{"id":"https://openalex.org/W37005379","doi":null,"title":"Geographic Variability in Liver Cancer","display_name":"Geographic Variability in Liver Cancer","publication_year":2006,"publication_date":"2006-11-16","ids":{"openalex":"https://openalex.org/W37005379","mag":"37005379"},"language":"en","primary_location":{"id":"pmh:oai:dnet:tdr_________::c39ce9a853f0477eda6294cd878fcee9","doi":null,"is_oa":false,"landing_page_url":"http://www.tdx.cat/TDX-0528107-151008","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0528107-151008/rcs1de1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064194164","display_name":"Ram\u00f3n Cl\u00e8ries","orcid":"https://orcid.org/0000-0002-3637-4747","observed_orcids":["https://orcid.org/0000-0002-3637-4747"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ram\u00f3n Cl\u00e8ries Soler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064194164"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.07599999755620956,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.053300000727176666,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-liver-cancer","display_name":"primary liver cancer","score":0.9750000238418579},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.902999997138977},{"id":"https://openalex.org/keywords/hepatitis-b-virus","display_name":"hepatitis B virus","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hepatitis-c-virus","display_name":"hepatitis C virus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/regional-variation","display_name":"regional variation","score":0.6079999804496765},{"id":"https://openalex.org/keywords/liver-cancer-mortality","display_name":"liver cancer mortality","score":0.7229999899864197},{"id":"https://openalex.org/keywords/liver-cancer-incidence","display_name":"liver cancer incidence","score":0.859000027179718},{"id":"https://openalex.org/keywords/bayesian-meta-analysis","display_name":"Bayesian meta-analysis","score":0.5350000262260437},{"id":"https://openalex.org/keywords/poisson-mixture-distributions","display_name":"Poisson mixture distributions","score":0.699999988079071},{"id":"https://openalex.org/keywords/comparison-group-selection","display_name":"comparison group selection","score":0.6000000238418579},{"id":"https://openalex.org/keywords/pooled-relative-risk","display_name":"pooled relative risk","score":0.6790000200271606},{"id":"https://openalex.org/keywords/europe","display_name":"Europe","score":0.4000000059604645},{"id":"https://openalex.org/keywords/china","display_name":"China","score":0.40799999237060547},{"id":"https://openalex.org/keywords/taiwan","display_name":"Taiwan","score":0.8769999742507935},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4099999964237213},{"id":"https://openalex.org/keywords/incidence-trends","display_name":"incidence trends","score":0.48100000619888306},{"id":"https://openalex.org/keywords/cancer-registry","display_name":"cancer registry","score":0.35499998927116394}],"concepts":[{"id":"https://openalex.org/C2776231280","wikidata":"https://www.wikidata.org/wiki/Q623031","display_name":"Liver cancer","level":3,"score":0.527930498123169},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.44526875019073486},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4190611243247986},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38383933901786804},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3440772593021393},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20932427048683167},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.18695750832557678}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:dnet:tdr_________::c39ce9a853f0477eda6294cd878fcee9","doi":null,"is_oa":false,"landing_page_url":"http://www.tdx.cat/TDX-0528107-151008","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:www.tdx.cat:10803/4627","doi":null,"is_oa":false,"landing_page_url":"http://www.tdx.cat/TDX-0528107-151008","pdf_url":null,"source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:ddd.uab.cat:37498","doi":null,"is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/37498","pdf_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0528107-151008/rcs1de1.pdf","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Tesi