{"id":"https://openalex.org/W37008971","doi":null,"title":"Twenty-four-hour pattern of intraocular pressure in young adults with moderate to severe myopia.","display_name":"Twenty-four-hour pattern of intraocular pressure in young adults with moderate to severe myopia.","publication_year":2002,"publication_date":"2002-07-01","ids":{"openalex":"https://openalex.org/W37008971","mag":"37008971","pmid":"https://pubmed.ncbi.nlm.nih.gov/12091437"},"language":"en","primary_location":{"id":"pmid:12091437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002159057","display_name":"John H.K. Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H K Liu","raw_affiliation_strings":["Department of Ophthalmology, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0946, USA. joliu@ucsd.edu","Glaucoma Center, University of California, San Diego, La Jolla, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0946, USA. joliu@ucsd.edu","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Glaucoma Center, University of California, San Diego, La Jolla, California","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012766008","display_name":"Daniel F. Kripke","orcid":"https://orcid.org/0000-0002-2318-8179","observed_orcids":["https://orcid.org/0000-0002-2318-8179"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel F Kripke","raw_affiliation_strings":["Psychiatry, and the"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, and the","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009749990","display_name":"Michael D. Twa","orcid":"https://orcid.org/0000-0003-4544-5153","observed_orcids":["https://orcid.org/0000-0003-4544-5153"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael D Twa","raw_affiliation_strings":["From the Departments of Ophthalmology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Ophthalmology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006573761","display_name":"Parag A. Gokhale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Parag A Gokhale","raw_affiliation_strings":["Glaucoma Center, University of California, San Diego, La Jolla, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Center, University of California, San Diego, La Jolla, California","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032329264","display_name":"Eric I Jones","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eric I Jones","raw_affiliation_strings":["From the Departments of Ophthalmology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Ophthalmology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091385341","display_name":"Eunha Park","orcid":"https://orcid.org/0000-0002-0960-165X","observed_orcids":["https://orcid.org/0000-0002-0960-165X","https://orcid.org/0009-0005-6062-0441","https://orcid.org/0009-0008-1878-118X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eun-Ha Park","raw_affiliation_strings":["From the Departments of Ophthalmology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Ophthalmology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047923191","display_name":"John E Meehan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John E Meehan","raw_affiliation_strings":["Glaucoma Center, University of California, San Diego, La Jolla, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Center, University of California, San Diego, La Jolla, California","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043994887","display_name":"Robert Neal Weinreb","orcid":"https://orcid.org/0000-0001-9553-3202","observed_orcids":["https://orcid.org/0000-0001-9553-3202","https://orcid.org/0000-0003-4217-4853"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert N Weinreb","raw_affiliation_strings":["Glaucoma Center, University of California, San Diego, La Jolla, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Center, University of California, San Diego, La Jolla, California","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0262,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.92358946,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"43","issue":"7","first_page":"2351","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":0.5806000232696533,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":0.5806000232696533,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.3921000063419342,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraocular-pressure","display_name":"intraocular pressure","score":0.9929999709129333},{"id":"https://openalex.org/keywords/myopia","display_name":"myopia","score":0.8579999804496765},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.9559999704360962},{"id":"https://openalex.org/keywords/axial-length","display_name":"axial length","score":0.9279999732971191},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.8149999976158142},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":1.0},{"id":"https://openalex.org/keywords/posture","display_name":"posture","score":0.5910000205039978},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.7329999804496765},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.3019999861717224}],"concepts":[{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.868865966796875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7551223039627075},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.7098103761672974},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5212781429290771},{"id":"https://openalex.org/C19720800","wikidata":"https://www.wikidata.org/wiki/Q7722","display_name":"Morning","level":2,"score":0.4992494583129883},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.4902499318122864},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.4870586693286896},{"id":"https://openalex.org/C169126688","wikidata":"https://www.wikidata.org/wiki/Q1310580","display_name":"Emmetropia","level":4,"score":0.48222148418426514},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.43277496099472046},{"id":"https://openalex.org/C2776370487","wikidata":"https://www.wikidata.org/wiki/Q1144593","display_name":"Sitting","level":2,"score":0.42298242449760437},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3626559376716614},{"id":"https://openalex.org/C2781135284","wikidata":"https://www.wikidata.org/wiki/Q470427","display_name":"Refractive