{"id":"https://openalex.org/W3213089304","doi":"https://doi.org/10.1051/e3sconf/202132202016","title":"Effects of the microbiome manipulation on survival and GI tract development of larval zebrafish (Danio rerio)","display_name":"Effects of the microbiome manipulation on survival and GI tract development of larval zebrafish (Danio rerio)","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3213089304","doi":"https://doi.org/10.1051/e3sconf/202132202016","mag":"3213089304"},"language":"en","primary_location":{"id":"doi:10.1051/e3sconf/202132202016","doi":"https://doi.org/10.1051/e3sconf/202132202016","is_oa":true,"landing_page_url":"https://doi.org/10.1051/e3sconf/202132202016","pdf_url":"https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/98/e3sconf_isffs2021_02016.pdf","source":{"id":"https://openalex.org/S4210186093","display_name":"E3S Web of Conferences","issn_l":"2267-1242","issn":["2267-1242","2555-0403"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"E3S Web of Conferences","raw_type":"journal-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/98/e3sconf_isffs2021_02016.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014228089","display_name":"Uthpala M. Padeniya","orcid":"https://orcid.org/0000-0003-3436-1894","observed_orcids":["https://orcid.org/0000-0003-3436-1894"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Uthpala Padeniya","raw_affiliation_strings":["World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007793744","display_name":"Shafira Septriani","orcid":"https://orcid.org/0000-0002-7522-9948","observed_orcids":["https://orcid.org/0000-0002-7522-9948"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Shafira Septriani","raw_affiliation_strings":["World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077532977","display_name":"Arjay Pataueg","orcid":"https://orcid.org/0000-0002-2776-1219","observed_orcids":["https://orcid.org/0000-0002-2776-1219"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Arjay Pataueg","raw_affiliation_strings":["World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027428119","display_name":"Christopher Lyon Brown","orcid":"https://orcid.org/0000-0002-4578-3593","observed_orcids":["https://orcid.org/0000-0002-4578-3593"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Christopher L. Brown","raw_affiliation_strings":["World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Fisheries University Pilot Programme, Pukyong National University (PKNU), Busan, South Korea","institution_ids":["https://openalex.org/I8991828"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027428119"],"corresponding_institution_ids":["https://openalex.org/I8991828"],"apc_list":null,"apc_paid":null,"fwci":1.9613,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.80065898,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"322","issue":null,"first_page":"02016","last_page":"02016"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.0210999995470047,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zebrafish-larvae","display_name":"zebrafish larvae","score":0.9200000166893005},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.8600000143051147},{"id":"https://openalex.org/keywords/lactobacillus","display_name":"Lactobacillus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/larval-survival","display_name":"larval survival","score":0.9950000047683716},{"id":"https://openalex.org/keywords/gastrointestinal-tract-development","display_name":"gastrointestinal tract development","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lactic-acid-bacteria","display_name":"lactic acid bacteria","score":0.875},{"id":"https://openalex.org/keywords/amoxicillin","display_name":"amoxicillin","score":0.7730000019073486},{"id":"https://openalex.org/keywords/fish-farming","display_name":"fish farming","score":0.460999995470047}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8275513648986816},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.7451545000076294},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.7142785787582397},{"id":"https://openalex.org/C2780384893","wikidata":"https://www.wikidata.org/wiki/Q901804","display_name":"Danio","level":4,"score":0.6464235782623291},{"id":"https://openalex.org/C205501099","wikidata":"https://www.wikidata.org/wiki/Q188990","display_name":"Gram staining","level":3,"score":0.5663832426071167},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.5168098211288452},{"id":"https://openalex.org/C2777744765","wikidata":"https://www.wikidata.org/wiki/Q2734755","display_name":"Hatching","level":2,"score":0.5019488334655762},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.5017075538635254},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.477954626083374},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4645141661167145},{"id":"https://openalex.org/C110175623","wikidata":"https://www.wikidata.org/wiki/Q4284904","display_name":"Broodstock","level":4,"score":0.4385165572166443},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.4090285301208496},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.3805696368217468},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.29292112588882446},{"id":"https://openalex.org/C86909935","wikidata":"https://www.wikidata.org/wiki/Q188989","display_name":"Aquaculture","level":3,"score":0.19857379794120789},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.18729141354560852},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.16191178560256958},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.15699300169944763},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.10356932878494263},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1051/e3sconf/202132202016","doi":"https://doi.org/10.1051/e3sconf/202132202016","is_oa":true,"landing_page_url":"https://doi.org/10.1051/e3sconf/202132202016","pdf_url":"https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/98/e3sconf_isffs2021_02016.pdf","source":{"id":"https://openalex.org/S4210186093","display_name":"E3S