{"id":"https://openalex.org/W36594241","doi":null,"title":"[Primary progressive aphasia (Mesulam syndrome)].","display_name":"[Primary progressive aphasia (Mesulam syndrome)].","publication_year":1993,"publication_date":"1993-05-01","ids":{"openalex":"https://openalex.org/W36594241","mag":"36594241","pmid":"https://pubmed.ncbi.nlm.nih.gov/8316530"},"language":"fr","primary_location":{"id":"pmid:8316530","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8316530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Presse medicale (Paris, France : 1983)","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109223025","display_name":"Michel Habib","orcid":"https://orcid.org/0000-0001-5955-9608","observed_orcids":["https://orcid.org/0000-0001-5955-9608"]},"institutions":[{"id":"https://openalex.org/I4210162909","display_name":"H\u00f4pital de la Timone","ror":"https://ror.org/05jrr4320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210162909"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M Habib","raw_affiliation_strings":["Service de Neurologie, CHU Timone, Marseille"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Neurologie, CHU Timone, Marseille","institution_ids":["https://openalex.org/I4210162909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054006135","display_name":"Jean Pelletier","orcid":"https://orcid.org/0000-0001-9730-7567","observed_orcids":["https://orcid.org/0000-0001-9730-7567"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Pelletier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"R Khalil","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Khalil","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.00403413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"22","issue":"16","first_page":"757","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10465","display_name":"Neurobiology of Language and Bilingualism","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-progressive-aphasia","display_name":"primary progressive aphasia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.6449999809265137},{"id":"https://openalex.org/keywords/pick-s-disease","display_name":"Pick's disease","score":0.9879999756813049},{"id":"https://openalex.org/keywords/degenerative-dementia","display_name":"degenerative dementia","score":0.625},{"id":"https://openalex.org/keywords/left-hemisphere-asymmetry","display_name":"left hemisphere asymmetry","score":0.8420000076293945},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"neuroimaging","score":0.6489999890327454},{"id":"https://openalex.org/keywords/neuropathology","display_name":"neuropathology","score":0.8859999775886536},{"id":"https://openalex.org/keywords/autopsy-findings","display_name":"autopsy findings","score":0.5239999890327454},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C2779140760","wikidata":"https://www.wikidata.org/wiki/Q18767","display_name":"Primary progressive aphasia","level":5,"score":0.9258986115455627},{"id":"https://openalex.org/C2779422653","wikidata":"https://www.wikidata.org/wiki/Q2836","display_name":"Aphasia","level":2,"score":0.7968826293945312},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6921737790107727},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6634383201599121},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6321331262588501},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5669888257980347},{"id":"https://openalex.org/C2780130745","wikidata":"https://www.wikidata.org/wiki/Q1650750","display_name":"Neuropathology","level":3,"score":0.533739447593689},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.467011034488678},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4445450007915497},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.4427289664745331},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36717212200164795},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.22964265942573547},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.227701336145401},{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.10576486587524414}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001037","descriptor_name":"Aphasia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001037","descriptor_name":"Aphasia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013577","descriptor_name":"Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8316530","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8316530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Presse medicale (Paris, France : 1983)","raw_type":"English Abstract"},{"id":"mag:36594241","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8316530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":104,"referenced_works":["https://openalex.org/W9849964","https://openalex.org/W19113225","https://openalex.org/W53996391","https://openalex.org/W184082306","https://openalex.org/W205940051","https://openalex.org/W646651436","https://openalex.org/W1109639756","https://openalex.org/W1572920194","https://openalex.org/W1580339584","https://openalex.org/W1589007430","https://openalex.org/W1786299986","https://openalex.org/W1929717471","https://openalex.org/W1966681600","https://openalex.org/W1967672819","https://openalex.org/W1972056133","https://openalex.org/W1974476087","https://openalex.org/W1983944654","https://openalex.org/W1984440342","https://openalex.org/W1990644905","https://openalex.org/W1990752141","https://openalex.org/W1991346678","https://openalex.org/W1994014733","https://openalex.org/W1997376718","https://openalex