{"id":"https://openalex.org/W331151710","doi":null,"title":"Inflammation in various stages of coronary heart disease","display_name":"Inflammation in various stages of coronary heart disease","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W331151710","mag":"331151710"},"language":"en","primary_location":{"id":"pmh:oai:www.duo.uio.no:10852/28089","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10852/28089","pdf_url":null,"source":{"id":"https://openalex.org/S4306401716","display_name":"Duo Research Archive (University of Oslo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184942183","host_organization_name":"University of Oslo","host_organization_lineage":["https://openalex.org/I184942183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006868417","display_name":"Svein Solheim","orcid":"https://orcid.org/0000-0003-3321-6572","observed_orcids":["https://orcid.org/0000-0003-3321-6572"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Svein Solheim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3321-6572","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5006868417"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.16349999606609344,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.0746999979019165,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.9259999990463257},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9610000252723694},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.921999990940094},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9100000262260437},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.9190000295639038},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.9279999732971191},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mcp-1","display_name":"MCP-1","score":0.9869999885559082},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9070000052452087},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9779999852180481},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9580000042915344},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.9319999814033508},{"id":"https://openalex.org/keywords/intracoronary-injection","display_name":"intracoronary injection","score":0.6299999952316284},{"id":"https://openalex.org/keywords/autologous-bone-marrow-cells","display_name":"autologous bone marrow cells","score":0.9739999771118164},{"id":"https://openalex.org/keywords/left-ventricular-function","display_name":"left ventricular function","score":0.8510000109672546},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.8659999966621399},{"id":"https://openalex.org/keywords/systemic-inflammatory-response","display_name":"systemic inflammatory response","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6444598436355591},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5576105117797852},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48513922095298767},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4739501476287842},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.46641644835472107},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45940959453582764}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:www.duo.uio.no:10852/28089","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10852/28089","pdf_url":null,"source":{"id":"https://openalex.org/S4306401716","display_name":"Duo Research Archive (University of Oslo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184942183","host_organization_name":"University of Oslo","host_organization_lineage":["https://openalex.org/I184942183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},{"id":"mag:331151710","doi":null,"is_oa":false,"landing_page_url":"https://www.duo.uio.no/bitstream/10852/28089/1/569_Solheim_DUO.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":195,"referenced_works":["https://openalex.org/W9351151","https://openalex.org/W63336923","https://openalex.org/W82493482","https://openalex.org/W122329515","https://openalex.org/W145436955","https://openalex.org/W204748008","https://openalex.org/W272477769","https://openalex.org/W645716187","https://openalex.org/W1483584036","https://openalex.org/W1486677432","https://openalex.org/W1516434930","https://openalex.org/W1545898053","https://openalex.org/W1553345686","https://openalex.org/W1561516029","https://openalex.org/W1578648368","https://openalex.org/W1593794388","https://openalex.org/W1631250427","https://openalex.org/W1963936317","https://openalex.org/W1966000886","https://openalex.org/W1966129325","https://openalex.org/W1966161569","https://openalex.org/W1966296687","https://openalex.org/W1967128858","https://openalex.