent":[346],"fractionation,":[348],"PMPs":[353,421,439],"manufactured":[354],"residual":[358],"raw":[359],"material,":[360],"including":[361],"discards.\r\n\r\nTherefore,":[362],"strongly":[364],"depends":[365],"systems":[372],"ensure":[379],"satisfaction":[381],"patients\u2019":[383],"using":[385],"manufacturing":[391],"agreements":[399],"between":[400],"fractionators":[403],"thus":[404],"reducing":[405],"supplies":[406],"pharmaceutical":[409],"market8\u201310.":[410],"also":[412],"clinical":[415],"plasma11":[418],"plays":[422],"key":[424],"self-sufficiency.\r\n\r\nThe":[427],"aim":[428],"present":[431],"paper":[432],"address":[435],"issue":[437],"Italy":[442],"2011.":[444]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
