{"id":"https://openalex.org/W370166137","doi":null,"title":"The applied use of psychotherapy in the study of the psychobiology of depression.","display_name":"The applied use of psychotherapy in the study of the psychobiology of depression.","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W370166137","mag":"370166137","pmid":"https://pubmed.ncbi.nlm.nih.gov/22700058","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3330272"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3330272","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3330272","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Psychother Pract Res","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3330272","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109331301","display_name":"Michael E. Thase","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M E Thase","raw_affiliation_strings":["Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109086156","display_name":"Anne D. Simons","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A D Simons","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.1058,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.96321794,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"1","issue":"1","first_page":"72","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.5654000043869019,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.5654000043869019,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.30079999566078186,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.06129999831318855,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melancholic-depression","display_name":"endogenous depression","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.9350000023841858},{"id":"https://openalex.org/keywords/sleep-eeg","display_name":"sleep EEG","score":0.7950000166893005},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.6119999885559082},{"id":"https://openalex.org/keywords/hypersomnia","display_name":"hypersomnia","score":0.6740000247955322},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.8939999938011169},{"id":"https://openalex.org/keywords/neurophysiological-markers","display_name":"neurophysiological markers","score":0.5040000081062317},{"id":"https://openalex.org/keywords/remitted-depression","display_name":"remitted depression","score":0.5550000071525574},{"id":"https://openalex.org/keywords/treatment-outcomes","display_name":"treatment outcomes","score":0.33399999141693115}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6558734774589539},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6470354199409485},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.6409592032432556},{"id":"https://openalex.org/C2434490","wikidata":"https://www.wikidata.org/wiki/Q1306920","display_name":"Neurofeedback","level":3,"score":0.4928932189941406},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.46660324931144714},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.44684073328971863},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.38337188959121704},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.34205323457717896},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:3330272","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3330272","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Psychother Pract Res","raw_type":"Text"},{"id":"pmid:22700058","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22700058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of psychotherapy practice and research","raw_type":"Journal Article"},{"id":"mag:370166137","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22700058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3330272","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3330272","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Psychother Pract Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1964071210","https://openalex.org/W1968979483","https://openalex.org/W1969783255","https://openalex.org/W2007836888","https://openalex.org/W2008977521","https://openalex.org/W2049165791","https://openalex.org/W2067495470","https://openalex.org/W2070262996","https://openalex.org/W2086775182","https://openalex.org/W2109226331","https://openalex.org/W2119226169","https://openalex.org/W2141909760","https://openalex.org/W2169217816","https://openalex.org/W2405443059","https://openalex.org/W2416506115"],"related_works":["https://openalex.org/W2032601397","https://openalex.org/W2046459176","https://openalex.org/W2018063701","https://openalex.org/W88265766","https://openalex.org/W2413022431","https://openalex.org/W4231455653","https://openalex.org/W2335918034","https://openalex.org/W2022494361","https://openalex.org/W2004528701","https://openalex.org/W2093725000"],"abstract_inverted_index":{"In":[0],"an":[1],"investigation":[2],"of":[3,51,71,80,85,99,104,127],"electroencephalographic":[4],"(EEG)":[5],"sleep":[6,40,52,83,97,125],"in":[7,26,37,45],"endogenously":[8],"depressed":[9],"outpatients":[10],"before":[11],"and":[12,55,117],"after":[13],"treatment":[14,32,128],"with":[15,91,109],"cognitive":[16],"behavior":[17],"therapy":[18],"(CBT),":[19],"a":[20],"79%":[21],"response":[22,93],"rate":[23],"was":[24,58],"observed":[25],"38":[27],"patients":[28],"completing":[29],"the":[30,69],"16-week":[31],"protocol.":[33],"Despite":[34],"substantial":[35],"improvements":[36],"symptoms,":[38],"EEG":[39,82,124],"did":[41],"not":[42,89],"change":[43],"significantly":[44],"recently":[46],"remitted":[47],"patients.":[48],"Moreover,":[49],"stability":[50,65],"between":[53],"pre-treatment":[54],"post-treatment":[56],"assessment":[57],"confirmed":[59],"by":[60],"highly":[61],"significant":[62],"correlations;":[63],"this":[64],"may":[66,120],"indicate":[67],"either":[68],"presence":[70],"slowly":[72],"healing":[73],"neurophysiological":[74],"\"scars\"":[75],"or":[76],"potential":[77],"trait":[78],"markers":[79],"depression.":[81],"correlates":[84,98,126],"endogenous":[86,105],"depression":[87],"were":[88,107],"correlated":[90,108],"poor":[92],"to":[94],"CBT;":[95],"howeve,":[96],"hypersomnia":[100],"(an":[101],"atypical":[102],"feature":[103],"depression)":[106],"poorer":[110],"outcome.":[111],"These":[112],"findings":[113],"suggest":[114],"that":[115],"CBT":[116],"tricyclic":[118],"antidepressants":[119],"share":[121],"several":[122],"common":[123],"responsivity.":[129]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}