{"id":"https://openalex.org/W331740097","doi":"https://doi.org/10.1182/blood.v89.1.72","title":"Transendothelial Migration of CD34+ and Mature Hematopoietic Cells: An In Vitro Study Using a Human Bone Marrow Endothelial Cell Line","display_name":"Transendothelial Migration of CD34+ and Mature Hematopoietic Cells: An In Vitro Study Using a Human Bone Marrow Endothelial Cell Line","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W331740097","doi":"https://doi.org/10.1182/blood.v89.1.72","mag":"331740097","pmid":"https://pubmed.ncbi.nlm.nih.gov/8978279"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v89.1.72","doi":"https://doi.org/10.1182/blood.v89.1.72","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v89.1.72","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021533208","display_name":"Robert M\u00f6hle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Mo\u0308hle","raw_affiliation_strings":["From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I4405272987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110863459","display_name":"Malcolm A.S. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malcolm A.S. Moore","raw_affiliation_strings":["From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I4405272987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058411129","display_name":"Ralph L. Nachman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralph L. Nachman","raw_affiliation_strings":["From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I4405272987"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090799132","display_name":"Shahin Rafii","orcid":"https://orcid.org/0000-0001-5605-1067","observed_orcids":["https://orcid.org/0000-0001-5605-1067"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahin Rafii","raw_affiliation_strings":["From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Laboratory of Developmental Hematopoiesis, Memorial Sloan-Kettering Cancer Center, New York; and the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"the Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I4405272987"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":7.0409,"has_fulltext":false,"cited_by_count":121,"citation_normalized_percentile":{"value":0.97768924,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"89","issue":"1","first_page":"72","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transendothelial-migration","display_name":"transendothelial migration","score":0.9399999976158142},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.925000011920929},{"id":"https://openalex.org/keywords/cd34-cells","display_name":"CD34+ cells","score":0.9810000061988831},{"id":"https://openalex.org/keywords/bone-marrow-endothelial-cells","display_name":"bone marrow endothelial cells","score":0.9789999723434448},{"id":"https://openalex.org/keywords/lfa-1","display_name":"LFA-1","score":0.7549999952316284},{"id":"https://openalex.org/keywords/l-selectin","display_name":"L-selectin","score":0.8410000205039978},{"id":"https://openalex.org/keywords/vla-4","display_name":"VLA-4","score":0.9340000152587891},{"id":"https://openalex.org/keywords/cd38","display_name":"CD38","score":0.7409999966621399},{"id":"https://openalex.org/keywords/erythroid-progenitors","display_name":"erythroid progenitor cells","score":0.9520000219345093},{"id":"https://openalex.org/keywords/granulocyte-colony-stimulating-factor","display_name":"granulocyte colony-stimulating factor","score":0.7950000166893005},{"id":"https://openalex.org/keywords/plating-efficiency","display_name":"plating efficiency","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.7746033668518066},{"id":"https://openalex.org/C159912055","wikidata":"https://www.wikidata.org/wiki/Q14885119","display_name":"CD38","level":4,"score":0.7236284613609314},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6984508037567139},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6802217960357666},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6310046911239624},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6091111898422241},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5002789497375488},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.47092360258102417},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.45931413769721985},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.43572917580604553},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3759557008743286},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3647294044494629},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3425644636154175},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.26254135370254517},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07660016417503357},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002461","descriptor_name":"Cell Line, Transformed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004727","descriptor_name":"Endothelium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018952","descriptor_name":"Antigens, CD34","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood.v89.1.72","doi":"https://doi.org/10.1182/blood.v89.1.72","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v89.1.72","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"doi:10.1182/blood.v89.1.72.72_72_80","doi":"https://doi.org/10.1182/blood.v89.1.72.72_72_80","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v89.1.72.72_72_80","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:8978279","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8978279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4312958506","display_name":"REGULATION