{"id":"https://openalex.org/W347747586","doi":"https://doi.org/10.1023/a:1005875015011","title":"Discovery of cryptophycin-1 and BCN-183577: Examples of strategies and problems in the detection of antitumor activity in mice","display_name":"Discovery of cryptophycin-1 and BCN-183577: Examples of strategies and problems in the detection of antitumor activity in mice","publication_year":1997,"publication_date":"1997-09-01","ids":{"openalex":"https://openalex.org/W347747586","doi":"https://doi.org/10.1023/a:1005875015011","mag":"347747586","pmid":"https://pubmed.ncbi.nlm.nih.gov/9387043"},"language":"en","primary_location":{"id":"doi:10.1023/a:1005875015011","doi":"https://doi.org/10.1023/a:1005875015011","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1005875015011","pdf_url":null,"source":{"id":"https://openalex.org/S6037287","display_name":"Investigational New Drugs","issn_l":"0167-6997","issn":["0167-6997","1573-0646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigational New Drugs","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113456083","display_name":"Thomas H. Corbett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas H. Corbett","raw_affiliation_strings":["Department of Internal Medicine, Wayne State University, School of Medicine, Detroit, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Wayne State University, School of Medicine, Detroit, USA","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016427618","display_name":"Frederick A. Valeriote","orcid":"https://orcid.org/0000-0001-5796-0932","observed_orcids":["https://orcid.org/0000-0001-5796-0932"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick A. Valeriote","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018925731","display_name":"Lisa L. Demchik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa Demchik","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050877867","display_name":"Nancy Lowichik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Lowichik","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062952510","display_name":"Lisa Polin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa Polin","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044393096","display_name":"Chiab Panchapor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chiab Panchapor","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054986468","display_name":"Susan Pugh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Pugh","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052096952","display_name":"Kathryn White","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathryn White","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087943411","display_name":"Juiwanna Kushner","orcid":"https://orcid.org/0009-0006-9880-8703","observed_orcids":["https://orcid.org/0009-0006-9880-8703"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juiwanna Kushner","raw_affiliation_strings":["Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065685307","display_name":"James B. Rake","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James Rake","raw_affiliation_strings":["Sanofi Winthrop Research Division, Malvern"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Winthrop Research Division, Malvern","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000902500","display_name":"Mark P. Wentland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Wentland","raw_affiliation_strings":["Department of Chemistry, Rensselaer Polytechnic Inst., Troy, N.Y., USA","Department of Chemistry, Rensselaer Polytechnic Institute Troy, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Rensselaer Polytechnic Inst., Troy, N.Y., USA","institution_ids":["https://openalex.org/I165799507"]},{"raw_affiliation_string":"Department of Chemistry, Rensselaer Polytechnic Institute Troy, USA","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014833964","display_name":"Trimurtulu Golakoti","orcid":"https://orcid.org/0000-0002-2358-565X","observed_orcids":["https://orcid.org/0000-0002-2358-565X"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trimurtulu Golakoti","raw_affiliation_strings":["Department of Chemistry, University of Hawaii, Honolulu, HI, USA","Department of Chemistry, University of Hawaii, Honolulu, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]},{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009951799","display_name":"Carl Hetzel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carl Hetzel","raw_affiliation_strings":["Department of Chemistry, University of Hawaii, Honolulu, HI, USA","Department of Chemistry, University of Hawaii, Honolulu, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]},{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041066252","display_name":"Junichi Ogino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junichi Ogino","raw_affiliation_strings":["Department of Chemistry, University of Hawaii, Honolulu, HI, USA","Department of Chemistry, University of Hawaii, Honolulu, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]},{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110234579","display_name":"Gregory M. L. Patterson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory Patterson","raw_affiliation_strings":["Department of Chemistry, University of Hawaii, Honolulu, HI, USA","Department of Chemistry, University of Hawaii, Honolulu, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]},{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107595054","display_name":"Richard E. Moore","orcid":"https://orcid.org/0000-0002-5328-9018","observed_orcids":["https://orcid.org/0000-0002-5328-9018"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Moore","raw_affiliation_strings":["Department of Chemistry, University of Hawaii, Honolulu, HI, USA","Department of Chemistry, University of Hawaii, Honolulu, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]},{"raw_affiliation_string":"Department of Chemistry, University of Hawaii, Honolulu, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4690,"currency":"USD","value_usd":4690},"apc_paid":null,"fwci":0.4741,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.58663655,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"15","issue":"3","first_page":"207","last_page":"218"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.41920000314712524,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.41920000314712524,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.19699999690055847,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.07450000196695328,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thioxanthone","display_name":"thioxanthone","score":0.8650000095367432},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.7129999995231628},{"id":"https://openalex.org/keywords/intravenous-administration","display_name":"intravenous administration","score":0.6899999976158142},{"id":"https://openalex.org/keywords/route-of-administration","display_name":"route of administration","score":0.6259999871253967},{"id":"https://openalex.org/keywords/dosing-regimen","display_name":"dosing regimen","score":0.6439999938011169},{"id":"https://openalex.org/keywords/anticancer-drug-discovery","display_name":"anticancer drug discovery","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3693073093891144},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.34451624751091003},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3217317461967468},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2638320028781891}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010456","descriptor_name":"Peptides, Cyclic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013892","descriptor_name":"Thioxanthenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013892","descriptor_name":"Thioxanthenes","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D047630","descriptor_name":"Depsipeptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1005875015011","doi":"https://doi.org/10.1023/a:1005875015011","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1005875015011","pdf_url":null,"source":{"id":"https://openalex.org/S6037287","display_name":"Investigational New Drugs","issn_l":"0167-6997","issn":["0167-6997","1573-0646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigational New Drugs","raw_type":"journal-article"},{"id":"pmid:9387043","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9387043","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigational new drugs","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1885939596","display_name":"THERAPEUTICS OF NEW SOLID TUMOR ANTICANCER AGENTS","funder_award_id":"P01CA046560","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2477248716","display_name":null,"funder_award_id":"CA 46560","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4270342832","display_name":"DRUG DISCOVERY--ANTICANCER AGENTS FOR COLORECTAL CANCER","funder_award_id":"5u01ca045962-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4931549396","display_name":null,"funder_award_id":"CA45962","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G497553939","display_name":null,"funder_award_id":"CA-53001","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1997846715","https://openalex.org/W2003984058","https://openalex.org/W2006935259","https://openalex.org/W2017895237","https://openalex.org/W2019701027","https://openalex.org/W2038988557","https://openalex.org/W2081563133","https://openalex.org/W2103956033","https://openalex.org/W2104987742","https://openalex.org/W2157154128","https://openalex.org/W2410247077"],"related_works":["https://openalex.org/W41891866","https://openalex.org/W25117316","https://openalex.org/W2151838717","https://openalex.org/W210740910","https://openalex.org/W112097824","https://openalex.org/W2230645060","https://openalex.org/W63308448","https://openalex.org/W2784995797","https://openalex.org/W1980042937","https://openalex.org/W2171753436"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}