{"id":"https://openalex.org/W32737065","doi":null,"title":"Sexual Reward and Depression","display_name":"Sexual Reward and Depression","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W32737065","mag":"32737065"},"language":"en","primary_location":{"id":"pmh:oai:ir.lib.uwo.ca:etd-2202","doi":null,"is_oa":true,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2202&context=etd","pdf_url":"https://uwo.scholaris.ca/bitstreams/6e7cdab3-8d97-4900-98ff-44dc845cd038/download","source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Thesis and Dissertation Repository","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://uwo.scholaris.ca/bitstreams/6e7cdab3-8d97-4900-98ff-44dc845cd038/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042351951","display_name":"Di Sebastiano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Di Sebastiano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5032893854","display_name":"R. Carvalho Andrea","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Carvalho Andrea","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00253493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.023399999365210533,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sexual-reward","display_name":"sexual reward","score":0.8849999904632568},{"id":"https://openalex.org/keywords/depression-like-behavior","display_name":"depression-like behavior","score":0.8180000185966492},{"id":"https://openalex.org/keywords/orexin","display_name":"orexin","score":0.8889999985694885},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.7369999885559082},{"id":"https://openalex.org/keywords/sexual-behavior","display_name":"sexual behavior","score":0.625},{"id":"https://openalex.org/keywords/sexual-abstinence","display_name":"sexual abstinence","score":0.8159999847412109},{"id":"https://openalex.org/keywords/anhedonia","display_name":"anhedonia","score":0.8820000290870667},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.9380000233650208},{"id":"https://openalex.org/keywords/paraventricular-nucleus","display_name":"paraventricular nucleus","score":0.9539999961853027},{"id":"https://openalex.org/keywords/mesolimbic-pathway","display_name":"mesolimbic system","score":0.8659999966621399},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.8709999918937683},{"id":"https://openalex.org/keywords/drug-craving","display_name":"drug craving","score":0.7329999804496765},{"id":"https://openalex.org/keywords/addiction-vulnerability","display_name":"addiction vulnerability","score":0.7120000123977661},{"id":"https://openalex.org/keywords/male-rats","display_name":"male rats","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C2778941446","wikidata":"https://www.wikidata.org/wiki/Q545365","display_name":"Anhedonia","level":3,"score":0.6933614015579224},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6674798727035522},{"id":"https://openalex.org/C143661069","wikidata":"https://www.wikidata.org/wiki/Q670713","display_name":"Reward system","level":2,"score":0.6485120058059692},{"id":"https://openalex.org/C2779680196","wikidata":"https://www.wikidata.org/wiki/Q410857","display_name":"Orexin","level":4,"score":0.6244946122169495},{"id":"https://openalex.org/C2778577535","wikidata":"https://www.wikidata.org/wiki/Q215127","display_name":"Sexual arousal","level":3,"score":0.5477088093757629},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.4688454866409302},{"id":"https://openalex.org/C64948172","wikidata":"https://www.wikidata.org/wiki/Q1653277","display_name":"Brain stimulation reward","level":4,"score":0.44890186190605164},{"id":"https://openalex.org/C2779541405","wikidata":"https://www.wikidata.org/wiki/Q498902","display_name":"Craving","level":3,"score":0.4287698566913605},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.42008212208747864},{"id":"https://openalex.org/C2993290233","wikidata":"https://www.wikidata.org/wiki/Q608","display_name":"Sexual