{"id":"https://openalex.org/W36571649","doi":null,"title":"[Application of cardiopulmonary exercise testing in patients with chronic thromboembolic pulmonary hypertension].","display_name":"[Application of cardiopulmonary exercise testing in patients with chronic thromboembolic pulmonary hypertension].","publication_year":2013,"publication_date":"2013-06-11","ids":{"openalex":"https://openalex.org/W36571649","mag":"36571649","pmid":"https://pubmed.ncbi.nlm.nih.gov/24124672"},"language":"zh","primary_location":{"id":"pmid:24124672","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24124672","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua yi xue za zhi","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110375334","display_name":"Zhihui Zhao","orcid":"https://orcid.org/0000-0002-8160-9365","observed_orcids":["https://orcid.org/0000-0002-8160-9365"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210161896","display_name":"Fu Wai Hospital","ror":"https://ror.org/0590dnz19","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161896"]},{"id":"https://openalex.org/I4391767941","display_name":"State Key Laboratory of Cardiovascular Disease","ror":"https://ror.org/00t7sjs72","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210087153","https://openalex.org/I4391767941"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-hui Zhao","raw_affiliation_strings":["State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210161896","https://openalex.org/I4391767941"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100328497","display_name":"Zhihong Liu","orcid":"https://orcid.org/0000-0001-8639-6306","observed_orcids":["https://orcid.org/0000-0001-8639-6306"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhi-hong Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100602744","display_name":"Qing Gu","orcid":"https://orcid.org/0000-0001-5394-6615","observed_orcids":["https://orcid.org/0000-0001-5394-6615"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing Gu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Qin Luo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qin Luo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Qing Zhao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing Zhao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110526839","display_name":"Changming Xiong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chang-ming Xiong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109461231","display_name":"Xin\u2010Hai Ni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xin-hai Ni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.475,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.69648625,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"93","issue":"22","first_page":"1687","last_page":"90"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.03869999945163727,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-thromboembolic-pulmonary-hypertension","display_name":"chronic thromboembolic pulmonary hypertension","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiopulmonary-exercise-testing","display_name":"cardiopulmonary exercise testing","score":0.9430000185966492},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.8920000195503235},{"id":"https://openalex.org/keywords/chronic-pulmonary-thromboembolism","display_name":"chronic pulmonary embolism","score":0.9710000157356262},{"id":"https://openalex.org/keywords/vo2max","display_name":"VO2max","score":0.7139999866485596},{"id":"https://openalex.org/keywords/anaerobic-threshold","display_name":"anaerobic threshold","score":0.8019999861717224},{"id":"https://openalex.org/keywords/oxygen-pulse","display_name":"oxygen pulse","score":0.6769999861717224},{"id":"https://openalex.org/keywords/dead-space-to-tidal-volume-ratio","display_name":"dead space to tidal volume ratio","score":0.7540000081062317},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.734000027179718},{"id":"https://openalex.org/keywords/exercise-capacity","display_name":"exercise capacity","score":0.4749999940395355},{"id":"https://openalex.org/keywords/right-ventricular-function","display_name":"right ventricular function","score":0.5820000171661377},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9126343727111816},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.6495844721794128},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6285309791564941},{"id":"https://openalex.org/C2776265017","wikidata":"https://www.wikidata.org/wiki/Q220570","display_name":"Pulmonary embolism","level":2,"score":0.6275547742843628},{"id":"https://openalex.org/C5140985","wikidata":"https://www.wikidata.org/wiki/Q483866","display_name":"Anaerobic exercise","level":2,"score":0.5924851894378662},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5752168297767639},{"id":"https://openalex.org/C2777014857","wikidata":"https://www.wikidata.org/wiki/Q1383410","display_name":"Exacerbation","level":2,"score":0.556756854057312},{"id":"https://openalex.org/C2777428986","wikidata":"https://www.wikidata.org/wiki/Q1958249","display_name":"Chronic thromboembolic pulmonary hypertension","level":3,"score":0.4740868806838989},{"id":"https://openalex.org/C196310339","wikidata":"https://www.wikidata.org/wiki/Q60354","display_name":"VO2 max","level":4,"score":0.45921918749809265},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.4570257365703583},{"id":"https://openalex.org/C2779916996","wikidata":"https://www.wikidata.org/wiki/Q56324884","display_name":"Pulmonary thromboendarterectomy","level":4,"score":0.41392290592193604},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.22968652844429016},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.22903957962989807},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.22500577569007874},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.1424209177494049}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011655","descriptor_name":"Pulmonary Embolism","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011655","descriptor_name":"Pulmonary