{"id":"https://openalex.org/W333429","doi":"https://doi.org/10.1007/978-2-8178-0761-4_20","title":"Roles of Polymorphonuclear Leukocytes in Focal Cerebral Ischemia","display_name":"Roles of Polymorphonuclear Leukocytes in Focal Cerebral Ischemia","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W333429","doi":"https://doi.org/10.1007/978-2-8178-0761-4_20","mag":"333429"},"language":"en","primary_location":{"id":"doi:10.1007/978-2-8178-0761-4_20","doi":"https://doi.org/10.1007/978-2-8178-0761-4_20","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-2-8178-0761-4_20","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Basis for Microcirculatory Disorders","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1500022372","display_name":"Molecular Basis for Microcirculatory Disorders"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111736311","display_name":"Gregory J. del Zoppo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. del Zoppo","raw_affiliation_strings":["The Scripps Research Institute, La Jolla, USA","THE SCRIPPS RESEARCH INSTITUTE;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, USA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"THE SCRIPPS RESEARCH INSTITUTE;","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036008306","display_name":"John M. Hallenbeck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Hallenbeck","raw_affiliation_strings":["The Scripps Research Institute, La Jolla, USA","THE SCRIPPS RESEARCH INSTITUTE;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, USA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"THE SCRIPPS RESEARCH INSTITUTE;","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108399665","display_name":"Julio Herrero Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julio H. Garcia","raw_affiliation_strings":["The Scripps Research Institute, La Jolla, USA","THE SCRIPPS RESEARCH INSTITUTE;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, USA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"THE SCRIPPS RESEARCH INSTITUTE;","institution_ids":["https://openalex.org/I123431417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I123431417"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"379","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.600600004196167,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.600600004196167,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.25850000977516174,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.09570000320672989,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polymorphonuclear-leukocytes","display_name":"polymorphonuclear leukocytes","score":0.9900000095367432},{"id":"https://openalex.org/keywords/focal-cerebral-ischemia","display_name":"focal cerebral ischemia","score":0.8920000195503235},{"id":"https://openalex.org/keywords/leukocyte-extravasation","display_name":"leukocyte transmigration","score":0.5709999799728394},{"id":"https://openalex.org/keywords/microvascular-inflammation","display_name":"microvascular inflammation","score":0.609000027179718},{"id":"https://openalex.org/keywords/basement-membrane-integrity","display_name":"basement membrane integrity","score":0.6589999794960022},{"id":"https://openalex.org/keywords/matrix-metalloproteinases","display_name":"matrix metalloproteinases","score":0.7760000228881836},{"id":"https://openalex.org/keywords/plasminogen-activator","display_name":"plasminogen activator","score":0.7979999780654907},{"id":"https://openalex.org/keywords/endothelial-activation","display_name":"endothelial activation","score":0.6800000071525574},{"id":"https://openalex.org/keywords/astrocyte-ultrastructure","display_name":"astrocyte ultrastructure","score":0.753000020980835},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.8299999833106995},{"id":"https://openalex.org/keywords/middle-cerebral-artery-occlusion","display_name":"middle cerebral artery occlusion","score":0.9100000262260437},{"id":"https://openalex.org/keywords/ischemic-neuronal-injury","display_name":"ischemic neuronal injury","score":0.6309999823570251},{"id":"https://openalex.org/keywords/leukocyte-infiltration","display_name":"leukocyte infiltration","score":0.335999995470047}],"concepts":[{"id":"https://openalex.org/C2776436680","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microvessel","level":3,"score":0.7946522235870361},{"id":"https://openalex.org/C2779333224","wikidata":"https://www.wikidata.org/wiki/Q809756","display_name":"Basal lamina","level":3,"score":0.7149292230606079},{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.5966486930847168},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5401841998100281},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.5205215215682983},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.4711436331272125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45830631256103516},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.45775118470191956},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4494313597679138},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.43165040016174316},{"id":"https://openalex.org/C2778820722","wikidata":"https://www.wikidata.org/wiki/Q4862390","display_name":"Brain