behavior","level":2,"score":0.3406910300254822},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.32635653018951416},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3175097703933716},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.3029111623764038},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.239711731672287},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.23249897360801697},{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.17705675959587097},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15663817524909973},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.11409330368041992},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:ir.lib.uwo.ca:etd-2202","doi":null,"is_oa":true,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2202&context=etd","pdf_url":"https://uwo.scholaris.ca/bitstreams/6e7cdab3-8d97-4900-98ff-44dc845cd038/download","source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Thesis and Dissertation Repository","raw_type":"text"},{"id":"pmh:oai:uwo.scholaris.ca:20.500.14721/32932","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/20.500.14721/32932","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:32737065","doi":null,"is_oa":false,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2202&context=etd","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ir.lib.uwo.ca:etd-2202","doi":null,"is_oa":true,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2202&context=etd","pdf_url":"https://uwo.scholaris.ca/bitstreams/6e7cdab3-8d97-4900-98ff-44dc845cd038/download","source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Thesis and Dissertation Repository","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W32737065.pdf","grobid_xml":"https://content.openalex.org/works/W32737065.grobid-xml"},"referenced_works_count":227,"referenced_works":["https://openalex.org/W18078213","https://openalex.org/W26111232","https://openalex.org/W34704636","https://openalex.org/W84932982","https://openalex.org/W121409461","https://openalex.org/W194617494","https://openalex.org/W1482425500","https://openalex.org/W1501004659","https://openalex.org/W1562768501","https://openalex.org/W1627229807","https://openalex.org/W1820118415","https://openalex.org/W1961990310","https://openalex.org/W1962474939","https://openalex.org/W1964069769","https://openalex.org/W1964288151","https://openalex.org/W1965307435","https://openalex.org/W1966330898","https://openalex.org/W1966891747","https://openalex.org/W1967108382","https://openalex.org/W1968147041","https://openalex.org/W1970074433","https://openalex.org/W1970342446","https://openalex.org/W1970959827","https://openalex.org/W1971437356","https://openalex.org/W1972861207","https://openalex.org/W1974253960","https://openalex.org/W1975792359","https://openalex.org/W1976133432","https://openalex.org/W1979089109","https://openalex.org/W1979949814","https://openalex.org/W1980101257","https://openalex.org/W1981654563","https://openalex.org/W1981971544","https://openalex.org/W1982179824","https://openalex.org/W1982589738","https://openalex.org/W1982962897","https://openalex.org/W1983298714","https://openalex.org/W1983771548","https://openalex.org/W1983869923","https://openalex.org/W1984890670","https://openalex.org/W1986781795","https://openalex.org/W1986959306","https://openalex.org/W1987208323","https://openalex.org/W1988743639","https://openalex.org/W1989619235","https://openalex.org/W1990613148","https://openalex.org/W1991837129","https://openalex.org/W1991882455","https://openalex.org/W1992874462","https://openalex.org/W1993320404","https://openalex.org/W1994044626","https://openalex.org/W1994325017","https://openalex.org/W1996040798","https://openalex.org/W1996743601","https://openalex.org/W2002518106","https://openalex.org/W2003674988","https://openalex.org/W2003872770","https://openalex.org/W2005285448","https://openalex.org/W2005377956","https://openalex.org/W2005594217","https://openalex.org/W2006261940","https://openalex.org/W2007376383","https://openalex.org/W2007758784","https://openalex.org/W2007816528","https://openalex.org/W2008360236","https://openalex.org/W2013655437","https://openalex.org/W2015484182","https://openalex.org/W2015967091","https://openalex.org/W2017168736","https://openalex.org/W2018040121","https://openalex.org/W2019164797","https://openalex.org/W2020286809","https://openalex.org/W2021950821","https://openalex.org/W2022099726","https://openalex.org/W2023501491","https://openalex.org/W2024183517","https://openalex.org/W2025005051","https://openalex.org/W2025105246","https://openalex.org/W2025746674","https://openalex.org/W2026972964","https://openalex.org/W2027740042","https://openalex.org/W2