{"id":"https://openalex.org/W330428348","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","title":"The coming of age of adoptive T-cell therapy for viral infection after stem cell transplantation.","display_name":"The coming of age of adoptive T-cell therapy for viral infection after stem cell transplantation.","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W330428348","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","mag":"330428348","pmid":"https://pubmed.ncbi.nlm.nih.gov/25992361","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402608"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4402608","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402608","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Transl Med","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402608","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103723692","display_name":"Austin John Barrett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]},{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Austin John Barrett","raw_affiliation_strings":["1 National Heart Lung and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD, USA ; 2 Children's National Health System and The George Washington University, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 National Heart Lung and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD, USA ; 2 Children's National Health System and The George Washington University, Washington, DC, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1336742384","https://openalex.org/I193531525","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006134549","display_name":"Catherine M. Bollard","orcid":"https://orcid.org/0000-0001-5140-9090","observed_orcids":["https://orcid.org/0000-0001-5140-9090"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]},{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine M Bollard","raw_affiliation_strings":["1 National Heart Lung and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD, USA ; 2 Children's National Health System and The George Washington University, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 National Heart Lung and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD, USA ; 2 Children's National Health System and The George Washington University, Washington, DC, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1336742384","https://openalex.org/I193531525","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.4033,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.92200602,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"5","first_page":"62","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.02759999968111515,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.015599999576807022,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adoptive-t-cell-therapy","display_name":"adoptive T cell therapy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/viral-infection","display_name":"viral infection","score":0.597000002861023},{"id":"https://openalex.org/keywords/allogeneic-stem-cell-transplantation","display_name":"allogeneic stem cell transplantation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/graft-versus-malignancy-effect","display_name":"graft-versus-malignancy effect","score":0.7960000038146973},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.8519999980926514},{"id":"https://openalex.org/keywords/donor-t-cells","display_name":"donor T cells","score":0.8299999833106995},{"id":"https://openalex.org/keywords/viral-reactivation","display_name":"viral reactivation","score":0.734000027179718},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9279999732971191},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.8930000066757202},{"id":"https://openalex.org/keywords/immune-reconstitution","display_name":"immune reconstitution","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.7289124727249146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6975473165512085},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6495190858840942},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5912805795669556},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5516902208328247},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5275570750236511},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5247145891189575},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.5048542618751526},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.48954543471336365},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1675942838191986},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12065061926841736},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:4402608","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402608","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Transl Med","raw_type":"Text"},{"id":"pmid:25992361","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25992361","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of translational medicine","raw_type":"Journal Article"},{"id":"mag:330428348","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25992361","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4402608","doi":"https://doi.org/10.3978/j.issn.2305-5839.2015.01.18","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402608","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Transl Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G182350674","display_name":"Novel Cord Blood-Derived Cellular Therapies","funder_award_id":"P01CA148600","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1966515668","https://openalex.org/W1973683879","https://openalex.org/W1976058260","https://openalex.org/W1979593849","https://openalex.org/W1983062149","https://openalex.org/W1992600856","https://openalex.org/W1993501579","https://openalex.org/W1993732758","https://openalex.org/W1996092614","https://openalex.org/W2001322181","https://openalex.org/W2006436161","https://openalex.org/W2006728006","https://openalex.org/W2009607549","https://openalex.org/W2011093626","https://openalex.org/W2017769703","https://openalex.org/W2019904910","https://openalex.org/W2040400654","https://openalex.org/W2063128000","https://openalex.org/W2066214953","https://openalex.org/W2066857625","https://openalex.org/W2069720281","https://openalex.org/W2072449898","https://openalex.org/W2092863936","https://openalex.org/W2098327768","https://openalex.org/W2100114137","https://openalex.org/W2143089084","https://openalex.org/W2166295153","https://openalex.org/W2413673691"],"related_works":["https://openalex.org/W1987754685","https://openalex.org/W4463774","https://openalex.org/W6987041697","https://openalex.org/W1973982915","https://openalex.org/W2585193261","https://openalex.org/W4385219064","https://openalex.org/W2003117080","https://openalex.org/W7096567326","https://openalex.org/W3097641844","https://openalex.org/W2399328737"],"abstract_inverted_index":{"The":[0],"success":[1],"or":[2],"failure":[3],"of":[4,14,25,29,44,61],"allogeneic":[5],"stem":[6],"cell":[7],"transplantation":[8],"(SCT)":[9],"in":[10,41],"curing":[11],"a":[12,19,37],"variety":[13],"hematological":[15,45],"disorders,":[16],"centers":[17],"to":[18],"large":[20],"extent":[21],"on":[22],"the":[23,26,30,59,65],"quality":[24],"immune":[27],"recovery":[28],"donor":[31,47,71],"graft.":[32,66],"As":[33,67],"well":[34],"as":[35],"exerting":[36],"graft-versus-malignancy":[38],"effect,":[39],"critical":[40],"achieving":[42],"cure":[43],"malignancies,":[46],"T":[48,72],"lymphocytes":[49,73],"confer":[50],"protective":[51],"immunity":[52],"against":[53],"resident":[54],"viruses":[55],"that":[56],"reactivate":[57],"during":[58],"period":[60],"profound":[62],"immunosuppression":[63],"following":[64],"they":[68],"engraft":[69],"alloreacting":[70],"can":[74],"cause":[75],"life-threatening":[76],"graft":[77],"versus":[78],"host":[79],"disease":[80],"(GVHD).":[81]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}