Web of Conferences","issn_l":"2267-1242","issn":["2267-1242","2555-0403"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"E3S Web of Conferences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:c91232ee22d14a298885a106509bcb94","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c91232ee22d14a298885a106509bcb94","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"E3S Web of Conferences, Vol 322, p 02016 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1051/e3sconf/202132202016","doi":"https://doi.org/10.1051/e3sconf/202132202016","is_oa":true,"landing_page_url":"https://doi.org/10.1051/e3sconf/202132202016","pdf_url":"https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/98/e3sconf_isffs2021_02016.pdf","source":{"id":"https://openalex.org/S4210186093","display_name":"E3S Web of Conferences","issn_l":"2267-1242","issn":["2267-1242","2555-0403"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"E3S Web of Conferences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3213089304.pdf","grobid_xml":"https://content.openalex.org/works/W3213089304.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W58057490","https://openalex.org/W1004644096","https://openalex.org/W1789825216","https://openalex.org/W1986759107","https://openalex.org/W1993332255","https://openalex.org/W1997039338","https://openalex.org/W2056381830","https://openalex.org/W2067248851","https://openalex.org/W2078066066","https://openalex.org/W2080163690","https://openalex.org/W2081846987","https://openalex.org/W2124724575","https://openalex.org/W2136544929","https://openalex.org/W2168829895","https://openalex.org/W2206648169","https://openalex.org/W2232557022","https://openalex.org/W2624000494","https://openalex.org/W2626636048","https://openalex.org/W2749125701","https://openalex.org/W2765947271","https://openalex.org/W2769418101","https://openalex.org/W2887612794","https://openalex.org/W2971202383","https://openalex.org/W3010394331","https://openalex.org/W3034329852","https://openalex.org/W4245303697"],"related_works":["https://openalex.org/W6903274749","https://openalex.org/W4220786660","https://openalex.org/W4386000774","https://openalex.org/W2890098719","https://openalex.org/W6920692541","https://openalex.org/W4387662583","https://openalex.org/W6941108384","https://openalex.org/W4200395856","https://openalex.org/W2930406957","https://openalex.org/W4393234581"],"abstract_inverted_index":{"Microbial":[0],"diversity":[1],"within":[2],"an":[3,37],"aquatic":[4],"community":[5],"can":[6],"be":[7,125,175],"used":[8,70],"to":[9,79,97,127,158],"increase":[10],"the":[11,43,48,52,61,64,74,84,92,98,106,128,135,152,163,176,184,188],"growth":[12],"and":[13],"development":[14,62],"of":[15,33,51,63,76,83,130,178,187],"organisms.":[16],"In":[17,143],"this":[18,172],"study,":[19],"Zebrafish":[20],"larvae":[21,53,72,116],"were":[22],"reared":[23],"in":[24,86,105,134,140,151],"three":[25],"treatments":[26,111],"1)":[27],"a":[28,101,119],"probiotic":[29,136],"containing":[30],"17":[31],"strains":[32],"Lactobacillus":[34,179],"spp.,":[35],"2)":[36],"amoxicillin":[38],"solution,":[39],"3)":[40],"water":[41],"from":[42],"broodstock":[44],"culture":[45],"tank":[46],"as":[47],"control.":[49],"Survival":[50],"throughout":[54],"10":[55],"dpf":[56,78],"was":[57,69,89,112],"recorded.":[58,113],"To":[59],"determine":[60],"gastrointestinal":[65],"tract":[66,154],"DASPEI":[67,144],"stain":[68],"for":[71],"at":[73,155],"age":[75],"3":[77],"6dpf.":[80],"The":[81,114,167],"intensity":[82],"fluorescence":[85,150],"each":[87],"larva":[88],"observed":[90],"through":[91],"automated":[93],"digital":[94],"microscope.":[95],"According":[96],"experiment":[99],"results,":[100],"significant":[102],"difference":[103],"(P<0.0001)":[104],"survival":[107,121],"rates":[108],"among":[109],"all":[110],"probiotic-treated":[115],"(PTL)":[117],"had":[118],"higher":[120,185],"rate.":[122],"This":[123],"could":[124,173],"due":[126],"presence":[129,177],"lactic":[131],"acid":[132],"bacteria":[133],"treatment,":[137],"which":[138],"helps":[139],"enhancing":[141],"immunity.":[142],"staining,":[145],"also":[146,174],"PTL":[147],"exhibits":[148],"more":[149],"GI":[153],"24":[156],"hours":[157,160],"48":[159],"post-hatch":[161],"than":[162],"other":[164],"two":[165],"treatments.":[166],"main":[168],"possible":[169],"reason":[170],"behind":[171],"spp.":[180],"Which":[181],"directly":[182],"influences":[183],"activity":[186],"digestive":[189],"system.":[190]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2021-11-22T00:00:00"}