{"id":"https://openalex.org/W3213243174","doi":"https://doi.org/10.2174/1570159x19666211111142027","title":"Neurochemical and Behavioral Consequences of Ethanol and/or Caffeine Exposure: Effects in Zebrafish and Rodents","display_name":"Neurochemical and Behavioral Consequences of Ethanol and/or Caffeine Exposure: Effects in Zebrafish and Rodents","publication_year":2021,"publication_date":"2021-11-12","ids":{"openalex":"https://openalex.org/W3213243174","doi":"https://doi.org/10.2174/1570159x19666211111142027","mag":"3213243174","pmid":"https://pubmed.ncbi.nlm.nih.gov/34766897","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9608232"},"language":"en","primary_location":{"id":"doi:10.2174/1570159x19666211111142027","doi":"https://doi.org/10.2174/1570159x19666211111142027","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1570159x19666211111142027","pdf_url":null,"source":{"id":"https://openalex.org/S85221069","display_name":"Current Neuropharmacology","issn_l":"1570-159X","issn":["1570-159X","1875-6190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Neuropharmacology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9608232","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024778277","display_name":"VICTORIA P. CONNAUGHTON","orcid":"https://orcid.org/0000-0001-6516-7299","observed_orcids":["https://orcid.org/0000-0001-6516-7299"]},"institutions":[{"id":"https://openalex.org/I181401687","display_name":"American University","ror":"https://ror.org/052w4zt36","country_code":"US","type":"education","lineage":["https://openalex.org/I181401687"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Victoria P. Connaughton","raw_affiliation_strings":["Department of Biology and Center for Neuroscience and Behavior, American University, Washington, DC 20016, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Center for Neuroscience and Behavior, American University, Washington, DC 20016, USA","institution_ids":["https://openalex.org/I181401687"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052210182","display_name":"Carly L. Clayman","orcid":"https://orcid.org/0000-0001-7677-7076","observed_orcids":["https://orcid.org/0000-0001-7677-7076"]},"institutions":[{"id":"https://openalex.org/I181401687","display_name":"American University","ror":"https://ror.org/052w4zt36","country_code":"US","type":"education","lineage":["https://openalex.org/I181401687"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carly L. Clayman","raw_affiliation_strings":["Department of Biology and Center for Neuroscience and Behavior, American University, Washington, DC 20016, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology and Center for Neuroscience and Behavior, American University, Washington, DC 20016, USA","institution_ids":["https://openalex.org/I181401687"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5024778277"],"corresponding_institution_ids":["https://openalex.org/I181401687"],"apc_list":null,"apc_paid":null,"fwci":0.7876,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.5875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"20","issue":"3","first_page":"560","last_page":"578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.01489999983459711,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethanol","display_name":"ethanol","score":0.7839999794960022},{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/co-exposure","display_name":"combined exposure","score":0.7419999837875366},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.6399999856948853},{"id":"https://openalex.org/keywords/locomotor-behavior","display_name":"locomotor behavior","score":0.6039999723434448},{"id":"https://openalex.org/keywords/teratogenicity","display_name":"teratogenicity","score":0.8159999847412109},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.6209999918937683},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adenosine","display_name":"adenosine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gaba","display_name":"GABA","score":0.9900000095367432},{"id":"https://openalex.org/keywords/novel-tank-test","display_name":"novel tank test","score":0.703000009059906},{"id":"https://openalex.org/keywords/thigmotaxis","display_name":"thigmotaxis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/shoaling-behavior","display_name":"shoaling behavior","score":0.859000027179718},{"id":"https://openalex.org/keywords/adolescent-development","display_name":"adolescent development","score":0.6169999837875366},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.8569999933242798},{"id":"https://openalex.org/keywords/rodent-models","display_name":"rodent