{"id":"https://openalex.org/W3214831815","doi":"https://doi.org/10.1172/jci127171","title":"MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model","display_name":"MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model","publication_year":2021,"publication_date":"2021-11-30","ids":{"openalex":"https://openalex.org/W3214831815","doi":"https://doi.org/10.1172/jci127171","mag":"3214831815","pmid":"https://pubmed.ncbi.nlm.nih.gov/34850744","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8631602"},"language":"en","primary_location":{"id":"doi:10.1172/jci127171","doi":"https://doi.org/10.1172/jci127171","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci127171","pdf_url":"http://www.jci.org/articles/view/127171/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jci.org/articles/view/127171/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Pathricia Veronica Tilstam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pathricia Veronica Tilstam","raw_affiliation_strings":["Department of Immunology, Harvard Medical School, Boston, Massachusetts, USA","Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wibke Schulte","orcid":"https://orcid.org/0000-0001-5776-0447","observed_orcids":["https://orcid.org/0000-0001-5776-0447"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Wibke Schulte","raw_affiliation_strings":["Berlin Institute of Health (BIH), Berlin, Germany","Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","Department of Surgery, Campus Charit\u00e9 Mitte, Campus Virchow-Klinikum, Charit\u00e9, Universit\u00e4tsmedizin Berlin, Berlin, Germany","Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-5776-0447","affiliations":[{"raw_affiliation_string":"Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Surgery, Campus Charit\u00e9 Mitte, Campus Virchow-Klinikum, Charit\u00e9, Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Thomas Holowka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Holowka","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bong-Sung Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Bong-Sung Kim","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","Department of Plastic, Reconstructive and Hand Surgery, RWTH Aachen University, Aachen, Germany","Division of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Plastic, Reconstructive and Hand Surgery, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]},{"raw_affiliation_string":"Division of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jessica Nouws","orcid":"https://orcid.org/0000-0003-3347-3595","observed_orcids":["https://orcid.org/0000-0003-3347-3595"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Nouws","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0003-3347-3595","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017993625","display_name":"Maor Sauler","orcid":"https://orcid.org/0000-0001-5240-7978","observed_orcids":["https://orcid.org/0000-0001-5240-7978"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maor Sauler","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-5240-7978","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Marta Piecychna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marta Piecychna","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039426621","display_name":"Georgios Pantouris","orcid":"https://orcid.org/0000-0001-5547-1406","observed_orcids":["https://orcid.org/0000-0001-5547-1406"]},"institutions":[{"id":"https://openalex.org/I119942576","display_name":"University of the Pacific","ror":"https://ror.org/05ma4gw77","country_code":"US","type":"education","lineage":["https://openalex.org/I119942576"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Georgios Pantouris","raw_affiliation_strings":["Department of Chemistry, University of the Pacific, Stockton, California, USA","Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-5547-1406","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of the Pacific, Stockton, California, USA","institution_ids":["https://openalex.org/I119942576"]},{"raw_affiliation_string":"Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Elias Lolis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elias Lolis","raw_affiliation_strings":["Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lin Leng","orcid":"https://orcid.org/0000-0002-0605-358X","observed_orcids":["https://orcid.org/0000-0002-0605-358X"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lin Leng","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0002-0605-358X","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J\u00fcrgen Bernhagen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113080","display_name":"Munich Cluster for Systems Neurology","ror":"https://ror.org/025z3z560","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210113080","https://openalex.org/I62916508","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405259612","display_name":"Institut f\u00fcr Schlaganfall- und Demenzforschung","ror":"https://ror.org/02fa5cb34","country_code":"DE","type":"education","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405259612","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen Bernhagen","raw_affiliation_strings":["Department of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-University Munich, Munich, Germany","Munich Cluster for Systems Neurology, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-University Munich, Munich, Germany","institution_ids":["https://openalex.org/I4405259612","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Munich Cluster for Systems