{"id":"https://openalex.org/W3213529754","doi":null,"title":"Analysis of cellular responses to microwave irradiation in E. coli and change of oxygen level and culture medium in human cancer cell lines using RNA-seq based transcriptomic profiling","display_name":"Analysis of cellular responses to microwave irradiation in E. coli and change of oxygen level and culture medium in human cancer cell lines using RNA-seq based transcriptomic profiling","publication_year":2021,"publication_date":"2021-04-19","ids":{"openalex":"https://openalex.org/W3213529754","mag":"3213529754"},"language":"en","primary_location":{"id":"pmh:oai:dr.library.brocku.ca:10464/15050","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10464/15050","pdf_url":"http://hdl.handle.net/10464/15050","source":{"id":"https://openalex.org/S4306401333","display_name":"Brock University Digital Repository (Brock University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I186803428","host_organization_name":"Brock University","host_organization_lineage":["https://openalex.org/I186803428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Electronic Thesis or Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10464/15050","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039018638","display_name":"Eunike Ilona Hilson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Eunike Ilona Hilson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5039018638"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10874","display_name":"Electromagnetic Fields and Biological Effects","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10874","display_name":"Electromagnetic Fields and Biological Effects","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12976","display_name":"Magnetic and Electromagnetic Effects","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microwave-irradiation","display_name":"microwave irradiation","score":0.9929999709129333},{"id":"https://openalex.org/keywords/non-thermal-effects","display_name":"non-thermal effects","score":0.9269999861717224},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9919999837875366},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.6620000004768372},{"id":"https://openalex.org/keywords/breast-cancer-cell-lines","display_name":"breast cancer cell lines","score":0.6970000267028809},{"id":"https://openalex.org/keywords/prostate-cancer-cell-lines","display_name":"prostate cancer cell lines","score":0.9169999957084656},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.9089999794960022},{"id":"https://openalex.org/keywords/pc-3-cells","display_name":"PC-3 cells","score":0.9929999709129333},{"id":"https://openalex.org/keywords/oxygen-concentration","display_name":"oxygen concentration","score":0.8259999752044678},{"id":"https://openalex.org/keywords/culture-medium","display_name":"culture media","score":0.9150000214576721},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.6370000243186951},{"id":"https://openalex.org/keywords/dmem","display_name":"DMEM","score":0.47999998927116394},{"id":"https://openalex.org/keywords/differential-gene-expression","display_name":"differential gene expression","score":0.628000020980835},{"id":"https://openalex.org/keywords/membrane-integrity","display_name":"membrane integrity","score":0.6380000114440918},{"id":"https://openalex.org/keywords/dna-replication","display_name":"DNA replication","score":0.7179999947547913},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"cell cycle","score":0.7929999828338623},{"id":"https://openalex.org/keywords/viral-carcinogenesis","display_name":"viral oncogenesis","score":0.9290000200271606},{"id":"https://openalex.org/keywords/legionnaires-disease","display_name":"Legionnaires' disease","score":0.9570000171661377}],"concepts":[{"id":"https://openalex.org/C107397762","wikidata":"https://www.wikidata.org/wiki/Q2542347","display_name":"RNA-Seq","level":5,"score":0.7854154706001282},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.666311502456665},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.5854735970497131},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.46881866455078125},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43384069204330444},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3957338035106659},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3554374575614