{"id":"https://openalex.org/W3215055369","doi":"https://doi.org/10.1016/j.omtm.2021.11.012","title":"miRNA-mediated control of exogenous OCT4 during mesenchymal-epithelial transition increases measles vector reprogramming efficiency","display_name":"miRNA-mediated control of exogenous OCT4 during mesenchymal-epithelial transition increases measles vector reprogramming efficiency","publication_year":2021,"publication_date":"2021-11-29","ids":{"openalex":"https://openalex.org/W3215055369","doi":"https://doi.org/10.1016/j.omtm.2021.11.012","mag":"3215055369","pmid":"https://pubmed.ncbi.nlm.nih.gov/34977272","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8683617"},"language":"en","primary_location":{"id":"doi:10.1016/j.omtm.2021.11.012","doi":"https://doi.org/10.1016/j.omtm.2021.11.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.omtm.2021.11.012","pdf_url":null,"source":{"id":"https://openalex.org/S2764588101","display_name":"Molecular Therapy \u2014 Methods & Clinical Development","issn_l":"2329-0501","issn":["2329-0501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Methods &amp; Clinical Development","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.omtm.2021.11.012","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019444366","display_name":"Ramya Rallabandi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramya Rallabandi","raw_affiliation_strings":["Regenerative Sciences PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regenerative Sciences PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032568512","display_name":"Brenna Sharp","orcid":"https://orcid.org/0000-0001-8500-7284","observed_orcids":["https://orcid.org/0000-0001-8500-7284"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brenna Sharp","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":"https://orcid.org/0000-0001-8500-7284","affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Conrad Cruz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Conrad Cruz","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057707491","display_name":"Qi Wang","orcid":"https://orcid.org/0000-0002-0854-6505","observed_orcids":["https://orcid.org/0000-0002-0854-6505"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qi Wang","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085438055","display_name":"Alexis Locsin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis Locsin","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071498156","display_name":"Christopher B. Driscoll","orcid":"https://orcid.org/0000-0002-8629-1798","observed_orcids":["https://orcid.org/0000-0002-8629-1798"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher B. Driscoll","raw_affiliation_strings":["Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":"https://orcid.org/0000-0002-8629-1798","affiliations":[{"raw_affiliation_string":"Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ella Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ella Lee","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004245176","display_name":"T.R. Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tim Nelson","raw_affiliation_strings":["Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041207966","display_name":"Patricia Devaux","orcid":"https://orcid.org/0000-0002-5345-8336","observed_orcids":["https://orcid.org/0000-0002-5345-8336"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patricia Devaux","raw_affiliation_strings":["Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","Regenerative Sciences PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Regenerative Sciences PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Virology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041207966"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":{"value":3900,"currency":"USD","value_usd":3900},"fwci":0.3919,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.52742322,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"24","issue":null,"first_page":"48","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oct4","display_name":"Oct4","score":0.8019999861717224},{"id":"https://openalex.org/keywords/microrna-targeting","display_name":"microRNA targeting","score":0.7979999780654907},{"id":"https://openalex.org/keywords/measles-virus-vector","display_name":"measles virus vector","score":0.6019999980926514},{"id":"https://openalex.org/keywords/induced-pluripotent-stem-cell-reprogramming","display_name":"induced pluripotent stem cell reprogramming","score":0.8980000019073486},{"id":"https://openalex.org/keywords/mesenchymal-epithelial-transition","display_name":"mesenchymal-epithelial transition","score":0.9869999885559082},{"id":"https://openalex.org/keywords/reprogramming-efficiency","display_name":"reprogramming efficiency","score":0.7879999876022339},{"id":"https://openalex.org/keywords/sox2","display_name":"SOX2","score":0.9490000009536743},{"id":"https://openalex.org/keywords/klf4","display_name":"KLF4","score":0.9990000128746033},{"id":"https://openalex.org/keywords/c-myc","display_name":"c-Myc","score":0.9990000128746033},{"id":"https://openalex.org/keywords/transgene-expression-regulation","display_name":"transgene expression regulation","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.9358842372894287},{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.7800082564353943},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5925367474555969},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5543060302734375},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.5197114944458008},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.4370206594467163},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3274116516113281},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20182675123214722},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.19757914543151855},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12908825278282166}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.omtm.2021.11.012","doi":"https://doi.org/10.1016/j.omtm.2021.11.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.omtm.2021.11.012","pdf_url":null,"source":{"id":"https://openalex.org/S2764588101","display_name":"Molecular Therapy \u2014 Methods & Clinical Development","issn_l":"2329-0501","issn":["2329-0501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Methods &amp; Clinical Development","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8683617","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8683617","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Ther Methods Clin Dev","raw_type":"Text"},{"id":"pmid:34977272","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34977272","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular therapy. Methods & clinical development","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:d5505c92bc60416a8c02b0004ec47737","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d5505c92bc60416a8c02b0004ec47737","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 48-61 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.omtm.2021.11.012","doi":"https://doi.org/10.1016/j.omtm.2021.11.