org/W1971456874","https://openalex.org/W1973484869","https://openalex.org/W1974009242","https://openalex.org/W1974718993","https://openalex.org/W1979608640","https://openalex.org/W1980087271","https://openalex.org/W1981522023","https://openalex.org/W1981851376","https://openalex.org/W1983893679","https://openalex.org/W1985230293","https://openalex.org/W1989780776","https://openalex.org/W1989880720","https://openalex.org/W1990617236","https://openalex.org/W1990996704","https://openalex.org/W1991403773","https://openalex.org/W1991998151","https://openalex.org/W1992152105","https://openalex.org/W1994527422","https://openalex.org/W1994994439","https://openalex.org/W1995702870","https://openalex.org/W1996540389","https://openalex.org/W1996866382","https://openalex.org/W1998953697","https://openalex.org/W2000889091","https://openalex.org/W2001044397","https://openalex.org/W2003379945","https://openalex.org/W2006353464","https://openalex.org/W2006465989","https://openalex.org/W2006968633","https://openalex.org/W2007716988","https://openalex.org/W2009978724","https://openalex.org/W2010237936","https://openalex.org/W2010431766","https://openalex.org/W2011192430","https://openalex.org/W2013521697","https://openalex.org/W2013595930","https://openalex.org/W2014950417","https://openalex.org/W2016367473","https://openalex.org/W2016986936","https://openalex.org/W2017871510","https://openalex.org/W2019472123","https://openalex.org/W2021314070","https://openalex.org/W2022185139","https://openalex.org/W2023417206","https://openalex.org/W2026236910","https://openalex.org/W2026473142","https://openalex.org/W2027208842","https://openalex.org/W2027415701","https://openalex.org/W2028128714","https://openalex.org/W2032207767","https://openalex.org/W2032485049","https://openalex.org/W2032901102","https://openalex.org/W2033855639","https://openalex.org/W2035720710","https://openalex.org/W2038613403","https://openalex.org/W2039420330","https://openalex.org/W2039552376","https://openalex.org/W2039601697","https://openalex.org/W2041460518","https://openalex.org/W2043677945","https://openalex.org/W2046051565","https://openalex.org/W2055083588","https://openalex.org/W2055752072","https://openalex.org/W2056539295","https://openalex.org/W2057645565","https://openalex.org/W2057905142","https://openalex.org/W2058591384","https://openalex.org/W2058610272","https://openalex.org/W2059279349","https://openalex.org/W2060480041","https://openalex.org/W2061812498","https://openalex.org/W2063562293","https://openalex.org/W2066963386","https://openalex.org/W2067504868","https://openalex.org/W2067895655","https://openalex.org/W2068328960","https://openalex.org/W2069681479","https://openalex.org/W2070396041","https://openalex.org/W2070446231","https://openalex.org/W2073751205","https://openalex.org/W2077075851","https://openalex.org/W2078617119","https://openalex.org/W2079721567","https://openalex.org/W2081662576","https://openalex.org/W2081810637","https://openalex.org/W2083601587","https://openalex.org/W2084052630","https://openalex.org/W2084109090","https://openalex.org/W2084676615","https://openalex.org/W2084744450","https://openalex.org/W2087750804","https://openalex.org/W2088499548","https://openalex.org/W2089272736","https://openalex.org/W2089892676","https://openalex.org/W2089941399","https://openalex.org/W2092043066","https://openalex.org/W2092523982","https://openalex.org/W2093664978","https://openalex.org/W2094941678","https://openalex.org/W2095282566","https://openalex.org/W2096210315","https://openalex.org/W2096280264","https://openalex.org/W2096917705","https://openalex.org/W2097796010","https://openalex.org/W2098910999","https://openalex.org/W2100308572","https://openalex.org/W2104898886","https://openalex.org/W2106343349","https://openalex.org/W2109212247","https://openalex.org/W2110248987","https://openalex.org/W2111486034","https://openalex.org/W2112360098","https://openalex.org/W2112568641","https://openalex.org/W2114675295","https://openalex.org/W2114722474","https://openalex.org/W2115163080","https://openalex.org/W2115268091","https://openalex.org/W2117770728","https://openalex.org/W2118402202","https://openalex.org/W2120386620","https://openalex.org/W2121308654","https://openalex.org/W2121504382","https://openalex.org/W2122146058","https://openalex.org/W2125155374","https://openalex.org/W2125635123","https://openalex.org/W2125751345","https://openalex.org/W2127191881","https://openalex.org/W2129785124","https://openalex.org/W2133449490","https://openalex.org/W2135392289","https://openalex.org/W2135479614","https://openalex.org/W2135568455","https://openalex