{"id":"https://openalex.org/W340939352","doi":null,"title":"Control of hypereosinophilic syndrome-associated recalcitrant coronary artery spasm by combined treatment with prednisone, imatinib mesylate and hydroxyurea.","display_name":"Control of hypereosinophilic syndrome-associated recalcitrant coronary artery spasm by combined treatment with prednisone, imatinib mesylate and hydroxyurea.","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W340939352","mag":"340939352","pmid":"https://pubmed.ncbi.nlm.nih.gov/18651015","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2274835"},"language":"en","primary_location":{"id":"pmid:18651015","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18651015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and clinical cardiology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2274835/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087836105","display_name":"Joseph H. Butterfield","orcid":"https://orcid.org/0000-0002-6830-2190","observed_orcids":["https://orcid.org/0000-0002-6830-2190"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph H Butterfield","raw_affiliation_strings":["Division of Allergic Diseases, Mayo Clinic, Rochester"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergic Diseases, Mayo Clinic, Rochester","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039995472","display_name":"Scott W. Sharkey","orcid":"https://orcid.org/0000-0002-7678-1742","observed_orcids":["https://orcid.org/0000-0002-7678-1742"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott W Sharkey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3831,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.63883542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"11","issue":"1","first_page":"25","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypereosinophilic-syndrome","display_name":"hypereosinophilic syndrome","score":1.0},{"id":"https://openalex.org/keywords/coronary-spasm","display_name":"coronary vasospasm","score":0.9940000176429749},{"id":"https://openalex.org/keywords/prednisone","display_name":"prednisone","score":0.8539999723434448},{"id":"https://openalex.org/keywords/imatinib-mesylate","display_name":"imatinib mesylate","score":1.0},{"id":"https://openalex.org/keywords/hydroxyurea","display_name":"hydroxyurea","score":1.0},{"id":"https://openalex.org/keywords/interferon-alpha-2b","display_name":"interferon alfa-2b","score":0.871999979019165},{"id":"https://openalex.org/keywords/cardiac-arrest","display_name":"cardiac arrest","score":0.9240000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9490318298339844},{"id":"https://openalex.org/C2777621362","wikidata":"https://www.wikidata.org/wiki/Q2551272","display_name":"Hypereosinophilic syndrome","level":3,"score":0.8243849277496338},{"id":"https://openalex.org/C2779084869","wikidata":"https://www.wikidata.org/wiki/Q505142","display_name":"Hypereosinophilia","level":3,"score":0.6858701109886169},{"id":"https://openalex.org/C2778720950","wikidata":"https://www.wikidata.org/wiki/Q424972","display_name":"Prednisone","level":2,"score":0.6842248439788818},{"id":"https://openalex.org/C3019892230","wikidata":"https://www.wikidata.org/wiki/Q177094","display_name":"Imatinib mesylate","level":4,"score":0.6619552969932556},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6120429635047913},{"id":"https://openalex.org/C2777129736","wikidata":"https://www.wikidata.org/wiki/Q505142","display_name":"Eosinophilia","level":2,"score":0.6016344428062439},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.570630669593811},{"id":"https://openalex.org/C2778704086","wikidata":"https://www.wikidata.org/wiki/Q693058","display_name":"Chest pain","level":2,"score":0.5614893436431885},{"id":"https://openalex.org/C2780581156","wikidata":"https://www.wikidata.org/wiki/Q112670","display_name":"Systemic mastocytosis","level":3,"score":0.4345468282699585},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.35744816064834595},{"id":"https://openalex.org/C2777583451","wikidata":"https://www.wikidata.org/wiki/Q177094","display_name":"Imatinib","level":3,"score":0.33008328080177307},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.327267587184906},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:18651015","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18651015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and