{"id":"https://openalex.org/W3215536639","doi":"https://doi.org/10.1016/j.drudis.2021.11.024","title":"Engineering nanoparticle therapeutics for impaired wound healing in diabetes","display_name":"Engineering nanoparticle therapeutics for impaired wound healing in diabetes","publication_year":2021,"publication_date":"2021-11-25","ids":{"openalex":"https://openalex.org/W3215536639","doi":"https://doi.org/10.1016/j.drudis.2021.11.024","mag":"3215536639","pmid":"https://pubmed.ncbi.nlm.nih.gov/34839040"},"language":"en","primary_location":{"id":"doi:10.1016/j.drudis.2021.11.024","doi":"https://doi.org/10.1016/j.drudis.2021.11.024","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.drudis.2021.11.024","pdf_url":null,"source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ir.lib.uwo.ca/chemengpub/13","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042698270","display_name":"Yasmeen Shamiya","orcid":"https://orcid.org/0000-0003-4698-049X","observed_orcids":["https://orcid.org/0000-0003-4698-049X"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Yasmeen Shamiya","raw_affiliation_strings":["Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003625457","display_name":"Shruthi Polla Ravi","orcid":"https://orcid.org/0000-0001-7161-0322","observed_orcids":["https://orcid.org/0000-0001-7161-0322"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Shruthi Polla Ravi","raw_affiliation_strings":["School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082101656","display_name":"Ali Coyle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ali Coyle","raw_affiliation_strings":["School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030435077","display_name":"Subrata Chakrabarti","orcid":"https://orcid.org/0000-0002-0208-1401","observed_orcids":["https://orcid.org/0000-0002-0208-1401"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Subrata Chakrabarti","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, The University of Western Ontario, London, ON N6A 5B9, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026041461","display_name":"Arghya Paul","orcid":"https://orcid.org/0000-0003-4788-0378","observed_orcids":["https://orcid.org/0000-0003-4788-0378"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Arghya Paul","raw_affiliation_strings":["Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada; School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada; Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada; The Centre for Advanced Materials and Biomaterials Research, The University of Western Ontario, London, ON N6A 5B7, Canada. Electronic address: arghya.paul@uwo.ca","Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada","School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","The Centre for Advanced Materials and Biomaterials Research, The University of Western Ontario, London, ON N6A 5B7, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada; School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada; Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada; The Centre for Advanced Materials and Biomaterials Research, The University of Western Ontario, London, ON N6A 5B7, Canada. Electronic address: arghya.paul@uwo.ca","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Chemistry, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"School of Biomedical Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"The Centre for Advanced Materials and Biomaterials Research, The University of Western Ontario, London, ON N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026041461"],"corresponding_institution_ids":["https://openalex.org/I125749732"],"apc_list":{"value":4680,"currency":"USD","value_usd":4680},"apc_paid":null,"fwci":1.4627,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.83509352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"27","issue":"4","first_page":"1156","last_page":"1166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanotherapeutics","display_name":"nanotherapeutics","score":0.8610000014305115},{"id":"https://openalex.org/keywords/diabetic-wound-healing","display_name":"diabetic wound healing","score":0.9110000133514404},{"id":"https://openalex.org/keywords/diabetic-wounds","display_name":"diabetic wounds","score":0.6510000228881836},{"id":"https://openalex.org/keywords/functionalized-nanoparticles","display_name":"functionalized