{"id":"https://openalex.org/W34247607","doi":null,"title":"Transscleral freezing of the retina: an experimental study.","display_name":"Transscleral freezing of the retina: an experimental study.","publication_year":1965,"publication_date":"1965-10-01","ids":{"openalex":"https://openalex.org/W34247607","mag":"34247607","pmid":"https://pubmed.ncbi.nlm.nih.gov/5831992"},"language":"en","primary_location":{"id":"pmid:5831992","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5831992","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029892911","display_name":"P L Archambeau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P L Archambeau","raw_affiliation_strings":["Section of Ophthalmology, Mayo Clinic and Mayo Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Ophthalmology, Mayo Clinic and Mayo Foundation","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108536202","display_name":"John W. Henderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4210120349","display_name":"University of Minnesota Rochester","ror":"https://ror.org/02rh4fw73","country_code":"US","type":"education","lineage":["https://openalex.org/I4210120349"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J W Henderson","raw_affiliation_strings":["Ophthalmology in the Mayo Graduate School of Medicine (University of Minnesota), Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology in the Mayo Graduate School of Medicine (University of Minnesota), Rochester, Minn","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210120349"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4666,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.84627869,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"5","first_page":"885","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.6333000063896179,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.6333000063896179,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11377","display_name":"Retinal and Macular Surgery","score":0.2849000096321106,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryoprobe","display_name":"cryoprobe","score":0.703000009059906},{"id":"https://openalex.org/keywords/retinal-lesions","display_name":"retinal lesions","score":0.5680000185966492},{"id":"https://openalex.org/keywords/freezing-time","display_name":"freezing time","score":0.7419999837875366},{"id":"https://openalex.org/keywords/freezing-point","display_name":"freezing point","score":0.7639999985694885},{"id":"https://openalex.org/keywords/glycerol","display_name":"glycerol","score":0.7039999961853027},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.32100000977516174}],"concepts":[{"id":"https://openalex.org/C2777100477","wikidata":"https://www.wikidata.org/wiki/Q193107","display_name":"Sclera","level":2,"score":0.8398832678794861},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.73891681432724},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.7281821966171265},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.7142021059989929},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.6038067936897278},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5103966593742371},{"id":"https://openalex.org/C2780428090","wikidata":"https://www.wikidata.org/wiki/Q625164","display_name":"Retinal detachment","level":3,"score":0.4906069338321686},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.37677696347236633},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2741270065307617},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21722641587257385},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002825","descriptor_name":"Chorioretinitis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003228","descriptor_name":"Conjunctiva","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003452","descriptor_name":"Cryosurgery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005615","descriptor_name":"Freezing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009887","descriptor_name":"Ophthalmoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012590","descriptor_name":"Sclera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:5831992","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5831992","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology","raw_type":"Journal Article"},{"id":"mag:34247607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5831992","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1521261103","https://openalex.org/W1975248000","https://openalex.org/W1979277752","https://openalex.org/W1990076998","https://openalex.org/W1990113030","https://openalex.org/W2000238137","https://openalex.org/W2006090135","https://openalex.org/W2013341341","https://openalex.org/W2021142147","https://openalex.org/W2023045244","https://openalex.org/W2037269254","https://openalex.org/W2043231560","https://openalex.org/W2044170759","https://openalex.org/W2068027757","https://openalex.org/W2077209662","https://openalex.org/W2079898404","https://openalex.org/W2096120878","https://openalex.org/W2105925569","https://openalex.org/W2118583749","https://openalex.org/W2122949811","https://openalex.org/W2134551201","https://openalex.org/W2135308878","https://openalex.org/W2144120780","https://openalex.org/W2145615553","https://openalex.org/W2147808390","https://openalex.org/W2151424793","https://openalex.org/W2196323576","https://openalex.org/W2270928010","https://openalex.org/W2284521680","https://openalex.org/W2341631570","https://openalex.org/W2343559692","https://openalex.org/W2394942924","https://openalex.org/W2417408395","https://openalex.org/W2470592829","https://openalex.org/W2522057813","https://openalex.org/W2736764896","https://openalex.org/W2917129950","https://openalex.org/W2974994486","https://openalex.org/W3121004873","https://openalex.org/W4244080777","https://openalex.org/W4246725659","https://openalex.org/W4296896314"],"related_works":["https://openalex.org/W1964823036","https://openalex.org/W2387505865","https://openalex.org/W2994708667","https://openalex.org/W4300328268","https://openalex.org/W2151167151","https://openalex.org/W2440479489","https://openalex.org/W2616055041","https://openalex.org/W4242941679","https://openalex.org/W2087575558","https://openalex.org/W1994937016"],"abstract_inverted_index":{"Transscleral":[0],"freezing":[1,26,46,60,112],"of":[2,25,30,47,65,111,125,165],"the":[3,23,28,38,45,57,63,66,123,126],"dogs":[4],"retina":[5],"for":[6,132],"2":[7,133],"seconds":[8,134],"icas":[9],"done":[10],"experimentally":[11],"and":[12,15,72,86,98,156,162],"demonstrated":[13],"ophthalmoscopically":[14],"histologically.":[16],"The":[17,50,91,101],"residling":[18],"lesion":[19,39,92],"was":[20,53,69,79,93],"studied":[21],"from":[22],"instant":[24],"to":[27,36,43,55,95,114,129],"stage":[29],"final":[31],"healing.":[32],"Attempts":[33],"were":[34],"made":[35],"alter":[37],"by":[40],"methods":[41],"known":[42],"affect":[44],"live":[48],"tissue.":[49],"Cooper-Linde":[51],"cryoprobe":[52],"used":[54],"produce":[56],"lesions.":[58],"Retinal":[59,105],"occurred":[61],"when":[62],"temperature":[64,124],"probe":[67,127],"tip":[68,128],"between":[70],"-30":[71],"-40\u00b0":[73],"C.":[74,131],"Adhesive":[75],"chorioretinitis":[76],"involving":[77],"sclera":[78],"observed,":[80],"first":[81],"evident":[82],"in":[83,88,139],"4":[84],"days,":[85],"healed":[87],"7":[89],"days.":[90],"resistant":[94],"retinal":[96,140,153],"separation":[97],"without":[99],"hemorrhage.":[100],"conjunctiva":[102],"appeared":[103],"unaffected.":[104],"destruction":[106,154],"increased":[107,109,152],"with":[108,117,145],"duration":[110],"up":[113],"20":[115],"seconds,":[116],"little":[118,143],"further":[119],"damage":[120],"thereafter.":[121],"Decreasing":[122],"-60\u00b0":[130],"caused":[135],"a":[136],"marked":[137],"increase":[138],"destruction,":[141],"but":[142],"change":[144],"longer":[146],"durations":[147],"at":[148],"that":[149],"temperature.":[150],"Refreezing":[151],"slightly":[155],"choroidal":[157],"reaction":[158],"markedly.":[159],"Rapid":[160],"thawing":[161],"subconjunctival":[163],"injection":[164],"glycerol":[166],"had":[167],"no":[168],"effect.":[169]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}