{"id":"https://openalex.org/W324056768","doi":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","title":"CARDIOVASCULAR ACTIONS OF TWO THROMBOXANE A2 ANALOGS","display_name":"CARDIOVASCULAR ACTIONS OF TWO THROMBOXANE A2 ANALOGS","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W324056768","doi":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","mag":"324056768"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-08-026819-4.50012-x","doi":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Physiology: Microcirculation and Capillary Exchange","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W652705455","display_name":"Cardiovascular Physiology: Microcirculation and Capillary Exchange"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110287816","display_name":"Allan M. Lefer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allan M. Lefer","raw_affiliation_strings":["Departments of Physiology and Pharmacology, Jefferson Medical Collage, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107 USA and Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physiology and Pharmacology, Jefferson Medical Collage, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107 USA and Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I149251103","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111545366","display_name":"J. Bryan Smith","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Bryan Smith","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065008454","display_name":"Kyriacos Costa Nicolaou","orcid":"https://orcid.org/0000-0001-5332-2511","observed_orcids":["https://orcid.org/0000-0001-5332-2511"]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyriacos C. Nicolaou","raw_affiliation_strings":["Departments of Physiology and Pharmacology, Jefferson Medical Collage, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107 USA and Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physiology and Pharmacology, Jefferson Medical Collage, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107 USA and Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I149251103","https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1384,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.84466019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"91","last_page":"98"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12910","display_name":"Eicosanoids and Hypertension Pharmacology","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12910","display_name":"Eicosanoids and Hypertension Pharmacology","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.02449999935925007,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thromboxane-a2","display_name":"thromboxane A2","score":0.968999981880188},{"id":"https://openalex.org/keywords/thromboxane-synthase-inhibition","display_name":"thromboxane synthase inhibition","score":0.9369999766349792},{"id":"https://openalex.org/keywords/platelet-aggregation","display_name":"platelet aggregation","score":0.7860000133514404},{"id":"https://openalex.org/keywords/vasoconstriction","display_name":"vasoconstriction","score":0.8939999938011169},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.968999981880188},{"id":"https://openalex.org/keywords/arachidonic-acid-metabolites","display_name":"arachidonic acid metabolites","score":0.824999988079071},{"id":"https://openalex.org/keywords/cardiovascular-effects","display_name":"cardiovascular effects","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2781024287","wikidata":"https://www.wikidata.org/wiki/Q774909","display_name":"Thromboxane A2","level":3,"score":0.7820806503295898},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.6114109754562378},{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.5804151892662048},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.5695223212242126},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.5677493810653687},{"id":"https://openalex.org/C2776785769","wikidata":"https://www.wikidata.org/wiki/Q412212","display_name":"Thromboxane","level":3,"score":0.5401976704597473},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.48984190821647644},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4778270721435547},{"id":"https://openalex.org/C173202427","wikidata":"https://www.wikidata.org/wiki/Q408575","display_name":"Thromboxane-A synthase","level":4,"score":0.4557381272315979},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40609100461006165},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3525654673576355},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31976473331451416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.223634272813797},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1315527856349945}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-08-026819-4.50012-x","doi":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-026819-4.50012-x","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Physiology: Microcirculation and Capillary Exchange","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1966048978","https://openalex.org/W1973348440","https://openalex.org/W1974005657","https://openalex.org/W2014986415","https://openalex.org/W2020066385","https://openalex.org/W2030087792","https://openalex.org/W2052748755","https://openalex.org/W2055693070","https://openalex.org/W2070088449","https://openalex.org/W2070155894","https://openalex.org/W2078948094","https://openalex.org/W2097783293","https://openalex.org/W2329841599","https://openalex.org/W2401403563","https://openalex.org/W2949614732"],"related_works":["https://openalex.org/W1974207043","https://openalex.org/W1684751432","https://openalex.org/W1973348440","https://openalex.org/W2472735936","https://openalex.org/W2950671692","https://openalex.org/W2068591642","https://openalex.org/W2020066385","https://openalex.org/W2434699632","https://openalex.org/W410113350","https://openalex.org/W2525245272"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}