028121897","https://openalex.org/W2030973124","https://openalex.org/W2031811366","https://openalex.org/W2033314153","https://openalex.org/W2033717313","https://openalex.org/W2033745381","https://openalex.org/W2034169221","https://openalex.org/W2035202887","https://openalex.org/W2036456480","https://openalex.org/W2037400256","https://openalex.org/W2038523539","https://openalex.org/W2039808373","https://openalex.org/W2041011955","https://openalex.org/W2041549838","https://openalex.org/W2041731336","https://openalex.org/W2042045791","https://openalex.org/W2042357379","https://openalex.org/W2043545748","https://openalex.org/W2044331640","https://openalex.org/W2046640433","https://openalex.org/W2047689667","https://openalex.org/W2047738112","https://openalex.org/W2047798788","https://openalex.org/W2049088920","https://openalex.org/W2049459298","https://openalex.org/W2050021971","https://openalex.org/W2050836998","https://openalex.org/W2050906665","https://openalex.org/W2051778074","https://openalex.org/W2051831861","https://openalex.org/W2052429448","https://openalex.org/W2053359936","https://openalex.org/W2053400076","https://openalex.org/W2054092950","https://openalex.org/W2055161357","https://openalex.org/W2055430040","https://openalex.org/W2055747883","https://openalex.org/W2056862933","https://openalex.org/W2057670077","https://openalex.org/W2058640434","https://openalex.org/W2060644077","https://openalex.org/W2062106032","https://openalex.org/W2062283948","https://openalex.org/W2063465809","https://openalex.org/W2065060780","https://openalex.org/W2065311276","https://openalex.org/W2066044455","https://openalex.org/W2066457796","https://openalex.org/W2066767364","https://openalex.org/W2066901457","https://openalex.org/W2067672386","https://openalex.org/W2067814202","https://openalex.org/W2068523799","https://openalex.org/W2071531229","https://openalex.org/W2072024872","https://openalex.org/W2072154498","https://openalex.org/W2073775590","https://openalex.org/W2073861307","https://openalex.org/W2074104060","https://openalex.org/W2074617349","https://openalex.org/W2076359108","https://openalex.org/W2078426468","https://openalex.org/W2078939610","https://openalex.org/W2079636816","https://openalex.org/W2084275874","https://openalex.org/W2084556601","https://openalex.org/W2085632406","https://openalex.org/W2085847387","https://openalex.org/W2087334617","https://openalex.org/W2088409879","https://openalex.org/W2088450404","https://openalex.org/W2088632365","https://openalex.org/W2088751222","https://openalex.org/W2089299823","https://openalex.org/W2091474004","https://openalex.org/W2092000722","https://openalex.org/W2093326924","https://openalex.org/W2093594342","https://openalex.org/W2098766452","https://openalex.org/W2098772655","https://openalex.org/W2100556608","https://openalex.org/W2103261141","https://openalex.org/W2103848983","https://openalex.org/W2104281464","https://openalex.org/W2105119061","https://openalex.org/W2106623141","https://openalex.org/W2106862702","https://openalex.org/W2108025834","https://openalex.org/W2111038577","https://openalex.org/W2111736770","https://openalex.org/W2112090640","https://openalex.org/W2114280375","https://openalex.org/W2114794569","https://openalex.org/W2117480181","https://openalex.org/W2118238128","https://openalex.org/W2118659222","https://openalex.org/W2119222668","https://openalex.org/W2119587745","https://openalex.org/W2120352095","https://openalex.org/W2122973173","https://openalex.org/W2124281635","https://openalex.org/W2127722821","https://openalex.org/W2129357751","https://openalex.org/W2131498774","https://openalex.org/W2131820654","https://openalex.org/W2133058739","https://openalex.org/W2133610130","https://openalex.org/W2135562556","https://openalex.org/W2137296158","https://openalex.org/W2139476920","https://openalex.org/W2140682945","https://openalex.org/W2144495096","https://openalex.org/W2145864819","https://openalex.org/W2147611554","https://openalex.org/W2152014257","https://openalex.org/W2152211310","https://openalex.org/W2154666474","https://openalex.org/W2156581621","https://openalex.org/W2156873270","https://openalex.org/W2158256695","https://openalex.org/W2159040523","https://openalex.org/W2159061031","https://openalex.org/W2159582607","https://openalex.org/W2163815564","https