{"id":"https://openalex.org/W3212918800","doi":null,"title":"Temporary opening of the blood-brain barrier with the nitrone compound OKN-007.","display_name":"Temporary opening of the blood-brain barrier with the nitrone compound OKN-007.","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3212918800","mag":"3212918800","pmid":"https://pubmed.ncbi.nlm.nih.gov/34754607","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8569329"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:7462928","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8569329","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC8569329","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073331119","display_name":"Rheal A. Towner","orcid":"https://orcid.org/0000-0001-7368-8983","observed_orcids":["https://orcid.org/0000-0001-7368-8983"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rheal A Towner","raw_affiliation_strings":["Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation Oklahoma, OK, USA","Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation Oklahoma, OK, USA","institution_ids":["https://openalex.org/I30558944"]},{"raw_affiliation_string":"Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110581545","display_name":"Debra Saunders","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Debra Saunders","raw_affiliation_strings":["Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043870806","display_name":"Megan R. Lerner","orcid":"https://orcid.org/0000-0003-2645-8311","observed_orcids":["https://orcid.org/0000-0003-2645-8311"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan Lerner","raw_affiliation_strings":["Department of Surgery Research Laboratory, University of Oklahoma Health Sciences Center Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery Research Laboratory, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051793084","display_name":"Robert Silasi\u2010Mansat","orcid":"https://orcid.org/0000-0001-9590-6160","observed_orcids":["https://orcid.org/0000-0001-9590-6160"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Silasi Mansat","raw_affiliation_strings":["Cardiovascular Biology, Oklahoma Medical Research Foundation Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Biology, Oklahoma Medical Research Foundation Oklahoma, OK, USA","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102979725","display_name":"Tian Yuan","orcid":"https://orcid.org/0009-0006-4301-309X","observed_orcids":["https://orcid.org/0009-0006-4301-309X"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tian Yuan","raw_affiliation_strings":["Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051746262","display_name":"Dylan Barber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dylan Barber","raw_affiliation_strings":["Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA","institution_ids":["https://openalex.org/I30558944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076650843","display_name":"Janet Faakye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet Faakye","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020208515","display_name":"\u00c1d\u00e1m Ny\u00fal\u2010T\u00f3th","orcid":"https://orcid.org/0000-0001-6611-9539","observed_orcids":["https://orcid.org/0000-0001-6611-9539"]},"institutions":[{"id":"https://openalex.org/I2800351701","display_name":"HUN-REN Szegedi Biol\u00f3giai Kutat\u00f3k\u00f6zpont","ror":"https://ror.org/016gb1631","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4210122500","display_name":"Institute of Biophysics","ror":"https://ror.org/038synb39","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I4210122500","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4387152226","display_name":"Hungarian Research Network","ror":"https://ror.org/04w6pnc49","country_code":"HU","type":"other","lineage":["https://openalex.org/I4387152226"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["HU","US"],"is_corresponding":false,"raw_author_name":"Adam Nyul-Toth","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","Institute of Biophysics, Biological Research Centre, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) Szeged, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Institute of Biophysics, Biological Research Centre, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701","https://openalex.org/I4210122500","https://openalex.org/I4387152226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021282382","display_name":"Anna Csisz\u00e1r","orcid":"https://orcid.org/0000-0003-4842-6660","observed_orcids":["https://orcid.org/0000-0003-4842-6660"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Csiszar","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Neuroscience Program, University of Oklahoma Health Sciences Center Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007345136","display_name":"Beverley Greenwood\u2013Van Meerveld","orcid":"https://orcid.org/0000-0002-2647-1316","observed_orcids":["https://orcid.org/0000-0002-2647-1316"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beverley Greenwood-Van Meerveld","raw_affiliation_strings":["Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054614086","display_name":"Nataliya Smith","orcid":"https://orcid.org/0009-0000-8739-6164","observed_orcids":["https://orcid.org/0009-0000-8739-6164"]},"institutions":[{"id":"https://openalex.org/I30558944","display_name":"Oklahoma Medical Research