Neurology, Munich, Germany","institution_ids":["https://openalex.org/I4210113080"]}]},{"author_position":"middle","author":{"id":null,"display_name":"G\u00fcnter Fingerle-Rowson","orcid":"https://orcid.org/0000-0002-6621-7590","observed_orcids":["https://orcid.org/0000-0002-6621-7590"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G\u00fcnter Fingerle-Rowson","raw_affiliation_strings":["Department I of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen Bonn K\u00f6ln D\u00fcsseldorf, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6621-7590","affiliations":[{"raw_affiliation_string":"Department I of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen Bonn K\u00f6ln D\u00fcsseldorf, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"last","author":{"id":null,"display_name":"Richard Bucala","orcid":"https://orcid.org/0000-0001-5783-5736","observed_orcids":["https://orcid.org/0000-0001-5783-5736"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Bucala","raw_affiliation_strings":["Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-5783-5736","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":4.0255,"has_fulltext":true,"cited_by_count":77,"citation_normalized_percentile":{"value":0.95692308,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"131","issue":"23","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13254","display_name":"Macrophage Migration Inhibitory Factor","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13254","display_name":"Macrophage Migration Inhibitory Factor","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macrophage-migration-inhibitory-factor","display_name":"macrophage migration inhibitory factor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/d-dopachrome-tautomerase","display_name":"D-dopachrome tautomerase","score":0.9539999961853027},{"id":"https://openalex.org/keywords/polymicrobial-sepsis","display_name":"polymicrobial sepsis","score":0.984000027179718},{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":0.8040000200271606},{"id":"https://openalex.org/keywords/macrophage-recruitment","display_name":"macrophage recruitment","score":0.9710000157356262},{"id":"https://openalex.org/keywords/cxcr2","display_name":"CXCR2","score":0.7089999914169312},{"id":"https://openalex.org/keywords/cd74","display_name":"CD74","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.800000011920929},{"id":"https://openalex.org/keywords/mif-knockout-mice","display_name":"MIF knockout mice","score":0.7419999837875366},{"id":"https://openalex.org/keywords/adoptive-transfer","display_name":"adoptive transfer","score":0.7310000061988831},{"id":"https://openalex.org/keywords/sepsis-mortality","display_name":"sepsis mortality","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C104177226","wikidata":"https://www.wikidata.org/wiki/Q15311903","display_name":"Macrophage migration inhibitory factor","level":3,"score":0.9243999719619751},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6869999766349792},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.666700005531311},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6452000141143799},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.565500020980835},{"id":"https://openalex.org/C2776001837","wikidata":"https://www.wikidata.org/wiki/Q9629","display_name":"Peritoneum","level":2,"score":0.5307999849319458},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.4945000112056732},{"id":"https://openalex.org/C84913492","wikidata":"https://www.wikidata.org/wiki/Q5014892","display_name":"CXC chemokine receptors","level":5,"score":0.4702000021934509},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.43650001287460327},{"id":"https://openalex.org/C119997001","wikidata":"https://www.wikidata.org/wiki/Q21113110","display_name":"CD74","level":5,"score":0.4253000020980835},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.41429999470710754},{"id":"https://openalex.org/C2780199535","wikidata":"https://www.wikidata.org/wiki/Q223102","display_name":"Peritonitis","level":2,"score":0.40070000290870667},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.3831000030040741},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.3806000053882599},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.352400004863739},{"id":"https://openalex.org/C110015553","wikidata":"https://www.wikidata.org/wiki/Q5009623","display_name":"CCL3","level":5,"score":0.351500004529953},{"id":"https://openalex.org/C54166955","wikidata":"https://www.wikidata.org/wiki/Q658145","display_name":"Chemotaxis","level":3,"score":0.337799996137619},{"id":"https://openalex.org/C90375314","wikidata":"https://www.wikidata.org/wiki/Q3537484","display_name":"Adoptive cell transfer","level":4,"score":0.32899999618530273},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.31349998712539673},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30309998989105225},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.28290000557899475},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.2671999931335449},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.25839999318122864},{"id":"https://openalex.org/C187316574","wikidata":"https://www.wikidata.org/wiki/Q423698","display_name":"Interleukin 10","level":3,"score":0.2524000108242035}],"mesh":[{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008263","descriptor_name":"Macrophage Migration-Inhibitory Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008263","descriptor_name":"Macrophage Migration-Inhibitory Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010533","descriptor_name":"Peritoneal Lavage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019746","descriptor_name":"Intramolecular Oxidoreductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019746","descriptor_name":"Intramolecular Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1172/jci127171","doi":"https://doi.org/10.1172/jci127171","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci127171","pdf_url":"http://www.jci.org/articles/view/127171/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8631602","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8631602","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Invest","raw_type":"Text"},{"id":"pmid:34850744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34850744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical investigation","raw_type":"Journal Article"},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:60061","doi":null,"is_oa":false,"landing_page_url":"https://kups.ub.uni-koeln.de/60061/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"pmh:oai:www.zora.uzh.ch:213911","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/id/eprint/213911/1/127171.1-20211123143218-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf","pdf_url":"https://www.zora.uzh.ch/id/eprint/213911/1/127171.1-20211123143218-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf","source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Tilstam, Pathricia Veronica; Schulte, Wibke; Holowka, Thomas; Kim, Bong-Sung; Nouws, Jessica; Sauler, Maor; Piecychna, Marta; Pantouris, Georgios; Lolis, Elias; Leng, Lin; Bernhagen, J\u00fcrgen; Fingerle-Rowson, G\u00fcnter; Bucala, Richard (2021). MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model. Journal of Clinical Investigation, 131(23):e127171.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:scholarlycommons.pacific.edu:all-faculty-1268","doi":null,"is_oa":true,"landing_page_url":"https://scholarlycommons.pacific.edu/all-faculty/269","pdf_url":"https://scholarlycommons.pacific.edu/context/all-faculty/article/1268/viewcontent/MIF_20but_20not_20MIF_2_20recruits.pdf","source":{"id":"https://openalex.org/S4306400314","display_name":"Scholarly Commons (University of the Pacific)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119942576","host_organization_name":"University of the Pacific","host_organization_lineage":["https://openalex.org/I119942576"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pacific Faculty Work","raw_type":"text"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/191991","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/191991","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tilstam, P. V., Schulte, W., Holowka, T., Kim, B.-S., Nouws, J., Sauler, M., Piecychna, M., Pantouris, G., Lolis, E., Leng, L., Bernhagen, J., Fingerle-Rowson, G., & Bucala, R. (2021). MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model. Journal of Clinical Investigation, 131, e127171. https://doi.org/10.1172/JCI127171","raw_type":"Journal Article"},{"id":"doi:10.5167/uzh-213911","doi":"https://doi.org/10.5167/uzh-213911","is_oa":true,"landing_page_url":"https://doi.org/10.5167/uzh-213911","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1172/jci127171","doi":"https://doi.org/10.1172/jci127171","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci127171","pdf_url":"http://www.jci.org/articles/view/127171/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1208489275","display_name":null,"funder_award_id":"START 2013-2","funder_id":"https://openalex.org/F4320324232","funder_display_name":"RWTH Aachen University"},{"id":"https://openalex.org/G1901460537","display_name":null,"funder_award_id":"SFB1123","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G2073351111","display_name":"Aging and Innate Immune Mechanisms in Pulmonary Infection","funder_award_id":"R01HL130669","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2313112155","display_name":null,"funder_award_id":"548970","funder_id":"https://openalex.org/F4320306237","funder_display_name":"Arthritis Foundation"},{"id":"https://openalex.org/G2329167175","display_name":"Mechanisms of Rheumatoid Synovial Fibroblast Activation","funder_award_id":"R01AR049610","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2523809757","display_name":null,"funder_award_id":"START 2013","funder_id":"https://openalex.org/F4320324232","funder_display_name":"RWTH Aachen University"},{"id":"https://openalex.org/G2699147485","display_name":null,"funder_award_id":"SFB 1123/A03,BE1977/7-1,BE1977/11-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3537957661","display_name":null,"funder_award_id":"691346","funder_id":"https://openalex.org/F4320324232","funder_display_name":"RWTH Aachen University"},{"id":"https://openalex.org/G4358246839","display_name":"MIF and DNA repair in the emphysematous lung","funder_award_id":"K08HL135402","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4776778319","display_name":null,"funder_award_id":"KI1973/1\u20101","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4966563573","display_name":null,"funder_award_id":"SFB1123-A03","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G6045158739","display_name":null,"funder_award_id":"SCHU2851/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G670216319","display_name":null,"funder_award_id":"BE 1977/11-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G754071303","display_name":null,"funder_award_id":"SCHU2851/1-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G804482151","display_name":null,"funder_award_id":"AR049610","funder_id":"https://openalex.org/F4320308380","funder_display_name":"Yale University"},{"id":"https://openalex.org/G9000874706","display_name":"Role of MIF and