doctoral"},{"id":"pmh:oai:dnet:uabarcelona_::93bb7e8c05f111bbc4cbf15f379259bf","doi":null,"is_oa":false,"landing_page_url":"http://ddd.uab.cat/record/37498","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:37005379","doi":null,"is_oa":false,"landing_page_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0528107-151008/rcs1de1.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306531624","display_name":"TDX (Tesis Doctorals en Xarxa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ddd.uab.cat:37498","doi":null,"is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/37498","pdf_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0528107-151008/rcs1de1.pdf","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Tesi doctoral"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W37005379.pdf","grobid_xml":"https://content.openalex.org/works/W37005379.grobid-xml"},"referenced_works_count":213,"referenced_works":["https://openalex.org/W17163568","https://openalex.org/W135145434","https://openalex.org/W142029416","https://openalex.org/W187423019","https://openalex.org/W204797971","https://openalex.org/W437178797","https://openalex.org/W624674342","https://openalex.org/W1492157159","https://openalex.org/W1494805044","https://openalex.org/W1511848366","https://openalex.org/W1513684110","https://openalex.org/W1525535257","https://openalex.org/W1528905581","https://openalex.org/W1552290465","https://openalex.org/W1562701145","https://openalex.org/W1567548236","https://openalex.org/W1578706143","https://openalex.org/W1588313728","https://openalex.org/W1589782664","https://openalex.org/W1593202790","https://openalex.org/W1594784326","https://openalex.org/W1602320701","https://openalex.org/W1829582223","https://openalex.org/W1926896651","https://openalex.org/W1963915199","https://openalex.org/W1965347165","https://openalex.org/W1966448677","https://openalex.org/W1966513832","https://openalex.org/W1968303973","https://openalex.org/W1971529620","https://openalex.org/W1972009756","https://openalex.org/W1973514550","https://openalex.org/W1975090893","https://openalex.org/W1975166857","https://openalex.org/W1976462318","https://openalex.org/W1980528615","https://openalex.org/W1983797549","https://openalex.org/W1985905165","https://openalex.org/W1988051941","https://openalex.org/W1988774293","https://openalex.org/W1988872877","https://openalex.org/W1990939301","https://openalex.org/W1991646200","https://openalex.org/W1995909411","https://openalex.org/W2000857598","https://openalex.org/W2000931643","https://openalex.org/W2004014822","https://openalex.org/W2004311892","https://openalex.org/W2005674014","https://openalex.org/W2007502550","https://openalex.org/W2011650756","https://openalex.org/W2013099477","https://openalex.org/W2014581807","https://openalex.org/W2015558203","https://openalex.org/W2016527730","https://openalex.org/W2017087833","https://openalex.org/W2018635977","https://openalex.org/W2026996728","https://openalex.org/W2027001482","https://openalex.org/W2027613324","https://openalex.org/W2028693568","https://openalex.org/W2030205674","https://openalex.org/W2030597423","https://openalex.org/W2031028425","https://openalex.org/W2031453508","https://openalex.org/W2032123392","https://openalex.org/W2033703798","https://openalex.org/W2033704186","https://openalex.org/W2033850460","https