{"id":"https://openalex.org/W33059909","doi":null,"title":"Cardiomyocyte-restricted PPAR{delta} deletion in PPAR{alpha} null mice leads to cardiac hypertrophy and heart failure","display_name":"Cardiomyocyte-restricted PPAR{delta} deletion in PPAR{alpha} null mice leads to cardiac hypertrophy and heart failure","publication_year":2008,"publication_date":"2008-03-01","ids":{"openalex":"https://openalex.org/W33059909","mag":"33059909"},"language":"en","primary_location":{"id":"mag:33059909","doi":null,"is_oa":false,"landing_page_url":"https://www.fasebj.org/cgi/content/meeting_abstract/22/1_MeetingAbstracts/613.5","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"The FASEB Journal","raw_type":null},"volume":null,"type":"conference-abstract","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100414710","display_name":"Jian Liu","orcid":"https://orcid.org/0000-0002-8969-8446","observed_orcids":["https://orcid.org/0000-0002-8969-8446"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jian Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8969-8446","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025866012","display_name":"Peiyong Wang","orcid":"https://orcid.org/0000-0001-6716-5174","observed_orcids":["https://orcid.org/0000-0001-6716-5174"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peiyong Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6716-5174","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066316498","display_name":"Lihong Cheng","orcid":"https://orcid.org/0000-0002-2522-4831","observed_orcids":["https://orcid.org/0000-0002-2522-4831"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lihong Cheng","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2522-4831","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084911428","display_name":"Lawrence A. Brako","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lawrence Brako","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5101884781","display_name":"Qinglin Yang","orcid":"https://orcid.org/0000-0002-6024-2517","observed_orcids":["https://orcid.org/0000-0002-6024-2517"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qinglin Yang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6024-2517","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ppardelta","display_name":"PPAR\u03b4","score":0.7990000247955322},{"id":"https://openalex.org/keywords/pparalpha","display_name":"PPAR\u03b1","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cardiac-hypertrophy","display_name":"cardiac hypertrophy","score":0.9850000143051147},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pparalpha-null-mice","display_name":"PPARalpha-null mice","score":0.6940000057220459},{"id":"https://openalex.org/keywords/nuclear-receptor-signaling","display_name":"nuclear receptor signaling","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C187345961","wikidata":"https://www.wikidata.org/wiki/Q419629","display_name":"Peroxisome proliferator-activated receptor","level":3,"score":0.6525264382362366},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6488375663757324},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.6217176914215088},{"id":"https://openalex.org/C203763787","wikidata":"https://www.wikidata.org/wiki/Q371029","display_name":"Null (SQL)","level":2,"score":0.5727204084396362},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49792909622192383},{"id":"https://openalex.org/C3018791406","wikidata":"https://www.wikidata.org/wiki/Q945225","display_name":"Cardiac hypertrophy","level":3,"score":0.4973311722278595},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46818721294403076},{"id":"https://openalex.org/C5072461","wikidata":"https://www.wikidata.org/wiki/Q49506","display_name":"Delta","level":2,"score":0.4372013211250305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3933615982532501},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3585421144962311},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.24283072352409363},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.23622310161590576},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.123180091381073},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.057239264249801636},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C2775944032","wikidata":"https://www.wikidata.org/wiki/Q22907659","display_name":"Patient satisfaction","level":2,"score":0.0},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:33059909","doi":null,"is_oa":false,"landing_page_url":"https://www.fasebj.org/cgi/content/meeting_abstract/22/1_MeetingAbstracts/613.5","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"The FASEB Journal","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1987379269","display_name":"Development of a Novel Statewide Learning Collaborative to Increase Lung Cancer Guideline Adherence and Improve Cancer Care Delivery","funder_award_id":"K07CA216330","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308356","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659"},{"id":"https://openalex.org/F4320308401","display_name":"American Association for Thoracic Surgery","ror":"https://ror.org/048f8az88"},{"id":"https://openalex.org/F4320311897","display_name":"Thoracic Surgery Foundation","ror":"https://ror.org/0009jge67"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3175652201","https://openalex.org/W7098639368","https://openalex.org/W2138547211","https://openalex.org/W3095603938","https://openalex.org/W4386018748","https://openalex.org/W2036444220","https://openalex.org/W2023375840","https://openalex.org/W2084025523","https://openalex.org/W6999339470","https://openalex.org/W2138906884"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}