.org/W1998145120","https://openalex.org/W2003806642","https://openalex.org/W2005409914","https://openalex.org/W2005613270","https://openalex.org/W2007522021","https://openalex.org/W2007615180","https://openalex.org/W2008857692","https://openalex.org/W2019683289","https://openalex.org/W2026693637","https://openalex.org/W2026919841","https://openalex.org/W2031683173","https://openalex.org/W2039765075","https://openalex.org/W2040269004","https://openalex.org/W2040387110","https://openalex.org/W2046178109","https://openalex.org/W2050801925","https://openalex.org/W2050851896","https://openalex.org/W2052553321","https://openalex.org/W2052947772","https://openalex.org/W2069085537","https://openalex.org/W2075086348","https://openalex.org/W2087531263","https://openalex.org/W2088255586","https://openalex.org/W2090310262","https://openalex.org/W2092348127","https://openalex.org/W2096559770","https://openalex.org/W2108645706","https://openalex.org/W2114234975","https://openalex.org/W2119437574","https://openalex.org/W2135664375","https://openalex.org/W2151054995","https://openalex.org/W2154711032","https://openalex.org/W2161529563","https://openalex.org/W2187531586","https://openalex.org/W2206819156","https://openalex.org/W2235653829","https://openalex.org/W2308456886","https://openalex.org/W2323926031","https://openalex.org/W2328280316","https://openalex.org/W2335382466","https://openalex.org/W2513367245","https://openalex.org/W2595581463","https://openalex.org/W2595926111","https://openalex.org/W2597372442","https://openalex.org/W2742200852","https://openalex.org/W2781883940","https://openalex.org/W2793902970","https://openalex.org/W2794304570","https://openalex.org/W2800640877","https://openalex.org/W2804451005","https://openalex.org/W2870351107","https://openalex.org/W2889237718","https://openalex.org/W2889389523","https://openalex.org/W2894399138","https://openalex.org/W2898591920","https://openalex.org/W2906251771","https://openalex.org/W2938376176","https://openalex.org/W2940851105","https://openalex.org/W2954441523","https://openalex.org/W2964024721","https://openalex.org/W3004575133","https://openalex.org/W3006825624","https://openalex.org/W3015880009","https://openalex.org/W3023363600","https://openalex.org/W3034315200","https://openalex.org/W3107549158","https://openalex.org/W3112249315","https://openalex.org/W3123194937","https://openalex.org/W3152981814","https://openalex.org/W3162277331","https://openalex.org/W3170909446","https://openalex.org/W3183063913","https://openalex.org/W3186478925","https://openalex.org/W3196917655","https://openalex.org/W3197982694","https://openalex.org/W3213466144","https://openalex.org/W3215951774","https://openalex.org/W4206174278","https://openalex.org/W4211099883","https://openalex.org/W4220935141","https://openalex.org/W4379032832"],"related_works":["https://openalex.org/W2344339111","https://openalex.org/W2123195968","https://openalex.org/W2342007231","https://openalex.org/W1985260397","https://openalex.org/W4243835081","https://openalex.org/W2150070900","https://openalex.org/W1959308195","https://openalex.org/W2094288610","https://openalex.org/W2030212643","https://openalex.org/W1693625036"],"abstract_inverted_index":{"Primary":[0],"progressive":[1,79,175],"aphasia":[2,80],"is":[3,25,66,81],"defined":[4],"as":[5,30],"a":[6,31,62,89,121,135,189,193],"gradually":[7,10],"appeared":[8],"and":[9,111,146,167],"worsening":[11],"disorder":[12],"of":[13,19,41,77,101,117,123,139,143,155,196],"speech":[14],"without":[15],"any":[16],"major":[17],"alteration":[18],"the":[20,42,69,85,99,115,118,124,130,140,153,178],"other":[21],"cognitive":[22],"functions.":[23],"It":[24],"regarded":[26],"by":[27,109],"some":[28],"authors":[29],"syndrome":[32],"which":[33],"may":[34],"be":[35,159],"due":[36],"to":[37,49,61,114,134,148],"various":[38],"degenerative":[39,71,197],"diseases":[40],"cerebral":[43,168],"cortex":[44],"(notably":[45],"Alzheimer's":[46,144,156],"disease,":[47],"owing":[48],"its":[50],"frequency),":[51],"while":[52],"others":[53],"see":[54],"in":[55,107,161],"it":[56,83],"an":[57],"autonomous":[58],"disease":[59,145,157],"related":[60],"neuropathological":[63,136],"process":[64],"that":[65,82,129,180],"distinct":[67],"from":[68],"main":[70],"dementias.":[72,198],"The":[73],"principal":[74],"clinical":[75,165],"particularity":[76],"primary":[78,174],"spares":[84],"patient's":[86],"autonomy":[87],"for":[88],"long":[90],"time,":[91],"but":[92],"ultimately":[93],"turns":[94],"into":[95],"global":[96],"dementia.":[97],"Despite":[98],"diversity":[100],"aphasic":[102],"aspects":[103],"accompanied":[104],"or":[105],"not,":[106],"neuroimaging,":[108],"morphological":[110],"metabolic":[112],"asymmetry":[113],"expense":[116],"left":[119],"hemisphere,":[120],"review":[122],"autopsy":[125],"cases":[126],"published":[127],"shows":[128],"vast":[131],"majority":[132],"corresponded":[133],"pattern":[137],"devoid":[138],"characteristic":[141],"features":[142],"nearer":[147],"Pick's":[149],"disease.":[150],"In":[151],"practice,":[152],"diagnosis":[154],"can":[158],"excluded":[160],"all":[162],"patients":[163],"whose":[164],"presentation":[166],"neuroimaging":[169],"results":[170],"are":[171],"compatible":[172],"with":[173],"aphasia.":[176],"Moreover,":[177],"fact":[179],"this":[181],"new":[182],"clinicoanatomical":[183],"entity":[184],"has":[185],"been":[186],"individualized":[187],"constitutes":[188],"definite":[190],"step":[191],"towards":[192],"better":[194],"comprehension":[195]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}