models","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C25876315","wikidata":"https://www.wikidata.org/wiki/Q15197465","display_name":"Neurochemical","level":2,"score":0.903461217880249},{"id":"https://openalex.org/C2910500303","wikidata":"https://www.wikidata.org/wiki/Q949618","display_name":"Thigmotaxis","level":3,"score":0.8075734376907349},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.7474274635314941},{"id":"https://openalex.org/C2777765862","wikidata":"https://www.wikidata.org/wiki/Q62903","display_name":"Anxiolytic","level":3,"score":0.6453620195388794},{"id":"https://openalex.org/C205044023","wikidata":"https://www.wikidata.org/wiki/Q4778117","display_name":"Anxiogenic","level":4,"score":0.6360935568809509},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6189484596252441},{"id":"https://openalex.org/C39920043","wikidata":"https://www.wikidata.org/wiki/Q786278","display_name":"Neurochemistry","level":3,"score":0.5966886281967163},{"id":"https://openalex.org/C2778500429","wikidata":"https://www.wikidata.org/wiki/Q60235","display_name":"Caffeine","level":2,"score":0.5739706158638},{"id":"https://openalex.org/C128188215","wikidata":"https://www.wikidata.org/wiki/Q3026765","display_name":"Neuropharmacology","level":2,"score":0.5562498569488525},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.4688509404659271},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4501837491989136},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4486793875694275},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.4289018511772156},{"id":"https://openalex.org/C2780557958","wikidata":"https://www.wikidata.org/wiki/Q211036","display_name":"Stimulant","level":2,"score":0.4252266585826874},{"id":"https://openalex.org/C187714386","wikidata":"https://www.wikidata.org/wiki/Q420225","display_name":"Monoamine neurotransmitter","level":4,"score":0.41191574931144714},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34685754776000977},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27975913882255554},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20226570963859558},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.18634843826293945},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.18058964610099792},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.15980654954910278},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07886907458305359},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C2779085643","wikidata":"https://www.wikidata.org/wiki/Q7096029","display_name":"Open field","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012377","descriptor_name":"Rodentia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.2174/1570159x19666211111142027","doi":"https://doi.org/10.2174/1570159x19666211111142027","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1570159x19666211111142027","pdf_url":null,"source":{"id":"https://openalex.org/S85221069","display_name":"Current Neuropharmacology","issn_l":"1570-159X","issn":["1570-159X","1875-6190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Neuropharmacology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9608232","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9608232","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Neuropharmacol","raw_type":"Text"},{"id":"pmid:34766897","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34766897","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current neuropharmacology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9608232","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9608232","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Neuropharmacol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":239,"referenced_works":["https://openalex.org/W6854499","https://openalex.org/W26622575","https://openalex.org/W71343311","https://openalex.org/W102442439","https://openalex.org/W195255639","https://openalex.org/W1480121462","https://openalex.org/W1490848194","https://openalex.org/W1515108121","https://openalex.org/W1520157843","https://openalex.org/W1590614402","https://openalex.org/W1652348262","https://openalex.org/W1816846580","https://openalex.org/W1874199142","https://openalex.org/W1918535853","https://openalex.org/W1923423561","https://openalex.org/W1949168314","https://openalex.org/W1965569460","https://openalex.org/W1967383331","https://openalex.org/W1967528036","https://openalex.org/W1968114242","https://openalex.org/W1970586330","https://openalex.org/W1971187421","https://openalex.org/W1971556351","https://openalex.org/W1974100845","https://openalex.org/W1974102018","https://openalex.org/W1975041268","https://openalex.org/W1975256587","https://openalex.org/W1976664875","https://openalex.org/W1978110923","https://openalex.org/W1978529094","https://openalex.org/W1979090522","https://openalex.org/W1979933042","https://openalex.org/W1980471589","https://openalex.org/W1981020370","https://openalex.org/W1982604627","https://openalex.org/W1983795048","https://openalex.org/W1984123159","https://openalex.org/W1984327929","https://openalex.org/W1985336737","https://openalex.org/W1985676682","https://openalex.org/W1986795275","https://openalex.org/W1987225592","https://openalex.org/W1988061092","https://openalex.org/W1989598646","https://openalex.org/W1990133728","https://openalex.org/