{"id":"https://openalex.org/W324734061","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","title":"Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements.","display_name":"Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements.","publication_year":1986,"publication_date":"1986-12-01","ids":{"openalex":"https://openalex.org/W324734061","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","mag":"324734061","pmid":"https://pubmed.ncbi.nlm.nih.gov/3102227","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167319"},"language":"en","primary_location":{"id":"doi:10.1002/j.1460-2075.1986.tb04636.x","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","pdf_url":null,"source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167319","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109839535","display_name":"Uwe Schlokat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U. Schlokat","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044917668","display_name":"Dirk Bohmann","orcid":"https://orcid.org/0000-0003-2362-9461","observed_orcids":["https://orcid.org/0000-0003-2362-9461"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Bohmann","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078962332","display_name":"Hans Robert Sch\u00f6ler","orcid":"https://orcid.org/0000-0003-2643-5136","observed_orcids":["https://orcid.org/0000-0003-2643-5136","https://orcid.org/0000-0002-7422-8847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Sch\u00f6ler","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"P. Gruss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Gruss","raw_affiliation_strings":["Search for more papers by this author"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Search for more papers by this author","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":6.1877,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.97320733,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"5","issue":"12","first_page":"3251","last_page":"3258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-enhancer","display_name":"immunoglobulin heavy chain enhancer","score":0.9810000061988831},{"id":"https://openalex.org/keywords/nuclear-factor-binding","display_name":"nuclear factor binding","score":0.699999988079071},{"id":"https://openalex.org/keywords/hela-cell-extracts","display_name":"HeLa cell extracts","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cell-type-specificity","display_name":"cell type specificity","score":0.6890000104904175},{"id":"https://openalex.org/keywords/transcriptional-enhancement","display_name":"transcriptional enhancement","score":0.7609999775886536},{"id":"https://openalex.org/keywords/enhancer-binding-sites","display_name":"enhancer binding sites","score":0.4230000078678131}],"concepts":[{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.8465675115585327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7188554406166077},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5211374759674072},{"id":"https://openalex.org/C96007430","wikidata":"https://www.wikidata.org/wiki/Q3776943","display_name":"Immunoglobulin heavy chain","level":3,"score":0.5142766833305359},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4644117057323456},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44963499903678894},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.44177085161209106},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4343228340148926},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3897086977958679},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3700112998485565},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33110666275024414},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005809","descriptor_name":"Genes, Regulator","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007143","descriptor_name":"Immunoglobulin Heavy Chains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013463","descriptor_name":"Sulfuric Acid Esters","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.1460-2075.1986.tb04636.x","doi":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1986.tb04636.x","pdf_url":null,"source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:195161","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167319","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1167319","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167319","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"},{"id":"pmid:3102227","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3102227","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:195161","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1167319","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W126863029","https://openalex.org/W145927914","https://openalex.org/W164839272","https://openalex.org/W183830646","https://openalex.org/W1558516755","https://openalex.org/W1591208477","https://openalex.org/W1801817680","https://openalex.org/W1857597002","https://openalex.org/W1941685106","https://openalex.org/W1968244375","https://openalex.org/W1971285426","https://openalex.org/W1989080074","https://openalex.org/W1996642589","https://openalex.org/W2001187632","https://openalex.org/W2002499610","https://openalex.org/W2002873026","https://openalex.org/W2013545053","https://openalex.org/W2031300940","https://openalex.org/W2038218774","https://openalex.org/W2038384307","https://openalex.org/W2038902487","https://openalex.org/W2057893650","https://openalex.org/W2058474728","https://openalex.org/W2071637061","https://openalex.org/W2074596664","https://openalex.org/W2086498983","https://openalex.org/W2088272992","https://openalex.org/W2093988305","https://openalex.org/W2233283379","https://openalex.org/W2428905324"],"related_works":["https://openalex.org/W2054779826","https://openalex.org/W2018352453","https://openalex.org/W1483930211","https://openalex.org/W2208849928","https://openalex.org/W112486650","https://openalex.org/W1971285426","https://openalex.org/W2085969709","https://openalex.org/W2088094960","https://openalex.org/W2093988305","https://openalex.org/W2088272992"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}