{"id":"https://openalex.org/W363908962","doi":null,"title":"[ Modeling of Genetic Risk Factors in Ischemic Stroke]","display_name":"[ Modeling of Genetic Risk Factors in Ischemic Stroke]","publication_year":2015,"publication_date":"2015-11-03","ids":{"openalex":"https://openalex.org/W363908962","mag":"363908962"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.681.7539","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.681.7539","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.issr-journals.org/links/papers.php?application%3Dpdf%26article%3DIJISR-14-150-05%26journal%3Dijisr","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009180311","display_name":"Khalid Balar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Khalid Balar","raw_affiliation_strings":["Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080286648","display_name":"Sellama Nadifi","orcid":"https://orcid.org/0000-0002-4272-1506","observed_orcids":["https://orcid.org/0000-0002-4272-1506"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Sellama Nadifi","raw_affiliation_strings":["Laboratory of Medical Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Medical Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033339476","display_name":"Khalil Hamzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Khalil Hamzi","raw_affiliation_strings":["Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001120487","display_name":"Brehima Diakit\u00e9","orcid":"https://orcid.org/0000-0001-8296-5292","observed_orcids":["https://orcid.org/0000-0001-8296-5292"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Br\u00e9hima Diakite","raw_affiliation_strings":["Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Human Genetics and Molecular Pathology,  University Hassan II/ Faculty of Medicine,    Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I99297268"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00544664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.6689000129699707,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.6689000129699707,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.20640000700950623,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.05609999969601631,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":1.0},{"id":"https://openalex.org/keywords/stroke-prediction","display_name":"stroke risk prediction","score":0.7110000252723694},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"logistic regression","score":0.7710000276565552},{"id":"https://openalex.org/keywords/case-control-study","display_name":"case-control study","score":0.6110000014305115},{"id":"https://openalex.org/keywords/predictive-value","display_name":"predictive value","score":0.47600001096725464},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.7862951159477234},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.6605894565582275},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6319195032119751},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5444941520690918},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.4635006785392761},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.4346754848957062},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.42483603954315186},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.42082297801971436},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3926495313644409},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3270498812198639},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2957151234149933},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1456102430820465},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.12546712160110474},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09871715307235718},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.681.7539","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.681.7539","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.issr-journals.org/links/papers.php?application%3Dpdf%26article%3DIJISR-14-150-05%26journal%3Dijisr","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2348349774","https://openalex.org/W2384581531","https://openalex.org/W3187834026","https://openalex.org/W3197331610","https://openalex.org/W2975696933","https://openalex.org/W2786022743","https://openalex.org/W4297184643","https://openalex.org/W4409896481","https://openalex.org/W2362473879","https://openalex.org/W3025277740"],"abstract_inverted_index":{"Copyright":[0],"\u00a9":[1],"2014":[2],"ISSR":[3],"Journals.":[4],"This":[5],"is":[6,32,206,239],"an":[7,82,107],"open":[8],"access":[9],"article":[10],"distributed":[11],"under":[12],"the":[13,29,44,69,73,76,115,122,134,149,155,160,169,185,188,191,198,229,233,242,246],"Creative":[14],"Commons":[15],"Attribution":[16],"License,":[17],"which":[18],"permits":[19],"unrestricted":[20],"use,":[21],"distribution,":[22],"and":[23,110,127,158,193,232,259],"reproduction":[24],"in":[25,61,66,81,121],"any":[26],"medium,":[27],"provided":[28],"original":[30],"work":[31,42],"properly":[33],"cited.":[34],"ABSTRACT:":[35],"In":[36,143],"this":[37],"article,":[38],"we":[39,71,128,147],"focus":[40],"our":[41,62,137,237],"on":[43,50,86,154,164],"modeling":[45],"of":[46,75,78,93,136,151,162,187,190,196,200,213,224,236],"genetic":[47,87],"risk":[48,88,156],"factors":[49,157],"ischemic":[51,79,108,204],"strokes":[52],"occurred.":[53],"To":[54],"do":[55],"this,":[56],"logistic":[57],"regression":[58],"was":[59],"widespread":[60],"study.":[63],"We":[64,113,172,226],"proceeded":[65],"two":[67],"stages:":[68],"first,":[70],"modeled":[72],"probability":[74],"occurrence":[77],"stroke":[80,109,166,205,218],"individual":[83],"(i)":[84],"based":[85],"factors.":[89],"Our":[90],"sample":[91],"consisted":[92],"330":[94],"individuals":[95],"aged":[96],"at":[97],"least":[98],"40":[99],"years,":[100],"divided":[101],"into":[102],"165":[103,111],"patients":[104],"who":[105,202],"had":[106],"controls.":[112],"applied":[114],"Wald":[116],"test":[117],"for":[118],"all":[119,141],"variables":[120,138,153,163],"model":[123,170,192,238,254],"one":[124,126],"by":[125],"concluded":[129],"to":[130,167,183],"Reject":[131],"H0,":[132],"since":[133],"coefficients":[135],"are":[139],"not":[140],"zero.":[142],"a":[144,174,220,251],"second":[145],"step,":[146],"studied":[148],"effects":[150],"these":[152],"then":[159],"effect":[161],"Ischemic":[165,217],"present":[168],"equation.":[171],"set":[173],"prediction":[175,230],"threshold":[176],"after":[177],"specification":[178],"test,":[179],"that":[180,211,228],"allows":[181],"us":[182],"ensure":[184],"quality":[186],"fit":[189],"its":[194],"degree":[195],"prediction,":[197],"proportion":[199],"people":[201,215],"have":[203],"(50%).":[207],"The":[208],"results":[209,243],"showed":[210],"128":[212],"156":[214],"with":[216,245,255],"allowed":[219],"positive":[221],"predictive":[222],"value":[223],"82%.":[225],"conclude":[227],"rate":[231,235],"success":[234],"80.30":[240],"%,":[241],"obtained":[244],"\u00abXLSTAT":[247],"\u00bb":[248],"software":[249],"show":[250],"very":[252],"good":[253],"(sensitivity":[256],"78":[257],"%":[258],"specificity":[260],"83%).":[261]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}