OF THROMBOPOIESIS BY BONE MARROW ENDOTHELIUM","funder_award_id":"K08HL002926","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W74020332","https://openalex.org/W186752733","https://openalex.org/W192939105","https://openalex.org/W214380766","https://openalex.org/W331893476","https://openalex.org/W1485881176","https://openalex.org/W1538762819","https://openalex.org/W1591912379","https://openalex.org/W1627242688","https://openalex.org/W1876415395","https://openalex.org/W1907330148","https://openalex.org/W1932316892","https://openalex.org/W1966286149","https://openalex.org/W1971920241","https://openalex.org/W2006018450","https://openalex.org/W2013895496","https://openalex.org/W2021889129","https://openalex.org/W2025572360","https://openalex.org/W2032371793","https://openalex.org/W2038316393","https://openalex.org/W2061285112","https://openalex.org/W2080780289","https://openalex.org/W2128338218","https://openalex.org/W2131183827","https://openalex.org/W2150595969","https://openalex.org/W2230155133","https://openalex.org/W2332032575","https://openalex.org/W2397162000","https://openalex.org/W2405572490","https://openalex.org/W2411209420","https://openalex.org/W2416125197","https://openalex.org/W2416198997","https://openalex.org/W2438426466","https://openalex.org/W6689536554"],"related_works":["https://openalex.org/W70651026","https://openalex.org/W7101002809","https://openalex.org/W2370873043","https://openalex.org/W1521877792","https://openalex.org/W2061116995","https://openalex.org/W2169083662","https://openalex.org/W2030728982","https://openalex.org/W2142210925","https://openalex.org/W2066059341","https://openalex.org/W1611448597"],"abstract_inverted_index":{"To":[0],"study":[1,346],"the":[2,11,96,100,104,112,120,128,156,161,179,216,219,275,280,284,298,303,323],"role":[3],"of":[4,13,24,27,41,51,103,110,114,127,140,160,182,218,253,274,283,300,332,353,364],"bone":[5],"marrow":[6],"endothelial":[7],"cells":[8,30,92,116,130,135,146,164,184,194,208,241,255,278,301,329,355],"(BMEC)":[9],"in":[10,21,64,80,99,119,215,279,288,302,322,349],"regulation":[12],"hematopoietic":[14,28,333,337,366],"cell":[15,45,360],"trafficking,":[16],"we":[17,37],"have":[18,38],"designed":[19],"an":[20],"vitro":[22],"model":[23,341],"transendothelial":[25],"migration":[26],"progenitor":[29,129,153,359],"and":[31,57,78,147,202,227,265,290,294,313,318,335,351,362],"their":[32],"progeny.":[33],"For":[34],"these":[35],"studies,":[36],"taken":[39],"advantage":[40],"a":[42,137],"human":[43],"BMEC-derived":[44],"line":[46],"(BMEC-1),":[47],"which":[48],"proliferates":[49],"independent":[50],"growth":[52],"factors,":[53],"is":[54],"contact":[55],"inhibited,":[56],"expresses":[58],"adhesion":[59],"molecules":[60],"similar":[61],"to":[62,70,95,261,345],"BMEC":[63],"vivo.":[65],"BMEC-1":[66,97,328],"monolayers":[67],"were":[68,93,320],"grown":[69],"confluency":[71],"on":[72,238],"3":[73],"microns":[74],"microporous":[75],"membrane":[76],"inserts":[77,286],"placed":[79],"6-well":[81,105],"tissue":[82],"culture":[83],"plates.":[84],"Granulocytecolony":[85],"stimulating":[86],"factor":[87],"(G-CSF)-mobilized":[88],"peripheral":[89,357],"blood":[90,358],"CD34+":[91,115,145,163,207,240,277,354],"added":[94],"monolayer":[98],"upper":[101,121,281,304],"chamber":[102,282,305],"plate.":[106],"After":[107],"24":[108],"hours":[109],"coincubation,":[111],"majority":[113,299],"remained":[117],"nonadherent":[118],"chamber,":[122],"while":[123,263],"1.6":[124],"+/-":[125,171,175,196,200,210],"0.3%":[126,199],"had":[131,247,268],"transmigrated.":[132],"Transmigrated":[133],"CD34":[134],"expressed":[136],"higher":[138,169],"level":[139],"CD38":[141],"compared":[142,191,204],"with":[143,192,205],"nonmigrating":[144,193],"may":[148,342],"therefore":[149],"represent":[150],"predominantly":[151],"committed":[152],"cells.":[154,296,338,367],"Accordingly,":[155],"total":[157],"plating":[158,180],"efficiency":[159,181],"transmigrated":[162,183,239,254],"for":[165,185],"lineage-committed":[166],"progenitors":[167,187,334],"was":[168,188,234,242,256],"(14.0":[170],"0.1":[172],"v":[173,198],"7.8%":[174],"1.5%).":[176],"In":[177,326],"particular,":[178],"erythroid":[186],"27-fold":[189],"greater":[190],"(8.0%":[195],"0.8%":[197],"0.1%)":[201],"5.5-fold":[203],"unprocessed":[206],"(2.2%":[209],"0.4%).":[211],"While":[212,297],"no":[213,269],"difference":[214],"expression":[217,237],"beta":[220,228],"1-integrin":[221],"very":[222],"late":[223],"activation":[224],"antigen":[225,232],"(VLA)-4":[226],"2-integrin":[229],"lymphocyte":[230],"function-associated":[231],"(LFA)-1":[233],"found,":[235],"L-selectin":[236,264],"lost,":[243],"suggesting":[244],"that":[245],"shedding":[246],"occurred":[248],"during":[249,356],"migration.":[250],"The":[251],"number":[252],"reduced":[257],"by":[258],"blocking":[259],"antibodies":[260,267],"LFA-1,":[262],"VLA-4":[266],"inhibitory":[270],"effect.":[271],"Continuous":[272],"coculture":[273],"remaining":[276],"transwell":[285],"resulted":[287],"proliferation":[289],"differentiation":[291],"into":[292],"myeloid":[293,308],"megakaryocytic":[295],"comprised":[306],"proliferating":[307],"precursors":[309],"such":[310],"as":[311],"promyelocytes":[312],"myelocytes,":[314],"only":[315],"mature":[316,336,365],"monocytes":[317],"granulocytes":[319],"detected":[321],"lower":[324],"chamber.":[325],"conclusion,":[327],"support":[330],"transmigration":[331],"Therefore,":[339],"this":[340],"be":[343],"used":[344],"mechanisms":[347],"involved":[348],"mobilization":[350],"homing":[352],"transplantation":[361],"trafficking":[363]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}