{"id":"https://openalex.org/W36969803","doi":"https://doi.org/10.1007/978-1-4612-2536-2_10","title":"T-Lymphocyte Response in Renal Cell Carcinoma","display_name":"T-Lymphocyte Response in Renal Cell Carcinoma","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W36969803","doi":"https://doi.org/10.1007/978-1-4612-2536-2_10","mag":"36969803"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4612-2536-2_10","doi":"https://doi.org/10.1007/978-1-4612-2536-2_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-2536-2_10","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Renal Cell Carcinoma","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W611653633","display_name":"Biology of Renal Cell Carcinoma"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111616386","display_name":"Kyogo Itoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyogo Itoh","raw_affiliation_strings":["Department of Immunology, Kurume University School of Medicine, Kurume, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Kurume University School of Medicine, Kurume, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014673660","display_name":"Lazel B. Augustus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lazel B. Augustus","raw_affiliation_strings":["Department of Immunology, University of Texas, M.D. Anderson Cancer Center, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, University of Texas, M.D. Anderson Cancer Center, Houston, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110124663","display_name":"Masanobu Nakao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanobu Nakao","raw_affiliation_strings":["Department of Immunology, Kurume University School of Medicine, Kurume, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Kurume University School of Medicine, Kurume, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019422854","display_name":"Jiro Miyajima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jiro Miyajima","raw_affiliation_strings":["Department of Immunology, Kurume University School of Medicine, Kurume, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Kurume University School of Medicine, Kurume, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087385450","display_name":"Omar E. Eton","orcid":"https://orcid.org/0000-0002-9141-553X","observed_orcids":["https://orcid.org/0000-0002-9141-553X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omar Eton","raw_affiliation_strings":["Department of Medical Oncology, University of Texas, M.D.Anderson Cancer Center, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, University of Texas, M.D.Anderson Cancer Center, Houston, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079730294","display_name":"David A. Swamson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Swamson","raw_affiliation_strings":["Department of Urology, University of Texas, M.D. Anderson Cancer Center, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, University of Texas, M.D. Anderson Cancer Center, Houston, USA","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"94","last_page":"105"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.7875999808311462,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.7875999808311462,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.1143999993801117,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.07760000228881836,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-cell-carcinoma","display_name":"renal cell carcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-infiltrating-lymphocytes","display_name":"tumor-infiltrating lymphocytes","score":0.9919999837875366},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.6399999856948853},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7260000109672546},{"id":"https://openalex.org/keywords/tumor-specific-cytotoxic-t-lymphocytes","display_name":"tumor-specific cytotoxic T lymphocytes","score":0.75},{"id":"https://openalex.org/keywords/tumor-immunogenicity","display_name":"tumor immunogenicity","score":0.800000011920929},{"id":"https://openalex.org/keywords/oligoclonal-expansion","display_name":"oligoclonal expansion","score":0.8140000104904175},{"id":"https://openalex.org/keywords/memory-t-cells","display_name":"memory T cells","score":0.7850000262260437},{"id":"https://openalex.org/keywords/tumor-cell-lysis","display_name":"tumor cell lysis","score":0.5889999866485596},{"id":"https://openalex.org/keywords/tumor-specific-t-cells","display_name":"tumor-specific T cells","score":0.375}],"concepts":[{"id":"https://openalex.org/C2778326572","wikidata":"https://www.wikidata.org/wiki/Q7852668","display_name":"Tumor-infiltrating lymphocytes","level":4,"score":0.6154149770736694},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5246080160140991},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.511499285697937},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4947628378868103},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.47067174315452576},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.44905945658683777},{"id":"https://openalex.org/C2781462264","wikidata":"https://www.wikidata.org/wiki/Q78482053","display_name":"CD16","level":5,"score":0.44753432273864746},{"id":"https://openalex.org/C28651165","wikidata":"https://www.wikidata.org/wiki/Q4259786","display_name":"Lymphokine-activated killer cell","level":5,"score":0.4405856132507324},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.42892706394195557},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4253646433353424},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.39306509494781494},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.3865675926208496},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.31718724966049194},{"id":"https://openalex.org/C129374314","wikidata":"https://www.wikidata.org/wiki/Q909381","display_name":"Interleukin 21","level":4,"score":0.2705513536930084},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08991652727127075},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4612-2536-2_10","doi":"https://doi.org/10.1007/978-1-4612-2536-2_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-2536-2_10","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Renal Cell Carcinoma","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W789413736","https://openalex.org/W1494923199","https://openalex.org/W1503200847","https://openalex.org/W1599327500","https://openalex.org/W1771969015","https://openalex.org/W1887940719","https://openalex.org/W1891775215","https://openalex.org/W1964056924","https://openalex.org/W1973291904","https://openalex.org/W1976548176","https://openalex.org/W1986544190","https://openalex.org/W1989775015","https://openalex.org/W1990668606","https://openalex.org/W1996700697","https://openalex.org/W2002076761","https://openalex.org/W2008581311","https://openalex.org/W2087262264","https://openalex.org/W2092401374","https://openalex.org/W2099616968","https://openalex.org/W2103069179","https://openalex.org/W2120137683","https://openalex.org/W2135760279","https://openalex.org/W2136353300","https://openalex.org/W2159673453","https://openalex.org/W2170942306","https://openalex.org/W2172009488","https://openalex.org/W2322553446","https://openalex.org/W2406105097","https://openalex.org/W2470143927"],"related_works":["https://openalex.org/W2406105097","https://openalex.org/W2158488906","https://openalex.org/W1990601937","https://openalex.org/W2323345521","https://openalex.org/W1981560649","https://openalex.org/W2042411394","https://openalex.org/W2087262264","https://openalex.org/W1538690841","https://openalex.org/W2002072541","https://openalex.org/W2782496117"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}