W1991486734","https://openalex.org/W1992578455","https://openalex.org/W1994970739","https://openalex.org/W1995060577","https://openalex.org/W1995941325","https://openalex.org/W1997953094","https://openalex.org/W1998467104","https://openalex.org/W1998550864","https://openalex.org/W1999678222","https://openalex.org/W2000885259","https://openalex.org/W2000994000","https://openalex.org/W2001331834","https://openalex.org/W2003642652","https://openalex.org/W2004984114","https://openalex.org/W2005797238","https://openalex.org/W2006268557","https://openalex.org/W2007287690","https://openalex.org/W2007638433","https://openalex.org/W2010347314","https://openalex.org/W2010701133","https://openalex.org/W2010921174","https://openalex.org/W2011044541","https://openalex.org/W2011486818","https://openalex.org/W2012358225","https://openalex.org/W2012783828","https://openalex.org/W2012904022","https://openalex.org/W2014624755","https://openalex.org/W2016322754","https://openalex.org/W2017417865","https://openalex.org/W2019142781","https://openalex.org/W2020984319","https://openalex.org/W2021483780","https://openalex.org/W2021526251","https://openalex.org/W2022644411","https://openalex.org/W2022748226","https://openalex.org/W2023226500","https://openalex.org/W2024905720","https://openalex.org/W2025186708","https://openalex.org/W2030169264","https://openalex.org/W2034359823","https://openalex.org/W2034423314","https://openalex.org/W2034726350","https://openalex.org/W2035802806","https://openalex.org/W2036169877","https://openalex.org/W2036709496","https://openalex.org/W2040223373","https://openalex.org/W2042442643","https://openalex.org/W2043632247","https://openalex.org/W2045274797","https://openalex.org/W2046063439","https://openalex.org/W2047130413","https://openalex.org/W2047563641","https://openalex.org/W2049595104","https://openalex.org/W2051558414","https://openalex.org/W2052147508","https://openalex.org/W2053251586","https://openalex.org/W2053513133","https://openalex.org/W2054705354","https://openalex.org/W2055724397","https://openalex.org/W2055913792","https://openalex.org/W2055930553","https://openalex.org/W2056862559","https://openalex.org/W2057235843","https://openalex.org/W2057636635","https://openalex.org/W2057821456","https://openalex.org/W2058613739","https://openalex.org/W2058766183","https://openalex.org/W2061361691","https://openalex.org/W2062109052","https://openalex.org/W2062581932","https://openalex.org/W2063128166","https://openalex.org/W2063604110","https://openalex.org/W2063704369","https://openalex.org/W2066733291","https://openalex.org/W2066906778","https://openalex.org/W2067438050","https://openalex.org/W2067539731","https://openalex.org/W2067709897","https://openalex.org/W2068153172","https://openalex.org/W2070968623","https://openalex.org/W2075004136","https://openalex.org/W2078169039","https://openalex.org/W2080126342","https://openalex.org/W2082140249","https://openalex.org/W2083277970","https://openalex.org/W2083859487","https://openalex.org/W2086531235","https://openalex.org/W2087036957","https://openalex.org/W2087399967","https://openalex.org/W2088044911","https://openalex.org/W2088769536","https://openalex.org/W2090497569","https://openalex.org/W2092075316","https://openalex.org/W2093386277","https://openalex.org/W2093956369","https://openalex.org/W2094107463","https://openalex.org/W2094384373","https://openalex.org/W2094913643","https://openalex.org/W2095530992","https://openalex.org/W2095829288","https://openalex.org/W2095872630","https://openalex.org/W2097301830","https://openalex.org/W2101353952","https://openalex.org/W2105562246","https://openalex.org/W2106861254","https://openalex.org/W2107157101","https://openalex.org/W2107551388","https://openalex.org/W2109386965","https://openalex.org/W2120549275","https://openalex.org/W2124691694","https://openalex.org/W2127385137","https://openalex.org/W2133180168","https://openalex.org/W2135827933","https://openalex.org/W2136717001","https://openalex.org/W2136841796","https://openalex.org/W2138287659","https://openalex.org/W2138416809","https://openalex.org/W2138495925","https://openalex.org/W2144227494","https://openalex.org/W2144586633","https://openalex.org/W2147354655","https://openalex.org/W2150266199","https://openalex.org/W2152223184","https://openalex.org/W2152246016","https://openalex.org/W2153125527","https://openalex.org/W2159213976","https://openalex.org/W2159898375","https://openalex.org/W2160526441","https://openalex.org/W2163203533","https://openalex.org/W2168576501","https://openalex.org/W2170528269","https://openalex.org/W2176676343","https://openalex.org/W2177129748","https://openalex.org/W2178736753","https://openalex.org/W2186791365","https://openalex.org/W2198095015","https://openalex.org/W2219777068","https://openalex.org/W2261918419","https://openalex.org/W2270960981","https://openalex.org/W2279553170","https://openalex.org/W2283824784","https://openalex.org/W2286860617","https://openalex.org/W2309837369","https://openalex.org/W2313954272","https://openalex.org/W2343165599","https://openalex.org/W2345540931","https://openalex.org/W2399201195","https://openalex.org/W2407027351","https://openalex.org/W2462739799","https://openalex.org/W2524665066","https://openalex.org/W2530533726","https://openalex.org/W2565077597","https://openalex.org/W2566999437","https://openalex.org/W2580672651","https://openalex.org/W2606904472","https://openalex.org/W2623673708","https://openalex.org/W2686989879","https://openalex.org/W2742332806","https://openalex.org/W2747694384","https://openalex.org/W2768013866","https://openalex.org/W2772440156","https://openalex.org/W2805455482","https://openalex.org/W2805812684","https://openalex.org/W2807183953","https://openalex.org/W2810609624","https://openalex.org/W2887882805","https://openalex.org/W2905231151","https://openalex.org/W2909989884","https://openalex.org/W2914354255","https://openalex.org/W2962958898","https://openalex.org/W2964745739","https://openalex.org/W2967305389","https://openalex.org/W2969973123","https://openalex.org/W2972020455","https://openalex.org/W2980344784","https://openalex.org/W2981125203","https://openalex.org/W2981204121","https://openalex.org/W2981635105","https://openalex.org/W2987845799","https://openalex.org/W2996015078","https://openalex.org/W2999871159","https://openalex.org/W3010565982","https://openalex.org/W3012147899","https://openalex.org/W3015603284","https://openalex.org/W3022808851","https://openalex.org/W3030966218","https://openalex.org/W3047591070","https://openalex.org/W3081418474","https://openalex.org/W3094109625","https://openalex.org/W3159153023","https://openalex.org/W4242124043","https://openalex.org/W4252035884","https://openalex.org/W4298012394","https://openalex.org/W4312519111"],"related_works":["https://openalex.org/W2623673708","https://openalex.org/W6943934078","https://openalex.org/W4383217354","https://openalex.org/W7120507198","https://openalex.org/W2566999437","https://openalex.org/W2772440156","https://openalex.org/W4414191702","https://openalex.org/W2021483780","https://openalex.org/W2686989879","https://openalex.org/W7120319158"],"abstract_inverted_index":{"Zebrafish":[0,19],"are":[1],"increasingly":[2],"being":[3],"utilized":[4],"to":[5,37,78,86],"model":[6],"the":[7,39,55,80,103,114,127,156,161],"behavioral":[8,119,136],"and":[9,27,43,58,63,88,92,118,135,144,168,198,205,221],"neurochemical":[10,183],"effects":[11,82,162],"of":[12,21,41,61,83,105,121,138,149,163,224],"pharmaceuticals":[13],"and,":[14,70],"more":[15],"recently,":[16],"pharmaceutical":[17],"interactions.":[18],"models":[20],"stress":[22],"establish":[23],"that":[24,226],"both":[25,203],"caffeine":[26,87,122,166],"ethanol":[28,164],"influence":[29],"anxiety,":[30],"though":[31],"few":[32],"studies":[33,173],"have":[34],"implemented":[35],"coadministration":[36],"assess":[38],"interaction":[40],"anxiety":[42],"reward-seeking.":[44],"Caffeine":[45],"exposure":[46,125,167],"in":[47,54,94,126,142,158,177,210,214],"zebrafish":[48,128,159,172,211],"is":[49,66,152],"teratogenic,":[50],"causing":[51],"developmental":[52],"abnormalities":[53],"cardiovascular,":[56],"neuromuscular,":[57],"nervous":[59],"systems":[60],"embryos":[62],"larvae.":[64],"Ethanol":[65],"also":[67],"a":[68,193],"teratogen":[69],"as":[71,140],"an":[72],"anxiolytic":[73],"substance,":[74],"may":[75,101],"be":[76],"able":[77],"offset":[79],"anxiogenic":[81],"caffeine.":[84],"Co-exposure":[85],"alcohol":[89,106,124],"impacts":[90],"neuroanatomy":[91],"behavior":[93],"adolescent":[95],"animal":[96],"models,":[97,216],"suggesting":[98],"stimulant":[99],"substances":[100],"moderate":[102],"impact":[104],"on":[107,131,181],"neural":[108],"circuit":[109],"development.":[110],"Here,":[111],"we":[112],"review":[113,151],"literature":[115],"describing":[116],"neuropharmacological":[117],"consequences":[120],"and/or":[123,165],"model,":[129],"focusing":[130],"neurochemistry,":[132],"locomotor":[133,199],"effects,":[134],"assessments":[137],"stress/anxiety":[139],"reported":[141],"adolescent/juvenile":[143],"adult":[145],"animals.":[146],"The":[147],"purpose":[148],"this":[150],"twofold:":[153],"(1)":[154],"describe":[155],"work":[157],"documenting":[160],"(2)":[169],"compare":[170,208],"these":[171],"with":[174,192,212],"comparable":[175],"experiments":[176],"rodents.":[178],"We":[179,207],"focus":[180],"specific":[182],"pathways":[184],"(dopamine,":[185],"serotonin,":[186],"adenosine,":[187],"GABA),":[188],"anxiety-type":[189],"behaviors":[190],"(assessed":[191],"novel":[194],"tank,":[195],"thigmotaxis,":[196],"shoaling),":[197],"changes":[200],"resulting":[201],"from":[202],"individual":[204],"co-exposure.":[206],"findings":[209],"those":[213],"rodent":[215],"revealing":[217],"similarities":[218],"across":[219],"species":[220],"identifying":[222],"conservation":[223],"mechanisms":[225],"potentially":[227],"reinforce":[228],"coaddiction.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-11-22T00:00:00"}
