{"id":"https://openalex.org/W344983987","doi":null,"title":"Effects of Vitamins C and E Supplementation on Muscle Damage and Oxidative Stress in Female Athletes: A Double-Blind Clinical Trial","display_name":"Effects of Vitamins C and E Supplementation on Muscle Damage and Oxidative Stress in Female Athletes: A Double-Blind Clinical Trial","publication_year":2013,"publication_date":"2013-02-01","ids":{"openalex":"https://openalex.org/W344983987","mag":"344983987"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:e0ebaa6f4c5247259d5986a740dd5430","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e0ebaa6f4c5247259d5986a740dd5430","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0645\u062c\u0644\u0647 \u062f\u0627\u0646\u0634\u06a9\u062f\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0627\u0635\u0641\u0647\u0627\u0646, Vol 30, Iss 216, Pp 2113-2124 (2013)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/e0ebaa6f4c5247259d5986a740dd5430","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036026369","display_name":"Maryam Taghiyar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Maryam Taghiyar","raw_affiliation_strings":["MSc Student, Department of Community Nutrition, School of Food Science and Nutrition AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MSc Student, Department of Community Nutrition, School of Food Science and Nutrition AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013514020","display_name":"Reza Ghiasvand","orcid":"https://orcid.org/0000-0002-0755-2575","observed_orcids":["https://orcid.org/0000-0002-0755-2575","https://orcid.org/0000-0002-2203-8670"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Reza Ghiasvand","raw_affiliation_strings":["Assistant Professor, Department of Community Nutrition, School of Food Science and Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Community Nutrition, School of Food Science and Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016811241","display_name":"Awat Feizi","orcid":"https://orcid.org/0000-0002-1930-0340","observed_orcids":["https://orcid.org/0000-0002-1930-0340"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Awat Feizi","raw_affiliation_strings":["Assistant Professor, Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000527917","display_name":"Gholamreza Askari","orcid":"https://orcid.org/0000-0003-1194-9687","observed_orcids":["https://orcid.org/0000-0003-1194-9687","https://orcid.org/0000-0002-1390-4987"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Gholamreza Askari","raw_affiliation_strings":["Assistant Professor, Department of Community Nutrition, School of Food Science and Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Community Nutrition, School of Food Science and Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011614422","display_name":"Nafiseh Shokri Mashhadi","orcid":"https://orcid.org/0000-0003-4967-4412","observed_orcids":["https://orcid.org/0000-0003-4967-4412"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Nafiseh Shokri","raw_affiliation_strings":["MSc Student, Department of Community Nutrition, School of Food Science and Nutrition AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MSc Student, Department of Community Nutrition, School of Food Science and Nutrition AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I114982161"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-c-supplementation","display_name":"vitamin C supplementation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/vitamin-e-supplementation","display_name":"vitamin E supplementation","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6639999747276306},{"id":"https://openalex.org/keywords/exercise-induced-muscle-damage","display_name":"exercise-induced muscle damage","score":0.9639999866485596},{"id":"https://openalex.org/keywords/female-athletes","display_name":"female athletes","score":0.9330000281333923},{"id":"https://openalex.org/keywords/creatine-kinase","display_name":"creatine kinase","score":0.9599999785423279},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8489999771118164},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.7250000238418579},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.7059999704360962},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.8190000057220459},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":1.0}],"concepts":[{"id":"https://openalex.org/C2781054738","wikidata":"https://www.wikidata.org/wiki/Q4813730","display_name":"Athletes","level":2,"score":0.7946077585220337},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7350815534591675},{"id":"https://openalex.org/C2991744798","wikidata":"https://www.wikidata.org/wiki/Q608510","display_name":"Double blind","level":4,"score":0.7131271362304688},{"id":"https://openalex.org/C2993817360","wikidata":"https://www.wikidata.org/wiki/Q692536","display_name":"Muscle