{"id":"https://openalex.org/W33156491","doi":null,"title":"\u30de\u30a6\u30b9\u306eLPS\u8a98\u767a\u9ed2\u8cea\u30c9\u30d1\u30df\u30f3\u795e\u7d4c\u7d30\u80de\u969c\u5bb3\u306b\u304a\u3051\u308bcaspase-11\u306e\u95a2\u4e0e(\u5e73\u621015\u5e74\u5ea6\u9806\u5929\u5802\u5927\u5b66\u8001\u4eba\u6027\u75be\u60a3\u75c5\u614b\u30fb\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u767a\u8868\u4f1a\u6284\u9332)","display_name":"\u30de\u30a6\u30b9\u306eLPS\u8a98\u767a\u9ed2\u8cea\u30c9\u30d1\u30df\u30f3\u795e\u7d4c\u7d30\u80de\u969c\u5bb3\u306b\u304a\u3051\u308bcaspase-11\u306e\u95a2\u4e0e(\u5e73\u621015\u5e74\u5ea6\u9806\u5929\u5802\u5927\u5b66\u8001\u4eba\u6027\u75be\u60a3\u75c5\u614b\u30fb\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u767a\u8868\u4f1a\u6284\u9332)","publication_year":2004,"publication_date":"2004-12-22","ids":{"openalex":"https://openalex.org/W33156491","mag":"33156491"},"language":"ja","primary_location":{"id":"mag:33156491","doi":null,"is_oa":true,"landing_page_url":"http://ci.nii.ac.jp/naid/110004299108","pdf_url":null,"source":{"id":"https://openalex.org/S4210214158","display_name":"Juntend\u014d Igaku/Juntendo igaku","issn_l":"0022-6769","issn":["0022-6769","2187-9737","2188-2126","2188-2134","2759-7504"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u9806\u5929\u5802\u533b\u5b66","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://ci.nii.ac.jp/naid/110004299108","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054105167","display_name":"\u88d5\u5e78 \u65b0\u4e95","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u88d5\u5e78 \u65b0\u4e95","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012124243","display_name":"\u79c0\u6a39 \u671b\u6708","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u79c0\u6a39 \u671b\u6708","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091301441","display_name":"\u7f8e\u90a6 \u6c34\u91ce","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u7f8e\u90a6 \u6c34\u91ce","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5052911006","display_name":"\u6b63\u5e78 \u4e09\u6d66","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u6b63\u5e78 \u4e09\u6d66","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00207632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"50","issue":"4","first_page":"420","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.7202000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.7202000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.16369999945163727,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.09440000355243683,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caspase-11","display_name":"caspase-11","score":0.972000002861023},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.949999988079071},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.6850000023841858},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.7210000157356262},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.5609999895095825},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41537562012672424},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.326540470123291}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:33156491","doi":null,"is_oa":true,"landing_page_url":"http://ci.nii.ac.jp/naid/110004299108","pdf_url":null,"source":{"id":"https://openalex.org/S4210214158","display_name":"Juntend\u014d Igaku/Juntendo igaku","issn_l":"0022-6769","issn":["0022-6769","2187-9737","2188-2126","2188-2134","2759-7504"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u9806\u5929\u5802\u533b\u5b66","raw_type":null}],"best_oa_location":{"id":"mag:33156491","doi":null,"is_oa":true,"landing_page_url":"http://ci.nii.ac.jp/naid/110004299108","pdf_url":null,"source":{"id":"https://openalex.org/S4210214158","display_name":"Juntend\u014d Igaku/Juntendo igaku","issn_l":"0022-6769","issn":["0022-6769","2187-9737","2188-2126","2188-2134","2759-7504"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u9806\u5929\u5802\u533b\u5b66","raw_type":null},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2395500549","display_name":"\u5bf9\u6c28\u57fa\u6c34\u6768\u9178\u94a0\u5bf9\u9530\u81f4\u795e\u7ecf\u708e\u75c7\u7684\u5e72\u9884\u673a\u5236","funder_award_id":"81460505","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6259163749","display_name":null,"funder_award_id":"81973094","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G9000891646","display_name":"Mechanisms of Manganese Neurotoxicity","funder_award_id":"R01ES010563","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W2004714156","https://openalex.org/W2592077895","https://openalex.org/W2009132341","https://openalex.org/W2115316180","https://openalex.org/W2910109864","https://openalex.org/W2674021548","https://openalex.org/W2604440807","https://openalex.org/W2087182644","https://openalex.org/W1962824084","https://openalex.org/W2527645962","https://openalex.org/W2617293585","https://openalex.org/W2611861607","https://openalex.org/W2000397914","https://openalex.org/W2909458901","https://openalex.org/W2789458441","https://openalex.org/W2590953783","https://openalex.org/W2124018389","https://openalex.org/W1971379772","https://openalex.org/W2076056524","https://openalex.org/W2704730568","https://openalex.org/W1203509696","https://openalex.org/W2477239117","https://openalex.org/W2942474702","https://openalex.org/W2014721161","https://openalex.org/W2986323652","https://openalex.org/W2158587319","https://openalex.org/W2914464117","https://openalex.org/W3040475880","https://openalex.org/W2069893872","https://openalex.org/W2019201618","https://openalex.org/W2129720180","https://openalex.org/W2099784156","https://openalex.org/W2118918019","https://openalex.org/W1986611577","https://openalex.org/W2928364879","https://openalex.org/W2768081880","https://openalex.org/W2032827308","https://openalex.org/W2914743334","https://openalex.org/W2021194864","https://openalex.org/W2941630117","https://openalex.org/W2750718695","https://openalex.org/W2789900283","https://openalex.org/W2073225954","https://openalex.org/W2945862226","https://openalex.org/W2791444686","https://openalex.org/W582182564","https://openalex.org/W4211217520"],"related_works":["https://openalex.org/W262137772","https://openalex.org/W2302375065","https://openalex.org/W654170181","https://openalex.org/W255730374","https://openalex.org/W620300748","https://openalex.org/W2469470316","https://openalex.org/W7208461139","https://openalex.org/W2999168763","https://openalex.org/W2751426023","https://openalex.org/W3179008562"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}