error","level":3,"score":0.28606486320495605},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.19851750135421753},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1450868546962738},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009216","descriptor_name":"Myopia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:12091437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"mag:37008971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12091437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G5234734580","display_name":"REGULATION OF INTRAOCULAR PRESSURE AND OCULAR BLOOD FLOW","funder_award_id":"R01EY007544","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W53927340","https://openalex.org/W85435396","https://openalex.org/W92280384","https://openalex.org/W113207645","https://openalex.org/W123095488","https://openalex.org/W1482861123","https://openalex.org/W1966382408","https://openalex.org/W1980827660","https://openalex.org/W2003441302","https://openalex.org/W2006130930","https://openalex.org/W2007113499","https://openalex.org/W2008008690","https://openalex.org/W2012297453","https://openalex.org/W2029056867","https://openalex.org/W2029761954","https://openalex.org/W2046086366","https://openalex.org/W2052943416","https://openalex.org/W2053277922","https://openalex.org/W2054348675","https://openalex.org/W2065578608","https://openalex.org/W2078724947","https://openalex.org/W2081549200","https://openalex.org/W2158646468","https://openalex.org/W2415335744","https://openalex.org/W2417026063","https://openalex.org/W2767779965"],"related_works":["https://openalex.org/W2013234774","https://openalex.org/W2034107636","https://openalex.org/W92280384","https://openalex.org/W2021549085","https://openalex.org/W53927340","https://openalex.org/W7138844337","https://openalex.org/W123095488","https://openalex.org/W2087128272","https://openalex.org/W2003780479","https://openalex.org/W7097536372"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"characterize":[2],"the":[3,81,117,131,136,141,147,152,156,168,172,179,184,189,196,203,209,213,216,223,251,263,274,295,298,306,319,323,331],"24-hour":[4,190,232,264,313],"change":[5],"of":[6,66,158,234,266,297,315,336],"intraocular":[7],"pressure":[8,85,269],"(IOP)":[9],"in":[10,50,102,123,126,140,151,167,178,183,208,237,255,262,286,305,318,330,338,351],"young":[11,20,287,339],"adults":[12,288,340],"with":[13,27,38,289,341],"moderate":[14,28,290,342],"to":[15,24,29,61,291,343,349],"severe":[16,30,292,344],"myopia.":[17],"METHODS:":[18],"Nineteen":[19],"adults,":[21],"ages":[22],"18":[23],"25":[25],"years,":[26],"myopia":[31,42,132,169,180,210,345],"(myopia":[32],"group)":[33,44],"and":[34,72,86,98,133,202,222,253,270],"17":[35],"age-matched":[36,307],"volunteers":[37,125],"emmetropia":[39],"or":[40],"mild":[41],"(control":[43],"were":[45,75,89,100,121,194,244],"housed":[46],"for":[47,108],"1":[48],"day":[49,252],"a":[51,92,312],"sleep":[52,57,118,142,173],"laboratory.":[53],"An":[54],"8-hour":[55],"accustomed":[56],"period":[58,143],"was":[59,114,144,164,176,218,259],"assigned":[60],"each":[62],"volunteer.":[63],"Twelve":[64],"measurements":[65,120],"IOP,":[67],"axial":[68],"length,":[69],"blood":[70,84,268],"pressure,":[71],"heart":[73,87,271],"rate":[74,88,272],"taken":[76,122],"at":[77,162,199,219,225,284],"2-hour":[78],"intervals.":[79],"In":[80,116,129,171,212],"wake":[82,153],"period,":[83,119,174],"measured":[90,101],"after":[91,111],"5-minute":[93],"bed":[94],"rest.":[95],"Axial":[96,246],"length":[97,247],"IOP":[99,113,139,150,160,175,192,236,282,317,337],"supine":[103,124,138,191,235,316],"volunteers.":[104],"Volunteers":[105],"then":[106],"sat":[107],"5":[109],"minutes,":[110],"which":[112],"measured.":[115],"bed.":[127],"RESULTS:":[128],"both":[130,238,256],"control":[134,185,214,308,332],"groups,":[135,239],"average":[137,148],"higher":[145],"than":[146,182,303],"sitting":[149],"period.":[154],"However,":[155],"magnitude":[157,296],"this":[159],"elevation":[161],"night":[163,254,285],"significantly":[165,301],"less":[166,177,302],"group.":[170,186,211],"group":[181],"When":[187],"only":[188],"data":[193],"considered,":[195],"trough":[197,217],"occurred":[198,205],"1:30":[200],"AM,":[201],"peak":[204,224],"around":[206],"noon":[207],"group,":[215,321],"9:30":[220],"PM,":[221],"5:30":[226],"AM.":[227],"Least-square":[228],"cosine":[229],"fits":[230],"showed":[231],"rhythms":[233,265],"but":[240,294,322],"their":[241],"phase":[242,324],"timings":[243],"different.":[245],"remained":[248],"unchanged":[249],"throughout":[250],"groups.":[257,276],"There":[258,310],"no":[260],"difference":[261],"mean":[267],"between":[273],"two":[275],"CONCLUSIONS:":[277],"Considering":[278],"habitual":[279],"body":[280],"positions,":[281],"increases":[283],"myopia,":[293],"increase":[299],"is":[300,311,326],"that":[304,329],"subjects.":[309,333],"rhythm":[314],"myopic":[320],"timing":[325],"different":[327],"from":[328],"These":[334],"variations":[335],"are":[346],"not":[347],"related":[348],"changes":[350],"cardiovascular":[352],"parameters.":[353]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}