{"id":"https://openalex.org/W32802961","doi":null,"title":"Recognition and diagnosis of atypical depression.","display_name":"Recognition and diagnosis of atypical depression.","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W32802961","mag":"32802961","pmid":"https://pubmed.ncbi.nlm.nih.gov/17640153"},"language":"en","primary_location":{"id":"pmid:17640153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17640153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085107940","display_name":"Michael E. Thase","orcid":"https://orcid.org/0000-0002-6403-0861","observed_orcids":["https://orcid.org/0000-0002-6403-0861","https://orcid.org/0009-0002-3646-845X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael E Thase","raw_affiliation_strings":["Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19380, USA. thase@mail.med.upenn.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19380, USA. thase@mail.med.upenn.edu","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085107940"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":null,"apc_paid":null,"fwci":6.12,"has_fulltext":false,"cited_by_count":96,"citation_normalized_percentile":{"value":0.96373705,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"68 Suppl 8","issue":null,"first_page":"11","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atypical-depression","display_name":"atypical depression","score":1.0},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.7670000195503235},{"id":"https://openalex.org/keywords/dsm-iv-criteria","display_name":"DSM-IV diagnostic criteria","score":0.722000002861023},{"id":"https://openalex.org/keywords/mood-reactivity","display_name":"mood reactivity","score":0.7900000214576721},{"id":"https://openalex.org/keywords/monoamine-oxidase-inhibitors","display_name":"monoamine oxidase inhibitors","score":0.7910000085830688},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9929999709129333},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.8019999861717224},{"id":"https://openalex.org/keywords/panic-disorder-with-agoraphobia","display_name":"panic disorder with agoraphobia","score":0.8159999847412109},{"id":"https://openalex.org/keywords/melancholia","display_name":"melancholia","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C2776571617","wikidata":"https://www.wikidata.org/wiki/Q2657784","display_name":"Atypical depression","level":3,"score":0.8597465753555298},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6713851690292358},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.6218152046203613},{"id":"https://openalex.org/C72852651","wikidata":"https://www.wikidata.org/wiki/Q845300","display_name":"Nosology","level":2,"score":0.5881514549255371},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5881043672561646},{"id":"https://openalex.org/C2778678127","wikidata":"https://www.wikidata.org/wiki/Q174589","display_name":"Agoraphobia","level":4,"score":0.4736132323741913},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.46142202615737915},{"id":"https://openalex.org/C2781044885","wikidata":"https://www.wikidata.org/wiki/Q13512178","display_name":"Melancholic depression","level":4,"score":0.43941327929496765},{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.4310368299484253},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.41735750436782837},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4171203076839447},{"id":"https://openalex.org/C2780820931","wikidata":"https://www.wikidata.org/wiki/Q29299","display_name":"Irritability","level":3,"score":0.4163474440574646},{"id":"https://openalex.org/C2781210005","wikidata":"https://www.wikidata.org/wiki/Q6738337","display_name":"Major depressive episode","level":3,"score":0.4104193449020386},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.3978911340236664},{"id":"https://openalex.org/C2780783166","wikidata":"https://www.wikidata.org/wiki/Q192077","display_name":"Melancholia","level":3,"score":0.380035400390625},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008996","descriptor_name":"Monoamine Oxidase Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:17640153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17640153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},{"id":"mag:32802961","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17640153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W2466786818","https://openalex.org/W2905946891"],"related_works":["https://openalex.org/W1963689439","https://openalex.org/W1707183381","https://openalex.org/W1999422364","https://openalex.org/W7214107572","https://openalex.org/W2073365476","https://openalex.org/W7097617594","https://openalex.org/W1966511169","https://openalex.org/W2013634548","https://openalex.org/W1997900538","https://openalex.org/W2080825472"],"abstract_inverted_index":{"The":[0,78,145,178],"term":[1],"atypical":[2,32,65,84,103,110,161,173,182,214,225],"depression":[3,85,111,174,183,226],"dates":[4],"to":[5,14,25,49,53,90,94],"the":[6,62,74,82,153,157,167,181,191,199,216,221,228],"first":[7],"wave":[8],"of":[9,58,81,96,135,147,156,170,180,206,220,224,230],"reports":[10],"describing":[11],"differential":[12,186],"response":[13],"monoamine":[15],"oxidase":[16],"inhibitors":[17],"(MAOIs)":[18],"and":[19,44,60,120,132,140,218],"tricyclic":[20],"antidepressants":[21,197],"(TCAs).":[22],"In":[23],"contrast":[24],"more":[26,51,129],"TCA-responsive":[27],"depressions,":[28],"patients":[29,97,171],"with":[30,98,137,143,165,172],"so-called":[31],"symptoms":[33],"(e.g.,":[34],"hypersomnia,":[35],"interpersonal":[36],"sensitivity,":[37],"leaden":[38],"paralysis,":[39],"increased":[40],"appetite":[41],"and/or":[42],"weight,":[43],"phobic":[45],"anxiety)":[46],"were":[47,193],"observed":[48],"be":[50],"responsive":[52],"MAOIs.":[54],"After":[55],"several":[56],"decades":[57],"controversy":[59],"debate,":[61],"phrase":[63],"\"with":[64],"features\"":[66],"was":[67],"added":[68],"as":[69,195],"an":[70,234],"episode":[71],"specifier":[72],"in":[73,76,107,115,213],"DSM-IV":[75,158,222],"1994.":[77],"1-year":[79],"prevalence":[80],"defined":[83],"subtype":[86,184],"is":[87,113,121,151],"approximately":[88],"1%":[89],"4%;":[91],"around":[92],"15%":[93],"29%":[95],"major":[99],"depressive":[100],"disorder":[101,142],"have":[102],"depression.":[104,162],"Hardly":[105],"\"atypical\"":[106],"contemporary":[108],"contexts,":[109],"also":[112],"common":[114],"dysthymic":[116],"bipolar":[117],"II":[118],"disorders":[119],"notable":[122],"for":[123,160,185,227],"its":[124],"early":[125],"age":[126],"at":[127],"onset,":[128],"chronic":[130],"course,":[131],"high":[133],"rates":[134],"comorbidity":[136],"social":[138],"phobia":[139],"panic":[141],"agoraphobia.":[144],"requirement":[146],"preserved":[148],"mood":[149],"reactivity":[150],"arguably":[152],"most":[154],"controversial":[155],"criteria":[159],"When":[163],"compared":[164],"melancholia,":[166],"neurobiological":[168],"profiles":[169],"are":[175],"relatively":[176],"normal.":[177],"utility":[179],"therapeutics":[187],"diminished":[188],"substantially":[189],"when":[190],"TCAs":[192],"supplanted":[194],"first-line":[196],"by":[198],"selective":[200],"serotonin":[201],"reuptake":[202],"inhibitors.":[203],"Although":[204],"introduction":[205],"safer":[207],"MAOIs":[208],"has":[209],"fostered":[210],"renewed":[211],"interest":[212],"depression,":[215],"validity":[217],"importance":[219],"definition":[223],"nosology":[229],"affective":[231],"illness":[232],"remains":[233],"open":[235],"question.":[236]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}