damage","level":2,"score":0.5492007732391357},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4518049955368042},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.44298380613327026},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4386264383792877},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.424900621175766},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3428557515144348},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09366816282272339},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.07822200655937195},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.07407581806182861}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:e0ebaa6f4c5247259d5986a740dd5430","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e0ebaa6f4c5247259d5986a740dd5430","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0645\u062c\u0644\u0647 \u062f\u0627\u0646\u0634\u06a9\u062f\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0627\u0635\u0641\u0647\u0627\u0646, Vol 30, Iss 216, Pp 2113-2124 (2013)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:e0ebaa6f4c5247259d5986a740dd5430","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e0ebaa6f4c5247259d5986a740dd5430","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0645\u062c\u0644\u0647 \u062f\u0627\u0646\u0634\u06a9\u062f\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0627\u0635\u0641\u0647\u0627\u0646, Vol 30, Iss 216, Pp 2113-2124 (2013)","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W143312124","https://openalex.org/W1248714233","https://openalex.org/W1532253775","https://openalex.org/W1978489775","https://openalex.org/W1999681825","https://openalex.org/W2011988006","https://openalex.org/W2018627567","https://openalex.org/W2019385148","https://openalex.org/W2028194205","https://openalex.org/W2031885663","https://openalex.org/W2033882509","https://openalex.org/W2042558624","https://openalex.org/W2056952663","https://openalex.org/W2071919332","https://openalex.org/W2111322855","https://openalex.org/W2122653386","https://openalex.org/W2139318467","https://openalex.org/W2145618172","https://openalex.org/W2155043864","https://openalex.org/W2158904838","https://openalex.org/W2166192262","https://openalex.org/W2166667442","https://openalex.org/W2275623742","https://openalex.org/W2337457656","https://openalex.org/W2417523176","https://openalex.org/W2494422311"],"related_works":["https://openalex.org/W1927406501","https://openalex.org/W1573371708","https://openalex.org/W4308351986","https://openalex.org/W4220681562","https://openalex.org/W6981384669","https://openalex.org/W4223912634","https://openalex.org/W2468327834","https://openalex.org/W4229375295","https://openalex.org/W2042670661","https://openalex.org/W2887359282"],"abstract_inverted_index":{"Background:":[0],"The":[1,72],"need":[2],"for":[3],"energy":[4],"in":[5,52,69,152,166,176,184,190,212],"strenuous":[6],"exercises":[7],"necessitates":[8],"increased":[9,14],"oxygen":[10,18],"consumption":[11],"and":[12,25,43,49,80,94,96,103,117,120,194,206],"hence":[13],"production":[15],"of":[16,40,138],"reactive":[17],"species.":[19],"It":[20],"seems":[21],"that":[22],"vitamins":[23,41,92,204],"C":[24,42,83,93,193,205],"E":[26,44,87,207],"supplementation":[27,45,208],"reduces":[28],"exercise-induced":[29],"oxidative":[30,50],"stress.":[31],"Therefore,":[32],"this":[33],"study":[34,140],"aimed":[35],"to":[36,77,107,201],"investigate":[37],"the":[38,105,136,139],"effects":[39],"on":[46],"muscle":[47,109,124,214],"damage":[48,110,125,215],"stress":[51],"female":[53,65],"athletes.":[54],"Methods:":[55],"This":[56],"four-week":[57],"randomized,":[58],"double-blind":[59],"clinical":[60],"trial,":[61],"recruited":[62],"64":[63],"trained":[64],"athletes":[66],"from":[67],"gyms":[68],"Isfahan,":[70],"Iran.":[71],"subjects":[73],"were":[74,100,164,173,187],"randomly":[75],"assigned":[76],"groups":[78,134,191],"A-D":[79],"received":[81],"vitamin":[82,86],"(250":[84],"mg/day),":[85],"(400":[88],"international":[89],"units),":[90],"both":[91],"E,":[95,226],"placebo.":[97],"Blood":[98],"samples":[99],"obtained":[101],"before":[102],"after":[104],"intervention":[106],"measure":[108],"indices,":[111,126],"i.e.":[112],"aspartate":[113,167],"transaminase,":[114],"creatine":[115,128,148],"kinase,":[116],"lactate":[118],"dehydrogenase,":[119],"malondialdehyde.":[121],"Findings:":[122],"Among":[123],"only":[127],"kinase":[129,149],"levels":[130,172,186],"significantly":[131,150,174],"reduced":[132],"between":[133,161],"at":[135],"end":[137],"(P":[141,155,179,196],"=":[142,156,180],"0.030).":[143],"Considering":[144],"within":[145,159],"group":[146,153,162,177],"differences,":[147],"decreased":[151,175],"A":[154],"0.002).":[157],"No":[158],"or":[160],"differences":[163],"observed":[165],"aminotransferase":[168],"levels.":[169],"Lactate":[170],"dehydrogenase":[171],"B":[178],"0.020).":[181],"Significant":[182],"reductions":[183],"malondialdehyde":[185],"also":[188],"detected":[189],"A,":[192],"D":[195],"<":[197],"0.05).":[198],"Conclusion:":[199],"According":[200],"our":[202],"findings,":[203],"can":[209],"be":[210],"beneficial":[211],"reducing":[213],"indices":[216],"during":[217],"aerobic":[218],"exercises.":[219],"Keywords:":[220],"Oxidative":[221],"stress,":[222],"Vitamin":[223,225],"C,":[224],"Supplementation,":[227],"Female":[228],"athlete,":[229],"Muscle":[230],"damage,":[231],"Clinical":[232],"trial":[233]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}