ischemia","level":3,"score":0.4162610173225403},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3670092821121216},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36671730875968933},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3061116337776184},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.29216301441192627},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.19715702533721924},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.16024169325828552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1143178939819336},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.09525856375694275},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06489819288253784},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-2-8178-0761-4_20","doi":"https://doi.org/10.1007/978-2-8178-0761-4_20","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-2-8178-0761-4_20","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Basis for Microcirculatory Disorders","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.6299999952316284,"display_name":"Life below water","id":"https://metadata.un.org/sdg/14"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":236,"referenced_works":["https://openalex.org/W37127282","https://openalex.org/W62132816","https://openalex.org/W76343339","https://openalex.org/W99758111","https://openalex.org/W103530802","https://openalex.org/W116391231","https://openalex.org/W141073813","https://openalex.org/W146497795","https://openalex.org/W192824317","https://openalex.org/W207753262","https://openalex.org/W402438237","https://openalex.org/W566333469","https://openalex.org/W584183608","https://openalex.org/W595264456","https://openalex.org/W1495433228","https://openalex.org/W1496598319","https://openalex.org/W1504054592","https://openalex.org/W1507312029","https://openalex.org/W1508621167","https://openalex.org/W1510591818","https://openalex.org/W1525482898","https://openalex.org/W1532538322","https://openalex.org/W1539458412","https://openalex.org/W1567947832","https://openalex.org/W1587963927","https://openalex.org/W1629553314","https://openalex.org/W1636889788","https://openalex.org/W1780368148","https://openalex.org/W1794250506","https://openalex.org/W1823315977","https://openalex.org/W1870489094","https://openalex.org/W1922537076","https://openalex.org/W1925673941","https://openalex.org/W1950659556","https://openalex.org/W1960952181","https://openalex.org/W1964023189","https://openalex.org/W1964894126","https://openalex.org/W1965335274","https://openalex.org/W1965655136","https://openalex.org/W1966875441","https://openalex.org/W1968734559","https://openalex.org/W1971020940","https://openalex.org/W1971153516","https://openalex.org/W1971159096","https://openalex.org/W1972187733","https://openalex.org/W1973982955","https://openalex.org/W1976425448","https://openalex.org/W1978166151","https://openalex.org/W1979090235","https://openalex.org/W1980369396","https://openalex.org/W1980406902","https://openalex.org/W1980577220","https://openalex.org/W1980793025","https://openalex.org/W1981505979","https://openalex.org/W1983998528","https://openalex.org/W1985361423","https://openalex.org/W1986004576","https://openalex.org/W1986744692","https://openalex.org/W1986948142","https://openalex.org/W1987197699","https://openalex.org/W1989171577","https://openalex.org/W1990711278","https://openalex.org/W1991282949","https://openalex.org/W1991309938","https://openalex.org/W1992145204","https://openalex.org/W1993119301","https://openalex.org/W1995599438","https://openalex.org/W1996871180","https://openalex.org/W1997255414","https://openalex.org/W1997338548","https://openalex.org/W1998200062","https://openalex.org/W1998457745","https://openalex.org/W1998916449","https://openalex.org/W1999292509","https://openalex.org/W1999388090","https://openalex.org/W2000842099","https://openalex.org/W2001751662","https://openalex.org/W2002067726","https://openalex.org/W2003756816","https://openalex.org/W2005770414","https://openalex.org/W2007063402","https://openalex.org/W2007281897","https://openalex.org/W2007618240","https://openalex.org/W2010057452","https://openalex.org/W2011248088","https://openalex.org/W2015085032","https://openalex.org/W2015553144","https://openalex.org/W2018022526","https://openalex.org/W2018952643","https://openalex.org/W2019889454","https://openalex.org/W2020138738","https://openalex.org/W2020303700","https://openalex.org/W2021391968","https://openalex.org/W2022378197","https://openalex.org/W2023568073","https://openalex.org/W2023943992","https://openalex.org/W2024476573","https://openalex.org/W2024515551","https://openalex.org/W2025995333","https://openalex.org/W2026227267","https://openalex.org/W2028840842","https://openalex.org/W2032941828","https://openalex.org/W2033749736","https://openalex.org/W2033844247","https://openalex.org/W2034882426","https://openalex.org/W2035750459","https://openalex.org/W2040671393","https://openalex.org/W2040957577","https://openalex.org/W2041310039","https://openalex.org/W2043183468","https://openalex.org/W2043234921","https://openalex.org/W2046335509","https://openalex.org/W2046919629","https://openalex.org/W2048202821","https://openalex.org/W2049777870","https://openalex.org/W2050506940","https://openalex.org/W2052523166","https://openalex.org/W2054234083","https://openalex.org/W2054482783","https://openalex.org/W2055370959","https://openalex.org/W2056765412","https://openalex.org/W2057434326","https://openalex.org/W2059017997","https://openalex.org/W2059217502","https://openalex.org/W2059407857","https://openalex.org/W2059529904","https://openalex.org/W2059648389","https://openalex.org/W2059708499","https://openalex.org/W2061707140","https://openalex.org/W2062232008","https://openalex.org/W2063094517","https://openalex.org/W2063504330","https://openalex.org/W2064143875","https://openalex.org/W2064183906","https://openalex.org/W2067436359","https://openalex.org/W2068210940","https://openalex.org/W2069132198","https://openalex.org/W2070543132","https://openalex.org/W2070985571","https://openalex.org/W2072434750","https://openalex.org/W2072834009","https://openalex.org/W2072870301","https://openalex.org/W2074261197","https://openalex.org/W2076634690","https://openalex.org/W2076895542","https://openalex.org/W2078640332","https://openalex.org/W2079413727","https://openalex.org/W2079846047","https://openalex.org/W2080217156","https://openalex.org/W2082392406","https://openalex.org/W2083847626","https://openalex.org/W2084595515","https://openalex.org/W2086414747","https://openalex.org/W2086504482","https://openalex.org/W2087666006","https://openalex.org/W2088286474","https://openalex.org/W2091175885","https://openalex.org/W2091911439","https://openalex.org/W2092311466","https://openalex.org/W2092494622","https://openalex.org/W2094164804","https://openalex.org/W2094217870","https://openalex.org/W2100775241","https://openalex.org/W2100994529","https://openalex.org/W2104371820","https://openalex.org/W2105054347","https://openalex.org/W2107269020","https://openalex.org/W2111471304","https://openalex.org/W2112505121","https://openalex.org/W2117775170","https://openalex.org/W2118738743","https://openalex.org/W2121305414","https://openalex.org/W2122571743","https://openalex.org/W2123894485","https://openalex.org/W2124919802","https://openalex.org/W2125776388","https://openalex.org/W2126394436","https://openalex.org/W2139112966","https://openalex.org/W2139989361","https://openalex.org/W2142786915","https://openalex.org/W2142844897","https://openalex.org/W2143276205","https://openalex.org/W2148050684","https://openalex.org/W2155215582","https://openalex.org/W2155556416","https://openalex.org/W2157281786","https://openalex.org/W2157816491","https://openalex.org/W2159154575","https://openalex.org/W2161272496","https://openalex.org/W2161842595","https://openalex.org/W2164575165","https://openalex.org/W2166683087","https://openalex.org/W2167915117","https://openalex.org/W2181566246","https://openalex.org/W2257350329","https://openalex.org/W2292308933","https://openalex.org/W2292619439","https://openalex.org/W2299028436","https://openalex.org/W2310945810","https://openalex.org/W2314731888","https://openalex.org/W2316873978","https://openalex.org/W2332198986","https://openalex.org/W2336770370","https://openalex.org/W2347244514","https://openalex.org/W2395098672","https://openalex.org/W2402226646","https://openalex.org/W2403962918","https://openalex.org/W2404783726","https://openalex.org/W2407284690","https://openalex.org/W2409316657","https://openalex.org/W2411049229","https://openalex.org/W2412058136","https://openalex.org/W2412285775","https://openalex.org/W2413279894","https://openalex.org/W2413612989","https://openalex.org/W2414380852","https://openalex.org/W2415984791","https://openalex.org/W2417749014","https://openalex.org/W2418333827","https://openalex.org/W2419112847","https://openalex.org/W2429485193","https://openalex.org/W2474100939","https://openalex.org/W2483220336","https://openalex.org/W2518673658","https://openalex.org/W2790725995","https://openalex.org/W2970173479","https://openalex.org/W3023564596","https://openalex.org/W3128209757","https://openalex.org/W3146048780","https://openalex.org/W3152410314","https://openalex.org/W3152461070","https://openalex.org/W4232143967","https://openalex.org/W4235337303","https://openalex.org/W4246999129","https://openalex.org/W4300196626","https://openalex.org/W6604722133"],"related_works":["https://openalex.org/W2492891429","https://openalex.org/W2489349062","https://openalex.org/W1518778114","https://openalex.org/W2035569448","https://openalex.org/W4239518045","https://openalex.org/W2091911439","https://openalex.org/W111651625","https://openalex.org/W148402662","https://openalex.org/W2149855681","https://openalex.org/W2158069943"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