://openalex.org/W2036675501","https://openalex.org/W2038543277","https://openalex.org/W2038885294","https://openalex.org/W2039621565","https://openalex.org/W2040722791","https://openalex.org/W2045057355","https://openalex.org/W2045656233","https://openalex.org/W2045934614","https://openalex.org/W2046526854","https://openalex.org/W2047810781","https://openalex.org/W2050652595","https://openalex.org/W2053891585","https://openalex.org/W2054469530","https://openalex.org/W2055678947","https://openalex.org/W2056827569","https://openalex.org/W2059011261","https://openalex.org/W2061918140","https://openalex.org/W2062395204","https://openalex.org/W2063390008","https://openalex.org/W2064428351","https://openalex.org/W2067309872","https://openalex.org/W2067517550","https://openalex.org/W2069309194","https://openalex.org/W2071119229","https://openalex.org/W2071291950","https://openalex.org/W2071655843","https://openalex.org/W2072169887","https://openalex.org/W2073942238","https://openalex.org/W2076683498","https://openalex.org/W2078145079","https://openalex.org/W2078797029","https://openalex.org/W2080825536","https://openalex.org/W2081539827","https://openalex.org/W2081826807","https://openalex.org/W2084180808","https://openalex.org/W2084774262","https://openalex.org/W2087564721","https://openalex.org/W2089043214","https://openalex.org/W2089313156","https://openalex.org/W2089482945","https://openalex.org/W2089571778","https://openalex.org/W2092209698","https://openalex.org/W2095138392","https://openalex.org/W2095427717","https://openalex.org/W2096808350","https://openalex.org/W2097820722","https://openalex.org/W2097962518","https://openalex.org/W2098008728","https://openalex.org/W2099449435","https://openalex.org/W2099865291","https://openalex.org/W2101197201","https://openalex.org/W2103406187","https://openalex.org/W2103637700","https://openalex.org/W2103638317","https://openalex.org/W2103827797","https://openalex.org/W2104144324","https://openalex.org/W2104232463","https://openalex.org/W2106791445","https://openalex.org/W2107001696","https://openalex.org/W2110221643","https://openalex.org/W2112510101","https://openalex.org/W2113988779","https://openalex.org/W2114220616","https://openalex.org/W2115302256","https://openalex.org/W2115754856","https://openalex.org/W2117845723","https://openalex.org/W2118713001","https://openalex.org/W2120970673","https://openalex.org/W2122576167","https://openalex.org/W2123323832","https://openalex.org/W2124073571","https://openalex.org/W2124658642","https://openalex.org/W2125684356","https://openalex.org/W2127550752","https://openalex.org/W2130416410","https://openalex.org/W2131628232","https://openalex.org/W2132254613","https://openalex.org/W2138651751","https://openalex.org/W2138687943","https://openalex.org/W2138786372","https://openalex.org/W2139960280","https://openalex.org/W2140481064","https://openalex.org/W2146060607","https://openalex.org/W2151650153","https://openalex.org/W2152664737","https://openalex.org/W2153124733","https://openalex.org/W2154076862","https://openalex.org/W2155036950","https://openalex.org/W2156275008","https://openalex.org/W2156922255","https://openalex.org/W2158635250","https://openalex.org/W2158914520","https://openalex.org/W2159171613","https://openalex.org/W2159486148","https://openalex.org/W2160036457","https://openalex.org/W2160537948","https://openalex.org/W2161132263","https://openalex.org/W2164692188","https://openalex.org/W2165598087","https://openalex.org/W2168374843","https://openalex.org/W2169986048","https://openalex.org/W2170712385","https://openalex.org/W2176128304","https://openalex.org/W2237132745","https://openalex.org/W2245424097","https://openalex.org/W2284164035","https://openalex.org/W2314866596","https://openalex.org/W2321119966","https://openalex