929},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3518948554992676},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3267107605934143},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.24244114756584167},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20996442437171936},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18606704473495483},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16515177488327026},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:dr.library.brocku.ca:10464/15050","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10464/15050","pdf_url":"http://hdl.handle.net/10464/15050","source":{"id":"https://openalex.org/S4306401333","display_name":"Brock University Digital Repository (Brock University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I186803428","host_organization_name":"Brock University","host_organization_lineage":["https://openalex.org/I186803428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Electronic Thesis or Dissertation"},{"id":"pmh:oai:brocku.scholaris.ca:10464/15050","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10464/15050","pdf_url":null,"source":{"id":"https://openalex.org/S4306401333","display_name":"Brock University Digital Repository (Brock University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I186803428","host_organization_name":"Brock University","host_organization_lineage":["https://openalex.org/I186803428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},{"id":"mag:3213529754","doi":null,"is_oa":false,"landing_page_url":"https://dr.library.brocku.ca/handle/10464/15050","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:dr.library.brocku.ca:10464/15050","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10464/15050","pdf_url":"http://hdl.handle.net/10464/15050","source":{"id":"https://openalex.org/S4306401333","display_name":"Brock University Digital Repository (Brock University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I186803428","host_organization_name":"Brock University","host_organization_lineage":["https://openalex.org/I186803428"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Electronic Thesis or Dissertation"},"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3213529754.pdf","grobid_xml":"https://content.openalex.org/works/W3213529754.grobid-xml"},"referenced_works_count":199,"referenced_works":["https://openalex.org/W53492560","https://openalex.org/W70178801","https://openalex.org/W73080040","https://openalex.org/W151021435","https://openalex.org/W374191801","https://openalex.org/W819780422","https://openalex.org/W1450273840","https://openalex.org/W1481478029","https://openalex.org/W1518907982","https://openalex.org/W1525014224","https://openalex.org/W1541844738","https://openalex.org/W1546232003","https://openalex.org/W1603560807","https://openalex.org/W1905028982","https://openalex.org/W1960424936","https://openalex.org/W1964803183","https://openalex.org/W1968458420","https://openalex.org/W1971375261","https://openalex.org/W1972558089","https://openalex.org/W1973094248","https://openalex.org/W1976247738","https://openalex.org/W1983375287","https://openalex.org/W1986585821","https://openalex.org/W1989238861","https://openalex.org/W1989367702","https://openalex.org/W1992372128","https://openalex.org/W1997778770","https://openalex.org/W1998502755","https://openalex.org/W1998973728","https://openalex.org/W1999574084","https://openalex.org/W2005363422","https://openalex.org/W2011657487","https://openalex.org/W2013318867","https://openalex.org/W2018722597","https://openalex.org/W2022909023","https://openalex.org/W2024354448","https://openalex.org/W2027179140","https://openalex.org/W2032964150","https://openalex.org/W2037936898","https://openalex.org/W2043110235","https://openalex.org/W2044013892","https://openalex.org/W2048607735","https://openalex.org/W2054716313","https://openalex.org/W2055142768","https://openalex.org/W2062865981","https://openalex.org/W2063343639","https://openalex.org/W2063562236","https://openalex.org/W2065128082","https://openalex.org/W2069295116","https://openalex.org/W2069820387","https://openalex.org/W2071558601","https://openalex.org/W2073120856","https://openalex.org/W2073715696","https://openalex.org/W2080128936","https://openalex.org/W2083793612","https://openalex.org/W2087878206","https://openalex.org/W2094257363","https