{"id":"https://openalex.org/W3214212675","doi":"https://doi.org/10.3390/biomedicines9111708","title":"Progress on Genetic Basis of Primary Aldosteronism","display_name":"Progress on Genetic Basis of Primary Aldosteronism","publication_year":2021,"publication_date":"2021-11-17","ids":{"openalex":"https://openalex.org/W3214212675","doi":"https://doi.org/10.3390/biomedicines9111708","mag":"3214212675","pmid":"https://pubmed.ncbi.nlm.nih.gov/34829937","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8615950"},"language":"en","primary_location":{"id":"doi:10.3390/biomedicines9111708","doi":"https://doi.org/10.3390/biomedicines9111708","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines9111708","pdf_url":"https://www.mdpi.com/2227-9059/9/11/1708/pdf?version=1637162413","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3214212675"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2227-9059/9/11/1708/pdf?version=1637162413","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059732754","display_name":"Izabela Karwacka","orcid":"https://orcid.org/0000-0001-8910-206X","observed_orcids":["https://orcid.org/0000-0001-8910-206X"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Izabela Karwacka","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland"],"raw_orcid":"https://orcid.org/0000-0001-8910-206X","affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031873967","display_name":"\u0141ukasz Obo\u0142o\u0144czyk","orcid":"https://orcid.org/0000-0002-7975-271X","observed_orcids":["https://orcid.org/0000-0002-7975-271X"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"\u0141ukasz Obo\u0142o\u0144czyk","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038159131","display_name":"Sonia Kaniuka\u2010Jakubowska","orcid":"https://orcid.org/0000-0001-6894-8648","observed_orcids":["https://orcid.org/0000-0001-6894-8648"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Sonia Kaniuka-Jakubowska","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028351766","display_name":"Micha\u0142 Bohdan","orcid":"https://orcid.org/0000-0002-3496-2238","observed_orcids":["https://orcid.org/0000-0002-3496-2238"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Micha\u0142 Bohdan","raw_affiliation_strings":["First Department of Cardiology, Medical University of Gdansk, 80-952 Gda\u0144sk, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Cardiology, Medical University of Gdansk, 80-952 Gda\u0144sk, Poland","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061173528","display_name":"Krzysztof Sworczak","orcid":"https://orcid.org/0000-0002-9866-5670","observed_orcids":["https://orcid.org/0000-0002-9866-5670"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Krzysztof Sworczak","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gda\u0144sk, 80-952 Gda\u0144sk, Poland","institution_ids":["https://openalex.org/I75124487"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059732754"],"corresponding_institution_ids":["https://openalex.org/I75124487"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2160},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2160},"fwci":0.2778,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.27306567,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"9","issue":"11","first_page":"1708","last_page":"1708"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-aldosteronism","display_name":"primary aldosteronism","score":1.0},{"id":"https://openalex.org/keywords/genetic-basis","display_name":"genetic basis","score":0.9309999942779541},{"id":"https://openalex.org/keywords/aldosterone-producing-adenoma","display_name":"aldosterone-producing adenoma","score":0.9259999990463257},{"id":"https://openalex.org/keywords/bilateral-adrenal-hyperplasia","display_name":"bilateral adrenal hyperplasia","score":0.8870000243186951},{"id":"https://openalex.org/keywords/familial-hyperaldosteronism","display_name":"familial hyperaldosteronism","score":0.9380000233650208},{"id":"https://openalex.org/keywords/kcnj5","display_name":"KCNJ5","score":0.6909999847412109},{"id":"https://openalex.org/keywords/atp1a1","display_name":"ATP1A1","score":0.878000020980835},{"id":"https://openalex.org/keywords/atp2b3","display_name":"ATP2B3","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cacna1d","display_name":"CACNA1D","score":0.953000009059906},{"id":"https://openalex.org/keywords/cacna1h","display_name":"CACNA1H","score":0.984000027179718},{"id":"https://openalex.org/keywords/ion-channel-mutations","display_name":"ion