.org/W2322310797","https://openalex.org/W2394853681","https://openalex.org/W2397911245","https://openalex.org/W2408391934","https://openalex.org/W2410301016","https://openalex.org/W2410696340","https://openalex.org/W2411539299","https://openalex.org/W2412535562","https://openalex.org/W2412827975","https://openalex.org/W2413622929","https://openalex.org/W2414867831","https://openalex.org/W2417214543","https://openalex.org/W2418462454","https://openalex.org/W2462018652","https://openalex.org/W2463930553","https://openalex.org/W2483849182","https://openalex.org/W2488201047","https://openalex.org/W2490476487","https://openalex.org/W2494440310","https://openalex.org/W2770388669","https://openalex.org/W2795716722","https://openalex.org/W2884606331","https://openalex.org/W3007026351","https://openalex.org/W3046893829","https://openalex.org/W3085323863","https://openalex.org/W3126246200","https://openalex.org/W3145314263","https://openalex.org/W3159004246","https://openalex.org/W3164653583","https://openalex.org/W3214654895","https://openalex.org/W4210847921","https://openalex.org/W4211260477","https://openalex.org/W4231378768","https://openalex.org/W4297981912","https://openalex.org/W4301392566","https://openalex.org/W4310945180"],"related_works":["https://openalex.org/W7056107333","https://openalex.org/W2004261972","https://openalex.org/W2315566442","https://openalex.org/W4386726735","https://openalex.org/W2188418835","https://openalex.org/W187423019","https://openalex.org/W2739552257","https://openalex.org/W95163395","https://openalex.org/W4406068995","https://openalex.org/W6906548169"],"abstract_inverted_index":{"At":[0],"the":[1,4,12,21,58,106,120,147,150,184,201,207,210,226,249,254,324,355,363,376,405,444,458,482,488,501,536,555,599,648,683,707,739,759,905,912,929,960,988,1000,1030,1038,1052],"beginning":[2],"of":[3,30,69,97,111,149,171,174,176,194,203,209,232,238,251,253,256,268,279,316,365,396,407,446,460,463,484,504,544,569,582,602,637,662,685,756,770,780,840,908,999,1032,1040,1051],"21st":[5],"century,":[6],"primary":[7,397],"liver":[8,177,398,702,726,751,765,991],"cancer":[9,178,399,664,914],"(PLC)":[10],"remains":[11],"fifth":[13],"most":[14],"common":[15],"malignancy":[16],"in":[17,23,78,85,129,159,186,190,299,320,359,387,400,402,412,472,524,554,605,612,621,643,666,687,701,704,715,725,728,776,783,789,798,807,816,837,848,852,860,871,881,899,922,925,933,941,990,1010,1029],"men":[18],"worldwide,":[19],"and":[20,27,53,81,109,126,137,157,206,306,323,409,419,436,448,465,467,491,500,518,562,576,584,640,656,689,712,718,778,887,977,982,1017,1054,1059],"eighth":[22],"women.":[24],"Central":[25],"Africa":[26],"South":[28],"East":[29],"Asia":[31],"are":[32,57],"high":[33,300,360,600,618,654],"risk":[34,60,175,266,301,328,361,581,601,971],"geographic":[35,107,131,204],"areas":[36,302,329],"for":[37,62,65,270,303,330,440,443,476,487,512,559,749,763,1043,1064],"PLC,":[38,63,331],"whereas":[39,531,758],"developed":[40,86,873],"countries":[41,87,415,527,534,592,646,669],"appear":[42,825],"to":[43,91,102,122,161,247,261,284,311,431,455,468,550,609,680,737,826,829,868,879,904,968,1005,1023,1049],"be":[44,551,610,625,634,827,877,966],"generally":[45],"low":[46,327,649,768,906],"risk.":[47],"Infections":[48],"with":[49,163,566,593,627,692,753,767,1007],"hepatitis":[50],"B":[51],"(HBV)":[52],"C":[54],"(HCV)":[55],"viruses":[56],"main":[59],"factors":[61,972],"accounting":[64,442,475],"well":[66,673,721,748],"over":[67],"80%":[68],"PLC":[70,84,98,124,187,271,282,304,417,441,473,520,603,638,650,686],"cases":[71,909],"detected":[72,76,604],"worldwide.":[73],"The":[74,95,166,229,241,276,390,495,515,542,617,660,695,997],"recently":[75],"increase":[77,775,989],"both":[79,456,560,926],"incidence":[80,125,418,519,583,639,711,777],"mortality":[82,127