{"id":"https://openalex.org/W35891520","doi":"https://doi.org/10.1017/cbo9780511732263.009","title":"The importance of a quality assurance plan for method validation and minimizing uncertainties in the HPLC analysis of phytoplankton pigments","display_name":"The importance of a quality assurance plan for method validation and minimizing uncertainties in the HPLC analysis of phytoplankton pigments","publication_year":2011,"publication_date":"2011-10-27","ids":{"openalex":"https://openalex.org/W35891520","doi":"https://doi.org/10.1017/cbo9780511732263.009","mag":"35891520"},"language":"en","primary_location":{"id":"doi:10.1017/cbo9780511732263.009","doi":"https://doi.org/10.1017/cbo9780511732263.009","is_oa":false,"landing_page_url":"https://doi.org/10.1017/cbo9780511732263.009","pdf_url":null,"source":{"id":"https://openalex.org/S4306462995","display_name":"Cambridge University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytoplankton Pigments","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4302083355","display_name":"Phytoplankton Pigments"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019620374","display_name":"Laurie Van Heukelem","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laurie van Heukelem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111897973","display_name":"Stanford B. Hooker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stanford B. Hooker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9242,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.82969799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"195","last_page":"256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11890","display_name":"Scientific Measurement and Uncertainty Evaluation","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11890","display_name":"Scientific Measurement and Uncertainty Evaluation","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.04170000180602074,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10032","display_name":"Marine and coastal ecosystems","score":0.03700000047683716,"subfield":{"id":"https://openalex.org/subfields/1910","display_name":"Oceanography"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quality-assurance-plan","display_name":"quality assurance plan","score":0.9980000257492065},{"id":"https://openalex.org/keywords/method-validation","display_name":"method validation","score":0.925000011920929},{"id":"https://openalex.org/keywords/measurement-uncertainty","display_name":"measurement uncertainty","score":0.6309999823570251},{"id":"https://openalex.org/keywords/phytoplankton-pigments","display_name":"phytoplankton pigments","score":0.9869999885559082},{"id":"https://openalex.org/keywords/hplc-analysis","display_name":"HPLC assay","score":0.8930000066757202},{"id":"https://openalex.org/keywords/quality-control","display_name":"quality control","score":0.8820000290870667},{"id":"https://openalex.org/keywords/interlaboratory-comparison","display_name":"interlaboratory comparison","score":0.6549999713897705},{"id":"https://openalex.org/keywords/data-accuracy","display_name":"data accuracy","score":0.5659999847412109}],"concepts":[{"id":"https://openalex.org/C106436119","wikidata":"https://www.wikidata.org/wiki/Q836575","display_name":"Quality assurance","level":3,"score":0.6988369226455688},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.6042296886444092},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5843144655227661},{"id":"https://openalex.org/C2776505523","wikidata":"https://www.wikidata.org/wiki/Q4785468","display_name":"Plan (archaeology)","level":2,"score":0.5514829158782959},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.5410124659538269},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5158676505088806},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.49078139662742615},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.34892478585243225},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34296903014183044},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.33500808477401733},{"id":"https://openalex.org/C42475967","wikidata":"https://www.wikidata.org/wiki/Q194292","display_name":"Operations research","level":1,"score":0.32673490047454834},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.32093727588653564},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2421090006828308},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19506540894508362},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15839120745658875},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.1316983997821808},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.12757530808448792},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C2778618615","wikidata":"https://www.wikidata.org/wiki/Q4008393","display_name":"External quality assessment","level":2,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1017/cbo9780511732263.009","doi":"https://doi.org/10.1017/cbo9780511732263.009","is_oa":false,"landing_page_url":"https://doi.org/10.1017/cbo9780511732263.009","pdf_url":null,"source":{"id":"https://openalex.org/S4306462995","display_name":"Cambridge University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytoplankton