{"id":"https://openalex.org/W34625883","doi":null,"title":"The impact of pulmonary hypertension on outcomes of patients with low left ventricular ejection fraction: a propensity analysis.","display_name":"The impact of pulmonary hypertension on outcomes of patients with low left ventricular ejection fraction: a propensity analysis.","publication_year":2012,"publication_date":"2012-11-01","ids":{"openalex":"https://openalex.org/W34625883","mag":"34625883","pmid":"https://pubmed.ncbi.nlm.nih.gov/23409360"},"language":"en","primary_location":{"id":"pmid:23409360","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23409360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart valve disease","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016715625","display_name":"Changyong Yang","orcid":"https://orcid.org/0000-0002-9423-3176","observed_orcids":["https://orcid.org/0000-0002-9423-3176"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210161528","display_name":"Qilu Hospital of Shandong University","ror":"https://ror.org/056ef9489","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161528"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changyong Yang","raw_affiliation_strings":["Cardiovascular Surgery Department of Qilu Hospital of Shandong University, Jinan, China. xycyang@hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Surgery Department of Qilu Hospital of Shandong University, Jinan, China. xycyang@hotmail.com","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210161528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056179826","display_name":"Dadong Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dadong Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017341910","display_name":"Roger A Mennett","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roger Mennett","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087938852","display_name":"Jonathan A. Hammond","orcid":"https://orcid.org/0000-0002-9746-5167","observed_orcids":["https://orcid.org/0000-0002-9746-5167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonathan Hammond","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100368305","display_name":"Gong Zhang","orcid":"https://orcid.org/0009-0001-6180-3865","observed_orcids":["https://orcid.org/0009-0001-6180-3865","https://orcid.org/0000-0002-5079-2064"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gong Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100607045","display_name":"Donghui Chen","orcid":"https://orcid.org/0000-0002-9579-3677","observed_orcids":["https://orcid.org/0000-0002-9579-3677","https://orcid.org/0000-0003-2584-8609"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Donghui Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006645021","display_name":"Justin Lundbye","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Justin Lundbye","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111706158","display_name":"Robert C. Gallagher","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert Gallagher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.03,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.78905628,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"21","issue":"6","first_page":"767","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.4496999979019165,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.4496999979019165,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.35420000553131104,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.05490000173449516,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-hypertension","display_name":"pulmonary hypertension","score":1.0},{"id":"https://openalex.org/keywords/reduced-left-ventricular-ejection-fraction","display_name":"reduced left ventricular ejection fraction","score":0.9750000238418579},{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.8650000095367432},{"id":"https://openalex.org/keywords/in-hospital-mortality","display_name":"in-hospital mortality","score":0.9279999732971191},{"id":"https://openalex.org/keywords/long-term-survival","display_name":"long-term survival","score":0.765999972820282},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.9860000014305115},{"id":"https://openalex.org/keywords/preoperative-risk-factors","display_name":"preoperative risk factors","score":0.5789999961853027},{"id":"https://openalex.org/keywords/pulmonary-pressure","display_name":"pulmonary pressure","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9620380997657776},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.8765524625778198},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7392991185188293},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6156406402587891},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.6122820377349854},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.6006036400794983},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5110689401626587},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.47778400778770447},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.4219876825809479},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4190295934677124},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.415641725063324},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.39366406202316284}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001026","descriptor_name":"Coronary