,188,517,585,641,713,723,779,850,924,993],"by":[83,281,614,911],"is":[88,375,670,1047],"strongly":[89],"related":[90,283,828,1048],"these":[92,112,1060],"viral":[93],"infections.":[94],"evaluation":[96],"time":[99,378,740],"trends":[100,700,714,724],"needs":[101],"take":[103],"into":[104,199],"consideration":[105,200],"distribution":[108,395,684],"effect":[110,406,445,459,543,958],"viruses.":[113],"This":[114,374,451,956],"thesis":[115],"presents":[116],"three":[117,1011],"studies":[118,173,193,317,332,352,677,839],"which":[119,333,353,557,1046],"aim":[121],"describe":[123],"issues":[128,1028],"different":[130,143,461,1015],"areas,":[132,362],"each":[133,141,1024],"addressing":[134,1018],"several":[135],"epidemiological":[136],"methodological":[138,1020],"issues.":[139],"For":[140],"study,":[142,168,392,697],"statistical":[144,230,1012,1027],"methods":[145,231],"on":[146,236,416,425],"basis":[148],"Bayesian":[151,426,479,1001,1033],"inference":[152,427,480],"have":[153,428,507,734,917],"been":[154,245,385,429,508,735],"proposed,":[155],"evaluated":[156],"discussed":[158],"order":[160],"cope":[162,1006],"extra-Poisson":[164,1008],"variability.":[165],"first":[167,377],"entitled":[169,393,698],"\"Meta-analysis":[170],"cohort":[172,192,957],"death":[179,269,280],"among":[180,272,994],"HBV":[181,196,274,285,408,447,464,545,561,655,980],"carriers\",":[182],"evaluates":[183,404],"variability":[185,471,1009],"reported":[189,910],"11":[191],"male":[195,273],"carriers,":[197],"taking":[198],"effects":[202],"area":[205,623],"choice":[208],"general":[211,356],"population":[212],"versus":[213],"a":[214,263,380,567,579,895,919],"more":[215],"comparable":[216],"group":[217],"such":[218],"as":[219,225,339,510,672,674,720,722,835],"HBV-negative":[220],"workers":[221,335],"or":[222,336,979],"blood":[223,337],"donors":[224,338],"comparison":[227,340],"group.":[228],"this":[233,622,954],"study":[234,930],"focuses":[235],"mixtures":[237],"Poisson":[239,257,422],"distributions.":[240],"\"stickbreaking\"":[242],"method":[243],"has":[244,384],"used":[246,334,354,430,509,736],"estimate":[248],"number":[250,503,755,769,907],"components":[252],"mixture":[255],"distributions,":[258],"and,":[259],"thus":[260],"obtain":[262],"pooled":[264,277],"relative":[265],"(RR)":[267],"carriers.":[275],"RR":[278],"infection":[286,477,546],"was":[287,367,547],"23.5":[288],"(95%":[289,346,369],"Credibility":[290],"Interval":[291],"(CRI):":[292],"14.9":[293],"-":[294,349,372,589],"44.5).":[295],"Studies":[296],"carried":[297,318],"out":[298,319],"(China":[305],"Taiwan)":[307],"showed":[308,535],"RRs":[309,343,366,521,538,651],"2":[310],"5-fold":[312],"higher":[313,345,571,580],"than":[314,351,572,591],"those":[315,750,764],"Europe,":[321,679],"Japan":[322],"U.S..":[325],"In":[326],"groups":[341],"had":[342,578],"1.9-fold":[344],"CRI:":[347,370,794,803,812,821,856,864,937,945],"1.2":[348],"3.1)":[350],"population.":[357],"However,":[358,890],"ratio":[364],"5.3-fold":[368],"3.4":[371],"7.9).":[373],"that":[379,693,744,824,869,875,962],"\"healthy":[381],"donor":[382],"effect\"":[383],"quantified":[386],"longitudinal":[388],"studies.":[389],"second":[391],"\"Geographic":[394],"Europe":[401,607,688],"2002\"":[403],"HCV":[410,449,563,570,594,615,619,657,675,830,978],"seroprevalence":[411,620],"38":[413],"European":[414,526,533,645,668],"mortality.":[420],"Mixed":[421],"models":[423,733,746,761],"based":[424],"smooth":[432],"Standardized":[433],"Incidence":[434],"(SIR)":[435],"Mortality":[437],"(SMR)":[438],"ratios":[439],"prevalences.":[450],"approach":[452,1002],"enabled":[453],"us":[454,1004],"examine":[457],"levels":[462],"HCV,":[466],"identify":[469],"remaining":[470],"after":[474],"rates.":[478],"allowed":[481,1003],"determination":[483],"posterior":[485],"probabilities