{"id":"https://openalex.org/W3212880366","doi":"https://doi.org/10.1002/9781119771951.ch8","title":"Metabolic Engineering Strategies to Enhance Microbial Production of Biopolymers","display_name":"Metabolic Engineering Strategies to Enhance Microbial Production of Biopolymers","publication_year":2021,"publication_date":"2021-10-25","ids":{"openalex":"https://openalex.org/W3212880366","doi":"https://doi.org/10.1002/9781119771951.ch8","mag":"3212880366"},"language":"en","primary_location":{"id":"doi:10.1002/9781119771951.ch8","doi":"https://doi.org/10.1002/9781119771951.ch8","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119771951.ch8","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomolecular Engineering Solutions for Renewable Specialty Chemicals","raw_type":"other"},"volume":{"id":"https://openalex.org/W4255400385","display_name":"Biomolecular Engineering Solutions for Renewable Specialty Chemicals"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085151542","display_name":"Shailendra Singh Shera","orcid":"https://orcid.org/0000-0003-2849-2185","observed_orcids":["https://orcid.org/0000-0003-2849-2185"]},"institutions":[{"id":"https://openalex.org/I2799634920","display_name":"Rama University","ror":"https://ror.org/02vhyd254","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799634920"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shailendra Singh Shera","raw_affiliation_strings":["Department of Biotechnology, Faculty of Engineering & Technology, Rama University, Kanpur, UP, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Faculty of Engineering & Technology, Rama University, Kanpur, UP, India","institution_ids":["https://openalex.org/I2799634920"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040166548","display_name":"Rathindra Mohan Banik","orcid":"https://orcid.org/0000-0002-6031-3143","observed_orcids":["https://orcid.org/0000-0002-6031-3143"]},"institutions":[{"id":"https://openalex.org/I56404289","display_name":"Indian Institute of Technology BHU","ror":"https://ror.org/01kh5gc44","country_code":"IN","type":"education","lineage":["https://openalex.org/I56404289","https://openalex.org/I91357014"]},{"id":"https://openalex.org/I91357014","display_name":"Banaras Hindu University","ror":"https://ror.org/04cdn2797","country_code":"IN","type":"education","lineage":["https://openalex.org/I91357014"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rathindra Mohan Banik","raw_affiliation_strings":["Bioprocess Technology Laboratory, School of Biochemical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi, UP, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioprocess Technology Laboratory, School of Biochemical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi, UP, India","institution_ids":["https://openalex.org/I56404289","https://openalex.org/I91357014"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"247","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14285","display_name":"Biopolymer Synthesis and Applications","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-engineering","display_name":"metabolic engineering","score":0.9240000247955322},{"id":"https://openalex.org/keywords/biopolymer-production","display_name":"biopolymer production","score":0.878000020980835},{"id":"https://openalex.org/keywords/microbial-fermentation","display_name":"microbial fermentation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/biopolymer-recovery","display_name":"biopolymer recovery","score":0.6629999876022339},{"id":"https://openalex.org/keywords/biopolymer-purification","display_name":"biopolymer purification","score":0.9599999785423279},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"synthetic biology","score":0.6639999747276306},{"id":"https://openalex.org/keywords/systems-biology","display_name":"systems biology","score":0.8999999761581421},{"id":"https://openalex.org/keywords/evolutionary-engineering","display_name":"evolutionary engineering","score":0.925000011920929}],"concepts":[{"id":"https://openalex.org/C6350086","wikidata":"https://www.wikidata.org/wiki/Q6822347","display_name":"Metabolic engineering","level":3,"score":0.7747902870178223},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.7193701267242432},{"id":"https://openalex.org/C2778348673","wikidata":"https://www.wikidata.org/wiki/Q739302","display_name":"Production (economics)","level":2,"score":0.5838907361030579},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.5357680916786194},{"id":"https://openalex.org/C179720865","wikidata":"https://www.wikidata.org/wiki/Q1550480","display_name":"Commodity chemicals","level":3,"score":0.5201040506362915},{"id":"https://openalex.org/C2778636629","wikidata":"https://www.wikidata.org/wiki/Q422649","display_name":"Biopolymer","level":3,"score":0.46558821201324463},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.43703848123550415},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.43359100818634033},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3242259919643402},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2973952293395996},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18032166361808777},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15531980991363525},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.12340801954269409},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781119771951.ch8","doi":"https://doi.org/10.1002/9781119771951.ch8","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119771951.ch8","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomolecular Engineering Solutions for Renewable Specialty Chemicals","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Responsible consumption and