nanoparticles","score":0.7940000295639038},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.6389999985694885},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.5410000085830688},{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.46000000834465027},{"id":"https://openalex.org/keywords/vascularization","display_name":"vascularization","score":0.47600001096725464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7812820672988892},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7217234373092651},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.6936829090118408},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.465317964553833},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43180811405181885},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3776247203350067},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.35116416215896606},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2997211217880249},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21563094854354858},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.10992223024368286},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.09003624320030212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07627913355827332},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.drudis.2021.11.024","doi":"https://doi.org/10.1016/j.drudis.2021.11.024","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.drudis.2021.11.024","pdf_url":null,"source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},{"id":"pmid:34839040","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34839040","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug discovery today","raw_type":"Journal Article"},{"id":"pmh:oai:ir.lib.uwo.ca:chemengpub-1008","doi":null,"is_oa":true,"landing_page_url":"https://ir.lib.uwo.ca/chemengpub/13","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemical and Biochemical Engineering Publications","raw_type":"article"},{"id":"pmh:oai:uwo.scholaris.ca:20.500.14721/9269","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.drudis.2021.11.024","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:ir.lib.uwo.ca:chemengpub-1008","doi":null,"is_oa":true,"landing_page_url":"https://ir.lib.uwo.ca/chemengpub/13","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemical and Biochemical Engineering Publications","raw_type":"article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W901067443","https://openalex.org/W1434198994","https://openalex.org/W1492468638","https://openalex.org/W1969806743","https://openalex.org/W1975489435","https://openalex.org/W1976915466","https://openalex.org/W1981231226","https://openalex.org/W1984761779","https://openalex.org/W1986308133","https://openalex.org/W1991352840","https://openalex.org/W2005066650","https://openalex.org/W2007307087","https://openalex.org/W2013180572","https://openalex.org/W2032183129","https://openalex.org/W2032517146","https://openalex.org/W2051555684","https://openalex.org/W2059743234","https://openalex.org/W2091651320","https://openalex.org/W2100509378","https://openalex.org/W2112006376","https://openalex.org/W2119851569","https://openalex.org/W2120472250","https://openalex.org/W2130594874","https://openalex.org/W2134408498","https://openalex.org/W2169536045","https://openalex.org/W2169553434","https://openalex.org/W2171954743","https://openalex.org/W2187976253","https://openalex.org/W2220643393","https://openalex.org/W2296711033","https://openalex.org/W2336166906","https://openalex.org/W2340093557","https://openalex.org/W2344408149","https://openalex.org/W2528372173","https://openalex.org/W2573944088","https://openalex.org/W2583432609","https://openalex.org/W2605372776","https://openalex.org/W2640452423","https://openalex.org/W2731912524","https://openalex.org/W2736656516","https://openalex.org/W2748188663","https://openalex.org/W2786119245","https://openalex.org/W2792280168","https://openalex.org/W2794650959","https://openalex.org/W2795652485","https://openalex.org/W2890167612","https://openalex.org/W2892222389","https://openalex.org/W2898415565","https://openalex.org/W2899194788","https://openalex.org/W2899515413","https://openalex.org/W2902282736","https://openalex.org/W2913747816","https://openalex.org/W2913888889","https://openalex.org/W2915401970","https://openalex.org/W2942917768","https://openalex.org/W2953577809","https://openalex.org/W2967610984","https://openalex.org/W2980389467","https://openalex.org/W2981718947","https://openalex.org/W2983697961","https://openalex.org/W2985135065","https://openalex.org/W2986920479","https://openalex.org/W2988783747","https://openalex.org/W3004644991","https://openalex.org/W3008530588","https://openalex.org/W3008623138","https://openalex.org/W3010302794","https://openalex.org/W3015781843","https://openalex.org/W3020506972","https://openalex.org/W3033246761","https://openalex.org/W3037395110","https://openalex.org/W3037791971","https://openalex.org/W3052105661","https://openalex.org/W3088230333","https://openalex.org/W3109510179","https://openalex.org/W3111523920","https://openalex.org/W3119675889","https://openalex.org/W3155849457","https://openalex.org/W3158186945","https://openalex.org/W3161685573"],"related_works":["https://openalex.org/W4415710471","https://openalex.org/W3037395110","https://openalex.org/W4401252943","https://openalex.org/W7223461556","https://openalex.org/W4280568805","https://openalex.org/W4394956646","https://openalex.org/W3118873480","https://openalex.org/W4381432077","https://openalex.org/W4404121513","https://openalex.org/W4310716505"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-12-06T00:00:00"}