CD74 in the pathogenesis of emphysema","funder_award_id":"R01HL155948","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000879731","display_name":"Defining the Pathogenic Contribution of High Genotypic MIF Expression","funder_award_id":"R01AR078334","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G9000905448","display_name":"Yale Clinical and Translational Science Award","funder_award_id":"UL1TR001863","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G914439352","display_name":null,"funder_award_id":"BE1977/7-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320306237","display_name":"Arthritis Foundation","ror":"https://ror.org/04zk9fe75"},{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321526","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25"},{"id":"https://openalex.org/F4320324232","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3214831815.pdf","grobid_xml":"https://content.openalex.org/works/W3214831815.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1553047467","https://openalex.org/W1559226045","https://openalex.org/W1574734561","https://openalex.org/W1734802175","https://openalex.org/W1863224167","https://openalex.org/W1951483940","https://openalex.org/W1966778344","https://openalex.org/W1973610607","https://openalex.org/W1988250064","https://openalex.org/W1989947080","https://openalex.org/W1992695048","https://openalex.org/W1998389471","https://openalex.org/W1999039574","https://openalex.org/W2000987923","https://openalex.org/W2005965937","https://openalex.org/W2009675488","https://openalex.org/W2021208474","https://openalex.org/W2023945291","https://openalex.org/W2024977803","https://openalex.org/W2029174607","https://openalex.org/W2032439102","https://openalex.org/W2034694813","https://openalex.org/W2044224359","https://openalex.org/W2046208657","https://openalex.org/W2046525356","https://openalex.org/W2062824264","https://openalex.org/W2083513831","https://openalex.org/W2087968772","https://openalex.org/W2090056328","https://openalex.org/W2093816949","https://openalex.org/W2097065948","https://openalex.org/W2098572294","https://openalex.org/W2098865069","https://openalex.org/W2105518626","https://openalex.org/W2110740878","https://openalex.org/W2115681156","https://openalex.org/W2115927163","https://openalex.org/W2124973240","https://openalex.org/W2134192536","https://openalex.org/W2138593954","https://openalex.org/W2141458291","https://openalex.org/W2150683218","https://openalex.org/W2156261200","https://openalex.org/W2166190627","https://openalex.org/W2166820820","https://openalex.org/W2169628454","https://openalex.org/W2300371428","https://openalex.org/W2404328745","https://openalex.org/W2416306437","https://openalex.org/W2551295874","https://openalex.org/W2588354313","https://openalex.org/W2595850199","https://openalex.org/W2618137629","https://openalex.org/W2620241325","https://openalex.org/W2807642785","https://openalex.org/W2888865579","https://openalex.org/W2971979257","https://openalex.org/W3173034620","https://openalex.org/W4313359442"],"related_works":["https://openalex.org/W4313358931","https://openalex.org/W3109908215","https://openalex.org/W2896852700","https://openalex.org/W7030011005","https://openalex.org/W2152058417","https://openalex.org/W7100949974","https://openalex.org/W2083342592","https://openalex.org/W2889486197","https://openalex.org/W7057457739","https://openalex.org/W2141901742"],"abstract_inverted_index":{"Excessive":[0],"inflammation":[1],"drives":[2],"the":[3,102,122,137,149,169],"progression":[4],"from":[5],"sepsis":[6,68],"to":[7,66,94],"septic":[8],"shock.":[9],"Macrophage":[10],"migration":[11],"inhibitory":[12],"factor":[13],"(MIF)":[14],"is":[15],"of":[16,45,57,86,109,118,130,140,173],"interest":[17],"because":[18],"MIF":[19,48,110,123,154,167],"promoter":[20],"polymorphisms":[21],"predict":[22],"mortality":[23],"in":[24,32,92,143,153,168],"different":[25],"infections,":[26],"and":[27,63,69,121,126,159,171],"anti-MIF":[28],"antibody":[29],"improves":[30],"survival":[31,72],"experimental":[33],"models":[34],"when":[35],"administered":[36],"8":[37],"hours":[38],"after":[39],"infectious":[40],"insult.":[41],"The":[42],"recent":[43],"description":[44],"a":[46,71,163],"second":[47],"superfamily":[49],"member,":[50],"D-dopachrome":[51],"tautomerase":[52],"(D-DT/MIF-2),":[53],"prompted":[54],"closer":[55],"investigation":[56],"MIF-dependent":[58],"responses.":[59],"We":[60],"subjected":[61],"Mif-/-":[62,134],"Mif-2-/-":[64],"mice":[65],"polymicrobial":[67,144],"observed":[70],"benefit":[73],"with":[74,83],"Mif":[75,141],"but":[76,113],"not":[77],"Mif-2":[78],"deficiency.":[79],"Survival":[80],"was":[81],"associated":[82],"reduced":[84,136],"numbers":[85],"small":[87],"peritoneal":[88,96,103],"macrophages":[89,97],"(SPMs)":[90],"that,":[91],"contrast":[93],"large":[95],"(LPMs),":[98],"were":[99],"recruited":[100],"into":[101,133],"cavity.":[104],"LPMs":[105],"produced":[106],"higher":[107,116],"quantities":[108],"than":[111],"SPMs,":[112],"SPMs":[114,132],"expressed":[115],"levels":[117],"inflammatory":[119,174],"cytokines":[120],"receptors":[124],"CD74":[125],"CXCR2.":[127],"Adoptive":[128],"transfer":[129],"WT":[131],"hosts":[135],"protective":[138],"effect":[139],"deficiency":[142],"sepsis.":[145],"Notably,":[146],"MIF-2":[147],"lacks":[148],"pseudo-(E)LR":[150],"motif":[151],"present":[152],"that":[155],"mediates":[156],"CXCR2":[157],"engagement":[158],"SPM":[160],"migration,":[161],"supporting":[162],"specific":[164],"role":[165],"for":[166],"recruitment":[170],"accumulation":[172],"SPMs.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-12-06T00:00:00"}