Pigments","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1480376833","https://openalex.org/W1493470111","https://openalex.org/W1542162133","https://openalex.org/W1554944419","https://openalex.org/W1557141846","https://openalex.org/W1574789166","https://openalex.org/W1911272828","https://openalex.org/W1969501688","https://openalex.org/W1974529906","https://openalex.org/W1981641355","https://openalex.org/W2011455866","https://openalex.org/W2014857473","https://openalex.org/W2025430691","https://openalex.org/W2039800823","https://openalex.org/W2053834856","https://openalex.org/W2064745902","https://openalex.org/W2065431688","https://openalex.org/W2081106577","https://openalex.org/W2112412743","https://openalex.org/W2133731538","https://openalex.org/W2144239165","https://openalex.org/W2157676931","https://openalex.org/W2158569580","https://openalex.org/W2162694246","https://openalex.org/W2182304211","https://openalex.org/W2183171587","https://openalex.org/W2183540587","https://openalex.org/W2201685611","https://openalex.org/W2320070461","https://openalex.org/W2321983024","https://openalex.org/W2339331311","https://openalex.org/W2493929367","https://openalex.org/W2496273088","https://openalex.org/W2514460972","https://openalex.org/W2596399612","https://openalex.org/W2597524731","https://openalex.org/W2944147120","https://openalex.org/W3007864959","https://openalex.org/W3029455382","https://openalex.org/W3110476568","https://openalex.org/W4285719527","https://openalex.org/W6720611982","https://openalex.org/W6723491581","https://openalex.org/W6725925917"],"related_works":["https://openalex.org/W7015143030","https://openalex.org/W7048049241","https://openalex.org/W2349012444","https://openalex.org/W7028033844","https://openalex.org/W2099329253","https://openalex.org/W80791535","https://openalex.org/W2113506307","https://openalex.org/W2304975448","https://openalex.org/W7135530401","https://openalex.org/W4391875676"],"abstract_inverted_index":{"Introduction":[0],"A":[1,28,268],"quality":[2,38,43],"assurance":[3],"plan":[4],"(QAP)":[5],"describes":[6,49,70,246],"a":[7,60,68,76,80,93,110,162,172,249],"process":[8],"to":[9,57,83,91,130,166,179,275,284],"ensure":[10],"an":[11],"analytical":[12],"method":[13,36,61],"fulfils":[14],"the":[15,24,46,87,96,102,105,121,125,144,153,159,183,194,215,224,228,231,252,261,278,289],"agreed":[16],"upon":[17],"accuracy":[18,229,290],"objectives":[19],"at":[20],"all":[21,99,118],"points":[22],"during":[23,257],"analysis":[25,142],"of":[26,52,95,98,109,117,140,155,161,182,214,230,248,254,271,281],"samples.":[27],"QAP":[29,69,174,250],"includes":[30,171],"such":[31],"things":[32],"as":[33],"standardized":[34],"procedures,":[35],"validation,":[37],"control":[39],"(QC)":[40],"measurements,":[41],"and":[42,114,211,221,240,264],"assessment":[44],"(QA);":[45],"latter":[47],"quantitatively":[48],"how":[50],"results":[51],"QC":[53],"measurements":[54],"are":[55,204,217],"used":[56],"determine":[58,276],"whether":[59,169],"is":[62,89,151,177,199],"performing":[63],"within":[64],"expectations.":[65],"By":[66],"analogy,":[67],"what":[71],"can":[72],"be":[73,92],"considered,":[74],"in":[75,137,143,148,193,207,251],"more":[77],"general":[78],"sense,":[79],"\u2018holistic\u2019":[81],"approach":[82,165],"sample":[84,167],"analysis,":[85,168],"whereby":[86],"\u2018whole":[88],"considered":[90],"result":[94],"interdependence":[97,116],"parts\u2019.":[100],"Here,":[101],"\u2018whole\u2019":[103],"represents":[104,120],"overall":[106],"combined":[107],"uncertainty":[108,141],"final":[111,133],"data":[112,134,195,203,216,225,232],"product,":[113],"\u2018the":[115],"parts\u2019":[119],"uncertainties":[122,184],"contributed":[123],"by":[124,260],"many":[126],"individual":[127],"procedures":[128],"required":[129],"produce":[131],"that":[132],"product.":[135],"An":[136],"depth":[138],"discussion":[139],"chemical":[145],"laboratory,":[146],"given":[147],"EURACHEM":[149],"(2000),":[150],"beyond":[152],"scope":[154],"this":[156,170],"chapter,":[157],"but":[158],"importance":[160],"so-called":[163],"holistic":[164],"formalized":[173],"or":[175],"not,":[176],"necessary":[178],"provide":[180],"knowledge":[181,198,255],"associated":[185],"with":[186],"measured":[187],"values":[188],"and,":[189],"thus,":[190],"facilitate":[191],"confidence":[192],"products.":[196],"Such":[197],"important,":[200],"because":[201],"pigment":[202],"often":[205],"compiled":[206],"increasingly":[208],"large":[209],"databases,":[210],"end":[212],"users":[213],"remote":[218],"(in":[219],"space":[220],"time)":[222],"from":[223],"providers.":[226],"Knowing":[227],"facilitates":[233],"their":[234],"wider":[235],"utility,":[236],"for":[237,292],"both":[238],"current":[239],"unanticipated":[241],"future":[242],"applications.":[243],"This":[244],"chapter":[245],"components":[247],"context":[253],"gained":[256],"intercomparisons":[258],"sponsored":[259],"National":[262],"Aeronautics":[263],"Space":[265],"Administration":[266],"(NASA).":[267],"primary":[269],"objective":[270],"these":[272],"activities":[273],"was":[274],"if":[277],"myriad":[279],"providers":[280],"HPLC":[282],"analyses":[283],"NASA":[285],"researchers":[286],"were":[287],"satisfying":[288],"requirements":[291],"field":[293],"observations.":[294]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":6},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}