://openalex.org/W2096153116","https://openalex.org/W2097065948","https://openalex.org/W2097186235","https://openalex.org/W2097647914","https://openalex.org/W2097948046","https://openalex.org/W2098734857","https://openalex.org/W2100305481","https://openalex.org/W2100381083","https://openalex.org/W2102619694","https://openalex.org/W2103017472","https://openalex.org/W2103441770","https://openalex.org/W2104005232","https://openalex.org/W2106722820","https://openalex.org/W2107060225","https://openalex.org/W2107665951","https://openalex.org/W2108357601","https://openalex.org/W2108979392","https://openalex.org/W2109741608","https://openalex.org/W2110392562","https://openalex.org/W2111237814","https://openalex.org/W2114104545","https://openalex.org/W2114504176","https://openalex.org/W2117608012","https://openalex.org/W2120835288","https://openalex.org/W2121211805","https://openalex.org/W2123221307","https://openalex.org/W2123430062","https://openalex.org/W2124097252","https://openalex.org/W2124985265","https://openalex.org/W2125013165","https://openalex.org/W2126419817","https://openalex.org/W2127274965","https://openalex.org/W2127284906","https://openalex.org/W2128677683","https://openalex.org/W2131271579","https://openalex.org/W2134526812","https://openalex.org/W2138207763","https://openalex.org/W2139007652","https://openalex.org/W2139845300","https://openalex.org/W2144675324","https://openalex.org/W2146612872","https://openalex.org/W2150306524","https://openalex.org/W2156841387","https://openalex.org/W2158217645","https://openalex.org/W2158329313","https://openalex.org/W2159584001","https://openalex.org/W2159675211","https://openalex.org/W2159707944","https://openalex.org/W2164154943","https://openalex.org/W2166550754","https://openalex.org/W2169456326","https://openalex.org/W2170219300","https://openalex.org/W2172010428","https://openalex.org/W2177517030","https://openalex.org/W2178294617","https://openalex.org/W2179438025","https://openalex.org/W2182072320","https://openalex.org/W2204695292","https://openalex.org/W2218925817","https://openalex.org/W2236822143","https://openalex.org/W2244106250","https://openalex.org/W2252367299","https://openalex.org/W2263985732","https://openalex.org/W2278569802","https://openalex.org/W2306179365","https://openalex.org/W2323326409","https://openalex.org/W2343429368","https://openalex.org/W2435507289","https://openalex.org/W2486662925","https://openalex.org/W2498090354","https://openalex.org/W2534230388","https://openalex.org/W2548700945","https://openalex.org/W2549741572","https://openalex.org/W2556834947","https://openalex.org/W2561879836","https://openalex.org/W2563427432","https://openalex.org/W2567793122","https://openalex.org/W2572178740","https://openalex.org/W2592811885","https://openalex.org/W2599138920","https://openalex.org/W2606006514","https://openalex.org/W2620925221","https://openalex.org/W2625708429","https://openalex.org/W2738186870","https://openalex.org/W2751782056","https://openalex.org/W2752894194","https://openalex.org/W2763864472","https://openalex.org/W2781500292","https://openalex.org/W2783897523","https://openalex.org/W2786663364","https://openalex.org/W2790476536","https://openalex.org/W2793057280","https://openalex.org/W2793466413","https://openalex.org/W2794543897","https://openalex.org/W2794556477","https://openalex.org/W2801789151","https://openalex.org/W2802302938","https://openalex.org/W2803013346","https://openalex.org/W2804335534","https://openalex.org/W2808182511","https://openalex.org/W2883834604","https://openalex.org/W2885852501","https://openalex.org/W2887939574","https://openalex.org/W2891919482","https://openalex.org/W2894095027","https://openalex.org/W2896573442","https://openalex.org/W2899661341","https://openalex.org/W2900166571","https://openalex.org/W2900835784","https://openalex.org/W2903796263","https://openalex.org/W2904345087","https://openalex.org/W2906327979","https://openalex.org/W2906906692","https://openalex.org/W2910083917","https://openalex.org/W2920946413","https://openalex.org/W2922210236","https://openalex.org/W2929507517","https://openalex.org/W2932374721","https://openalex.org/W2936291767","https://openalex.org/W2941550709","https://openalex.org/W2944518398","https://openalex.org/W2945788288","https://openalex.org/W2947415066","https://openalex.org/W2947415966","https://openalex.org/W2947462116","https