":[486],"somoothed":[489],"SIRs":[490],"SMRs":[492],"(hereafter":[493],"RRs).":[494],"Deviance":[496],"Information":[497],"Criterion":[498],"(DIC)":[499],"\"effective":[502],"parameters\"":[505],"(pD)":[506],"tools":[511],"model":[513,556,1044,1056],"choice.":[514],"highest":[516],"were":[522],"found":[523,549,743,773,844,870],"Southern":[525,606],"(RR":[528,539,586],"range":[529],"0.9-2.4),":[530],"Northern":[532],"lowest":[537],"range:":[540,587],"0.3-0.9).":[541],"not":[548,893,952],"statistically":[552],"significant":[553,896],"accounted":[558],"prevalence.":[564],"Countries":[565],"prevalence":[568,595,676],"2%":[573],"(e.g.:":[574],"Italy":[575],"Spain)":[577],"1.28":[588],"1.78)":[590],"below":[596],"1%.":[597],"Thus,":[598],"appears":[608],"explained,":[611],"part,":[613],"infection.":[616],"could":[624,876,965,986],"associated":[626],"exposure":[628,831],"30-50":[629],"years":[630,833],"ago.":[631],"There":[632],"may":[633],"an":[635,774,845],"underestimation":[636],"rates":[642],"Eastern":[644,667],"given":[647],"reported,":[652],"despite":[653],"seroprevalences":[658],"observed.":[659],"implementation":[661],"population-based":[663],"registries":[665],"warranted,":[671],"across":[678],"better":[681,885],"determine":[682],"its":[690],"relationship":[691],"virus.":[694],"last":[696],"\"Time":[699],"disease":[703],"Spain":[705,784],"during":[706,928],"period":[708,931],"198397\",":[709],"describes":[710],"hepatocellular":[716,781],"carcinoma":[717,782],"cholangiocarcinoma":[719,849,900],"cirrhosis":[727,923,992],"Spain.":[729],"Autoregressive":[730],"age-period-cohort":[731],"(APC)":[732],"evaluate":[738],"trends.":[741],"We":[742,772,842,916],"APC":[745],"performed":[747],"diseases":[752,766],"large":[754],"cases,":[757],"age-period":[760],"did":[762,892,951],"cases.":[771],"(annual":[785],"percent":[786],"change":[787],"(APCH)":[788],"men's":[790,808],"incidence:":[791,800],"6.6%,":[792],"95%":[793,802,811,820,855,863,936,944],"5.8,":[795],"8.1:":[796],"APCH":[797,806,815,859,940],"women's":[799,817],"4.5%,":[801],"1.4%,":[804],"7.3%;":[805],"mortality:":[809,818],"6.8%,":[810],"5.8%,":[813],"8.1%;":[814],"5.1%,":[819],"3.5%,":[822],"6.3%),":[823],"30":[832],"ago,":[834],"described":[836],"other":[838],"PLC.":[841],"also":[843],"increasing":[846,897],"trend":[847,898,921],"(APCH":[851,932],"men:":[853,934],"17.1%,":[854],"13.5%,":[857],"21.2%;":[858],"women:":[861,942],"15.0%,":[862],"11.5%,":[865],"19.5%)":[866],"similar":[867],"some":[872,969],"countries,":[874],"attributed":[878],"improvement":[880],"diagnosis":[882],"resulting":[883],"from":[884],"imaging":[886],"diagnostic":[888],"techniques.":[889],"we":[891],"detect":[894],"incidence,":[901],"perhaps":[902],"due":[903],"Spanish":[913],"registries.":[915],"observed":[918],"decreasing":[920],"sexes":[927],"-3.1%,":[935],"-5.1,":[938],"-1.9%;":[939],"-2.9%;":[943],"-6.2%,":[946],"-1.3%),":[947],"although":[948],"younger":[949,963,995],"cohorts":[950,964],"show":[953],"pattern.":[955],"suggests":[959],"possibility":[961],"exposed":[967],"additional":[970],"besides":[973],"alcohol":[974],"consumption.":[975],"HIV":[976],"co-infection":[981],"intravenous":[983],"drug":[984],"addiction":[985],"explain":[987],"cohorts.":[996],"flexibility":[998],"analyses,":[1013],"applying":[1014],"models,":[1016],"relevant":[1019],"aspects":[1021],"specific":[1022],"problem.":[1025],"Challenging":[1026],"framework":[1031],"applied":[1034],"modelling":[1035],"are:":[1036],"i)":[1037],"selection":[1039,1057],"prior":[1041],"distributions":[1042],"parameters,":[1045],"convergence":[1050],"model;":[1053],"ii)":[1055],"procedures,":[1058],"remain":[1061],"important":[1062],"considerations":[1063],"future":[1065],"research.":[1066]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