.org/W2138135866","https://openalex.org/W2144473676","https://openalex.org/W2147340189","https://openalex.org/W2147454356","https://openalex.org/W2148597937","https://openalex.org/W2151722542","https://openalex.org/W2152658552","https://openalex.org/W2155191102","https://openalex.org/W2156722540","https://openalex.org/W2156744146","https://openalex.org/W2157475544","https://openalex.org/W2157653707","https://openalex.org/W2159087408","https://openalex.org/W2159718273","https://openalex.org/W2160094856","https://openalex.org/W2161905914","https://openalex.org/W2162106476","https://openalex.org/W2162637702","https://openalex.org/W2162886638","https://openalex.org/W2162976988","https://openalex.org/W2163625494","https://openalex.org/W2164506013","https://openalex.org/W2164807534","https://openalex.org/W2165911176","https://openalex.org/W2167591919","https://openalex.org/W2167595513","https://openalex.org/W2170062988","https://openalex.org/W2170685923","https://openalex.org/W2315575691","https://openalex.org/W2316243284","https://openalex.org/W2316376271","https://openalex.org/W2317184793","https://openalex.org/W2322095705","https://openalex.org/W2324841714","https://openalex.org/W2326754541","https://openalex.org/W2397125770","https://openalex.org/W2411382828","https://openalex.org/W2417993973","https://openalex.org/W2615584519","https://openalex.org/W2620550732"],"related_works":["https://openalex.org/W2156172294","https://openalex.org/W7099932068","https://openalex.org/W2567151956","https://openalex.org/W2000783008","https://openalex.org/W2041258831","https://openalex.org/W2279093836","https://openalex.org/W2111554117","https://openalex.org/W1999254107","https://openalex.org/W2236970829","https://openalex.org/W2354761007"],"abstract_inverted_index":{"Inflammation":[0],"plays":[1],"a":[2,36,169,218,269],"key":[3],"role":[4],"in":[5,39,51,82,91,117,147,174,205,208,244,283],"atherosclerosis":[6],"and":[7,12,61,139,152,179,268],"acute":[8,109,161,258],"myocardial":[9,164,215],"infarction":[10,165,216],"(AMI),":[11],"circulating":[13,175],"levels":[14,87,149,176,207],"of":[15,25,43,56,69,72,88,120,150,177,184,252],"inflammatory":[16,220,225,272],"substances":[17],"may":[18,265,278],"reflect":[19],"the":[20,29,44,67,118,148,224,229,284],"ongoing":[21],"process.":[22],"Lately,":[23],"transplantation":[24],"stem":[26,285],"cells":[27,76],"from":[28],"bone":[30,74],"marrow":[31,75],"has":[32],"been":[33],"suggested":[34],"as":[35,181,183],"treatment":[37,64,133],"option":[38],"AMI.":[40,83],"\\nThe":[41],"aim":[42],"present":[45],"thesis":[46],"was":[47],"to":[48,100,104,187],"examine":[49],"inflammation":[50],"patients":[52,92,127,159,190,209,245],"with":[53,94,128,134,160,167,191,210,246,249],"various":[54,63],"stages":[55],"coronary":[57],"heart":[58],"disease":[59],"(CHD)":[60],"during":[62],"modalities,":[65],"including":[66],"effects":[68,233],"intracoronary":[70,250],"injection":[71,251],"autologous":[73,253],"(mBMC)":[77],"on":[78,234],"left":[79,236],"ventricular":[80,237],"function":[81,238],"\\nWe":[84],"found":[85],"reduced":[86,271],"pro-inflammatory":[89,262],"markers":[90],"treated":[93,166,189,248,287],"aspirin":[95,135],"160":[96,136],"mg":[97,137,142],"daily":[98,138,143],"compared":[99,186],"warfarin":[101],"for":[102],"up":[103],"4":[105,124],"years":[106],"after":[107,123,239,257,274],"an":[108,203],"MI.":[110],"However,":[111],"these":[112],"findings":[113],"were":[114,242,281],"not":[115],"reflected":[116],"incidence":[119],"clinical":[121],"end-points":[122],"years.":[125],"\\nIn":[126,158],"stable":[129,192,211],"CHD":[130],"1":[131],"year":[132],"clopidogrel":[140],"75":[141],"induced":[144,202,217,227],"similar":[145],"reduction":[146],"TNF\u03b1":[151],"MCP-1,":[153],"possibly":[154],"by":[155,228],"different":[156],"mechanisms.":[157],"ST-segment":[162],"elevation":[163],"PCI":[168,197,230],"marked":[170],"short":[171],"term":[172],"increase":[173,204],"IL-6":[178,206],"CRP":[180],"well":[182],"IL-10":[185],"similarly":[188],"angina":[193,212],"pectoris":[194],"appeared.":[195],"The":[196,214],"procedure":[198],"per":[199],"se":[200],"also":[201],"pectoris.":[213],"systemic":[219],"reaction":[221],"that":[222,264,277],"overwhelmed":[223],"response":[226,263,273],"procedure.":[231],"\\nNo":[232],"global":[235],"6":[240,255],"months":[241,276],"obtained":[243],"AMI":[247],"mBMC":[254],"days":[256],"PCI.":[259],"A":[260],"short-term":[261],"be":[266,279],"unfavourable,":[267],"slightly":[270],"3":[275],"beneficial,":[280],"noted":[282],"cell":[286],"patients.":[288]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}