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.omtm.2021.11.012","pdf_url":null,"source":{"id":"https://openalex.org/S2764588101","display_name":"Molecular Therapy \u2014 Methods & Clinical Development","issn_l":"2329-0501","issn":["2329-0501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Therapy - Methods &amp; Clinical Development","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3788026050","display_name":"Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts","funder_award_id":"R01HL147852","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4777816300","display_name":null,"funder_award_id":"RMM 092319 DS 005","funder_id":"https://openalex.org/F4320317000","funder_display_name":"Regenerative Medicine Minnesota"},{"id":"https://openalex.org/G6887217874","display_name":null,"funder_award_id":"RMM 102516 002","funder_id":"https://openalex.org/F4320317000","funder_display_name":"Regenerative Medicine Minnesota"},{"id":"https://openalex.org/G7709005828","display_name":"Measles vectors for genomic modification-free induced pluripotent stem cells","funder_award_id":"R21AI105233","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8657157638","display_name":"Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts","funder_award_id":"R56HL147852","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000866180","display_name":"Mayo Clinic Comprehensive Cancer Center Support Grant","funder_award_id":"P30CA015083","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000910943","display_name":"PhD Training Program in Virology and Gene Therapy","funder_award_id":"T32AI132165","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320317000","display_name":"Regenerative Medicine Minnesota","ror":"https://ror.org/02cn62b25"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W175872487","https://openalex.org/W1945652054","https://openalex.org/W1969015262","https://openalex.org/W1974012180","https://openalex.org/W1975304818","https://openalex.org/W1979513200","https://openalex.org/W1981088384","https://openalex.org/W1984649733","https://openalex.org/W1988176484","https://openalex.org/W1989069389","https://openalex.org/W1989850689","https://openalex.org/W1990102187","https://openalex.org/W1999389272","https://openalex.org/W2000368359","https://openalex.org/W2004280138","https://openalex.org/W2010120612","https://openalex.org/W2010461414","https://openalex.org/W2010672807","https://openalex.org/W2011566302","https://openalex.org/W2013434241","https://openalex.org/W2017438799","https://openalex.org/W2019284666","https://openalex.org/W2019585591","https://openalex.org/W2031904940","https://openalex.org/W2037188673","https://openalex.org/W2039457478","https://openalex.org/W2041343947","https://openalex.org/W2047036934","https://openalex.org/W2051684781","https://openalex.org/W2053911973","https://openalex.org/W2056394508","https://openalex.org/W2059357290","https://openalex.org/W2077981848","https://openalex.org/W2078787428","https://openalex.org/W2088420183","https://openalex.org/W2092381624","https://openalex.org/W2096508370","https://openalex.org/W2104613814","https://openalex.org/W2109344960","https://openalex.org/W2125987139","https://openalex.org/W2142046859","https://openalex.org/W2148474950","https://openalex.org/W2153156044","https://openalex.org/W2168458927","https://openalex.org/W2178776036","https://openalex.org/W2289963017","https://openalex.org/W2402482204","https://openalex.org/W2414333934","https://openalex.org/W2560392010","https://openalex.org/W2573731673","https://openalex.org/W2585409470","https://openalex.org/W2605484695","https://openalex.org/W2777899495","https://openalex.org/W2793063256","https://openalex.org/W2801932471","https://openalex.org/W2900659284","https://openalex.org/W2909263500","https://openalex.org/W2911479194","https://openalex.org/W2971630541","https://openalex.org/W2972664546","https://openalex.org/W2986751328","https://openalex.org/W3081699640","https://openalex.org/W3135350120","https://openalex.org/W4242567827","https://openalex.org/W4246607912","https://openalex.org/W6655193201","https://openalex.org/W6791420905"],"related_works":["https://openalex.org/W2903914761","https://openalex.org/W7139926467","https://openalex.org/W2083462941","https://openalex.org/W2156286304","https://openalex.org/W2143971829","https://openalex.org/W2014105176","https://openalex.org/W2911479194","https://openalex.org/W2104613814","https://openalex.org/W2748091333","https://openalex.org/W2009194442"],"abstract_inverted_index":{"OCT4":[0,21,43,63],"is":[1,64,73,90],"a":[2,102,109],"key":[3],"mediator":[4],"of":[5,19,41,57,70,83,96,105,137],"induced":[6],"pluripotent":[7],"stem":[8],"cell":[9],"(iPSC)":[10],"reprogramming,":[11],"but":[12],"the":[13,17,50,53,68,76,80,93,97,115,135],"mechanistic":[14],"insights":[15],"into":[16],"role":[18],"exogenous":[20,42,62],"and":[22,72,88],"timelines":[23],"that":[24,61],"initiate":[25],"pluripotency":[26],"remain":[27],"to":[28,44,52,112,119,130],"be":[29,128],"resolved.":[30],"Here,":[31],"using":[32],"measles":[33],"reprogramming":[34,71,122],"vectors,":[35],"we":[36,100],"present":[37],"microRNA":[38],"(miRNA)":[39],"targeting":[40,107],"shut":[45],"down":[46],"its":[47],"expression":[48,82],"during":[49],"mesenchymal":[51],"epithelial":[54],"transition":[55],"phase":[56],"reprogramming.":[58],"We":[59],"showed":[60],"required":[65],"only":[66],"for":[67,75,92,133],"initiation":[69],"dispensable":[74],"maturation":[77,94],"stage.":[78],"However,":[79],"continuous":[81],"SOX2":[84],",":[85,87],"KLF4":[86],"c-MYC":[89],"necessary":[91],"stage":[95],"iPSC.":[98],"Additionally,":[99],"demonstrate":[101],"novel":[103,125],"application":[104],"miRNA":[106],"in":[108],"viral":[110],"vector":[111],"contextually":[113],"control":[114],"vector/transgene,":[116],"ultimately":[117],"leading":[118],"an":[120],"improved":[121],"efficiency.":[123],"This":[124],"approach":[126],"could":[127],"applied":[129],"other":[131],"systems":[132],"improving":[134],"efficiency":[136],"vector-induced":[138],"processes.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2021-12-06T00:00:00"}