production","score":0.807699978351593,"id":"https://metadata.un.org/sdg/12"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W105663800","https://openalex.org/W839422381","https://openalex.org/W1512320585","https://openalex.org/W1559832400","https://openalex.org/W1560409804","https://openalex.org/W1880114654","https://openalex.org/W1963569152","https://openalex.org/W1973790218","https://openalex.org/W1978287170","https://openalex.org/W1989940093","https://openalex.org/W1998645140","https://openalex.org/W2012459591","https://openalex.org/W2016965453","https://openalex.org/W2018109858","https://openalex.org/W2027349735","https://openalex.org/W2037430612","https://openalex.org/W2038136017","https://openalex.org/W2044178571","https://openalex.org/W2047334633","https://openalex.org/W2073976721","https://openalex.org/W2076072707","https://openalex.org/W2077763891","https://openalex.org/W2081167153","https://openalex.org/W2092348209","https://openalex.org/W2093537097","https://openalex.org/W2094262910","https://openalex.org/W2098428537","https://openalex.org/W2102267945","https://openalex.org/W2102567175","https://openalex.org/W2116918487","https://openalex.org/W2117624454","https://openalex.org/W2117704770","https://openalex.org/W2123815079","https://openalex.org/W2159070250","https://openalex.org/W2220184817","https://openalex.org/W2230907825","https://openalex.org/W2231252456","https://openalex.org/W2256829711","https://openalex.org/W2282469096","https://openalex.org/W2404835098","https://openalex.org/W2412382304","https://openalex.org/W2464906938","https://openalex.org/W2466795701","https://openalex.org/W2468943383","https://openalex.org/W2471777900","https://openalex.org/W2490710929","https://openalex.org/W2516308683","https://openalex.org/W2520030234","https://openalex.org/W2521505040","https://openalex.org/W2548463564","https://openalex.org/W2565585402","https://openalex.org/W2568358245","https://openalex.org/W2595110869","https://openalex.org/W2606882994","https://openalex.org/W2614676559","https://openalex.org/W2630895790","https://openalex.org/W2766654837","https://openalex.org/W2772175224","https://openalex.org/W2783549818","https://openalex.org/W2786255107","https://openalex.org/W2790826364","https://openalex.org/W2796421800","https://openalex.org/W2799460746","https://openalex.org/W2799588030","https://openalex.org/W2800329064","https://openalex.org/W2802803660","https://openalex.org/W2810108330","https://openalex.org/W2911073577","https://openalex.org/W2912479692","https://openalex.org/W2915032335","https://openalex.org/W2915338207","https://openalex.org/W2936125014","https://openalex.org/W2944527133","https://openalex.org/W2946122436","https://openalex.org/W2946672701","https://openalex.org/W2963483340","https://openalex.org/W2978818150","https://openalex.org/W2986633422","https://openalex.org/W2999442951","https://openalex.org/W3002777374","https://openalex.org/W3008202828","https://openalex.org/W3015673430","https://openalex.org/W3017801182","https://openalex.org/W3021285251","https://openalex.org/W3023872366","https://openalex.org/W3035131136","https://openalex.org/W3035535272","https://openalex.org/W3035863394","https://openalex.org/W3042244364","https://openalex.org/W3048133162","https://openalex.org/W4252423015"],"related_works":["https://openalex.org/W4414652291","https://openalex.org/W3183732864","https://openalex.org/W3112155423","https://openalex.org/W3001961165","https://openalex.org/W4408800616","https://openalex.org/W4293738909","https://openalex.org/W4414000125","https://openalex.org/W2245487339","https://openalex.org/W3157644339","https://openalex.org/W2080023773"],"abstract_inverted_index":{"Biopolymers":[0],"are":[1],"used":[2],"as":[3,57],"plastics,":[4],"packaging":[5],"material,":[6,9],"clothing,":[7],"absorbent":[8],"medical":[10,14],"textiles,":[11],"and":[12,15,94,128,139,162,171],"in":[13,31,52,112,155],"health":[16],"care":[17],"sector":[18],"(pharmaceutical,":[19],"tissue":[20],"engineering).":[21],"The":[22],"multitude":[23],"of":[24,37,40,73,86,117],"applications":[25],"requires":[26],"that":[27],"biopolymers":[28,41,74],"be":[29],"produced":[30],"large":[32],"quantity.":[33],"However,":[34,78],"limited":[35,83],"availability":[36],"the":[38,109,118,136,158],"majority":[39],"or":[42],"cumbersome":[43],"extraction":[44],"process":[45,69],"from":[46],"natural":[47],"sources":[48],"poses":[49],"significant":[50],"hurdles":[51],"realizing":[53],"their":[54],"true":[55],"potential":[56],"a":[58,66],"commodity":[59],"product.":[60,120],"Microbial":[61],"fermentation":[62],"for":[63,70,114,165],"production":[64,72,92,110,116,169],"is":[65,81],"highly":[67],"sought":[68],"large-scale":[71,115],"with":[75,123,147,157],"desired":[76],"characteristics.":[77],"this":[79],"method":[80],"also":[82],"by":[84],"lack":[85],"high-producing":[87],"microbial":[88],"strain,":[89],"poorly":[90],"understood":[91],"pathway,":[93],"difficult":[95],"product":[96],"recovery":[97,170],"after":[98],"fermentation.":[99],"Metabolic":[100],"engineering":[101,130,133,153],"has":[102,134],"become":[103],"an":[104],"indispensable":[105],"tool":[106],"to":[107,141],"modify":[108],"pathway":[111],"microbes":[113],"targeted":[119],"In":[121],"combination":[122,156],"systems":[124],"biology,":[125,127],"synthetic":[126],"evolutionary":[129],"strategies,":[131],"metabolic":[132,152],"enabled":[135],"current":[137,159],"researchers":[138],"scientists":[140],"engineer":[142],"high-performance":[143],"industrially":[144],"competitive":[145],"strain":[146],"precision.":[148],"This":[149],"chapter":[150],"describes":[151],"strategies":[154],"state-of-the-art":[160],"techniques":[161],"tools":[163],"applied":[164],"enhancing":[166],"various":[167],"biopolymer":[168],"purification.":[172]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-11-22T00:00:00"}