Artery Bypass","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D003237","descriptor_name":"Connecticut","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006348","descriptor_name":"Cardiac Surgical Procedures","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006348","descriptor_name":"Cardiac Surgical Procedures","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006349","descriptor_name":"Heart Valve Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006349","descriptor_name":"Heart Valve Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006349","descriptor_name":"Heart Valve Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006349","descriptor_name":"Heart Valve Diseases","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017052","descriptor_name":"Hospital Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D018487","descriptor_name":"Ventricular Dysfunction, Left","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057216","descriptor_name":"Propensity Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062186","descriptor_name":"Arterial Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:23409360","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23409360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart valve disease","raw_type":"Journal Article"},{"id":"mag:34625883","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23409360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1983867400","https://openalex.org/W2003952405","https://openalex.org/W2036202668","https://openalex.org/W2068224022","https://openalex.org/W2077204921","https://openalex.org/W2099738919","https://openalex.org/W2101755834","https://openalex.org/W2106649608","https://openalex.org/W2110832794","https://openalex.org/W2114347694","https://openalex.org/W2138400505","https://openalex.org/W2146142514","https://openalex.org/W2165940314","https://openalex.org/W2184408120","https://openalex.org/W2368606883","https://openalex.org/W2609317968","https://openalex.org/W2769945558","https://openalex.org/W2932479363","https://openalex.org/W3004925508","https://openalex.org/W3006177219"],"related_works":["https://openalex.org/W2954046044","https://openalex.org/W2811270169","https://openalex.org/W2016173867","https://openalex.org/W2980425098","https://openalex.org/W4380047324","https://openalex.org/W2588638837","https://openalex.org/W1983570815","https://openalex.org/W2158879154","https://openalex.org/W2801531605","https://openalex.org/W2998035601"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"AIM":[2],"OF":[3],"THE":[4],"STUDY:":[5],"Pulmonary":[6,229],"hypertension":[7,230],"(PH)":[8],"is":[9],"commonly":[10],"described":[11],"as":[12,180],"a":[13,23,54,64,84,116,124,147,208,239,256],"risk":[14],"factor":[15],"in":[16,51,93,202,236],"cardiac":[17,245],"surgery;":[18],"however,":[19],"the":[20,37,77,96,107,162,203,232,269,272],"effect":[21],"of":[22,66,259,271],"low":[24,55,240],"left":[25],"ventricular":[26],"ejection":[27],"fraction":[28],"(LVEF)":[29],"on":[30],"PH":[31,44,108,144,169,179,204,213,260],"has":[32],"not":[33],"been":[34],"assessed.":[35],"Hence,":[36],"study":[38],"aim":[39],"was":[40,74,99,165,214],"to":[41,140,150,216],"determine":[42],"whether":[43],"increases":[45],"operative":[46],"mortality":[47,164,186,197,224,235],"and":[48,61,122,131,193,234,263],"survival":[49],"outcome":[50],"patients":[52,69,95,109,145,170,237],"with":[53,70,238],"LVEF.":[56],"METHODS:":[57],"Between":[58],"January":[59],"2001":[60],"September":[62],"2009,":[63],"total":[65],"845":[67],"consecutive":[68],"LVEF":[71,118,241],"<":[72,87,113,129,136,155,172],"40%":[73],"enrolled":[75],"into":[76],"study.":[78],"Among":[79],"these":[80],"patients,":[81],"444":[82],"had":[83,115,123],"pulmonary":[85,97],"pressure":[86,98],"40":[88,103],"mmHg":[89],"(NPH":[90],"group),":[91],"while":[92,174],"401":[94],">":[100],"or":[101],"=":[102,120,188,226],"mmHg.":[104],"RESULTS:":[105],"Preoperatively,":[106],"were":[110,199,243],"older":[111],"(p":[112,119,128,135,154,171,187,225],"0.001),":[114,121,173],"lower":[117],"higher":[125,167,201],"logistic":[126,176,210],"EuroSCORE":[127],"0.001)":[130],"serum":[132],"creatinine":[133],"level":[134],"0.026)":[137],"when":[138],"compared":[139],"NPH":[141],"patients.":[142],"The":[143,190],"showed":[146],"greater":[148],"tendency":[149],"develop":[151],"postoperative":[152,264],"complications":[153],"0.001).":[156],"After":[157],"adjusting":[158],"by":[159],"propensity":[160],"score,":[161],"in-hospital":[163,185],"significantly":[166,200],"among":[168],"multivariate":[175],"regressions":[177],"revealed":[178],"an":[181,218],"independent":[182,219],"predictor":[183,220],"for":[184,221],"0.036).":[189],"12-,":[191],"36-,":[192],"60-month":[194],"follow":[195,222],"up":[196,223],"rates":[198],"group.":[205],"By":[206],"using":[207],"Cox":[209],"regression":[211],"model,":[212],"shown":[215],"be":[217],"0.035).":[227],"CONCLUSION:":[228],"increased":[231],"morbidity":[233],"who":[242],"undergoing":[244],"surgery.":[246],"Future":[247],"studies":[248],"may":[249,253],"identify":[250],"subgroups":[251],"that":[252],"benefit":[254],"from":[255],"preoperative":[257],"optimization":[258],"and/or":[261],"intra-":[262],"therapies":[265],"directed":[266],"at":[267],"minimizing":[268],"effects":[270],"condition.":[273]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}