Foundation","ror":"https://ror.org/035z6xf33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I30558944"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nataliya Smith","raw_affiliation_strings":["Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma, OK, USA","institution_ids":["https://openalex.org/I30558944"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8278,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.66283525,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"11","issue":"5","first_page":"363","last_page":"373"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.800000011920929},{"id":"https://openalex.org/keywords/nitrones","display_name":"nitrones","score":0.8199999928474426},{"id":"https://openalex.org/keywords/blood-brain-barrier-opening","display_name":"blood-brain barrier opening","score":0.7020000219345093},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.8119999766349792},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9330000281333923},{"id":"https://openalex.org/keywords/drug-permeability","display_name":"drug permeability","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8073092103004456},{"id":"https://openalex.org/C2778402981","wikidata":"https://www.wikidata.org/wiki/Q221694","display_name":"Blood\u2013brain barrier","level":3,"score":0.6940408945083618},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.6217042207717896},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4583527147769928},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.4298327565193176},{"id":"https://openalex.org/C64012434","wikidata":"https://www.wikidata.org/wiki/Q6839290","display_name":"Microbubbles","level":3,"score":0.4283391833305359},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29815179109573364},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1638089120388031},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15139511227607727},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.14750659465789795},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.09102153778076172},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:7462928","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8569329","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:34754607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34754607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of nuclear medicine and molecular imaging","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8569329","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8569329/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Nucl Med Mol Imaging","raw_type":"Text"},{"id":"pmh:oai:real.mtak.hu:137479","doi":null,"is_oa":false,"landing_page_url":"http://real.mtak.hu/137479/1/TownerAmJ.pdf","pdf_url":"http://real.mtak.hu/137479/1/TownerAmJ.pdf","source":{"id":"https://openalex.org/S4306400081","display_name":"Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210140733","host_organization_name":"Library and Information Centre of the Hungarian Academy of Sciences","host_organization_lineage":["https://openalex.org/I4210140733"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:3212918800","doi":null,"is_oa":false,"landing_page_url":"https://europepmc.org/article/MED/34754607","pdf_url":null,"source":{"id":"https://openalex.org/S2764345769","display_name":"American Journal of Nuclear Medicine and Molecular Imaging","issn_l":"2160-8407","issn":["2160-8407"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Nuclear Medicine and Molecular Imaging","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:7462928","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8569329","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W128151115","https://openalex.org/W1832070123","https://openalex.org/W1973613551","https://openalex.org/W1992190771","https://openalex.org/W2010418410","https://openalex.org/W2011583083","https://openalex.org/W2012111901","https://openalex.org/W2016618261","https://openalex.org/W2021648195","https://openalex.org/W2031062821","https://openalex.org/W2031806733","https://openalex.org/W2060060832","https://openalex.org/W2069514245","https://openalex.org/W2073077090","https://openalex.org/W2117691576","https://openalex.org/W2120914031","https://openalex.org/W2155957079","https://openalex.org/W2794427482","https://openalex.org/W3049428549"],"related_works":["https://openalex.org/W2903690391","https://openalex.org/W2074898332","https://openalex.org/W3111934081","https://openalex.org/W4416141252","https://openalex.org/W2946140916","https://openalex.org/W4252894894","https://openalex.org/W4409567116","https://openalex.org/W2611307227","https://openalex.org/W4416141311","https://openalex.org/W4281786990"],"abstract_inverted_index":{".":[0],"This":[1,36],"study":[2],"demonstrates":[3],"that":[4],"OKN-007":[5],"may":[6],"be":[7],"able":[8],"to":[9,15,30,56],"temporarily":[10],"open":[11],"up":[12],"the":[13,17,58],"BBB":[14],"augment":[16,57],"delivery":[18,59],"of":[19,60],"various":[20],"compounds":[21],"ranging":[22],"in":[23,47],"MW":[24],"from":[25],"as":[26,28,31,33],"small":[27],"~550":[29],"large":[32],"~470":[34],"kDa.":[35],"compound":[37],"is":[38,63],"an":[39],"investigational":[40],"new":[41],"drug":[42],"for":[43,53],"glioblastoma":[44],"(GBM)":[45],"therapy":[46],"clinical":[48],"trials.":[49],"The":[50],"translational":[51],"capability":[52],"human":[54],"use":[55],"non-BBB-permeable":[61],"drugs":[62],"extremely":[64],"high.":[65]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-11-22T00:00:00"}
