{"id":"https://openalex.org/W35071699","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","title":"The ral gene: a new ras related gene isolated by the use of a synthetic probe.","display_name":"The ral gene: a new ras related gene isolated by the use of a synthetic probe.","publication_year":1986,"publication_date":"1986-09-01","ids":{"openalex":"https://openalex.org/W35071699","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","mag":"35071699","pmid":"https://pubmed.ncbi.nlm.nih.gov/3023062","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167101"},"language":"en","primary_location":{"id":"doi:10.1002/j.1460-2075.1986.tb04485.x","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1986.tb04485.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1986.tb04485.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"P. Chardin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Chardin","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012973044","display_name":"Armand Tavitian","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Tavitian","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":8.3252,"has_fulltext":true,"cited_by_count":259,"citation_normalized_percentile":{"value":0.98454244,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"5","issue":"9","first_page":"2203","last_page":"2208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ras-related-proteins","display_name":"Ras-related proteins","score":0.6600000262260437},{"id":"https://openalex.org/keywords/ras-p21","display_name":"p21ras","score":0.7879999876022339},{"id":"https://openalex.org/keywords/g-proteins","display_name":"G proteins","score":0.8209999799728394},{"id":"https://openalex.org/keywords/synthetic-oligonucleotide-probes","display_name":"synthetic oligonucleotide probes","score":0.8379999995231628},{"id":"https://openalex.org/keywords/h-ras","display_name":"H-Ras","score":0.6119999885559082},{"id":"https://openalex.org/keywords/kras","display_name":"KRAS","score":0.996999979019165},{"id":"https://openalex.org/keywords/nras","display_name":"NRAS","score":0.9950000047683716},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.7210000157356262},{"id":"https://openalex.org/keywords/protein-homology","display_name":"protein homology","score":0.6179999709129333}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8972088098526001},{"id":"https://openalex.org/C165525559","wikidata":"https://www.wikidata.org/wiki/Q224180","display_name":"Homology (biology)","level":3,"score":0.6482439041137695},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5819570422172546},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.5345192551612854},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.5131774544715881},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.5073665976524353},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.490028977394104},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.4885447919368744},{"id":"https://openalex.org/C189482833","wikidata":"https://www.wikidata.org/wiki/Q869146","display_name":"cDNA library","level":4,"score":0.450540691614151},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.44639265537261963},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.4370577335357666},{"id":"https://openalex.org/C163181125","wikidata":"https://www.wikidata.org/wiki/Q408592","display_name":"GTPase-activating protein","level":4,"score":0.4297686815261841},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31899023056030273},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.2950206398963928},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.20506104826927185}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004262","descriptor_name":"DNA Restriction Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005813","descriptor_name":"Genes, Synthetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009838","descriptor_name":"Oligodeoxyribonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018631","descriptor_name":"ras Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.1460-2075.1986.tb04485.x","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1986.tb04485.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:167947","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1167101","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:3023062","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3023062","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1167101","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1167101/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/j.1460-2075.1986.tb04485.x","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1986.tb04485.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1986.tb04485.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W35071699.pdf","grobid_xml":"https://content.openalex.org/works/W35071699.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W643035040","https://openalex.org/W1513717105","https://openalex.org/W1745921889","https://openalex.org/W1783564364","https://openalex.org/W1869481189","https://openalex.org/W1940081151","https://openalex.org/W1965058394","https://openalex.org/W1972370363","https://openalex.org/W1978274173","https://openalex.org/W1980234539","https://openalex.org/W1988181486","https://openalex.org/W1995561930","https://openalex.org/W2001923549","https://openalex.org/W2022213176","https://openalex.org/W2035711855","https://openalex.org/W2042371773","https://openalex.org/W2049596148","https://openalex.org/W2056786827","https://openalex.org/W2057385958","https://openalex.org/W2058649415","https://openalex.org/W2063361805","https://openalex.org/W2075612889","https://openalex.org/W2078792023","https://openalex.org/W2083690533","https://openalex.org/W2084832908","https://openalex.org/W2087884848","https://openalex.org/W2089548087","https://openalex.org/W2093660936","https://openalex.org/W2093742326","https://openalex.org/W2094816576","https://openalex.org/W2138270253","https://openalex.org/W2149077527","https://openalex.org/W2165867884","https://openalex.org/W6602861011"],"related_works":["https://openalex.org/W4250031008","https://openalex.org/W981271480","https://openalex.org/W2004512194","https://openalex.org/W2190848597","https://openalex.org/W2002299218","https://openalex.org/W1989379237","https://openalex.org/W1998668727","https://openalex.org/W2078425071","https://openalex.org/W2034763031","https://openalex.org/W162732615"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}