://openalex.org/W2948369249","https://openalex.org/W2951611449","https://openalex.org/W2953281992","https://openalex.org/W2954214838","https://openalex.org/W2963367647","https://openalex.org/W2967899617","https://openalex.org/W2974676489","https://openalex.org/W2980219769","https://openalex.org/W2987284967","https://openalex.org/W2990999848","https://openalex.org/W2992219911","https://openalex.org/W2997828025","https://openalex.org/W3005357739","https://openalex.org/W3006289939","https://openalex.org/W3006868079","https://openalex.org/W3008204887","https://openalex.org/W3008441196"],"related_works":["https://openalex.org/W1638090839","https://openalex.org/W3017833507","https://openalex.org/W2936291767","https://openalex.org/W147645354","https://openalex.org/W2186043241","https://openalex.org/W2770140839","https://openalex.org/W7100532412","https://openalex.org/W1999257781","https://openalex.org/W2893296716","https://openalex.org/W3033364922"],"abstract_inverted_index":{"RNA":[0],"sequencing":[1,10,46],"(RNA-seq)":[2],"is":[3,209],"one":[4],"of":[5,8,114,127,142,148,171,174,189,284,331],"the":[6,19,27,30,34,57,96,102,111,122,128,140,146,169,186,236,252,281,306,319,329],"applications":[7],"next-generation":[9],"(NGS)":[11],"with":[12,125,154,159],"differential":[13],"gene":[14,58,103,205],"expression":[15,59,104,141,206],"(DGE)":[16],"analysis":[17,39,278],"at":[18,176,226,263],"transcriptomic":[20,187,282],"level":[21,198,214,321],"as":[22,95],"its":[23],"primary":[24],"objective.":[25],"Among":[26],"NGS":[28],"technologies,":[29],"Illumina":[31],"platforms":[32],"are":[33,235,325],"current":[35],"standard":[36],"for":[37,40,145,273],"RNA-seq":[38,54],"their":[41],"best":[42],"cost":[43],"efficiency":[44],"and":[45,72,89,134,151,191,199,215,232,286,295,297,302,308,322],"accuracy.":[47],"In":[48,157,249],"this":[49],"study,":[50],"we":[51],"employed":[52],"Illumina-based":[53],"to":[55,68,79,117,167,196,221,255],"examine":[56],"profile":[60,188,283],"change":[61,105,202],"in":[62,73,77,100,106,132,184,194,207,224,245,312,335],"E.":[63,107,118],"coli":[64,108,119],"cells":[65,120,193],"after":[66],"exposure":[67],"microwave":[69],"irradiation":[70],"(MWI)":[71],"cancer":[74,85,91,274],"cell":[75,86,92,247,275,314,332,336],"lines":[76,87,93,315],"response":[78,195],"different":[80,242,290],"culture":[81,200,216,243,260,323],"conditions":[82,244],"using":[83],"breast":[84],"(MCF7)":[88],"prostate":[90],"(PC3)":[94],"models.":[97],"Our":[98,182],"results":[99,183],"examining":[101,185],"showed":[109,203],"that":[110,204,289,318],"non-thermal":[112,172],"effects":[113,173],"MWI":[115,137,175],"led":[116],"entering":[121],"stationary":[123],"phase":[124],"most":[126,237,257],"downregulated":[129],"genes":[130,143,270],"involved":[131],"metabolic":[133],"biosynthesis":[135],"pathways.":[136],"also":[138,279],"upregulated":[139],"important":[144,272,326],"maintenance":[147],"membrane":[149],"integrity":[150],"adhesion":[152],"associated":[153],"bacterial":[155],"motility.":[156],"comparison":[158],"other":[160],"similar":[161],"studies,":[162],"our":[163],"methodology":[164],"allowed":[165],"us":[166],"observe":[168],"impact":[170],"2.45":[177],"GHz":[178],"via":[179],"simultaneous":[180],"cooling.":[181],"MCF7":[190,208,285],"PC3":[192],"oxygen":[197,213,298,320],"medium":[201,217,261,324],"highly":[210],"affected":[211,238],"by":[212,259],"changes":[218,262,305],"when":[219],"compared":[220],"PC3,":[222,250,287],"especially":[223],"DMEM":[225,294],"18%":[227,303],"O2.":[228],"DNA":[229],"replication,":[230],"cell-cycle,":[231],"viral":[233],"carcinogenesis":[234],"pathways":[239,311],"observed":[240],"from":[241],"both":[246,313],"lines.":[248],"only":[251],"legionellosis":[253],"seems":[254],"be":[256],"impacted":[258],"5%":[264],"O2,":[265],"involving":[266],"8":[267],"differentially":[268],"expressed":[269],"(DEGs),":[271],"development.":[276],"DGE":[277],"provides":[280],"showing":[288],"nutrient":[291],"composition":[292],"(between":[293],"Plasmax)":[296],"levels":[299],"(5%":[300],"O2":[301],"O2)":[304],"metabolism":[307],"various":[309],"signaling":[310],"differently":[316],"suggesting":[317],"factors":[327],"impacting":[328],"outcome":[330],"culture-based":[333],"experiments":[334],"type-specific":[337],"fashion.":[338]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-11-22T00:00:00"}