://openalex.org/W2164509516","https://openalex.org/W2165955755","https://openalex.org/W2166133075","https://openalex.org/W2166374999","https://openalex.org/W2169378022","https://openalex.org/W2171521575","https://openalex.org/W2197078876","https://openalex.org/W2286024109","https://openalex.org/W2307353306","https://openalex.org/W2324899490","https://openalex.org/W2340183926","https://openalex.org/W2398202798","https://openalex.org/W2403898749","https://openalex.org/W2409360789","https://openalex.org/W2411076144","https://openalex.org/W2415027054","https://openalex.org/W2428017570","https://openalex.org/W2588707619","https://openalex.org/W2885386535","https://openalex.org/W3022052974","https://openalex.org/W4322696862","https://openalex.org/W4406058881"],"related_works":["https://openalex.org/W2022099726","https://openalex.org/W1979089109","https://openalex.org/W2409360789","https://openalex.org/W60106300","https://openalex.org/W1995221719","https://openalex.org/W7221490053","https://openalex.org/W2099246616","https://openalex.org/W7098064246","https://openalex.org/W7010268824","https://openalex.org/W4366605721"],"abstract_inverted_index":{"Sexual":[0],"behavior":[1,9,145,199,234,252],"in":[2,19,38,53,71,96,118,134,146,151,235,263,275,308,323],"male":[3,147,238,309],"rats":[4,148,239,310],"is":[5,61,94,101,166],"a":[6,35,115,130,169,218,294,313],"complex":[7],"rewarding":[8],"and":[10,13,25,43,59,79,98,159,247,270,289,301],"many":[11],"neurotransmitters":[12],"neuropeptides":[14],"play":[15,34,114],"an":[16,177,278],"important":[17],"role":[18,37,49,117,131],"mediation":[20],"of":[21,45,50,55,86,120,164,171,184,191,230,250,258,267,297,305,320],"sexual":[22,56,77,105,121,144,174,185,198,306],"performance,":[23,57],"motivation":[24,58],"reward.":[26,80,122,186],"The":[27,162],"hypothalamic":[28],"neuropeptide":[29,52],"orexin":[30,69,87,93,110,133],"has":[31],"been":[32],"shown":[33,67,112,142],"key":[36],"reward":[39,60,137,209,307,322],"associated":[40,254],"with":[41,255],"food":[42],"drugs":[44],"abuse,":[46],"but":[47,100,222],"the":[48,72,152,188,264,268],"this":[51,135,192],"control":[54,119],"currently":[62],"unclear.":[63],"First,":[64],"it":[65,89],"was":[66,90,111,215,253],"that":[68,92,143,217,303],"neurons":[70,88],"hypothalamus":[73,269],"are":[74],"activated":[75],"during":[76],"performance":[78,106],"Next,":[81],"using":[82],"cell":[83],"specific":[84],"lesions":[85],"demonstrated":[91,216],"involved":[95],"arousal":[97],"anxiety,":[99],"not":[102,223],"critical":[103,116],"for":[104,132,180,204],"or":[107,226],"motivation.":[108],"Moreover,":[109],"to":[113,208,277,315],"Thus,":[123,187,281],"these":[124,282],"studies":[125,140,283],"provided":[126],"novel":[127,285],"information":[128,286],"regarding":[129],"natural":[136],"behavior.":[138,213],"Recent":[139],"have":[141],"causes":[149,232],"neuroplasticity":[150],"mesolimbic":[153],"system,":[154],"enhanced":[155],"psychostimulant-induced":[156],"locomotor":[157],"activity":[158,274],"drug":[160],"craving.":[161],"latter":[163],"which":[165],"dependent":[167],"on":[168,287],"period":[170,229,296],"abstinence":[172,196,231,298],"from":[173,197,299],"behavior,":[175],"suggesting":[176],"increased":[178,202,242,256,271],"vulnerability":[179,203],"addiction":[181],"following":[182,293,318],"loss":[183,304,319],"next":[189],"goal":[190],"thesis":[193],"determined":[194],"if":[195],"also":[200],"leads":[201],"other":[205],"disorders":[206],"related":[207],"processing,":[210],"specifically":[211],"depression-like":[212,233,251],"It":[214],"prolonged":[219,295],"(28":[220],"day)":[221,228],"short":[224],"(1":[225],"7":[227],"sexually":[236],"experienced":[237],"seen":[240],"as":[241],"passive":[243],"stress":[244],"coping":[245],"behaviors":[246],"anhedonia.":[248],"Development":[249],"levels":[257],"corticotropin":[259],"releasing":[260],"factor":[261],"mRNA":[262],"paraventricular":[265],"nucleus":[266],"hypothalamic-pituitary-adrenal":[272],"axis":[273],"response":[276],"acute":[279],"stressor.":[280],"provide":[284],"behavioral":[288],"neuroplastic":[290],"alterations":[291],"observed":[292],"mating":[300],"suggest":[302],"may":[311],"be":[312],"paradigm":[314],"study":[316],"depression":[317],"social":[321],"humans.":[324]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}