clinical cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2274835","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2274835/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exp Clin Cardiol","raw_type":"Text"},{"id":"mag:340939352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18651015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2274835","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2274835/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exp Clin Cardiol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W81345852","https://openalex.org/W102911073","https://openalex.org/W289163878","https://openalex.org/W1890719904","https://openalex.org/W1908365115","https://openalex.org/W1966982322","https://openalex.org/W1968147012","https://openalex.org/W1976116359","https://openalex.org/W1979349818","https://openalex.org/W1998549792","https://openalex.org/W1998707857","https://openalex.org/W2006397845","https://openalex.org/W2012747721","https://openalex.org/W2012952884","https://openalex.org/W2015787372","https://openalex.org/W2020162693","https://openalex.org/W2025715150","https://openalex.org/W2029536308","https://openalex.org/W2032051733","https://openalex.org/W2034284623","https://openalex.org/W2036047439","https://openalex.org/W2040030594","https://openalex.org/W2045298729","https://openalex.org/W2048129963","https://openalex.org/W2048942545","https://openalex.org/W2049752920","https://openalex.org/W2064244980","https://openalex.org/W2078398386","https://openalex.org/W2080309999","https://openalex.org/W2080835865","https://openalex.org/W2081341576","https://openalex.org/W2093548393","https://openalex.org/W2103455454","https://openalex.org/W2111914345","https://openalex.org/W2114465654","https://openalex.org/W2115455779","https://openalex.org/W2118530465","https://openalex.org/W2239710658"],"related_works":["https://openalex.org/W4234716748","https://openalex.org/W4396913572","https://openalex.org/W2400762924","https://openalex.org/W4411131862","https://openalex.org/W2094439905","https://openalex.org/W2768545920","https://openalex.org/W4313559542","https://openalex.org/W7171776780","https://openalex.org/W2601337758","https://openalex.org/W2072786030"],"abstract_inverted_index":{"Uncontrolled":[0],"hypereosinophilic":[1,23,55],"syndrome":[2,24,56],"is":[3,172],"frequently":[4],"associated":[5,33,53],"with":[6,22,54],"cardiovascular":[7],"consequences":[8],"that":[9,167],"cause":[10],"significant":[11],"morbidity":[12],"and":[13,32,59,83,118,130,136,166],"mortality.":[14],"The":[15,64,146],"present":[16,151],"article":[17],"reports":[18],"on":[19],"a":[20,122],"patient":[21],"in":[25,94,155],"whom":[26],"recurrent,":[27],"recalcitrant":[28],"coronary":[29,140,163],"artery":[30,141,164],"spasm":[31,142,165],"cardiac":[34,39,50,60],"arrest":[35],"were":[36,57],"the":[37,95,101,109,134,150],"predominant":[38],"manifestations.":[40],"No":[41],"valvular":[42],"abnormalities,":[43],"evidence":[44,85],"of":[45,77,86,103,115,124,139,149,170],"mural":[46],"thrombi":[47],"or":[48,88],"other":[49,89],"findings":[51],"commonly":[52],"detected,":[58],"function":[61],"remained":[62],"normal.":[63],"serum":[65],"tryptase":[66],"level":[67],"was":[68,81,92,106,119],"normal,":[69],"cysteine-rich":[70],"hydrophobic":[71],"domain":[72],"2":[73],"(CHIC2)":[74],"deletion":[75],"analysis":[76],"bone":[78,96],"marrow":[79],"cells":[80],"negative":[82],"no":[84],"mastocytosis":[87],"hematological":[90],"disorder":[91],"found":[93],"marrow.":[97],"To":[98],"allow":[99],"for":[100],"reduction":[102],"prednisone,":[104],"interferon-alpha-2b":[105],"added":[107],"to":[108],"patient's":[110],"program,":[111],"but":[112],"caused":[113],"aggravation":[114],"chest":[116],"pain":[117],"discontinued.":[120],"However,":[121],"combination":[123],"reduced":[125],"prednisone":[126],"dosage,":[127],"imatinib":[128],"mesylate":[129],"hydroxyurea":[131],"successfully":[132],"controlled":[133],"eosinophilia,":[135],"thereafter,":[137],"episodes":[138],"did":[143],"not":[144],"recur.":[145],"clinical":[147],"features":[148],"case":[152],"suggest":[153],"that,":[154],"some":[156],"patients,":[157],"hypereosinophilia":[158],"may":[159],"manifest":[160],"as":[161],"resistant":[162],"aggressive":[168],"control":[169],"eosinophilia":[171],"necessary.":[173]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}