channel mutations","score":0.8640000224113464},{"id":"https://openalex.org/keywords/channelopathies","display_name":"channelopathies","score":0.9430000185966492},{"id":"https://openalex.org/keywords/secondary-hypertension","display_name":"secondary hypertension","score":0.5559999942779541},{"id":"https://openalex.org/keywords/plasma-renin-activity","display_name":"plasma renin activity","score":0.7900000214576721},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":0.6129999756813049},{"id":"https://openalex.org/keywords/germline-mutations","display_name":"germline mutations","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C2780233176","wikidata":"https://www.wikidata.org/wiki/Q1939330","display_name":"Primary aldosteronism","level":3,"score":0.9306915998458862},{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.8327670097351074},{"id":"https://openalex.org/C2776292634","wikidata":"https://www.wikidata.org/wiki/Q1640860","display_name":"Hyperaldosteronism","level":3,"score":0.7363646626472473},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.7011634111404419},{"id":"https://openalex.org/C2781399356","wikidata":"https://www.wikidata.org/wiki/Q918285","display_name":"Adrenocortical carcinoma","level":2,"score":0.6284537315368652},{"id":"https://openalex.org/C2777581072","wikidata":"https://www.wikidata.org/wiki/Q987319","display_name":"Secondary hypertension","level":3,"score":0.6130467653274536},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5523123741149902},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5017011165618896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4778958559036255},{"id":"https://openalex.org/C2777428134","wikidata":"https://www.wikidata.org/wiki/Q272741","display_name":"Adenoma","level":2,"score":0.4746188223361969},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36819425225257874},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3257278800010681},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3145977258682251},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.28391164541244507},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2011304795742035},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.05848667025566101}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/biomedicines9111708","doi":"https://doi.org/10.3390/biomedicines9111708","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines9111708","pdf_url":"https://www.mdpi.com/2227-9059/9/11/1708/pdf?version=1637162413","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},{"id":"pmid:34829937","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34829937","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8615950","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8615950/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:fa1f82f2f734431ab5daddcf1a8c0822","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fa1f82f2f734431ab5daddcf1a8c0822","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomedicines, Vol 9, Iss 11, p 1708 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/biomedicines9111708","doi":"https://doi.org/10.3390/biomedicines9111708","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines9111708","pdf_url":"https://www.mdpi.com/2227-9059/9/11/1708/pdf?version=1637162413","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8999999761581421,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3214212675.pdf","grobid_xml":"https://content.openalex.org/works/W3214212675.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W561187501","https://openalex.org/W1603617892","https://openalex.org/W1750587252","https://openalex.org/W1898633796","https://openalex.org/W1967137553","https://openalex.org/W1967440935","https://openalex.org/W1976103872","https://openalex.org/W1991449126","https://openalex.org/W2001722277","https://openalex.org/W2008821347","https://openalex.org/W2014086287","https://openalex.org/W2036558738","https://openalex.org/W2048984095","https://openalex.org/W2053874415","https://openalex.org/W2063070371","https://openalex.org/W2089447911","https://openalex.org/W2091277822","https://openalex.org/W2099488003","https://openalex.org/W2109509624","https://openalex.org/W2111995467","https://openalex.org/W2112089668","https://openalex.org/W2116698088","https://openalex.org/W2120347052","https://