Embolism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D011655","descriptor_name":"Pulmonary Embolism","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020097","descriptor_name":"Natriuretic Peptide, Brain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:24124672","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24124672","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua yi xue za zhi","raw_type":"English Abstract"},{"id":"mag:36571649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24124672","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1974121081","https://openalex.org/W2900212899","https://openalex.org/W2083127430","https://openalex.org/W3016479502","https://openalex.org/W2508866329","https://openalex.org/W2107200347","https://openalex.org/W1840378504","https://openalex.org/W2610215706","https://openalex.org/W2132367693","https://openalex.org/W1973324064","https://openalex.org/W2131770085","https://openalex.org/W2040916541","https://openalex.org/W2325391559","https://openalex.org/W2061400475","https://openalex.org/W2044892290","https://openalex.org/W1979689703","https://openalex.org/W185021453","https://openalex.org/W2010409600","https://openalex.org/W2037706047","https://openalex.org/W2061848844","https://openalex.org/W2930818970","https://openalex.org/W1990734709","https://openalex.org/W2031415599","https://openalex.org/W2103768332","https://openalex.org/W2155751987","https://openalex.org/W1992244239","https://openalex.org/W2144746508","https://openalex.org/W1967111938","https://openalex.org/W1885947760","https://openalex.org/W2053364971","https://openalex.org/W3008355211","https://openalex.org/W2164752107","https://openalex.org/W2153190846","https://openalex.org/W1982392408","https://openalex.org/W2143479593","https://openalex.org/W2792568232","https://openalex.org/W1971623513","https://openalex.org/W2021008728","https://openalex.org/W2604701538","https://openalex.org/W2900620364","https://openalex.org/W2623360428","https://openalex.org/W2953054776","https://openalex.org/W1986751494","https://openalex.org/W1979984125","https://openalex.org/W3004004129"],"related_works":["https://openalex.org/W2997334022","https://openalex.org/W4280585655","https://openalex.org/W7135396157","https://openalex.org/W4303710048","https://openalex.org/W1989427661","https://openalex.org/W2967501575","https://openalex.org/W2011838978","https://openalex.org/W2323268992","https://openalex.org/W3032337405","https://openalex.org/W824974013"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2,91,364],"the":[3,27,92,106,114,136,140,148,175,183,208,249,258,278,288,365],"application":[4],"value":[5],"of":[6,21,30,38,68,172,205,221,228,268,297,344,352,368],"cardiopulmonary":[7,77,354,366],"exercise":[8,78,355],"testing":[9,79,356],"in":[10,47,105,113,139,147,174,182,237,248,257,277,287],"patients":[11,24],"with":[12,302],"chronic":[13,48],"thromboembolic":[14],"pulmonary":[15,45,49,57,60],"hypertension":[16,46],"(CTEPH).":[17],"METHODS:":[18],"A":[19],"total":[20],"116":[22],"consecutive":[23],"admitted":[25],"into":[26,35],"Cardiology":[28],"Department":[29],"Fuwai":[31],"Hospital.They":[32],"were":[33,74,178,212,252,283,299,340],"divided":[34],"3":[36,88],"groups":[37,89,118,152,187,262,282],"CTEPH":[39,107,141,176,250,279,369],"(n":[40,51,62],"=":[41,52,63,308,311,316,319,327,330,335,338],"44),":[42],"CPE":[43,115,149,184,259,281],"(without":[44,56],"embolism)":[50],"24)":[53],"and":[54,90,96,116,126,150,160,185,195,210,245,260,280,313,332,361],"control":[55,117,151,186,261,289],"embolism":[58],"or":[59,219],"hypertension)":[61],"48)":[64,155],"respectively.":[65],"Their":[66],"levels":[67],"N-terminal":[69],"pro-brain":[70],"natriuretic":[71],"peptide":[72],"(NT-proBNP)":[73],"measured.":[75],"Incremental":[76],"was":[80,109,143],"performed":[81],"to":[82,239,273,363],"compare":[83],"its":[84,97],"differential":[85],"results":[86],"among":[87],"correlation":[93],"between":[94],"NT-proBNP":[95,173,298],"parameters.":[98],"RESULTS:":[99],"The":[100,169,266,294,321],"body":[101,240],"mass":[102],"index":[103],"(BMI)":[104],"group":[108,142,177,251,290],"lower":[110,254],"than":[111,145,180,255,285],"those":[112,146,181,256,286],"((23.8":[119],"\u00b1":[120,124,128,154,158,162,189,193,197],"3.9)":[121],"vs":[122,156,191],"(26.1":[123],"3.6)":[125],"(26.7":[127],"3.2)":[129],"kg/m(2)":[130],"),":[131],"both":[132,165,200],"P":[133,166,201,310,318,329,337],"<":[134,167,202,264,292],"0.05);":[135],"medical":[137],"history":[138],"longer":[144],"((58":[153],"(12":[157],"10)":[159],"(29":[161],"25)":[163],"months,":[164],"0.05).":[168,203,265,293],"plasma":[170,295],"concentrations":[171,296],"higher":[179,284],"((1678":[188],"1255)":[190],"(577":[192],"167)":[194],"(608":[196],"247)":[198],"pmol/L,":[199],"All":[204],"them":[206],"completed":[207],"test":[209],"there":[211],"no":[213],"severe":[214],"complications":[215],"such":[216],"as":[217],"syncope":[218],"exacerbation":[220],"disease.":[222],"Maximum":[223],"oxygen":[224,231,235],"consumption":[225,232,236],"(VO2max),":[226],"percentage":[227],"predicted":[229],"maximum":[230],"(VO2":[233],"%),":[234],"relation":[238],"weight":[241],"(VO2/kg),":[242],"anaerobic":[243],"threshold":[244],"O2":[246],"pulse":[247],"significantly":[253],"(P":[263,291],"ratios":[267],"dead":[269],"space":[270],"volume":[271,275],"(VD)":[272],"tidal":[274],"(VT)":[276],"inversely":[300],"correlated":[301],"right":[303,322],"ventricular":[304,323],"internal":[305,324],"diameter":[306,325],"(r":[307,315],"-0.690,":[309],"0.000)":[312,331],"VO2/kg":[314,333],"-0.496,":[317],"0.000).":[320],"(\u03b2":[326,334],"0.583,":[328],"0.233,":[336],"0.032)":[339],"strong":[341],"independent":[342],"determinants":[343],"NT-proBNP.":[345],"CONCLUSION:":[346],"As":[347],"a":[348],"reliable":[349],"pathophysiological":[350],"indictor":[351],"CTEPH,":[353],"may":[357],"be":[358],"used":[359],"objectively":[360],"safely":[362],"function":[367],"patients.":[370]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}