{"id":"https://openalex.org/W3214420052","doi":"https://doi.org/10.1016/s0167-8140(21)08803-4","title":"4: Chemoradiation With or Without Metformin in Locally Advanced Cervical Cancer: Phase II Randomized Trial","display_name":"4: Chemoradiation With or Without Metformin in Locally Advanced Cervical Cancer: Phase II Randomized Trial","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3214420052","doi":"https://doi.org/10.1016/s0167-8140(21)08803-4","mag":"3214420052"},"language":"en","primary_location":{"id":"doi:10.1016/s0167-8140(21)08803-4","doi":"https://doi.org/10.1016/s0167-8140(21)08803-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0167-8140(21)08803-4","pdf_url":null,"source":{"id":"https://openalex.org/S144507673","display_name":"Radiotherapy and Oncology","issn_l":"0167-8140","issn":["0167-8140","1879-0887"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034829322","display_name":"Kathy Chai-Zung Han","orcid":"https://orcid.org/0000-0001-8439-3929","observed_orcids":["https://orcid.org/0000-0001-8439-3929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathy Han","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082234108","display_name":"Anthony Fyles","orcid":"https://orcid.org/0000-0002-3633-2483","observed_orcids":["https://orcid.org/0000-0002-3633-2483"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony Fyles","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034391155","display_name":"Tina L. T. Shek","orcid":"https://orcid.org/0000-0002-1865-6097","observed_orcids":["https://orcid.org/0000-0002-1865-6097"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tina Shek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032770101","display_name":"Jennifer M. Croke","orcid":"https://orcid.org/0000-0002-7090-6313","observed_orcids":["https://orcid.org/0000-0002-7090-6313"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer Croke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019722619","display_name":"Neesha C. Dhani","orcid":"https://orcid.org/0000-0002-0410-6932","observed_orcids":["https://orcid.org/0000-0002-0410-6932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neesha Dhani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074984859","display_name":"David Paul D'Souza","orcid":"https://orcid.org/0000-0001-5093-7107","observed_orcids":["https://orcid.org/0000-0001-5093-7107"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David D\u2019Souza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013499153","display_name":"Ting\u2010Yim Lee","orcid":"https://orcid.org/0000-0001-7605-9752","observed_orcids":["https://orcid.org/0000-0001-7605-9752"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ting-Yim Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077793054","display_name":"Naz Chaudary","orcid":"https://orcid.org/0000-0002-8021-3182","observed_orcids":["https://orcid.org/0000-0002-8021-3182"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naz Chaudary","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032935393","display_name":"Rob A. Cairns","orcid":"https://orcid.org/0000-0001-9540-7927","observed_orcids":["https://orcid.org/0000-0001-9540-7927"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rob Cairns","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031467567","display_name":"Melania Pintilie","orcid":"https://orcid.org/0000-0002-8238-8365","observed_orcids":["https://orcid.org/0000-0002-8238-8365"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Melania Pintilie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016850642","display_name":"Douglass C. Vines","orcid":"https://orcid.org/0000-0001-7560-1079","observed_orcids":["https://orcid.org/0000-0001-7560-1079"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Douglass Vines","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008048551","display_name":"David Anthony Jaffray","orcid":"https://orcid.org/0000-0001-7378-7543","observed_orcids":["https://orcid.org/0000-0001-7378-7543"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Jaffray","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065405706","display_name":"Ur Metser","orcid":"https://orcid.org/0000-0003-3726-8994","observed_orcids":["https://orcid.org/0000-0003-3726-8994"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ur Metser","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064900626","display_name":"Michael Milosevic","orcid":"https://orcid.org/0000-0002-9620-6876","observed_orcids":["https://orcid.org/0000-0002-9620-6876"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Milosevic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5021850993","display_name":"Marianne Koritzinsky","orcid":"https://orcid.org/0000-0003-0547-2480","observed_orcids":["https://orcid.org/0000-0003-0547-2480"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marianne Koritzinsky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2740,"currency":"USD","value_usd":2740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.29536178,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"163","issue":null,"first_page":"S5","last_page":"S5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"chemoradiotherapy","score":0.8799999952316284},{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/locally-advanced-cervical-cancer","display_name":"locally advanced cervical cancer","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7717921137809753},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6891180872917175},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.6480246782302856},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6281692981719971},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5163522958755493},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.4829108715057373},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3155052661895752},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0167-8140(21)08803-4","doi":"https://doi.org/10.1016/s0167-8140(21)08803-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0167-8140(21)08803-4","pdf_url":null,"source":{"id":"https://openalex.org/S144507673","display_name":"Radiotherapy and Oncology","issn_l":"0167-8140","issn":["0167-8140","1879-0887"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4238042970","https://openalex.org/W4410561574","https://openalex.org/W2734772938","https://openalex.org/W2030075421","https://openalex.org/W4232385034","https://openalex.org/W2994475888","https://openalex.org/W2001805644","https://openalex.org/W2517062526","https://openalex.org/W4391121908","https://openalex.org/W4234279306"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2021-11-22T00:00:00"}