openalex.org/W2120733806","https://openalex.org/W2130472485","https://openalex.org/W2145316463","https://openalex.org/W2146136214","https://openalex.org/W2147066085","https://openalex.org/W2154788287","https://openalex.org/W2157610967","https://openalex.org/W2160612644","https://openalex.org/W2188408455","https://openalex.org/W2336613908","https://openalex.org/W2416234919","https://openalex.org/W2427690394","https://openalex.org/W2462882541","https://openalex.org/W2519578718","https://openalex.org/W2528513517","https://openalex.org/W2560895843","https://openalex.org/W2611121922","https://openalex.org/W2618657196","https://openalex.org/W2624544718","https://openalex.org/W2760971233","https://openalex.org/W2769598244","https://openalex.org/W2772618307","https://openalex.org/W2776231146","https://openalex.org/W2784117724","https://openalex.org/W2784213451","https://openalex.org/W2789114977","https://openalex.org/W2793806343","https://openalex.org/W2801121124","https://openalex.org/W2805997389","https://openalex.org/W2852717346","https://openalex.org/W2887931962","https://openalex.org/W2890511303","https://openalex.org/W2890857439","https://openalex.org/W2903535702","https://openalex.org/W2945609295","https://openalex.org/W2954582497","https://openalex.org/W2954834847","https://openalex.org/W2981565798","https://openalex.org/W2987238063","https://openalex.org/W2997250550","https://openalex.org/W3003524758","https://openalex.org/W3003987803","https://openalex.org/W3007361206","https://openalex.org/W3015296784","https://openalex.org/W3040220837","https://openalex.org/W3092159692","https://openalex.org/W3203348660"],"related_works":["https://openalex.org/W3156810845","https://openalex.org/W2098826265","https://openalex.org/W2955582639","https://openalex.org/W3036291554","https://openalex.org/W4285587115","https://openalex.org/W3133639020","https://openalex.org/W2970384786","https://openalex.org/W4315785403","https://openalex.org/W3001203335","https://openalex.org/W4211042286"],"abstract_inverted_index":{"Primary":[0],"aldosteronism":[1],"(PA)":[2],"is":[3,25,40,50],"a":[4,43,55,109,112],"heterogeneous":[5],"group":[6],"of":[7,14,19,34,46,66,71,104,115,130,161,178],"disorders":[8,70],"caused":[9,53],"by":[10,54],"the":[11,29,90,101,127,137,162,185],"autonomous":[12],"overproduction":[13],"aldosterone":[15],"with":[16,42,193],"simultaneous":[17],"suppression":[18],"plasma":[20],"renin":[21],"activity":[22],"(PRA).":[23],"It":[24],"considered":[26],"to":[27,125],"be":[28,126,191],"most":[30,51],"common":[31],"endocrine":[32],"cause":[33,129],"secondary":[35],"arterial":[36],"hypertension":[37],"(HT)":[38],"and":[39,80,85,133,153,170,198],"associated":[41,192],"high":[44],"rate":[45],"cardiovascular":[47],"complications.":[48],"PA":[49,67,189],"often":[52],"bilateral":[56],"adrenal":[57],"hyperplasia":[58],"(BAH)":[59],"or":[60],"aldosterone-producing":[61,82,87,131],"adenoma":[62],"(APA);":[63],"rarer":[64],"causes":[65],"include":[68],"genetic":[69,102],"steroidogenesis":[72],"(familial":[73],"hyperaldosteronism":[74],"(FA)":[75],"type":[76],"I,":[77],"II,":[78],"III":[79],"IV),":[81],"adrenocortical":[83],"carcinoma,":[84],"ectopic":[86],"tumors.":[88],"Over":[89],"last":[91],"few":[92],"years,":[93],"significant":[94],"progress":[95],"has":[96],"been":[97,143,156,173],"made":[98],"towards":[99],"understanding":[100],"basis":[103],"PA,":[105],"classifying":[106],"it":[107],"as":[108],"channelopathy.":[110],"Recently,":[111],"growing":[113],"body":[114],"clinical":[116],"evidence":[117],"suggests":[118],"that":[119],"mutations":[120,135,146,167],"in":[121,147,158,168,175],"ion":[122,138],"channels":[123],"appear":[124],"major":[128],"adenomas,":[132],"several":[134],"within":[136],"channel":[139],"encoding":[140],"genes":[141,149],"have":[142,155,172],"identified.":[144],"Somatic":[145],"four":[148],"(KCNJ5,":[150],"ATP1A1,":[151],"ATP2B3":[152],"CACNA1D)":[154],"identified":[157],"nearly":[159],"60%":[160],"sporadic":[163],"APAs,":[164],"while":[165],"germline":[166],"KCNJ5":[169],"CACNA1H":[171],"reported":[174],"different":[176],"subtypes":[177],"familial":[179],"hyperaldosteronism.":[180],"These":[181],"new":[182],"insights":[183],"into":[184],"molecular":[186],"mechanisms":[187],"underlying":[188],"may":[190],"potential":[194],"implications":[195],"for":[196],"diagnosis":[197],"therapy.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2021-11-22T00:00:00"}